BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0073.0001.p (277 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll7705 [L] COG1573 Uracil-DNA glycosylase Mlo Mesorhizobium loti 291 8e-79 BMEI1321 [L] COG1573 Uracil-DNA glycosylase Bme Brucella melitensis 260 2e-69 RP845 [L] COG1573 Uracil-DNA glycosylase Rpr Rickettsia prowazekii 198 9e-51 AGc1810 [L] COG1573 Uracil-DNA glycosylase Atu Agrobacterium tum... 198 1e-50 RC1309 [L] COG1573 Uracil-DNA glycosylase Rco Rickettsia conorii 197 2e-50 >mll7705 [L] COG1573 Uracil-DNA glycosylase Mlo Mesorhizobium loti Length = 291 Score = 291 bits (746), Expect = 8e-79, Method: Compositional matrix adjust. Identities = 162/289 (56%), Positives = 189/289 (65%), Gaps = 16/289 (5%) Query: 1 MMALPPEPTPTLQQLLAFYLEAGVDCALGDAPINRLEEPEPVPAPAAPRPSAALNPLRPP 60 M A P + +LAFY AGVD AL DAP+NR E P P AP P A + P Sbjct: 1 MTAASPNSPTDIADILAFYASAGVDEALEDAPVNRFAEAAPRPVERAPAPVAPPREEKAP 60 Query: 61 PMPSVP--------------RSEITVAPD-AAIASAREAARTAPTLEALRALMENFDGCA 105 P+ P RS + PD A A AR+ A TA TL+ LR M FDGC Sbjct: 61 ERPAAPPGLDASKVPDAPPARSSVAAVPDEAQAALARQLATTATTLDELRQHMAAFDGCN 120 Query: 106 LKHTATRLVFADGNPQARVMFVGEAPGRDEDIEGLPFVGRSGKLLDRMIAAIGLDRSKAY 165 LK TA LVFADGNP A VM VGEAPGRDEDIEGLPFVGRSG+LLDRM+AAIGLDR+ Y Sbjct: 121 LKATAKNLVFADGNPDAAVMLVGEAPGRDEDIEGLPFVGRSGRLLDRMLAAIGLDRTSVY 180 Query: 166 IANVIPWRPPGNRTPTPQETQVCLPFIQRHIELVNPDVLVTLGNPSTQALLGTREGIMRT 225 IANVIPWRPPGNRTPTP ET++C PFI+R IELVNP VLV LG PS + LL T EGI+R Sbjct: 181 IANVIPWRPPGNRTPTPHETEICRPFIERQIELVNPKVLVNLGGPSAKTLLNTSEGILRL 240 Query: 226 RGKWIDYDTGTR-TIRAVATFHPAYLLRSPSYKRLSWQDLRAIAKVLQA 273 RG W + T + I A+ T HPAYLLR+P++K+L+W+D + L+A Sbjct: 241 RGNWRVHTTASGIAIPAMPTLHPAYLLRTPAHKKLAWRDFLEVKAKLRA 289 >BMEI1321 [L] COG1573 Uracil-DNA glycosylase Bme Brucella melitensis Length = 290 Score = 260 bits (665), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 143/276 (51%), Positives = 176/276 (63%), Gaps = 18/276 (6%) Query: 9 TPTLQQLLAFYLEAGVDCALGDAPINRLEEPEPVPAPAAPRPSAAL-----NPLR----- 58 T ++ LL FY EAGVD L + PI+R PAPA R AA NP + Sbjct: 7 TLDMEGLLRFYAEAGVDVPLCETPIDRFAAATH-PAPAQSRMQAAAQQPESNPAQAREER 65 Query: 59 ------PPPMPSVPRSEITVAPDAAIASAREAARTAPTLEALRALMENFDGCALKHTATR 112 P P ++ + + +A IA AREAA A TLE LR + FDGC LK TA Sbjct: 66 ARTVAVPSPSSKPVQAAMDLPDNAQIALAREAASQAETLEELREKLAAFDGCNLKFTAKN 125 Query: 113 LVFADGNPQARVMFVGEAPGRDEDIEGLPFVGRSGKLLDRMIAAIGLDRSKAYIANVIPW 172 L FADG+P + +MF+GEAPGRDED+EGLPFVG+SG+LL+RMI AIGL R + YIAN IPW Sbjct: 126 LCFADGDPSSDIMFIGEAPGRDEDMEGLPFVGKSGQLLNRMIEAIGLKREEVYIANTIPW 185 Query: 173 RPPGNRTPTPQETQVCLPFIQRHIELVNPDVLVTLGNPSTQALLGTREGIMRTRGKWIDY 232 RPPGNR PTP ET++C PFI+R IEL P VLV LG P+ +AL G EGI+R RG W + Sbjct: 186 RPPGNRAPTPLETELCRPFIERQIELAAPKVLVALGGPAGKALTGAAEGILRLRGNWKIH 245 Query: 233 DTGT-RTIRAVATFHPAYLLRSPSYKRLSWQDLRAI 267 T T I + T HPAYLLR+P+ KR +W+D A+ Sbjct: 246 RTPTGMEIPVMPTLHPAYLLRTPAQKRFAWRDFLAV 281 >RP845 [L] COG1573 Uracil-DNA glycosylase Rpr Rickettsia prowazekii