BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0072.0024.p (301 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value rfbA [M] COG1209 dTDP-glucose pyrophosphorylase Eco Escherichia ... 385 e-107 STM2095 [M] COG1209 dTDP-glucose pyrophosphorylase Sty Salmonell... 380 e-105 SPy0933 [M] COG1209 dTDP-glucose pyrophosphorylase Spy Streptoco... 380 e-105 CC1141 Non COG 380 e-105 L197041 [M] COG1209 dTDP-glucose pyrophosphorylase Lla Lactococc... 380 e-105 >rfbA [M] COG1209 dTDP-glucose pyrophosphorylase Eco Escherichia coli K12 Length = 293 Score = 385 bits (988), Expect = e-107, Method: Compositional matrix adjust. Identities = 179/286 (62%), Positives = 226/286 (79%), Gaps = 2/286 (0%) Query: 2 KGIILAGGTGSRX--VTTVVSKQLLPVFDKPMIYYPLSTLMLGGIRDILIISTPQDKPLF 59 KGIILAGG+G+R VT VSKQLLP++DKPMIYYPLSTLML GIRDILIISTPQD P F Sbjct: 5 KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64 Query: 60 QRLLGDGSEMGVRFAYATQETPRGLADAFIVGRDFIGDDSVALVLGDNIFYGHGLPSMLS 119 Q+LLGDGS+ G+ Y Q +P GLA AFI+G +FIG D ALVLGDNIFYGH LP ++ Sbjct: 65 QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGGDDCALVLGDNIFYGHDLPKLME 124 Query: 120 SASIRKKGATVFGYVVNAPEQYGVIELDGTGRALSIEEKPKRPKSNVAVTGLYFYDNDVV 179 +A ++ GATVF Y VN PE+YGV+E D G A+S+EEKP PKSN AVTGLYFYDNDVV Sbjct: 125 AAVNKESGATVFAYHVNDPERYGVVEFDKNGTAISLEEKPLEPKSNYAVTGLYFYDNDVV 184 Query: 180 DIAAGIRPSPRGEIEITDVNKAYLERGDLYVEVLGRGFAWLDTGTHSSLVEASHFVQILE 239 +A ++PS RGE+EITD+N+ YLE+G L V ++GRG+AWLDTGTH SL+EAS+F+ +E Sbjct: 185 QMAKNLKPSARGELEITDINRIYLEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATIE 244 Query: 240 QRQGLRIACPEEIALRQGYISLEAFARVAQKTAKSSYGEYLLSVYR 285 +RQGL+++CPEEIA R+G+I +E ++A K++YG+YL + + Sbjct: 245 ERQGLKVSCPEEIAFRKGFIDVEQVRKLAVPLIKNNYGQYLYKMTK 290 >STM2095 [M] COG1209 dTDP-glucose pyrophosphorylase Sty Salmonella typhimurium LT2 Length = 292 Score = 380 bits (977), Expect = e-105, Method: Compositional matrix adjust. Identities = 176/286 (61%), Positives = 226/286 (79%), Gaps = 2/286 (0%) Query: 2 KGIILAGGTGSRX--VTTVVSKQLLPVFDKPMIYYPLSTLMLGGIRDILIISTPQDKPLF 59 KGIILAGG+G+R VT VSKQLLP++DKPMIYYPLSTLML GIRDILIISTPQD P F Sbjct: 5 KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64 Query: 60 QRLLGDGSEMGVRFAYATQETPRGLADAFIVGRDFIGDDSVALVLGDNIFYGHGLPSMLS 