BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0076.0010.p (429 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEI0269 [I] COG0821 Enzyme involved in the deoxyxylulose pathwa... 610 e-174 mll3792 [I] COG0821 Enzyme involved in the deoxyxylulose pathway... 600 e-171 SMc03888 [I] COG0821 Enzyme involved in the deoxyxylulose pathwa... 596 e-170 AGc4936 [I] COG0821 Enzyme involved in the deoxyxylulose pathway... 595 e-170 RSc1215 [I] COG0821 Enzyme involved in the deoxyxylulose pathway... 565 e-161 >BMEI0269 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Bme Brucella melitensis Length = 437 Score = 610 bits (1574), Expect = e-174, Method: Compositional matrix adjust. Identities = 303/407 (74%), Positives = 349/407 (85%) Query: 15 PAPRHQTTQVMVGNVAVGGGAPIVVQSMTNTDTADVDGTIAQVAALSRAGSEMVRITVDR 74 P PR Q+ V VG V VGG AP+VVQSMTNTDTADVD T+AQVAAL RAGSE+VRITVDR Sbjct: 29 PFPRRQSVGVSVGGVIVGGSAPVVVQSMTNTDTADVDSTVAQVAALHRAGSEIVRITVDR 88 Query: 75 EEAAAAVPHIRDGLRKRGITTPLIGDFHYIGHKLLAEYPDCAEALDKYRINPGNVGFKNK 134 +E+AAAVP IR+ L + G PL+GDFHYIGHKLLA++P CAEAL KYRINPGNVGFK+K Sbjct: 89 DESAAAVPKIRERLERLGHDVPLVGDFHYIGHKLLADHPACAEALAKYRINPGNVGFKDK 148 Query: 135 RDTQFADIIEIANKNNKPVRIGANWGSLDQELLTKLMDENTASANPRDARAVTREAMVQS 194 +D QFADI+E+A + +KPVRIG NWGSLDQELLT LMD N A P A+ V REA+VQS Sbjct: 149 KDKQFADIVEMAIRYDKPVRIGVNWGSLDQELLTTLMDRNQAEGAPLSAQDVMREAIVQS 208 Query: 195 ALLSAARAQELGMPKNRIILSAKVSAVQDLIAVYQEVVRRSDYAIHLGLTEAGMGSKGIV 254 AL+SA A+E+G+ +++IILSAKVS VQDLIAVY + +RS++A+HLGLTEAGMG+KGIV Sbjct: 209 ALISANLAEEIGLGRDKIILSAKVSQVQDLIAVYTMLAQRSNHALHLGLTEAGMGTKGIV 268 Query: 255 ASSAALGILLQQGIGDTIRISLTPEPGGDRTLEVQVAQELLQTMGFRTFVPLVAACPGCG 314 ASSAA+GILLQQGIGDTIRISLTPEPGGDRT EVQVAQELLQTMGFR FVP+VAACPGCG Sbjct: 269 ASSAAMGILLQQGIGDTIRISLTPEPGGDRTREVQVAQELLQTMGFRQFVPIVAACPGCG 328 Query: 315 RTTSTTFQELARSIQDFIRDEMPAWKTKYPGVEQLNVAVMGCIVNGPGESKHANIGISLP 374 RTTST FQELA++IQ+ IR MP W+ KYPGVE L+VAVMGCIVNGPGESKHA+IGISLP Sbjct: 329 RTTSTVFQELAQTIQEDIRRNMPLWREKYPGVEALSVAVMGCIVNGPGESKHADIGISLP 388 Query: 375 GTGEAPAAPVFVDGKKFRTLRGPGIAADFKALVIDYIDQRYGNGAKL 421 GTGE P+APVFVDGKK TLRGPGIA DF+ +V DYI+ R+G G K+ Sbjct: 389 GTGETPSAPVFVDGKKVTTLRGPGIAEDFQKMVADYIENRFGLGRKI 