BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0073.0025.p (250 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC0838 [V] COG1131 ABC-type multidrug transport system, ATPase c... 333 2e-91 TM0793 [V] COG1131 ABC-type multidrug transport system, ATPase c... 207 2e-53 CAC0268 [V] COG1131 ABC-type multidrug transport system, ATPase ... 196 3e-50 PAB1696 [V] COG1131 ABC-type multidrug transport system, ATPase ... 187 1e-47 PH1230 [V] COG1131 ABC-type multidrug transport system, ATPase c... 186 4e-47 >CC0838 [V] COG1131 ABC-type multidrug transport system, ATPase component Ccr Caulobacter vibrioides Length = 250 Score = 333 bits (854), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 168/244 (68%), Positives = 197/244 (80%), Gaps = 2/244 (0%) Query: 7 ALAVRGLTKRFDRPAVDALDLTIRVGEFYALLGPNGAGKTTTLRMVAGLLRPDAGSVSIL 66 AL VRGL+K F +PAV LDLT+R GE YALLGPNGAGKTTTLRMVAGL +PDAG ++I Sbjct: 8 ALVVRGLSKTFAKPAVSNLDLTVRAGELYALLGPNGAGKTTTLRMVAGLTQPDAGEIAIF 67 Query: 67 GTDALADPVSAKQVMAWVSDEPMIYDKLTPLEYLEFVAGLWGIDPRTSESSARDLLMSLG 126 G DA DP AK ++AW DE MIYDKLTPLEYLEFVAGLW I+PRT+++ A +LL +LG Sbjct: 68 GVDARKDPAGAKALLAWAPDEAMIYDKLTPLEYLEFVAGLWNINPRTAKAKAEELLATLG 127 Query: 127 LEPHLNERCEGFSKGMRQKVALAGALVHDPRLIILDEPLTGLDALSARHVKGLLQERVRA 186 L RCEGFS+GM+QKVALAGAL+HDP+L+ILDEPLTGLDA +AR VK +LQ RV A Sbjct: 128 LASEARRRCEGFSRGMKQKVALAGALIHDPKLLILDEPLTGLDAAAARLVKDMLQARVDA 187 Query: 187 GCTVIMTTHILEVAERMADRIGVIAAGRLIAEGTLAELREQNGR-NDTTLEDMFIALVDT 245 G TVI+TTHIL+VAERMADRIG+IA GRL+AEGTL ELR + G + TLED+F+ L Sbjct: 188 GGTVILTTHILDVAERMADRIGIIAGGRLLAEGTLDELRSRAGEASGRTLEDVFLQLT-A 246 Query: 246 EAAA 249 EAAA Sbjct: 247 EAAA 250 >TM0793 [V] COG1131 ABC-type multidrug transport system, ATPase component Tma Thermotoga maritima Length = 260 Score = 207 bits (527), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 104/239 (43%), Positives = 153/239 (64%), Gaps = 2/239 (0%) Query: 5 LSALAVRGLTKRF-DRPAVDALDLTIRVGEFYALLGPNGAGKTTTLRMVAGLLRPDAGSV 63 +S + RGLT++F D AVD +DL++R GE Y LGPNGAGKTTT++M+ G+L+P G V Sbjct: 9 ISLIVARGLTRKFGDFTAVDHIDLSVRPGEIYGFLGPNGAGKTTTIKMLTGVLKPTEGEV 68 Query: 64 SILGTDALADPVSAKQVMAWVSDEPMIYDKLTPLEYLEFVAGLWGIDPRTSESSARDLLM 123 ILG + K+ + + DEP IY LT E+L+F+ ++ + + +L Sbjct: 69 EILGMKMSTHEIEIKKSIGVIPDEPKIYSHLTGKEFLDFIIEIYDLKEEEIDKRIAELCE 128 Query: 124 SLGLEPHLNERCEGFSKGMRQKVALAGALVHDPRLIILDEPLTGLDALSARHVKGLLQER 183 + ++ +L +R S GM+QK+ L + P++I LDEP GLDA SAR +K LL++ Sbjct: 129 AFKVD-YLGKRVGEMSHGMKQKLMLVSVFMRKPKVIFLDEPTVGLDAKSARILKLLLRKY 187 Query: 184 VRAGCTVIMTTHILEVAERMADRIGVIAAGRLIAEGTLAELREQNGRNDTTLEDMFIAL 242 G + +TTHILE+AE+M DRIG+I GRLIAEGT+ ELR+ G+ + +LED+F+ L Sbjct: 188 ADEGAAIFLTTHILEIAEKMCDRIGIINKGRLIAEGTMEELRKLAGQKEASLEDLFLQL 246 >CAC0268 [V] COG1131 ABC-type multidrug transport system, ATPase component Cac Clostridium acetobutylicum Length = 258 Score = 196 bits (499), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 84/226 (37%), Positives = 150/226 (66%) Query: 19 RPAVDALDLTIRVGEFYALLGPNGAGKTTTLRMVAGLLRPDAGSVSILGTDALADPVSAK 78 AVD L+ TI GE + LGPNGAGK+TT++M+ G+++ D+G + + G + +P+ AK Sbjct: 29 NKAVDNLNFTINSGEIFGFLGPNGAGKSTTIKMITGIIKADSGEIKVDGLNIKENPIEAK 88 Query: 79 QVMAWVSDEPMIYDKLTPLEYLEFVAGLWGIDPRTSESSARDLLMSLGLEPHLNERCEGF 138 + + +V D P ++ +L +EYL F+A ++ + + L +E L+++ + + Sbjct: 89 RKIGYVPDSPDMFLRLKGIEYLNFMADIYDVTTSDRKERIESLSKYFDMESALDDKIQSY 148 Query: 139 SKGMRQKVALAGALVHDPRLIILDEPLTGLDALSARHVKGLLQERVRAGCTVIMTTHILE 198 S GMRQK+ + GAL+HDP + ILDEP+TGLD ++ ++K ++++ +G TV +TH+LE Sbjct: 149 SHGMRQKIVVMGALIHDPDVWILDEPMTGLDPKASYNLKEMMRKHADSGKTVFFSTHVLE 208 Query: 199 VAERMADRIGVIAAGRLIAEGTLAELREQNGRNDTTLEDMFIALVD 244 VAE++ DRIG+++ G+++ GT+ E++++ ++LE MF+ LV+ Sbjct: 209 VAEKLCDRIGIVSKGKIVFCGTMNEMKQKLQEEGSSLERMFLELVE 254 >PAB1696 [V] COG1131 ABC-type multidrug transport system, ATPase component Pab Pyrococcus abyssi Length = 253 Score = 187 bits (476), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 91/244 (37%), Positives = 151/244 (61%), Gaps = 3/244 (1%) Query: 8 LAVRGLTKRFD-RPAVDALDLTIRVGEFYALLGPNGAGKTTTLRMVAGLLRPDAGSVSIL 66 + V L KRF + + + T++ GE Y LLGPNG+GK+TT+R+++G++ G V + Sbjct: 2 IIVENLRKRFGGKEVLKGISFTVKDGEIYGLLGPNGSGKSTTMRILSGIITDFEGKVIVG 61 Query: 67 GTDALADPVSAKQVMAWVSDEPMIYDKLTPLEYLEFVAGLWGIDPRTSESSARDLLMSLG 126 G + DP+ K+++ +V + P +Y+ LTP E+ FV G+ GI E R L+ + Sbjct: 62 GVEVAKDPLQVKRIVGYVPETPALYESLTPAEFFSFVGGVRGIPKDILEERVRKLVEAFE 121 Query: 127 LEPHLNERCEGFSKGMRQKVALAGALVHDPRLIILDEPLTGLDALSARHVKGLLQERVRA 186 ++ ++N+ S G +QK++L +L+HDP+++ILDE + GLD SAR + LL E Sbjct: 122 IKKYMNQLIGTLSFGTKQKISLISSLLHDPKVLILDEAMNGLDPKSARIFRELLYEFKEE 181 Query: 187 GCTVIMTTHILEVAERMADRIGVIAAGRLIAEGTLAELREQNGRNDTTLEDMFIALVDTE 246 G +++ +TH+L +AE + DR+G+I GR+IAEGT+ EL+E + + LED+F+ L + Sbjct: 182 GKSIVFSTHVLALAELICDRVGIIYQGRIIAEGTVEELKEIS--KEERLEDVFLKLTQAK 239 Query: 247 AAAA 250 A Sbjct: 240 EEIA 243 >PH1230 [V] COG1131 ABC-type multidrug transport system, ATPase component Pho Pyrococcus horikoshii Length = 253 Score = 186 bits (472), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 92/236 (38%), Positives = 147/236 (62%), Gaps = 3/236 (1%) Query: 8 LAVRGLTKRF-DRPAVDALDLTIRVGEFYALLGPNGAGKTTTLRMVAGLLRPDAGSVSIL 66 + V L K+F + + ++ T+ GE Y LLGPNG+GK+TT+R+++G++ G V + Sbjct: 2 IIVENLRKKFGSKEVLKGINFTVNDGEIYGLLGPNGSGKSTTMRILSGIITDFEGKVMVA 61 Query: 67 GTDALADPVSAKQVMAWVSDEPMIYDKLTPLEYLEFVAGLWGIDPRTSESSARDLLMSLG 126 G D DP+ K+++ +V + P +Y+ LTP E+ F+ G+ I E + L+ + G Sbjct: 62 GVDVSRDPMKVKEIVGYVPETPALYESLTPAEFFSFIGGVRRIPQDILEERVKRLVDAFG 121 Query: 127 LEPHLNERCEGFSKGMRQKVALAGALVHDPRLIILDEPLTGLDALSARHVKGLLQERVRA 186 + ++N+ S G +QK++L AL+HDP+++ILDE + GLD SAR + LL E Sbjct: 122 IGKYMNQLIGTLSFGTKQKISLISALLHDPQVLILDEAMNGLDPKSARIFRELLFEFKEE 181 Query: 187 GCTVIMTTHILEVAERMADRIGVIAAGRLIAEGTLAELREQNGRNDTTLEDMFIAL 242 G +++ +THIL +AE M DRIG+I GR++AEGT+ ELRE + LED+F+ L Sbjct: 182 GKSIVFSTHILALAEVMCDRIGIIYEGRIVAEGTIDELREIA--REEKLEDIFLKL 235