BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0070.0037.p         (216 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SA2259 [R] COG2220 Predicted Zn-dependent hydrolases of the beta...    62   6e-10
BS_yddR [R] COG2220 Predicted Zn-dependent hydrolases of the bet...    62   6e-10

>SA2259 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase
           fold Sau Staphylococcus aureus N315
          Length = 255

 Score = 62.4 bits (150), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 52/193 (26%), Positives = 87/193 (45%), Gaps = 9/193 (4%)

Query: 16  VGAIDAVLLSHDQHSDNLDHSGRDFL-KSAKRVLTTEAGARRLGGNAEGFAPWASTELQK 74
           +  ID V+L+H  H D+ D    + L K  K     E  A  +     GF   +      
Sbjct: 58  INDIDLVILTH-LHIDHFDPKAIEVLPKDIKIYAQNEEDASEV--ERYGFTNVSVFNDVT 114

Query: 75  GGRTLTITATPARHGPAGIEPLSGDVIGFVVEPAKPGRPVYVSGDTTWFDGVAEVARRFD 134
               + +  T A+HG   I  ++G V G +++ ++    +Y++ DT WF+GV +  + + 
Sbjct: 115 HIGEIELIKTDAQHGHGEILKMTGHVHGMILKHSEEPT-LYLAADTVWFEGVEKALKTYQ 173

Query: 135 CGVVLPFAGAAQ--TRGPFHLTMDTNDAIETARAFADAVIVPVHTDGWAHFRQSASDLRA 192
             VV+   GA Q    GP  L MD +D ++ A     A IV VH +   H+  S  +L  
Sbjct: 174 PDVVVLNGGANQFFEGGP--LVMDEHDVLKVANTLPLAQIVVVHMEAVNHWHLSRKELNE 231

Query: 193 SFDTLGFGRRLRI 205
             ++   G R+ +
Sbjct: 232 FINSNDLGNRVVV 244


>BS_yddR [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase
           fold Bsu Bacillus subtilis
          Length = 254

 Score = 62.4 bits (150), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 51/194 (26%), Positives = 85/194 (43%), Gaps = 8/194 (4%)

Query: 19  IDAVLLSHDQHSDNLDHSGRDFL-KSAKRVLTTEAGARRLGGNAEGFAPWASTELQKGGR 77
           +DAV+++H  H D+ D   ++ L K+ K  +  EA A+ +   A GF             
Sbjct: 61  VDAVIVTH-LHLDHFDDVAKNVLPKNIKMFVQNEADAKEV--KASGFKNVEVLHQDTVFE 117

Query: 78  TLTITATPARHGP-AGIEPLSGDVIGFVVE-PAKPGRPVYVSGDTTWFDGVAEVARRFDC 135
            + +  T   HG    +  L GDV G V + P++  + +YV+GDT W+D + +       
Sbjct: 118 GIQLVKTKGEHGRGEELLNLMGDVCGLVFKHPSE--KVLYVAGDTVWYDAIEDEIHTHQP 175

Query: 136 GVVLPFAGAAQTRGPFHLTMDTNDAIETARAFADAVIVPVHTDGWAHFRQSASDLRASFD 195
            +++   G  Q      L M   D  E  +A   A I+ VH +   H+  S  +L+    
Sbjct: 176 EIIVVNGGDNQRLDLGSLIMGKEDIYEVHKAAPHAKIISVHMEAVNHWTLSREELKNFSK 235

Query: 196 TLGFGRRLRILEPG 209
             GF   + + E G
Sbjct: 236 EKGFSSNILVPEDG 249