BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0066.0067.p (357 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2265 [E] COG2303 Choline dehydrogenase and related flavoprotei... 335 1e-91 Cj0415 [E] COG2303 Choline dehydrogenase and related flavoprotei... 243 4e-64 AGl980 [E] COG2303 Choline dehydrogenase and related flavoprotei... 79 1e-14 RSp0904 [E] COG2303 Choline dehydrogenase and related flavoprote... 70 6e-12 >PA2265 [E] COG2303 Choline dehydrogenase and related flavoproteins Pae Pseudomonas aeruginosa Length = 591 Score = 335 bits (858), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 175/359 (48%), Positives = 229/359 (63%), Gaps = 32/359 (8%) Query: 1 LIRKPNFSARDNSEVVKINVDRSGKHATGVTFVDTSGEKWEQPADLVILSAFSLFNVQLL 60 L + P F R N V+K+N+D G+ ATGVT+VD G + QPA LVI+SAF NV+LL Sbjct: 263 LRQTPLFELRANCNVLKVNLDSDGRQATGVTYVDAQGREIVQPAKLVIISAFQFHNVRLL 322 Query: 61 LHSKIGMPYDPASNTGVIGRNYTHQTISTVNGFFDHKKFNFNPFIASGAIGMCIDEFNGD 120 L S IG PYDP + GV+G+N+ +Q ++T+ FFD K + NPF+ +G G+ +D+FN D Sbjct: 323 LLSGIGKPYDPRTGEGVVGKNFAYQNMATIKAFFD-KDVHTNPFVGTGGGGVAVDDFNAD 381 Query: 121 NFDHGPHGFVGRGLRNANMAMWTNFYLNYGGEFLDAKGNILTXQVQTGARPIESTLTPPG 180 NFDHGP GFVG MW N Q G++PI PPG Sbjct: 382 NFDHGPLGFVG------GSPMWVN---------------------QAGSKPIGGLAVPPG 414 Query: 181 TPKWGAAWKSAVRDNYLSTVKPGTGVHGSSYAYRDVYLGLDPTYKDRFGRPLMQITMDLH 240 TP WG+ WK AV+D Y TV HGS+ YRD YL LDPTYKD +G+PL+++T D Sbjct: 415 TPSWGSGWKQAVKDAYTHTVS--MDAHGSNMTYRDNYLDLDPTYKDAYGQPLLRMTFDWK 472 Query: 241 DNEVKQNRFLTDKFAEIIKAMGADHVAKHYRT--APYDITQYQTTHVNGGAIMGTDPSTS 298 DNE++ +R++T+ +I +AM ++ + ++ YQTTH+ GGAIMG+DP TS Sbjct: 473 DNEIRMSRYVTEHMRKIAEAMNPKAISVSVKNFGDHFNTRVYQTTHLLGGAIMGSDPKTS 532 Query: 299 ALNRYLQHWDVPNLFVLGASAFPQNAGYNPTLTVAALAYWAAAAIRDKYLKNSGRLIDA 357 LNRYLQ WDV N+FV+GASAFPQ GYNPT VAALAYW+A AIR++YLKN G L+ A Sbjct: 533 VLNRYLQSWDVHNVFVMGASAFPQGTGYNPTGLVAALAYWSAKAIREQYLKNPGPLVQA 591 >Cj0415 [E] COG2303 Choline dehydrogenase and related flavoproteins Cje Campylobacter jejuni Length = 573 Score = 243 bits (621), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 142/350 (40%), Positives = 192/350 (54%), Gaps = 37/350 (10%) Query: 7 FSARDNSEVVKINVDRSGKHATGVTFVDT-SGEKWEQPADLVILSAFSLFNVQLLLHSKI 65 ++ R S V +I + + GK TGV FVDT + +++ QPAD+V+L+++ N +LL+ S I Sbjct: 258 YTIRTYSNVTQI-LKKDGK-VTGVKFVDTRTMKEYIQPADIVVLTSYMFNNAKLLMVSNI 315 Query: 66 GMPYDPASNTGVIGRNYTHQTISTVNGFFDHKKFNFNPFIASGAIGMCIDEFNGDNFDHG 125 G YDP + G +GRNY +Q FFD + FN F+ SGA+G D+FNGDNFDH Sbjct: 316 GEQYDPKTGKGTLGRNYCYQMNMGTTAFFDEQ---FNTFMGSGALGTTSDDFNGDNFDHS 372 Query: 126 PHGFVGRGLRNANMAMWTNFYLNYGGEFLDAKGNILTXQVQTGARPIESTLTPPGTPKWG 185 F+ + VQ G RPI+S P G P WG Sbjct: 