BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0076.0008.p (318 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0519 [GER] COG0697 Permeases of the drug/metabolite transport... 206 6e-53 BMEI0982 [GER] COG0697 Permeases of the drug/metabolite transpor... 181 2e-45 PA1411 [GER] COG0697 Permeases of the drug/metabolite transporte... 170 4e-42 mlr0335 [GER] COG0697 Permeases of the drug/metabolite transport... 156 5e-38 BS_yoaV [GER] COG0697 Permeases of the drug/metabolite transport... 91 2e-18 >RSc0519 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 301 Score = 206 bits (524), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 122/284 (42%), Positives = 180/284 (63%), Gaps = 3/284 (1%) Query: 24 AIAVMLMLCVSWGFNQLAVKLALPDVPPMLQALIRSAGALPVMLIVGHLRGVKFFERDGT 83 AI +M++LC+ WG Q+A+K+A+ DV P++QA +RSA A ++L RG + RDGT Sbjct: 16 AIGLMVVLCLCWGLQQVAIKVAVHDVGPVMQAGVRSAIASVLVLAFALWRGTRLTLRDGT 75 Query: 84 LVPGIIAGLMFGCEFVLIFTGLVFTSASRASVFLYTAPFFVALGSHQFL-GERLSTVQWS 142 L G+ AG +FG EF+ IF GL T+ASR +VFLYTAP F ALG H F+ GE L QW Sbjct: 76 LPGGLAAGTLFGIEFLCIFIGLGHTTASRMAVFLYTAPIFTALGLHAFVPGEHLRPRQWL 135 Query: 143 GLALSFAGVALAI--GVPQPNVDAKVLLGDLMVVGGGALWAATTLVAKGTGWRKAAPEKA 200 G+ ++FAG+ LA G+ P LGD + V G LW+ATTLV + + +A K Sbjct: 136 GIGVAFAGMVLAFADGMLHPAAGPSTSLGDALGVLAGVLWSATTLVVRASRLSEAPAAKT 195 Query: 201 LGYQVAISIPILGLAAWIAGERIEHVPSALSISLLAYQAVWVVGCTFVIWFAMVKTYSAS 260 L YQ+A+S +L A G+ + +++ LAYQ+V + ++++WF +++ Y AS Sbjct: 196 LLYQLAVSAVLLLTMAAGTGQAWTANLTPTALASLAYQSVLIAFASYLVWFWLLRRYLAS 255 Query: 261 KLSAFTFVTPLFGVVAAYFIMHDTLTAVFGVAALLVIAGLYLVN 304 +LS F+F+TP+FGV A ++HD + F +AA LV++G+ LVN Sbjct: 256 RLSVFSFLTPMFGVAFAVLLLHDPVGLRFALAAALVLSGILLVN 299 >BMEI0982 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bme Brucella melitensis Length = 307 Score = 181 bits (459), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 115/286 (40%), Positives = 167/286 (58%), Gaps = 7/286 (2%) Query: 24 AIAVMLMLCVSWGFNQLAVKLALPDVPPMLQALIRSA-GALPVMLIVGHLRGVKFFERDG 82 AIA+++ + WG NQ+A+K+ PML A RSA G L V L R + F+RD Sbjct: 19 AIALVIFIMFGWGLNQVAIKIGNWGFNPMLMAAGRSALGGLCVFLWCCW-RRIPLFKRDD 77 Query: 83 