435 >mll3792 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Mlo Mesorhizobium loti Length = 417 Score = 600 bits (1547), Expect = e-171, Method: Compositional matrix adjust. Identities = 288/381 (75%), Positives = 330/381 (86%) Query: 40 QSMTNTDTADVDGTIAQVAALSRAGSEMVRITVDREEAAAAVPHIRDGLRKRGITTPLIG 99 QSMTNTDTAD+D T+AQVAAL RAGSE+VRITVDR+E+AAAVP I + L++ GI PL+G Sbjct: 33 QSMTNTDTADIDQTVAQVAALHRAGSEIVRITVDRDESAAAVPRIHERLQRLGINVPLVG 92 Query: 100 DFHYIGHKLLAEYPDCAEALDKYRINPGNVGFKNKRDTQFADIIEIANKNNKPVRIGANW 159 DFHYIGHKLLA++P CAEAL KYRINPGNVGFK+K+D QF DI+E+A K++KPVRIG NW Sbjct: 93 DFHYIGHKLLADHPACAEALAKYRINPGNVGFKDKKDRQFTDIVEMAIKHDKPVRIGVNW 152 Query: 160 GSLDQELLTKLMDENTASANPRDARAVTREAMVQSALLSAARAQELGMPKNRIILSAKVS 219 GSLDQELLT+LMD+N P A+ VTREA+VQSA+LSA A+E+G+ +++IILSAKVS Sbjct: 153 GSLDQELLTRLMDDNQDKGFPLTAQEVTREAIVQSAILSAEMAEEIGLGRDKIILSAKVS 212 Query: 220 AVQDLIAVYQEVVRRSDYAIHLGLTEAGMGSKGIVASSAALGILLQQGIGDTIRISLTPE 279 VQDLIAVY E+ RSD+A+HLGLTEAGMGSKGIVASSAA+GILLQQGIGDTIRISLTPE Sbjct: 213 GVQDLIAVYTELATRSDHALHLGLTEAGMGSKGIVASSAAMGILLQQGIGDTIRISLTPE 272 Query: 280 PGGDRTLEVQVAQELLQTMGFRTFVPLVAACPGCGRTTSTTFQELARSIQDFIRDEMPAW 339 P GDRT EVQVAQELLQTMGFR FVP+VAACPGCGRTTST FQELA++IQ +R MP W Sbjct: 273 PNGDRTREVQVAQELLQTMGFRQFVPIVAACPGCGRTTSTVFQELAQNIQADLRKNMPVW 332 Query: 340 KTKYPGVEQLNVAVMGCIVNGPGESKHANIGISLPGTGEAPAAPVFVDGKKFRTLRGPGI 399 + KYPGVE L VAVMGCIVNGPGESKHA+IGISLPGTGE P APVFVDGKK TLRG I Sbjct: 333 REKYPGVENLKVAVMGCIVNGPGESKHADIGISLPGTGETPTAPVFVDGKKAATLRGTSI 392 Query: 400 AADFKALVIDYIDQRYGNGAK 420 AADF+ +V DYI+QR+G G K Sbjct: 393 AADFEKMVTDYIEQRFGRGGK 413 >SMc03888 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Sme Sinorhizobium meliloti Length = 417 Score = 596 bits (1537), Expect = e-170, Method: Compositional matrix adjust. Identities = 285/379 (75%), Positives = 330/379 (87%) Query: 40 QSMTNTDTADVDGTIAQVAALSRAGSEMVRITVDREEAAAAVPHIRDGLRKRGITTPLIG 99 QSMTNTDTAD+D T+AQVAAL +AGSE+VRITVDR+E+AAAVP IR+ L + GI PL+G Sbjct: 34 QSMTNTDTADIDATVAQVAALHKAGSELVRITVDRDESAAAVPKIRERLLRLGIDVPLVG 93 Query: 100 DFHYIGHKLLAEYPDCAEALDKYRINPGNVGFKNKRDTQFADIIEIANKNNKPVRIGANW 159 DFHYIGHKLLA++P CAEAL KYRINPGNVGFK+K+D