BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0070.0021.p         (200 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CC2147 [CHR] COG1052 Lactate dehydrogenase and related dehydroge...    83   3e-16
SMa0085 [CHR] COG1052 Lactate dehydrogenase and related dehydrog...    82   1e-15
SMa0510 [CHR] COG1052 Lactate dehydrogenase and related dehydrog...    75   7e-14
AGl723 [CHR] COG1052 Lactate dehydrogenase and related dehydroge...    74   2e-13
mlr5162 [CHR] COG1052 Lactate dehydrogenase and related dehydrog...    70   3e-12

>CC2147 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Ccr
           Caulobacter vibrioides
          Length = 319

 Score = 83.2 bits (204), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 52/143 (36%), Positives = 74/143 (51%), Gaps = 15/143 (10%)

Query: 1   MPDKVLVYSRFPKAQLIRFGERYELLNAAGKRVDEAFPKTELAEIRAMITAGGTALGTEA 60
           MP + L+   +   +L  + +R   L   G+             IRA++ AG  AL  + 
Sbjct: 19  MPLQPLLEGAYIVHRLWDYPDRMAFLEGPGQ------------SIRAIVHAGEMALSRDM 66

Query: 61  MDMLPKLGAIVCYGTGYDGVDLAAAAKRGIAVGHSPGANAASVADTAVTLMLASVRRLLV 120
           +  +P+LG I C   GYDGVD+      GIAV HS G NAA VAD AV L+LA+ R ++ 
Sbjct: 67  LAEMPRLGLIACVSVGYDGVDVPWCKAHGIAVTHSTGLNAADVADHAVGLVLAAWRGIVE 126

Query: 121 ADNYVRSGDWAGAK---PSPMMR 140
            D  +R G W+ A+   P P +R
Sbjct: 127 GDQRLRGGHWSHAERMAPRPGLR 149


>SMa0085 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Sme
           Sinorhizobium meliloti
          Length = 317

 Score = 81.6 bits (200), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 57/139 (41%), Positives = 70/139 (50%), Gaps = 6/139 (4%)

Query: 2   PDKVLVYSRFPKA--QLIRFGERYELLNAAGKRVDEAFPKTELAEIRAMITAGGTALGTE 59
           PD +LV    P    +L R    + L  AA +   EA     L  IRA+ T GG  L  E
Sbjct: 8   PDLLLVEPMMPFVMDELQRNYSVHRLYQAADRPALEA----ALPSIRAVATGGGAGLSNE 63

Query: 60  AMDMLPKLGAIVCYGTGYDGVDLAAAAKRGIAVGHSPGANAASVADTAVTLMLASVRRLL 119
            M+ LP LG I   G G D VDLA A +R I V  +PG  A  VAD  + LMLA +RR+ 
Sbjct: 64  WMEKLPSLGIIAINGVGTDKVDLARARRRNIDVTTTPGVLADDVADLGIALMLAVLRRVG 123

Query: 120 VADNYVRSGDWAGAKPSPM 138
             D  VR G WA  +  P+
Sbjct: 124 DGDRLVREGRWAAGEQLPL 142


>SMa0510 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Sme
           Sinorhizobium meliloti
          Length = 315

 Score = 75.5 bits (184), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 43/105 (40%), Positives = 57/105 (54%)

Query: 36  AFPKTELAEIRAMITAGGTALGTEAMDMLPKLGAIVCYGTGYDGVDLAAAAKRGIAVGHS 95
           AF     A IR + T G        ++ LP+L  I  YG GYD VDLAAA +RGI V ++
Sbjct: 37  AFLAEHGAAIRGIATRGELGANWAMIEALPRLEIISVYGVGYDAVDLAAARERGIRVTNT 96

Query: 96  PGANAASVADTAVTLMLASVRRLLVADNYVRSGDWAGAKPSPMMR 140
           P      VAD  V +MLA  R ++  + +V+SGDWA     P+ R
Sbjct: 97  PDVLTKDVADLGVAMMLAHARGMIGGETWVKSGDWAKKGLYPLKR 141


>AGl723 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Atu
           Agrobacterium tumefaciens strain C58 (Cereon)
          Length = 320

 Score = 73.9 bits (180), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 35/75 (46%), Positives = 46/75 (61%)

Query: 61  MDMLPKLGAIVCYGTGYDGVDLAAAAKRGIAVGHSPGANAASVADTAVTLMLASVRRLLV 120
           +D LPKL  I  +G GYDGVD   AA RGI V ++P      VADT + L++ +VRRL  
Sbjct: 61  IDALPKLEIIANFGVGYDGVDAKHAATRGIVVTNTPDVLNDEVADTTIALLINTVRRLYQ 120

Query: 121 ADNYVRSGDWAGAKP 135
           A+ ++R G W G  P
Sbjct: 121 AETWLRDGKWVGEGP 135


>mlr5162 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases Mlo
           Mesorhizobium loti
          Length = 327

 Score = 70.1 bits (170), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 41/128 (32%), Positives = 64/128 (50%), Gaps = 11/128 (8%)

Query: 24  ELLNAAGKRVDEAFPKTELA---------EIRAMITAGGTALGTEA--MDMLPKLGAIVC 72
           +  + A +R+D  F +  +          E+R M+    +  G  A  MD LP L  I  
Sbjct: 17  DFSDHAVRRIDRTFKQVSIERADPALVTDEMRRMVRGIASFAGISAAMMDALPNLELIAS 76

Query: 73  YGTGYDGVDLAAAAKRGIAVGHSPGANAASVADTAVTLMLASVRRLLVADNYVRSGDWAG 132
           +G GYD VD+  AA + I V ++P      VADTA+ L++ ++R L  A+N++R G W  
Sbjct: 77  FGVGYDSVDVGHAAAKNIMVTNTPDVLTEEVADTAIGLLINTIRDLPRAENWLRDGSWVR 136

Query: 133 AKPSPMMR 140
               P+ R
Sbjct: 137 KGNYPLSR 144