BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0072.0052.p (427 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yybO [GEPR] COG0477 Permeases of the major facilitator superf... 186 1e-46 RSp1614 [GEPR] COG0477 Permeases of the major facilitator superf... 179 1e-44 STM1543 [GEPR] COG0477 Permeases of the major facilitator superf... 176 1e-43 yjiZ [GEPR] COG0477 Permeases of the major facilitator superfami... 170 5e-42 ZyjiZ [GEPR] COG0477 Permeases of the major facilitator superfam... 168 2e-41 >BS_yybO [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 435 Score = 186 bits (472), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 125/398 (31%), Positives = 207/398 (52%), Gaps = 15/398 (3%) Query: 13 AMLCVMYFITYVDRVNIGTAAGEIQKELGLSNTELGLVFSAFAYPYLLFQVIGGWVGDRF 72 ++L + + Y DRV I AA IQ L+ TELG+VFS + Y Y L Q+ G + DRF Sbjct: 25 SLLSGIIILNYFDRVAISVAAPAIQDSFHLTATELGIVFSIYTYSYTLMQLPVGSLLDRF 84 Query: 73 GPRQTLFWCGMIWAAATIMTGFVHGLAALFVARFALGFGEGATFPTATRAMQYWTPANRR 132 G IW+ TI+ F+ G L++ RF +G + FP A++A W P + R Sbjct: 85 GVAWVTRVGMTIWSFLTILLAFLQGKLLLYLFRFLIGLTSASAFPAASKATALWFPPSER 144 Query: 133 GFAQGLTHSFARLGNAITPPVVALLILWLTWRGAFVVLGVVSLIWGIAWVWYFRNEPRDH 192 G A L S A+ N I P+VA L+ WR AF+ +G +++++ I + W + +P H Sbjct: 145 GLANSLFDSAAKFSNVIGAPLVAFLVTTFDWRVAFLTIGCINVLFTI-FFWQYYEQPERH 203 Query: 193 GSITAAELATLPPRPQGERPKVPW--GPLLQRM------WPVTLTYFCYGWCLWLYLNWL 244 I+ +EL + ++P+ GPLL+++ W + + + YG+ L L WL Sbjct: 204 KRISKSELNYIQKHNAITTEQIPYKTGPLLKKLFTNRKVWGLMIGFTGYGYTFNLLLTWL 263 Query: 245 PLFFKNNYSLDLKNSALF-ASGVFFAGVVGDSIGGVISDRILER-TGNVRLARLSVTVVG 302 P FFK+ Y +DL +S LF A + + G ++GG + D +++ N ++ R +V +VG Sbjct: 264 PTFFKHTYGMDLMSSGLFTAVPWLISTISGIAVGGWLVDYFIKKGYPNTKVYR-TVIIVG 322 Query: 303 FAGALLSLMPILFVHDITVVALCLSAGFFCAELVIGPMWSIPMDIA--AKYSGTAAGIMN 360 + L IL ++ITV +C+S G WSI ++A S ++ + Sbjct: 323 MSFGFFFLGSIL-TNNITVAIICISIGLAGISATAPVGWSISAELAPIGSVSMLSSMVNL 381 Query: 361 TGSAFAAIVSPLVAGFVIDATGNWYLPFLMSMGLLLVG 398 + F I++ + G++ D TG++ L FL++ +LL+G Sbjct: 382 ANNLFGGIIAASLTGYLFDVTGSFTLSFLVAGFVLLLG 419 >RSp1614 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 448 Score = 179 bits (453), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 118/401 (29%), Positives = 190/401 (47%), Gaps = 11/401 (2%) Query: 4 RFKATHVVLAMLCVMYFITYVDRVNIGTAAGEIQKELGLSNTELGLVFSAFAYPYLLFQV 63 R K +V ++ I Y+DR + AA IQKE LS E+G+V SAF + Y L Q+ Sbjct: 10 RSKVRWLVAGLMWAAIAINYIDRTVLSAAAPHIQKEFHLSAVEMGVVMSAFFWSYALLQL 69 Query: 64 IGGWVGDRFGPRQTLFWCGMIWAAATIMTGFVHGLAALFVARFALGFGEGATFPTATRAM 123 G + DRFG ++ L + + W+ AT +TG G +L R ALG GE +P+ Sbjct: 70 PAGILADRFGQKKVLGFAVLWWSLATAVTGLATGFKSLVGLRVALGVGEAGAYPSNAGIT 129 Query: 124 QYWTPANRRGFAQGLTHSFARLGNAITPPVVALLILWLTWRGAFVVLGVVSLIWGIAWVW 183 W P R + S ++LG+AI