119 Q+LLGDGS+ G+ Y Q +P GLA AFI+G +FIG D ALVLGDNIFYGH LP ++ Sbjct: 65 QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGHDDCALVLGDNIFYGHDLPKLME 124 Query: 120 SASIRKKGATVFGYVVNAPEQYGVIELDGTGRALSIEEKPKRPKSNVAVTGLYFYDNDVV 179 +A ++ GATVF Y VN PE+YGV+E D G A+S+EEKP +PKSN AVTGLYFYDN VV Sbjct: 125 AAVNKESGATVFAYHVNDPERYGVVEFDQKGTAVSLEEKPLQPKSNYAVTGLYFYDNSVV 184 Query: 180 DIAAGIRPSPRGEIEITDVNKAYLERGDLYVEVLGRGFAWLDTGTHSSLVEASHFVQILE 239 ++A ++PS RGE+EITD+N+ Y+E+G L V ++GRG+AWLDTGTH SL+EAS+F+ +E Sbjct: 185 EMAKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATIE 244 Query: 240 QRQGLRIACPEEIALRQGYISLEAFARVAQKTAKSSYGEYLLSVYR 285 +RQGL+++CPEEIA R+ +I+ + +A +K+ YG+YLL + + Sbjct: 245 ERQGLKVSCPEEIAFRKNFINAQQVIELAGPLSKNDYGKYLLKMVK 290 >SPy0933 [M] COG1209 dTDP-glucose pyrophosphorylase Spy Streptococcus pyogenes M1 GAS Length = 289 Score = 380 bits (975), Expect = e-105, Method: Compositional matrix adjust. Identities = 180/285 (63%), Positives = 227/285 (79%), Gaps = 2/285 (0%) Query: 1 MKGIILAGGTGSRX--VTTVVSKQLLPVFDKPMIYYPLSTLMLGGIRDILIISTPQDKPL 58 MKGIILAGG+G+R +T SKQL+P++DKPMIYYPLSTLML GI+D+LIISTPQD P Sbjct: 1 MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLAGIKDVLIISTPQDLPR 60 Query: 59 FQRLLGDGSEMGVRFAYATQETPRGLADAFIVGRDFIGDDSVALVLGDNIFYGHGLPSML 118 F+ LLGDGSE G+ +Y Q +P GLA AFI+G +FIGDD VAL+LGDNI++G+GL ML Sbjct: 61 FEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRVALILGDNIYHGNGLTKML 120 Query: 119 SSASIRKKGATVFGYVVNAPEQYGVIELDGTGRALSIEEKPKRPKSNVAVTGLYFYDNDV 178 A+ ++KGATVFGY V PE++GV+E D A+SIEEKP+ PKS+ AVTGLYFYDNDV Sbjct: 121 QKAAAKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEKPEVPKSHFAVTGLYFYDNDV 180 Query: 179 VDIAAGIRPSPRGEIEITDVNKAYLERGDLYVEVLGRGFAWLDTGTHSSLVEASHFVQIL 238 V+IA I+PS RGE+EITDVNKAYLERGDL VE++GRGFAWLDTGTH SL+EA+ +++ + Sbjct: 181 VEIAKNIKPSARGELEITDVNKAYLERGDLSVELMGRGFAWLDTGTHESLLEAAQYIETV 240 Query: 239 EQRQGLRIACPEEIALRQGYISLEAFARVAQKTAKSSYGEYLLSV 283 ++ Q ++A EEIA R GYIS E ++AQ K+ YG+YLL + Sbjct: 241 QRLQNAQVANLEEIAYRMGYISKEDVHKLAQSLKKNEYGQYLLRL 285 >CC1141 Non COG Length = 289 Score = 380 bits (975), Expect = e-105, Method: Compositional matrix adjust. Identities = 183/285 (64%), Positives = 226/285 (79%), Gaps = 2/285 (0%) Query: 