TLVPGIIAGLMFGCEFVLIFTGLVFTSASRASVFLYTAPFFVALGSHQFLGERLSTVQWS 142 TL PG++AG++FG EFVLIF + TS R ++ + PF+VA+GSH LGER+S + Sbjct: 78 TLKPGLVAGMLFGTEFVLIFVAMDLTSVGRVTLMMNVMPFWVAIGSHFLLGERMSVRAFI 137 Query: 143 GLALSFAGVALAIGVPQPNVDAKVLLGDLMVVGGGALWAATTLVAKGTGWRKAAPEKALG 202 G+ ++F GV L GDL+ + G LW TTLV K T APEK L Sbjct: 138 GMCIAFFGVFLVFSDYVSRPGPYAFYGDLLALFSGVLWGLTTLVIKRTKLACTAPEKTLL 197 Query: 203 YQVAIS--IPILGLAAWIAGERIEHVPSALSISLLAYQAVWVVGCTFVIWFAMVKTYSAS 260 YQ+ ++ +P+ +A ++G I + P +S+S +QA++VV T+ +WF MV+ Y AS Sbjct: 198 YQLVVASLVPLPFIA--LSGPLIRN-PDIISVSAFLFQAIFVVAFTYPLWFWMVRRYPAS 254 Query: 261 KLSAFTFVTPLFGVVAAYFIMHDTLTAVFGVAALLVIAGLYLVNKP 306 KLS F F+TP FGV+ + I+ + L+ A L+ GL ++NKP Sbjct: 255 KLSNFAFLTPAFGVLLSGIILDEPLSWKIFAALALIGCGLLIINKP 300 >PA1411 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 303 Score = 170 bits (430), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 110/287 (38%), Positives = 165/287 (57%), Gaps = 3/287 (1%) Query: 24 AIAVMLMLCVSWGFNQLAVKLALPDVPPMLQALIRSAGALPVMLIVGHLRGVKFFERDGT 83 A ML+LCV WG Q+ +K A D+ P++QA IRS A ++ ++ RG R GT Sbjct: 9 AFQTMLLLCVIWGIQQVTIKWAATDIAPVMQAAIRSGIAAALVGLLMCWRGGWEGLRQGT 68 Query: 84 LVPGIIAGLMFGCEFVLIFTGLVFTSASRASVFLYTAPFFVALGSHQFL-GERLSTVQWS 142 L G++ G +F EF+ I GL +T+AS SVFLYTAP F ALG H L ERL +QW Sbjct: 69 LGAGLLTGTLFALEFLFIALGLQYTTASHMSVFLYTAPIFSALGLHFLLPSERLRPLQWL 128 Query: 143 GLALSFAGVALAIG--VPQPNVDAKVLLGDLMVVGGGALWAATTLVAKGTGWRKAAPEKA 200 G+A+ F G+A+A G + +D ++LLGD + G W ATT+ +GT +A P Sbjct: 129 GVAVCFGGIAVAFGGGLSWAEMDGRMLLGDAFGLLAGMSWGATTVAVRGTRLSEAPPSLT 188 Query: 201 LGYQVAISIPILGLAAWIAGERIEHVPSALSISLLAYQAVWVVGCTFVIWFAMVKTYSAS 260 L YQ+ ++ L L A +G+ E + +S + + +Q V V ++ WF +++ Y A+ Sbjct: 189 LFYQLFVACAGLLLIALFSGQFGEVRWTPVSTASVLFQGVVVSFASYFCWFWLLRRYLAN 248 Query: 261 KLSAFTFVTPLFGVVAAYFIMHDTLTAVFGVAALLVIAGLYLVNKPD 307 L+ F+F+TPLFGV ++ + L+ F A LV+AG+ LV+ Sbjct: 249 NLAIFSFMTPLFGVTFGVLLLGEPLSLNFVAGAALVLAGITLVSGEQ 295 >mlr0335 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 290 Score = 156 bits (395), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 98/287 (34%), Positives = 165/287 (57%), Gaps = 2/287 (0%) Query: 26 