Length = 258 Score = 198 bits (504), Expect = 9e-51, Method: Compositional matrix adjust. Identities = 91/196 (46%), Positives = 123/196 (62%), Gaps = 2/196 (1%) Query: 78 IASAREAARTAPTLEALRALMENFDGCALKHTATRLVFADGNPQARVMFVGEAPGRDEDI 137 I +R A A + LR + NF+GC LK AT VF DGNPQA +M +GEAPG ED+ Sbjct: 56 ITLSRSLADKANNIVELRESLLNFNGCELKKFATNTVFGDGNPQANIMLIGEAPGNTEDL 115 Query: 138 EGLPFVGRSGKLLDRMIAAIGLDRSKAYIANVIPWRPPGNRTPTPQETQVCLPFIQRHIE 197 +G+PF G SG LLD M+ AIG+ R+ YI N++ WRPP NR PT +E +C PF+++HI Sbjct: 116 KGIPFCGESGNLLDNMLYAIGISRNNFYITNMVFWRPPANRQPTLEEVDICRPFVEKHIA 175 Query: 198 LVNPDVLVTLGNPSTQALLGTREGIMRTRGKWIDYDTGTRT--IRAVATFHPAYLLRSPS 255 L+NP +L+ +G+ + +LLG I + R ++ Y + I+ A FHPAYLLR P Sbjct: 176 LINPKLLILVGSTAATSLLGKNACITKIRQEYYFYTNKYISTPIQTTAIFHPAYLLRQPM 235 Query: 256 YKRLSWQDLRAIAKVL 271 KR SW DL I + L Sbjct: 236 QKRTSWYDLLKIKEYL 251 >AGc1810 [L] COG1573 Uracil-DNA glycosylase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 296 Score = 198 bits (503), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 110/278 (39%), Positives = 157/278 (56%), Gaps = 22/278 (7%) Query: 12 LQQLLAFYLEAGVDCALGDAPINRLEE---PEPVPAPAAPRPSAALN---------PLRP 59 L LL F+ +AGVD L +AP++R E P+P A P+ P R Sbjct: 12 LAALLHFHADAGVDWMLEEAPVDRFAEFAAARPMPGQDAATPARQAQSPADRRTDAPQRQ 71 Query: 60 PPMPSVP----------RSEITVAPDAAIASAREAARTAPTLEALRALMENFDGCALKHT 109 P S P + + + + A+++AR AA +A +L LR +E F+GC LK++ Sbjct: 72 APGRSAPARGAPAAPAIQQNVAMPDEQAVSAARFAAESARSLGELRTALEGFNGCNLKNS 131 Query: 110 ATRLVFADGNPQARVMFVGEAPGRDEDIEGLPFVGRSGKLLDRMIAAIGLDRSKAYIANV 169 A +F++G+P + +M +G P D+D EG PF G++G+LL+RM+AAIGL+RS I NV Sbjct: 132 ARNTIFSEGDPASAIMVIGPMPDADDDREGTPFAGKTGQLLERMLAAIGLERSAIMIGNV 191 Query: 170 IPWRPPGNRTPTPQETQVCLPFIQRHIELVNPDVLVTLGNPSTQALLGTREGIMRTRGKW 229 +PWRPPGNR PT E +C PFI+R I L P L+ LGN + + G I RG+W Sbjct: 192 VPWRPPGNRPPTQAEMDICRPFIERQIALAEPKHLLLLGNFTARFFFGGTGTIHTLRGQW 251 Query: 230 IDYDTGTRTIRAVATFHPAYLLRSPSYKRLSWQDLRAI 267 D G + A+A+ HP LL +P+ K L+WQDL A Sbjct: 252 RDVAAGHLILPALASLHPQELLNAPASKSLAWQDLLAF 289 >RC1309 [L] COG1573 Uracil-DNA glycosylase Rco Rickettsia conorii Length = 279 Score = 197 bits (502), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 91/197 (46%), Positives = 125/197 (63%), Gaps = 3/197 (1%) Query: 78 IASAREAARTAPTLEALRALMENFDGCALKHTATRLVFADGNPQARVMFVGEAPGRDEDI 137 I AR A A +E L+ + NF+GC LK AT VF DGN +A++M +GEAPG ED+ Sbjct: 76 ITLARSLADKANNIEELKESLLNFNGCELKKFATNTVFGDGNLEAKIMLIGEAPGSTEDL 135 Query: 138 EGLPFVGRSGKLLDRMIAAIGLDR-SKAYIANVIPWRPPGNRTPTPQETQVCLPFIQRHI 196 +G+PF G SG LLD M+ AIG+ R + AYI N + WRPP NR PT +E +C PF+++HI Sbjct: 136 KGIPFYGESGNLLDNMLHAIGISRKNNAYITNTVFWRPPANRQPTFEEVDICRPFVEKHI 195 Query: 197 ELVNPDVLVTLGNPSTQALLGTREGIMRTRGKWIDYDTGTRT--IRAVATFHPAYLLRSP 254 L+NP +++ +G+ + +LLG GI + R ++ Y + I+ A FHPAYLLR P Sbjct: 196 ALINPQLIILVGSTAATSLLGKNSGITKIRQEYYFYTNKYLSAPIQTTAIFHPAYLLRQP 255 Query: 255 SYKRLSWQDLRAIAKVL 271 KR SW DL I + L Sbjct: 256 MQKRTSWYDLLKIKEYL 272