1 MKGIILAGGTGSRX--VTTVVSKQLLPVFDKPMIYYPLSTLMLGGIRDILIISTPQDKPL 58 MKGIILAGG+G+R +T V SKQL+PV+DKPMIYYPLSTLML GIR+ILIISTP+D P Sbjct: 1 MKGIILAGGSGTRLHPMTLVTSKQLMPVYDKPMIYYPLSTLMLAGIREILIISTPRDTPN 60 Query: 59 FQRLLGDGSEMGVRFAYATQETPRGLADAFIVGRDFIGDDSVALVLGDNIFYGHGLPSML 118 FQ LLGDGS+ G+ YA Q +P GLA A+++G DF+G D AL+LGDNI++GHG+ ++ Sbjct: 61 FQALLGDGSQWGLDIQYAVQPSPDGLAQAYVIGADFVGRDPSALILGDNIYFGHGITNLF 120 Query: 119 SSASIRKKGATVFGYVVNAPEQYGVIELDGTGRALSIEEKPKRPKSNVAVTGLYFYDNDV 178 + A R KGATVF Y VN PE+YGV+E D ALSIEEKPK PKSN AVTGLYFYD DV Sbjct: 121 TRAMARPKGATVFAYHVNDPERYGVVEFDKQMTALSIEEKPKVPKSNWAVTGLYFYDGDV 180 Query: 179 VDIAAGIRPSPRGEIEITDVNKAYLERGDLYVEVLGRGFAWLDTGTHSSLVEASHFVQIL 238 VDIA ++PS RGE+EITDVN+AYLERGDL VE++GRG+AWLDTGT SL+EA+ FV++L Sbjct: 181 VDIARDLKPSARGELEITDVNRAYLERGDLSVELMGRGYAWLDTGTPDSLLEAAEFVRVL 240 Query: 239 EQRQGLRIACPEEIALRQGYISLEAFARVAQKTAKSSYGEYLLSV 283 E+RQG +IACPEE+A ++G+I R+A KS+YG YL +V Sbjct: 241 EKRQGFKIACPEEVAYQKGFIDAAQVERLADALGKSAYGSYLRTV 285 >L197041 [M] COG1209 dTDP-glucose pyrophosphorylase Lla Lactococcus lactis Length = 289 Score = 380 bits (975), Expect = e-105, Method: Compositional matrix adjust. Identities = 179/285 (62%), Positives = 227/285 (79%), Gaps = 2/285 (0%) Query: 1 MKGIILAGGTGSRX--VTTVVSKQLLPVFDKPMIYYPLSTLMLGGIRDILIISTPQDKPL 58 MKGIILAGG+G+R +T SKQL+P++DKPMIYYPLSTLML GI+DILIISTP D P Sbjct: 1 MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLAGIKDILIISTPTDTPR 60 Query: 59 FQRLLGDGSEMGVRFAYATQETPRGLADAFIVGRDFIGDDSVALVLGDNIFYGHGLPSML 118 F+ LL DGSE G+ YA Q +P GLA AFI+G +FIGDDSVAL+LGDNI++G G+ ML Sbjct: 61 FKELLQDGSEFGINLQYAVQPSPDGLAQAFIIGEEFIGDDSVALILGDNIYHGPGMSKML 120 Query: 119 SSASIRKKGATVFGYVVNAPEQYGVIELDGTGRALSIEEKPKRPKSNVAVTGLYFYDNDV 178 +A+ ++KGATVFGY V PE++GV+E D A+SIEEKP+ PKSN AVTGLYFYDNDV Sbjct: 121 QNAAAKEKGATVFGYHVPDPERFGVVEFDENMNAVSIEEKPEEPKSNYAVTGLYFYDNDV 180 Query: 179 VDIAAGIRPSPRGEIEITDVNKAYLERGDLYVEVLGRGFAWLDTGTHSSLVEASHFVQIL 238 ++IA I PSPRGE+EITDVNKAYLERGDL VE++GRGFAWLDTGTH SL+EA+ +++ + Sbjct: 181 IEIAKNIEPSPRGELEITDVNKAYLERGDLSVELMGRGFAWLDTGTHESLLEAAQYIETV 240 Query: 239 EQRQGLRIACPEEIALRQGYISLEAFARVAQKTAKSSYGEYLLSV 283 ++ Q +++A EEIA R GYI+ + ++AQ K+ YG+YLL + Sbjct: 241 QRMQNMQVANLEEIAYRMGYITADDVLKLAQPLKKNEYGQYLLRL 285