QFA+IIE+A + +KPVRIG NW Sbjct: 94 DFHYIGHKLLADHPACAEALAKYRINPGNVGFKDKKDKQFAEIIEMAIRYDKPVRIGVNW 153 Query: 160 GSLDQELLTKLMDENTASANPRDARAVTREAMVQSALLSAARAQELGMPKNRIILSAKVS 219 GSLDQELLT+LMD N A+ +P A+ V RE +VQSALLSA A+ELG+P++RIILSAKVS Sbjct: 154 GSLDQELLTRLMDANQANGSPLTAQQVMRETIVQSALLSAELAEELGLPRSRIILSAKVS 213 Query: 220 AVQDLIAVYQEVVRRSDYAIHLGLTEAGMGSKGIVASSAALGILLQQGIGDTIRISLTPE 279 VQDLIAVY + RS +A+HLGLTEAGMG+KGIVASSA+LGIL+QQGIGDTIRISLTPE Sbjct: 214 GVQDLIAVYAMLAARSVHALHLGLTEAGMGTKGIVASSASLGILMQQGIGDTIRISLTPE 273 Query: 280 PGGDRTLEVQVAQELLQTMGFRTFVPLVAACPGCGRTTSTTFQELARSIQDFIRDEMPAW 339 PGGDRT EVQVAQELLQ MGFR F+P+VAACPGCGRTTST FQELA+ IQ+ IR MP W Sbjct: 274 PGGDRTREVQVAQELLQVMGFRQFIPVVAACPGCGRTTSTVFQELAQKIQEDIRASMPVW 333 Query: 340 KTKYPGVEQLNVAVMGCIVNGPGESKHANIGISLPGTGEAPAAPVFVDGKKFRTLRGPGI 399 + KYPGVE L VAVMGCIVNGPGESKHA+IGISLPGTGE PAAPVF+DG+K TLRGP I Sbjct: 334 REKYPGVEALKVAVMGCIVNGPGESKHADIGISLPGTGEMPAAPVFIDGQKALTLRGPKI 393 Query: 400 AADFKALVIDYIDQRYGNG 418 A DF+ LV DYI++R+G+G Sbjct: 394 AEDFQLLVADYIEKRFGHG 412 >AGc4936 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 440 Score = 595 bits (1533), Expect = e-170, Method: Compositional matrix adjust. Identities = 299/402 (74%), Positives = 345/402 (85%) Query: 15 PAPRHQTTQVMVGNVAVGGGAPIVVQSMTNTDTADVDGTIAQVAALSRAGSEMVRITVDR 74 P PR + V VG V VGGGAP+VVQSMTNTDTAD+D T+ QVAAL +AGSEMVRITVDR Sbjct: 33 PKPRRASVAVDVGGVIVGGGAPVVVQSMTNTDTADIDATVRQVAALFQAGSEMVRITVDR 92 Query: 75 EEAAAAVPHIRDGLRKRGITTPLIGDFHYIGHKLLAEYPDCAEALDKYRINPGNVGFKNK 134 +E+AAAVP IR+ L + G+ PLIGDFHYIGHKLLA++P CAEAL KYRINPGNVGFK+K Sbjct: 93 DESAAAVPKIRERLLRLGMDVPLIGDFHYIGHKLLADHPACAEALAKYRINPGNVGFKDK 152 Query: 135 RDTQFADIIEIANKNNKPVRIGANWGSLDQELLTKLMDENTASANPRDARAVTREAMVQS 194 +D QF +I+E+A + +KPVRIG NWGSLDQELLT LMD N P AR VTREA+VQS Sbjct: 153 KDKQFGEIVEMAIRYDKPVRIGVNWGSLDQELLTTLMDRNKEQGFPLSARQVTREAIVQS 212 Query: 195 ALLSAARAQELGMPKNRIILSAKVSAVQDLIAVYQEVVRRSDYAIHLGLTEAGMGSKGIV 254 AL+SA A+E+G+P+NRIILSAKVS VQDLIAVY + RS++A+HLGLTEAGMGSKGIV Sbjct: 213 ALISAELAEEIGLPRNRIILSAKVSQVQDLIAVYSMLSERSNHALHLGLTEAGMGSKGIV 272 Query: 255 ASSAALGILLQQGIGDTIRISLTPEPGGDRTLEVQVAQELLQTMGFRTFVPLVAACPGCG 314 ASSAA+G +LQ GIGDTIR+SLTPEP