BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0067.0003.p (279 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc01429 [R] COG0656 Aldo/keto reductases, related to diketogulo... 262 5e-70 AGc3682 [R] COG0656 Aldo/keto reductases, related to diketogulon... 256 5e-68 mlr5327 [R] COG0656 Aldo/keto reductases, related to diketogulon... 254 2e-67 STM1288 [R] COG0656 Aldo/keto reductases, related to diketogulon... 252 7e-67 yeaE [R] COG0656 Aldo/keto reductases, related to diketogulonate... 248 1e-65 >SMc01429 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Sme Sinorhizobium meliloti Length = 281 Score = 262 bits (670), Expect = 5e-70, Method: Compositional matrix adjust. Identities = 144/272 (52%), Positives = 178/272 (65%), Gaps = 10/272 (3%) Query: 1 VQTKKFGDSGPQVSVIGQGTWYLDRGDRKAA--VAALKRGIDAGMTHIDTAEMYGD--AE 56 + T F D G +V +GQGTW + K A V +L+ G+D GMT IDTAEMYGD AE Sbjct: 5 IPTIAFPD-GRKVPALGQGTWRMGENRAKTADEVRSLQTGLDLGMTLIDTAEMYGDGAAE 63 Query: 57 LVIADAMSGRRDELFLVSKVLPSNASRRGTITACERSLKRLKTDRLDCYLLHWRGTTPLA 116 ++ +A+ GRRDE F+VSKVLPSNASR GT+ ACERSL+ L D +D YLLHWRG PLA Sbjct: 64 RIVGEAIKGRRDEAFVVSKVLPSNASRAGTVAACERSLRNLGIDCVDLYLLHWRGGYPLA 123 Query: 117 ETVAAFDELIAAGKIRAWGVSNFDTEDLDELLDVAGEGTIACNQVLYHLQERAIEHAVIP 176 ETVAAF+EL AGKIRAWGVSNFD +D++EL V G +A NQVLY+L R IE ++P Sbjct: 124 ETVAAFEELKKAGKIRAWGVSNFDVDDMEELSAVPDGGNVAANQVLYNLARRGIEFDLLP 183 Query: 177 WCEQHGVAVVAYSPFGHNDFPAPSSKAGTVLQSIAQAHKATPRQVALSFLTRLPSVLAIP 236 C GV V+AYSP + L IA+AH+ATP QVAL+FL V++IP Sbjct: 184 RCRAQGVPVMAYSPLDEGRLLHDAD-----LIHIAKAHQATPAQVALAFLKTCSGVISIP 238 Query: 237 KASNADHAAENAAAGKLKLSAEELAALDAAFP 268 K + + A EN A + L+ E LA LD FP Sbjct: 239 KTGSPERARENRDAMDIHLTTENLAELDRHFP 270 >AGc3682 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 281 Score = 256 bits (653), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 136/280 (48%), Positives = 182/280 (65%), Gaps = 19/280 (6%) Query: 9 SGPQVSVIGQGTWYL--DRGDRKAAVAALKRGIDAGMTHIDTAEMYGD--AELVIADAMS 64 SG +V +G GTW + R + ++++ ID GMT +DTAEMY D +E V+ A++ Sbjct: 12 SGNEVPALGLGTWNMGETRSSADDEIESIRKAIDLGMTLVDTAEMYADGRSEEVVGTAIA 71 Query: 65 GRRDELFLVSKVLPSNASRRGTITACERSLKRLKTDRLDCYLLHWRGTTPLAETVAAFDE 124 GRRDE+FLVSKV P NAS RGT ACERSL RL TD +D YLLHWRG PL ETVAAF+ Sbjct: 72 GRRDEVFLVSKVYPWNASARGTAEACERSLARLGTDHIDLYLLHWRGEHPLGETVAAFER 131 Query: 125 LIAAGKIRAWGVSNFDTEDLDELLDVAGEGTIACNQVLYHLQERAIEHAVIPWCEQHGVA 184 L + GKI WGVSNFDT+D++EL V A NQVLY+L R E +++PWC++HGV Sbjct: 132 LKSDGKIGNWGVSNFDTDDMEELFTVPEGKNCAANQVLYNLSRRGPEFSLLPWCQEHGVP 191 Query: 185 VVAYSPFGHNDFPAPSSKAGTVLQS-----IAQAHKATPRQVALSFLTRLPSVLAIPKAS 239 ++AYSP + G +L++ IA+A++ATP Q+AL+FL V+AIPK++ Sbjct: 192 LMAYSPI----------EQGRILKNHELIRIAKAYQATPAQLALAFLLDRDGVIAIPKSA 241 Query: 240 NADHAAENAAAGKLKLSAEELAALDAAFPRGPKPRSLPML 279 + EN A L+++ E+ ALDAAFP + SL ML Sbjct: 242 SVSRIVENRGATDLEITEEDWTALDAAFPPPTRKTSLEML 281 >mlr5327 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Mlo Mesorhizobium loti Length = 281 Score = 254 bits (648), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 135/275 (49%), Positives = 179/275 (65%), Gaps = 9/275 (3%) Query: 9 SGPQVSVIGQGTWYLDRGDRKAA--VAALKRGIDAGMTHIDTAEMY--GDAELVIADAMS 64 SG V V+GQGTW + R+ A V ALK G+D G+T IDTAEMY G AE V+A+A++ Sbjct: 12 SGETVQVLGQGTWKMGEDSRRRADEVNALKLGLDLGLTLIDTAEMYASGGAEEVVAEAIA 71 Query: 65 GRRDELFLVSKVLPSNASRRGTITACERSLKRLKTDRLDCYLLHWRGTTPLAETVAAFDE 124 GRR E+F+VSKVLPSNAS G ACE SLKRL+TDR+D YLLHW G+ PLAETV AF+ Sbjct: 72 GRRAEVFVVSKVLPSNASHAGVQRACENSLKRLRTDRIDLYLLHWPGSVPLAETVEAFEA 131 Query: 125 LIAAGKIRAWGVSNFDTEDLDELLDVAGEGTIACNQVLYHLQERAIEHAVIPWCEQHGVA 184 + AGKIR WGVSNFDTED+D+L + + NQVLY+L R E + PW + G+ Sbjct: 132 VKKAGKIRHWGVSNFDTEDMDDLAGLPDGSNVQTNQVLYNLVRRGPEFDLAPWSRKRGIP 191 Query: 185 VVAYSPFGHNDFPAPSSKAGTVLQSIAQAHKATPRQVALSFLTRLPSVLAIPKASNADHA 244 ++AYSP T L ++A H AT Q+AL+++ ++AIPKAS+ +H Sbjct: 192 LMAYSPVEQGAL-----ARNTGLDAVAARHNATAAQIALAWVMHQDGIIAIPKASSQEHV 246 Query: 245 AENAAAGKLKLSAEELAALDAAFPRGPKPRSLPML 279 +N AA +KL+ +++ LD AFP + R L M+ Sbjct: 247 RQNFAALDIKLTPQDITDLDRAFPPPTRKRGLEMI 281 >STM1288 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Sty Salmonella typhimurium LT2 Length = 285 Score = 252 bits (643), Expect = 7e-67, Method: Compositional matrix adjust. Identities = 133/264 (50%), Positives = 172/264 (65%), Gaps = 5/264 (1%) Query: 16 IGQGTWYL-DRGD-RKAAVAALKRGIDAGMTHIDTAEMYGD--AELVIADAMSGRRDELF 71 IGQGTWY+ +R D R+ V+AL+ G+D G+ IDTAEMY D AE V+ +A++GRRDE F Sbjct: 18 IGQGTWYMGERADQRQREVSALRAGLDLGLRLIDTAEMYADGGAEKVVGEALAGRRDEAF 77 Query: 72 LVSKVLPSNASRRGTITACERSLKRLKTDRLDCYLLHWRGTTPLAETVAAFDELIAAGKI 131 LVSKV P NA + + ACE SL+RLKTD LD YLLHW G+ ETV + LIA GKI Sbjct: 78 LVSKVYPWNAGGQKIVAACEESLRRLKTDYLDLYLLHWAGSFSFEETVEGMERLIAQGKI 137 Query: 132 RAWGVSNFDTEDLDELLDVAGEGTIACNQVLYHLQERAIEHAVIPWCEQHGVAVVAYSPF 191 R WGVSN D +D+ L + G A NQVLYHL R IE+ ++PWC+Q + V+AYSP Sbjct: 138 RRWGVSNLDYDDMQALWRIPGGQQCATNQVLYHLASRGIEYDLLPWCQQQRMPVMAYSPL 197 Query: 192 GHNDFPAPSSKAGTVLQSIAQAHKATPRQVALSFLTRLPSVLAIPKASNADHAAENAAAG 251 V+ IAQAH AT Q+ L+++ P V+AIPKA + +H +NAAA Sbjct: 198 AQAGRLRSGLLNHPVVNEIAQAHNATAAQILLTWVIAHPGVMAIPKAGSTEHVKQNAAAL 257 Query: 252 KLKLSAEELAALDAAFPRGPKPRS 275 ++ LSA ELA LD A+P PK ++ Sbjct: 258 EIALSANELALLDNAWP-APKGKT 280 >yeaE [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Eco Escherichia coli K12 Length = 284 Score = 248 bits (633), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 129/264 (48%), Positives = 169/264 (64%), Gaps = 5/264 (1%) Query: 16 IGQGTWYL--DRGDRKAAVAALKRGIDAGMTHIDTAEMYGD--AELVIADAMSGRRDELF 71 +GQGTWY+ D RK VAAL+ GI+ G+T IDTAEMY D AE V+ +A++G R+++F Sbjct: 17 VGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLREKVF 76 Query: 72 LVSKVLPSNASRRGTITACERSLKRLKTDRLDCYLLHWRGTTPLAETVAAFDELIAAGKI 131 LVSKV P NA + I ACE SL+RL TD LD YLLHW G+ ETVAA ++LIA GKI Sbjct: 77 LVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKI 136 Query: 132 RAWGVSNFDTEDLDELLDVAGEGTIACNQVLYHLQERAIEHAVIPWCEQHGVAVVAYSPF 191 R WGVSN D D+ EL + G A NQVLYHL R IE+ ++PWC+Q + V+AYSP Sbjct: 137 RRWGVSNLDYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPL 196 Query: 192 GHNDFPAPSSKAGTVLQSIAQAHKATPRQVALSFLTRLPSVLAIPKASNADHAAENAAAG 251 V+ IA AH + QV L+++ V+AIPKA+ H +NAA Sbjct: 197 AQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAIPKAATIAHVQQNAAVL 256 Query: 252 KLKLSAEELAALDAAFPRGPKPRS 275 +++LS+ ELA LD A+P PK ++ Sbjct: 257 EVELSSAELAMLDKAYP-APKGKT 279