BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0076.0001.p (233 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0244 [E] COG0169 Shikimate 5-dehydrogenase Pae Pseudomonas aer... 147 3e-35 Cgl0419 [E] COG0169 Shikimate 5-dehydrogenase Cgl Corynebacteriu... 145 1e-34 RSp1398 [E] COG0169 Shikimate 5-dehydrogenase Rso Ralstonia sola... 137 1e-32 MK0117 [E] COG0169 Shikimate 5-dehydrogenase Mka Methanopyrus ka... 137 2e-32 AGl673 [E] COG0169 Shikimate 5-dehydrogenase Atu Agrobacterium t... 129 4e-30 >PA0244 [E] COG0169 Shikimate 5-dehydrogenase Pae Pseudomonas aeruginosa Length = 284 Score = 147 bits (370), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 96/205 (46%), Positives = 125/205 (60%), Gaps = 5/205 (2%) Query: 8 LGFAGVNVTFPYKEAVVDLIDSLAPDARAIGAVNTIVVDDARLVGHNTDASGFVRAITPL 67 LGF G+NVTFP K+A++ L+D L+ +AR IGAVNT+V+ D R +GHNTD GF Sbjct: 63 LGFTGLNVTFPCKQAIIPLLDDLSAEARGIGAVNTVVLRDGRRIGHNTDCLGFAEGFRRG 122 Query: 68 LASTPRGPIALIGAGGVGKAIAFALAGLGVGELRIFDADAAKVARLAGQLAGRH--AVRG 125 LA PR + +GAGG G A+A AL GV L +FD D A+ LA L +H A R Sbjct: 123 LADAPRQRVVQMGAGGAGAAVAHALLAEGVERLVLFDVDPARAQALADNL-NQHFGAPRA 181 Query: 126 VAGVE--AAVDGATGVVNATPVGMLPNRDSPVPDALLHPSMWVADAVYTPLWTPLLLAAK 183 +AG + A+ A G+VN TPVGM PVP LL +WVA+ +Y PL T LL A+ Sbjct: 182 LAGSDLAGALGDAQGLVNTTPVGMAKLPGMPVPAELLRADLWVAEVIYFPLETELLRQAR 241 Query: 184 AKGSKVLTGRDLAIYAAADAFELFT 208 A G + L G +A++ A AFELF+ Sbjct: 242 ALGCRTLDGGTMAVFQAVKAFELFS 266 >Cgl0419 [E] COG0169 Shikimate 5-dehydrogenase Cgl Corynebacterium glutamicum Length = 283 Score = 145 bits (365), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 95/227 (41%), Positives = 130/227 (57%), Gaps = 6/227 (2%) Query: 1 MLEGIRRLGFAGVNVTFPYKEAVVDLIDSLAPDARAIGAVNTIVVD-DARLVGHNTDASG 59 +L+ LGF G+N+T PYK+AV+ L+D ++ A +GAVNT+V+D GHNTD SG Sbjct: 54 LLDAALYLGFNGLNITHPYKQAVLPLLDEVSEQATQLGAVNTVVIDATGHTTGHNTDVSG 113 Query: 60 FVRAITPLLASTPRGPIALIGAGGVGKAIAFALAGLGVGELRIFDADAAKVARLA---GQ 116 F R + L + + +GAGGVG A+A+AL GV +L++ D D ++ LA Sbjct: 114 FGRGMEEGLPNAKLDSVVQVGAGGVGNAVAYALVTHGVQKLQVADLDTSRAQALADVINN 173 Query: 117 LAGRHAVRGV--AGVEAAVDGATGVVNATPVGMLPNRDSPVPDALLHPSMWVADAVYTPL 174 GR AV GV G+E + A GVVNATP+GM + + + L WV D VY P+ Sbjct: 174 AVGREAVVGVDARGIEDVIAAADGVVNATPMGMPAHPGTAFDVSCLTKDHWVGDVVYMPI 233 Query: 175 WTPLLLAAKAKGSKVLTGRDLAIYAAADAFELFTTMMPSTDVMANAF 221 T LL AA+A G + L G +AI+ A DAF LFT + P M F Sbjct: 234 ETELLKAARALGCETLDGTRMAIHQAVDAFRLFTGLEPDVSRMRETF 280 >RSp1398 [E] COG0169 Shikimate 5-dehydrogenase Rso Ralstonia solanacearum Length = 315 Score = 137 bits (346), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 100/236 (42%), Positives = 135/236 (57%), Gaps = 3/236 (1%) Query: 1 MLEGIRRLGFAGVNVTFPYKEAVVDLIDSLAPDARAIGAVNTIVVDDARLVGHNTDASGF 