GDRT EVQVAQELLQ MGFR F+P+VAACPGCG Sbjct: 273 ASSAAMGYVLQHGIGDTIRVSLTPEPNGDRTREVQVAQELLQVMGFRQFIPVVAACPGCG 332 Query: 315 RTTSTTFQELARSIQDFIRDEMPAWKTKYPGVEQLNVAVMGCIVNGPGESKHANIGISLP 374 RTTST FQELA++IQ+ IR MP W+ KYPGVE LNVAVMGCIVNGPGESKHA+IGISLP Sbjct: 333 RTTSTVFQELAQNIQNDIRKNMPIWREKYPGVEALNVAVMGCIVNGPGESKHADIGISLP 392 Query: 375 GTGEAPAAPVFVDGKKFRTLRGPGIAADFKALVIDYIDQRYG 416 GTGE+PAAPVF+DG+K TLRGP IAADF+ALVIDYI++R+G Sbjct: 393 GTGESPAAPVFIDGEKALTLRGPNIAADFEALVIDYIEKRFG 434 >RSc1215 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Rso Ralstonia solanacearum Length = 431 Score = 565 bits (1455), Expect = e-161, Method: Compositional matrix adjust. Identities = 278/407 (68%), Positives = 324/407 (79%), Gaps = 4/407 (0%) Query: 14 GPAPRHQT--TQVMVGN--VAVGGGAPIVVQSMTNTDTADVDGTIAQVAALSRAGSEMVR 69 GP PR + ++ G V VGG AP+ VQSMTNTDTAD GT QV L+R GSE+VR Sbjct: 15 GPLPRRHSRAAEIRWGERLVRVGGDAPVCVQSMTNTDTADAIGTAIQVKELARTGSELVR 74 Query: 70 ITVDREEAAAAVPHIRDGLRKRGITTPLIGDFHYIGHKLLAEYPDCAEALDKYRINPGNV 129 ITV+ EAAAAVP IR+ L + GI PL+GDFHY GHKLL ++P CAEAL KYRINPGNV Sbjct: 75 ITVNTPEAAAAVPAIREQLDRMGIDVPLVGDFHYNGHKLLQDHPACAEALSKYRINPGNV 134 Query: 130 GFKNKRDTQFADIIEIANKNNKPVRIGANWGSLDQELLTKLMDENTASANPRDARAVTRE 189 G KRDTQFA +IE A + KPVRIG NWGSLDQ+LL ++MDEN A P DARAV E Sbjct: 135 GQGAKRDTQFAQMIETACRYGKPVRIGVNWGSLDQDLLARIMDENAQRAAPWDARAVMIE 194 Query: 190 AMVQSALLSAARAQELGMPKNRIILSAKVSAVQDLIAVYQEVVRRSDYAIHLGLTEAGMG 249 A++ SA+ SA +A+E+G+P ++IILS KVSAVQDLIAVY+E+ RR DYA+HLGLTEAGMG Sbjct: 195 ALITSAIESARKAEEIGLPGSQIILSCKVSAVQDLIAVYRELARRCDYALHLGLTEAGMG 254 Query: 250 SKGIVASSAALGILLQQGIGDTIRISLTPEPGGDRTLEVQVAQELLQTMGFRTFVPLVAA 309 SKGIVAS+AAL +LLQ+GIGDTIRISLTPEPG R EV VAQE+LQTMG R F P+V A Sbjct: 255 SKGIVASTAALSVLLQEGIGDTIRISLTPEPGAPREKEVIVAQEILQTMGLRNFTPMVIA 314 Query: 310 CPGCGRTTSTTFQELARSIQDFIRDEMPAWKTKYPGVEQLNVAVMGCIVNGPGESKHANI 369 CPGCGRTTST FQELA IQ ++R++MP WKT+YPGVE +NVAVMGCIVNGPGESKHANI Sbjct: 315 CPGCGRTTSTVFQELAARIQSYLREQMPVWKTQYPGVEDMNVAVMGCIVNGPGESKHANI 374 Query: 370 GISLPGTGEAPAAPVFVDGKKFRTLRGPGIAADFKALVIDYIDQRYG 416 GISLPGTGE+PAAPVFVDG K +TLRG IA DF+ +V +Y+ YG Sbjct: 375 GISLPGTGESPAAPVFVDGVKVKTLRGERIAEDFQVIVDEYVRTHYG 421