AVMLMLCVSWGFNQLAVKLALPDVPPMLQALIRSAGALPVMLIVGHLRGVKFFERDGTLV 85 A+M+ L SWG N +A K++ P+ ++ RS + + RG+ F RDGTL+ Sbjct: 5 AIMVGLTFSWGLNYVAAKISYAGYDPVFLSIARSIIGGFCVFLWCRWRGIALFTRDGTLL 64 Query: 86 PGIIAGLMFGCEFVLIFTGLVFTSASRASVFLYTAPFFVALGSHQFLGERLSTVQWSGLA 145 GI G++FG EF+ ++ GL T+ +R ++ + + PF++ +G H LGE++ T++ Sbjct: 65 AGIAVGVLFGIEFLCLYVGLEHTTVARNTLLVNSMPFWMLIGGHLLLGEQI-TMRKFLGL 123 Query: 146 LSFAGVALAIGVPQPNVDAKVLLGDLMVVGGGALWAATTLVAKGTGWRKAAPEKALGYQV 205 L A+ + +L GDL+ +G G WA T ++ K + +A+ EK L YQ+ Sbjct: 124 LLAFAGLAAVFSDKLGGGGDMLFGDLLSLGSGFFWALTNILIKRSKLVEASAEKLLLYQL 183 Query: 206 AISIPILGLAAWIAGERIEHVPSALSISLLAYQAVWVVGCTFVIWFAMVKTYSASKLSAF 265 A + + L +AG + PS L L +QA+++V T+V+WF +++ Y AS LS+F Sbjct: 184 AGAAMVGILVLPLAGPPVRD-PSLLPTLALLFQAIYIVAFTYVLWFWLLRRYPASGLSSF 242 Query: 266 TFVTPLFGVVAAYFIMHDTLTAVFGVAALLVIAGLYLVNKPDPKVTP 312 TF++P+FGV+ I+++ LT +A L+ AGL +VN+P K+TP Sbjct: 243 TFLSPVFGVLCGAVILNEPLTMRIFLALGLIAAGLIIVNRPARKLTP 289 >BS_yoaV [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bsu Bacillus subtilis Length = 292 Score = 91.3 bits (225), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 83/300 (27%), Positives = 138/300 (46%), Gaps = 44/300 (14%) Query: 23 GAIAVMLMLCVSWGFNQLAVKLALPDVPPMLQALIR-SAGALPVMLIVGHLRGVKFFERD 81 G I+V L+ WG+ +A+K+ + D+PP+L + +R GA+P+ LI+ ++ K + Sbjct: 7 GIISVTLI----WGYTWVAMKVGIHDIPPLLFSGLRLFIGAVPLFLIL-FIQRKKLSIQK 61 Query: 82 GTLVPGIIAGLMFGCEFVLIFT-GLVFTSASRASVFLYTAPFFVALGSHQFLGERLSTVQ 140 L II L+ G ++ I T G+ F + + SV +YT P FV + SH L E+++ + Sbjct: 62 EHLKSYIIMSLLMGLGYMGILTYGMQFVDSGKTSVLVYTMPIFVTVISHFSLNEKMNVYK 121 Query: 141 WSGLALSFAGVALAIGVPQPNVDAKVLLGDLMVVGGGALWAATTLVAKGTGWRKAAPEKA 200 GL G+ G N+D L G+L V+ W + +K Sbjct: 122 TMGLVCGLFGLLFIFGKEMLNIDQSALFGELCVLVAALSWGIANVFSK------------ 169 Query: 201 LGYQVAISIPILGLAAW----------IAGERIEHVPSALSISLLAYQAVWVV------- 243 L ++ I I+ + AW + E VPSA YQAVW + Sbjct: 170 LQFK---HIDIIHMNAWHLMMGAVMLLVFSFIFEAVPSA----EWTYQAVWSLLFNGLLS 222 Query: 244 -GCTFVIWFAMVKTYSASKLSAFTFVTPLFGVVAAYFIMHDTLTAVFGVAALLVIAGLYL 302 G TFV+WF ++ ASK S P+ + + +H+ +T + ALL+ G+++ Sbjct: 223 TGFTFVVWFWVLNQIQASKASMALMFVPVLALFFGWLQLHEQITINIILGALLICCGIFM 282