60 +L R GFAG+NVT P K+ V+ +D L+ DARA+GAVNT+V D+ R +GHNTD GF Sbjct: 58 LLTAAERFGFAGLNVTHPCKQRVLHYLDDLSDDARALGAVNTVVFDNGRRIGHNTDWWGF 117 Query: 61 VRAITPLLASTPRGPIALIGAGGVGKAIAFALAGLGVGELRIFDADAAKVARLAGQLAGR 120 + L P G + +GAGG G A+A A+ LG L +FD + + +LA L GR Sbjct: 118 AESFKRGLPGAPMGQVVQLGAGGAGAAVAHAMLTLGAQSLTLFDVEPERARQLAASLCGR 177 Query: 121 HAV-RGVAGVE--AAVDGATGVVNATPVGMLPNRDSPVPDALLHPSMWVADAVYTPLWTP 177 R AG + AA+ A G+V+ATP GM + P+P LL WVA+ VY PL T Sbjct: 178 FGPGRAQAGTDLAAAMAAADGLVHATPTGMAGHPGLPLPPDLLQSRHWVAEIVYFPLETE 237 Query: 178 LLLAAKAKGSKVLTGRDLAIYAAADAFELFTTMMPSTDVMANAFDAVMAARYSVPA 233 LL A+A G + L G +A++ A AFELFT + P+ M F A+ A + A Sbjct: 238 LLRRARALGCRTLDGGGMAVFQAVGAFELFTGIAPNAHRMLAHFAALQDAEATAHA 293 >MK0117 [E] COG0169 Shikimate 5-dehydrogenase Mka Methanopyrus kandleri AV19 Length = 290 Score = 137 bits (344), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 92/232 (39%), Positives = 127/232 (54%), Gaps = 13/232 (5%) Query: 2 LEGIRR----LGFAGVNVTFPYKEAVVDLIDSLAPDARAIGAVNTIVVDDARLVGHNTDA 57 LEG R LG G+NVT P+KEAV++L D L DA IGAVNT+ ++ G NTD Sbjct: 53 LEGAVRGAADLGIVGLNVTIPHKEAVMELCDELDRDAELIGAVNTVRFSRGKIEGFNTDG 112 Query: 58 SGFVRAITPLLASTPRGPIALI-GAGGVGKAIAFALAGLGVGELRIFDADAAKVARLAGQ 116 GF+RA+ PRG ++I GAGG +A++F LA G E+ I + + RLA + Sbjct: 113 EGFLRALREETYFDPRGTKSVILGAGGAARAVSFKLATEGADEIVIANRTVDRAERLAEE 172 Query: 117 LAGRHAVR----GVAG--VEAAVDGATGVVNATPVGMLPNRDSP--VPDALLHPSMWVAD 168 L + V+ G+ G +E + A +V+ATPVGM PN D P V +H + V D Sbjct: 173 LKEKVGVKARAIGLDGDEIERELRDADLLVDATPVGMYPNEDEPPLVTADQMHEDLIVND 232 Query: 169 AVYTPLWTPLLLAAKAKGSKVLTGRDLAIYAAADAFELFTTMMPSTDVMANA 220 VY P T LL A+ G+ ++G + +Y A AFEL+T +VM A Sbjct: 233 LVYNPPRTRLLEEAEKAGATPVSGVGMLVYQGALAFELWTGEEAPVEVMREA 284 >AGl673 [E] COG0169 Shikimate 5-dehydrogenase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 289 Score = 129 bits (325), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 89/231 (38%), Positives = 120/231 (51%), Gaps = 3/231 (1%) Query: 1 MLEGIRRLGFAGVNVTFPYKEAVVDLIDSLAPDARAIGAVNTIVVDDARLVGHNTDASGF 60 +L+ + GFAG N+T P+K+AV+ + L+ DAR +GAVNT+V D R +GHNTD GF Sbjct: 56 LLDELEARGFAGTNITHPFKQAVIPHLHELSDDARMLGAVNTVVFRDGRRIGHNTDWYGF 115 Query: 61 VRAITPLLASTPRGPIALIGAGGVGKAIAFALAGLGVGELRIFDADAAKVARLAGQLAGR 120 + L R L+GAGG G A+A A L + L IFD D + RLA +L R Sbjct: 116 YESFVRGLPDAKRDRALLVGAGGAGVAVAHAALKLDIIRLDIFDRDFPRAERLADELNAR 175 Query: 121 HAVRGVAGVEAAVDG---ATGVVNATPVGMLPNRDSPVPDALLHPSMWVADAVYTPLWTP 177 V+ D A G+++ATP+GM + PV L+ WVAD VY PL T Sbjct: 176 FGEGRAFAVKDPADSLPFADGLIHATPMGMPAHPGMPVAAELIEQKHWVADIVYMPLVTE 235 Query: 178 LLLAAKAKGSKVLTGRDLAIYAAADAFELFTTMMPSTDVMANAFDAVMAAR 228 LL A +KG + L G + ++ A AF LF P M F + A Sbjct: 236 LLATAASKGCRTLPGGGMTVFQAVGAFRLFCGREPDAKRMTAHFTELCMAE 286