P++A L++ W+ F V G + ++W + W Sbjct: 130 SRWFPKQERATVAAIFDSGSKLGSAIALPLIAWLLVTFDWKITFTVAGSLGIVWCVVWAL 189 Query: 184 YFRNEPRDHGSITAAELAT----LPPRPQGERPKVPWGPLL--QRMWPVTLTYFCYGWCL 237 FR+ P +H + AAELA LPP + P +PW LL + +W + + +F + Sbjct: 190 VFRDSPAEHEGVNAAELAHIQKGLPPARGADAPAMPWTKLLTHRNVWAMCIGFFMINYNS 249 Query: 238 WLYLNWLPLFFKNNYSLDLKNSALFASGVFFAGVVGDSIGGVISDRILERTGNVRL--AR 295 + ++ WLP + + L AS F + + G SDR+ +G + L R Sbjct: 250 YFFITWLPTYLVKERGMGLMEMGFMASLPLFVSMFVEVFAGWASDRVYA-SGRLSLTATR 308 Query: 296 LSVTVVGFAGALLSLMPILFVHDITVVALCLSAGFFCAELVIGPMWSIPMDIAAKYS-GT 354 V+G A S+ F V + L + +W++P D+A + Sbjct: 309 KLFLVIGLVMA-SSIGLAAFAQSAVVAVILLCIAKSGTTVAASQVWALPADVAPGNTVSM 367 Query: 355 AAGIMNTGSAFAAIVSPLVAGFVIDATGNWYLPFLMSMGLL 395 AG+ N+ S +V P+V G ++ ATG++ + S L+ Sbjct: 368 VAGLQNSVSNMGGVVGPIVTGAIVGATGSFIPALVFSAALI 408 >STM1543 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 428 Score = 176 bits (445), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 113/412 (27%), Positives = 194/412 (47%), Gaps = 10/412 (2%) Query: 10 VVLAMLCVMYFITYVDRVNIGTAAGEIQKELGLSNTELGLVFSAFAYPYLLFQVIGGWVG 69 +++ +L ++Y + Y+DR + A I+KELG + E+G++FSAF Y LF IGGW Sbjct: 9 LIVFLLFIVYMLNYMDRSALSITAPLIEKELGFNAAEMGMIFSAFFIGYALFNFIGGWAS 68 Query: 70 DRFGPRQTLFWCGMIWAAATIMTGFVHGLAALFVARFALGFGEGATFPTATRAMQYWTPA 129 D+ GP+ ++W+ +TG V GL + + R G EG + + W Sbjct: 69 DKVGPKTVFLIAALLWSVFCGLTGLVTGLWTMLIVRVLFGMAEGPVSAAGNKIINNWISR 128 Query: 130 NRRGFAQGLTHSFARLGNAITPPVVALLILWLTWRGAFVVLGVVSLIWGIAWVWYFRNEP 189 A G+ + + LG A++ P+V LL L L WR AF ++ + L+W + W + ++P Sbjct: 129 KESATAIGIFSAGSPLGGAVSGPIVGLLALSLGWRPAFGIIFLFGLVWVLLWYFIVSDKP 188 Query: 190 RDHGSITAAELATLPPRP-----QGERPKVPWGPLLQR--MWPVTLTYFCYGWCLWLYLN 242 + E R G +++ +W TL +F Y + L+ +L Sbjct: 189 TMSKRLAPEERIDFENHEDVILSDDGRATPSLGYYMKQPMVWATTLAFFSYNYILFFFLT 248 Query: 243 WLPLFFKNNYSLDLKNSALFASGVFFAGVVGDSIGGVISDRILERTGNVRLARLSVTVVG 302 W P + ++ LD+K ++ + G +G +GGV SD I TGN L+R + V Sbjct: 249 WFPSYLNHSLHLDIKEISIATVIPWVIGAIGMVLGGVCSDVIYRITGNALLSRRLILGVC 308 Query: 303 FAGALLSLMPILFVHDITVVALCLSAGFFCAELVIGPM-WSIPMDIAAKYS-GTAAGIMN 360 AGA + + V I +S F L GP+ W++ D+ K G+ G M+ Sbjct: 309 LAGAAVCVAVSGTVSTIGSAITLMSVSLFLLYLT-GPIYWAVIQDVVHKDKVGSVGGAMH 367 Query: 361 TGSAFAAIVSPLVAGFVIDATGNWYLPFLMSMGLLLVGGFSAFLMHPERPFE 412 + + I+ PLV GF++ +G + F ++ + +V F+ + F+ Sbjct: 368 GLANISGIIGPLVTGFIVQFSGKYDYAFYLAGAIAIVSSLLVFVFVKSKGFK 419 >yjiZ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 453 Score = 170 bits (431), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 112/401 (27%), Positives = 192/401 (47%), Gaps = 12/401 (2%) Query: 21 ITYVDRVNIGTAAGEIQKELGLSNTELGLVFSAFAYPYLLFQVIGGWVGDRFGPRQTLFW 80 I Y+DR ++ A I++ELGLS TE+G + S F+ Y + Q+ G + DR GPR L Sbjct: 53 INYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGL 112 Query: 81 CGMIWAAATIMTGFVHGLAALFVARFALGFGEGATFPTATRAMQYWTPANRRGFAQGLTH 140 W+ M+G VH + R +G GE P + + W RG G + Sbjct: 113 GMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFN 172 Query: 141 SFARLGNAITPPVVALLILWLTWRGAFVVLGVVSLIWGIAWVWYFRNEPRDHGSITAAEL 200 + + +G A++PP++A ++L + WRG F+ +GV+ + I W +RN R+H +TA E Sbjct: 173 AASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRN--REHVELTAVEQ 230 Query: 201 ATLPPRPQGERPK----VPWGPLLQR--MWPVTLTYFCYGWCLWLYLNWLPLFFKNNYSL 254 A L R W L + MW + L + + WLYL WLP + + Y+L Sbjct: 231 AYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNL 290 Query: 255 DLKNSALFASGVFFAGVVGDSIGGVISDRILE-RTGNVRLARLSVTVVGFAGALLSLMPI 313 DLK++ L A+ F G G + G ++D +++ ++ ++ + F A +L+ Sbjct: 291 DLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSAAFTLIVP 350 Query: 314 LFVHDITVVALCLSAGFFCAELVIGPMWS-IPMDIAAKYSGTAAGIMNTGSAFAAIVSPL 372 +T V L + FC W I + +A++ + + I N S A +P+ Sbjct: 351 QATTSMTAV-LLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFASFICASFAPI 409 Query: 373 VAGFVIDATGNWYLPFLMSMGLLLVGGFSAFLMHPERPFEE 413 + GF++D T ++ L ++ G + G A++ +P + Sbjct: 410 ITGFIVDTTHSFRLALIIC-GCVTAAGALAYIFLVRQPIND 449 >ZyjiZ [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 453 Score = 168 bits (426), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 114/403 (28%), Positives = 191/403 (47%), Gaps = 16/403 (3%) Query: 21 ITYVDRVNIGTAAGEIQKELGLSNTELGLVFSAFAYPYLLFQVIGGWVGDRFGPRQTLFW 80 I Y+DR ++ A I++ELGLS TE+G + S F+ Y + Q+ G + DR GPR L Sbjct: 53 INYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGL 112 Query: 81 CGMIWAAATIMTGFVHGLAALFVARFALGFGEGATFPTATRAMQYWTPANRRGFAQGLTH 140 W+ M+G VH + R +G GE P + + W RG G + Sbjct: 113 GMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFN 172 Query: 141 SFARLGNAITPPVVALLILWLTWRGAFVVLGVVSLIWGIAWVWYFRNEPRDHGSITAAEL 200 + + +G A++PP++A ++L + WRG F+ +GV+ + I W +RN R+H +TA E Sbjct: 173 AASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRN--REHVELTAVEQ 230 Query: 201 ATLPPRPQGERPK----VPWGPLLQR--MWPVTLTYFCYGWCLWLYLNWLPLFFKNNYSL 254 A L R W L + MW + L + + WLYL WLP + + Y+L Sbjct: 231 AYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNL 290 Query: 255 DLKNSALFASGVFFAGVVGDSIGGVISDRILERTGNVRLARLSVTVVGFAGALLSLMPIL 314 DLK++ L A+ F G G + G ++D ++ + G + + ++ AG S L Sbjct: 291 DLKSTGLMAAIPFLFGAAGMLVNGYVTDWLV-KGGMAPIKSRKICII--AGMFCSAAFTL 347 Query: 315 FVHDIT---VVALCLSAGFFCAELVIGPMWS-IPMDIAAKYSGTAAGIMNTGSAFAAIVS 370 V T + L + FC W I + +A++ + + I N S A + Sbjct: 348 IVPQATTSMMAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFASFICASFA 407 Query: 371 PLVAGFVIDATGNWYLPFLMSMGLLLVGGFSAFLMHPERPFEE 413 P++ GF++D T ++ L ++ G + G A++ +P + Sbjct: 408 PIITGFIVDTTHSFRLALIIC-GCVTAAGALAYIFLVRQPLND 449