BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0067.0002.p (325 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0239 [GER] COG0697 Permeases of the drug/metabolite transporte... 216 6e-56 mlr5160 [GER] COG0697 Permeases of the drug/metabolite transport... 167 3e-41 SMc02817 [GER] COG0697 Permeases of the drug/metabolite transpor... 148 1e-35 RSp0133 [GER] COG0697 Permeases of the drug/metabolite transport... 140 4e-33 AGl1685 [GER] COG0697 Permeases of the drug/metabolite transport... 140 5e-33 >PA0239 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 292 Score = 216 bits (550), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 120/289 (41%), Positives = 174/289 (60%), Gaps = 1/289 (0%) Query: 19 AATSKAPARTDRPFKGIALILLSTVFLGTSDVTAKYLSSTLPSIEIAWIRFLVFAMIMTP 78 A+TS PA +D+ +GI LI + + D +K+LS P + + W R+LV ++M Sbjct: 3 ASTSPLPA-SDQTLRGILLICAAVFLFASHDGLSKFLSGFYPIVMVVWARYLVHTLLMVA 61 Query: 79 AMLPGSPLFALRSSRPGLHVLRGAALLGSSLIFITGLGFLPIAEASATSFVSPLFVTALS 138 +P + L +RS RP + + R L+G+SL F TGL +LP+AEA+A +F++PL VTALS Sbjct: 62 VFVPRNGLAVIRSRRPLMQLARALCLIGTSLFFTTGLRYLPLAEATAVNFLAPLLVTALS 121 Query: 139 IAFLGERVGMRRWIATAVGLAGVFIILRPGTSAFHPAAIFPLVSALAWAGTLILTRMMSG 198 + L E+V + +W+A G GV I+RPG + F PAA+FPL SAL + +LTRM++ Sbjct: 122 VPLLKEKVSLGQWLAVLTGFIGVLFIVRPGGALFTPAALFPLGSALCFGLYQLLTRMLAN 181 Query: 199 SERPITVMTYSSIVGVAIVSALVPFVWVTPSWHDIMFGILIGVASTVGQWIVVLAFRYGD 258 S+ P T + I I+S LVPF W TPS + I +G G ++ AFR+ Sbjct: 182 SDSPTTSNFLAGIFNTLIMSLLVPFFWQTPSLLHGLMMIALGGCGMGGHLLLTQAFRHAP 241 Query: 259 ASVLAPFSYTQLLWVSILGFLIFGEVPDSWTILGAGFIVASGLYTAHRE 307 + LAPFSY Q+++ +LG L+FG VPD+W +LG I ASGL A R Sbjct: 242 PATLAPFSYGQIIFAGLLGLLVFGHVPDAWALLGILVICASGLVVAWRR 290 >mlr5160 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 313 Score = 167 bits (423), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 103/295 (34%), Positives = 162/295 (54%), Gaps = 4/295 (1%) Query: 22 SKAPARTDRPFKGIALILLSTVFLGTSDVTAKYLS-STLPSIEIAWIRFLVFAMIMTPAM 80 SK + P I +L + VF D ++KYL + + ++ +AW+RF V +++ + Sbjct: 4 SKRYVESATPPVAILCMLTTYVFFTFLDTSSKYLVLAGVSALIVAWVRFAVHVVLVGTLL 63 Query: 81 LPGSPLFALRSSRPGLHVLRGAALLGSSLIFITGLGFLPIAEASATSFVSPLFVTALSIA 140 R HVLRG L GS++ I L L +AE ++ F P+ +TAL+ Sbjct: 64 RGWRDPLRFRPVNLPAHVLRGVFLFGSTMCNILALRSLQLAETTSIYFFGPMVITALAGP 123 Query: 141 FLGERVGMRRWIATAVGLAGVFIILRPGTSAFHPAAIFPLVSALAWAGTLILTRMMSGSE 200 LGE G RRW+A AGV II RPG F +F L S L+ +I+TR MS +E Sbjct: 124 LLGEWAGWRRWLAILAAFAGVLIITRPGVGVFGIGHLFALGSMLSNCFYVIMTRRMSSTE 183 Query: 201 RPITVMTYSSIVGVAIVSALVPFVWVTPS--WHDIMFGILIGVASTVGQWIVVLAFRYGD 258 +++ +S++ ++ ++PF + P WH + +++GV VG W++V A+R Sbjct: 184 TSESLILFSALAPTVLLLPMLPFSFSLPHDGWHWFIL-LMLGVFGGVGHWLLVQAYRLAT 242 Query: 259 ASVLAPFSYTQLLWVSILGFLIFGEVPDSWTILGAGFIVASGLYTAHRERVRRSQ 313 + LAP+ Y+Q++W+ I G+++F + PD WT++GA IVASGLY HRE R Q Sbjct: 243 TTALAPYPYSQMVWMVISGWIVFKQFPDRWTLVGAAIIVASGLYIVHREHRLRLQ 297 >SMc02817 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 317 Score = 148 bits (374), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 103/298 (34%), Positives = 160/298 (53%), Gaps = 13/298 (4%) Query: 22 SKAPARTDRPFKGIALILLSTVFLGTSDVTAKYLSSTLPSIEIAWIRFLVFAMIMTPAML 81 SKA +R G+ L++LS + D+ +K +T+PS EI RFL+ + + P +L Sbjct: 7 SKAAIDHNRISYGLTLMVLSVLLSPLIDIFSKLAIATVPSAEITAARFLLQIVFILPIVL 66 Query: 82 PGSPLFALRSSRPGLHVLRGAALLGSSLIFITGLGFLPIAEASATSFVSPLFVTALSIAF 141 LF L + LH LRG L+ + L FIT L + +A+A A FV P+ +T L F Sbjct: 67 VRGTLFDLTWRKSALHALRGGLLVVTMLSFITTLKVMEVADAIAIFFVEPIILTILGSIF 126 Query: 142 LGERVGMRRWIATAVGLAGVFIILRPGTSAFHPAAIFPLVSALAWAGTLILTRMMSGSER 201 L E +G RR+ A AVG G ++++P A+ P+V+A A L++TRM++ +E Sbjct: 127 LKETIGWRRYTACAVGFLGSLLVIQPSMQEVGLVALLPIVAAFGLAVFLLVTRMVAQNED 186 Query: 202 PITVMTYSSIVGVAIVSALVPF-----------VWVTPSWHDIMFGILIGVASTVGQWIV 250 P ++ ++ I G AL+ F VW P + + +GV +T+ + Sbjct: 187 PWSMQFHAGIWGGLFCLALLWFGEGSGSSVFDPVW--PDGRAWYYLLGVGVTATISGVLG 244 Query: 251 VLAFRYGDASVLAPFSYTQLLWVSILGFLIFGEVPDSWTILGAGFIVASGLYTAHRER 308 V A+R ASVLAP Y +++ +I G+L+FG++PD+ LG I+ SGLY RER Sbjct: 245 VYAYRAAPASVLAPLQYLEIVSATIFGWLVFGDLPDALKWLGIAIIIGSGLYIIWRER 302 >RSp0133 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 316 Score = 140 bits (353), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 98/297 (32%), Positives = 160/297 (53%), Gaps = 10/297 (3%) Query: 27 RTDRPFKGIALILLSTVFLGTSDVTAKYLSSTLPSIEIAWIRFLVFAMIMTPA-MLPGSP 85 R+ P +GIA ++ + F D KY+S T+P + W R+L F M+ T A +LP Sbjct: 22 RSQHPLQGIAFLIAAVAFFAVFDTLTKYISITVPVVMALWFRYL-FQMVATGATLLPSRG 80 Query: 86 LFALRSSRPGLHVLRGAALLGSSLIFITGLGFLPIAEASATSFVSPLFVTALSIAFLGER 145 LR+ RP L V+RG LL SL L +P+ + +A ++PL VT ++ LGE+ Sbjct: 81 RSLLRTRRPWLQVVRGLLLLLVSLFSFLSLRRMPVGDVTAIVMLTPLVVTFVAAVSLGEQ 140 Query: 146 VGMRRWIATAVGLAGVFIILRPGTSAFHPAAIFPLVSALAWAGTLILTRMMSGSERPITV 205 V RWI A G G +++RPG +AF + PL +A A ++T ++ + T Sbjct: 141 VSATRWIFMAGGFFGALMVIRPGGAAFDWGMLLPLGMVVANAAFQVVTSRLANVDEAGTT 200 Query: 206 MTYSSIVGVAIVSALVPFVW--VTPSWHDIMFGILIGVASTVGQWIVVLAFRYGDASVLA 263 Y+ VG +++ ++PF W + W ++ ILIG+ S+ G ++++A+ ++L Sbjct: 201 QFYTGAVGALLLTCMLPFGWQALGGKWWWLL--ILIGIVSSSGHALLIMAYTRAPVAMLT 258 Query: 264 PFSYTQLLWVSILGFLIFGEVPDSWTILGAGFIV---ASGLYTAHRERVRRSQLLTV 317 P+ Y Q+ + I G+L+F VPD W++ G I A+G + A RER R + L+ V Sbjct: 259 PYLYMQIGFAMIGGWLVFSHVPDGWSVAGIAIIAMCGAAGTWVAARER-RMAMLVAV 314 >AGl1685 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 294 Score = 140 bits (352), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 96/285 (33%), Positives = 151/285 (52%), Gaps = 6/285 (2%) Query: 34 GIALILLSTVFLGTSDVTAKYLSSTLPSIEIAWIRFLVFAM--IMTPAMLPGSPLFALRS 91 G L++ D +K+L S P + +A +R+ FA+ ++ A G A+ + Sbjct: 7 GFLYALVAFTIFAAQDGISKHLGSAYPPVFVAMLRYWAFAVFVLLMAARSAGGIRGAVMA 66 Query: 92 SRPGLHVLRGAALLGSSLIF-ITGLGFLPIAEASATSFVSPLFVTALSIAFLGERVGMRR 150 +RP L + RG LL ++F I + +A + + +PL V ALS+ LGE VG RR Sbjct: 67 NRPWLQISRGV-LLAVQIVFSIFSFAVVGLAHSHSILASAPLIVAALSMPLLGEHVGWRR 125 Query: 151 WIATAVGLAGVFIILRPGTSAFHPAAIFPLVSALAWAGTLILTRMMSGSERPITVMTYSS 210 W A VG GV +IL+P F I V+A A +LTR+ S S+ +T Y+ Sbjct: 126 WCAIFVGFIGVLVILKPDGDGFDNKLIITFVAAFMLALYSVLTRLGSKSDSAMTSFFYTG 185 Query: 211 IVGVAIVSALVPFVWVTPSWHDIMFGILIGVASTVGQWIVVLAFRYGDASVLAPFSYTQL 270 + G A ++ + PF WV + D + + + + G + ++ AF DA+ + PFSY QL Sbjct: 186 VAGAAALTLVGPFYWVPLAPQDWGWMLALCITGMSGHYCLIKAFELADAASVQPFSYYQL 245 Query: 271 LWVSILGFLIFGEVPDSWTILGAGFIVASGLYTAHRERV--RRSQ 313 + VSI+G I+GEV S + GA ++A+GL+T RE V RR++ Sbjct: 246 VLVSIIGVTIYGEVVTSNMVTGAAIVIAAGLFTIWREHVVARRNR 290