373 KEKFL---------------------------HGAMIYSVQLGTRPIQSAPLPAGAPTWG 405 Query: 186 AAWKSAVRDNYLSTVKPGTGVHGSSYAYRDVYLGLDPTYKDRFGRPLMQITMDLHDNEVK 245 A +K A+ N+ + G G+S +++ YL LDPTYKD FG PL+++T + D + Sbjct: 406 AEFKKALNYNFTRAIT--VGGQGASLPHKNNYLSLDPTYKDAFGMPLLRLTYNFTDQDRA 463 Query: 246 QNRFLTDKFAEIIKAM-GADHVAKHYRTAPYDITQYQTTHVNGGAIMGTDPSTSALNRYL 304 ++F+TDK AE+ K M G + K Y + YQ+TH GG MG D TS +N YL Sbjct: 464 LHKFITDKTAEVAKRMQGVKSIKKGAYLKDYSVVPYQSTHNTGGTTMGADRETSVVNTYL 523 Query: 305 QHWDVPNLFVLGASAFPQNAGYNPTLTVAALAYWAAAAIRDKYLKNSGRL 354 QHWD NLFV+GA F N+GYNPT TV ALAY A I KY K+ L Sbjct: 524 QHWDADNLFVVGAGNFQHNSGYNPTDTVGALAYRCAEGIL-KYHKSGKSL 572 >AGl980 [E] COG2303 Choline dehydrogenase and related flavoproteins Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 561 Score = 79.0 bits (193), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 94/347 (27%), Positives = 141/347 (40%), Gaps = 62/347 (17%) Query: 6 NFSARDNSEVVKINVDRSGKHATGVTFVDTSGE-KWEQPADLVILSAFSLFNVQLLLHSK 64 N + R S V +I D+ K A GV +D +E AD++ L+A +L + +L++S Sbjct: 253 NLTLRPFSIVKEILYDKDKKKARGVEIIDAETNLTYEYTADIIFLNASTLNSTWVLMNSA 312 Query: 65 IGM-PYDPASNTGVIGRN-----YTHQTISTVNGFFDHKKFNFNPFIASGAIGMCIDEFN 118 + S++G +G N + V+GF D F G I F Sbjct: 313 TDVWEGGLGSSSGELGHNVMDHHFRMGATGQVDGFEDFY------FKGRRPAGFYIPRFR 366 Query: 119 --GDNFDHGPHGFVGRGLRNANMAMWTNFY--LNYGGEFLDAKGNILTXQVQTGARPIES 174 GD+ GF +G +A+ + W LN G ++ D Sbjct: 367 NTGDDKRKYLRGFGYQG--SASRSRWEREIAELNIGADYKD------------------- 405 Query: 175 TLTPPGTPKWGAAWKSAVRDNYLSTVKPGTGVHGSSYAYRDVYLGLDPTYKDRFGRPLMQ 234 TLT PG W T+ G G Y D + LD KD++G P++ Sbjct: 406 TLTEPG------GW----------TI--GMTAFGEMLPYHDNRVKLDHDKKDKWGLPVLS 447 Query: 235 ITMDLHDNEVKQNRFLTDKFAEIIKAMGADHVAKHYRT-APYDITQYQTTHVNGGAIMGT 293 + +++ NE+ + + E+ +A+G +V T AP H G A MG Sbjct: 448 MNVEMKQNELDMREDMVNDAVEMFEAVGIKNVKPSRGTYAPG-----MGIHEMGTARMGR 502 Query: 294 DPSTSALNRYLQHWDVPNLFVLGASAFPQNAGYNPTLTVAALAYWAA 340 DP TS LN Q WD PN+FV + + NP+LT AL AA Sbjct: 503 DPKTSVLNGNNQVWDAPNVFVTDGACMTSASCVNPSLTYMALTARAA 549 >RSp0904 [E] COG2303 Choline dehydrogenase and related flavoproteins Rso Ralstonia solanacearum Length = 647 Score = 70.5 bits (171), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 90/368 (24%), Positives = 154/368 (41%), Gaps = 53/368 (14%) Query: 1 LIRKPNFSARDNSEVVKINVDRSGKHATGVTFVDTSG----EKWEQPADLVILSAFSLFN 56 L ++ N R N++ +++ D + + ATGV ++D + + EQ A+ VI+S ++ Sbjct: 312 LGQRDNAEIRCNAKTLEVLYDAASRRATGVAYLDLTDPDHPRRVEQFAETVIISCGAVQT 371 Query: 57 VQLLLHSKIGMPYDPASNTGVIGRNYTHQTISTVNGFFDHKKFNFNPFIASGAIGMCIDE 116 +LLL S G P +++G +GRN F+ F G+ + Sbjct: 372 SRLLLLS--GPPEGLGNSSGQLGRNAM-----------------FHLF------GLGMRT 406 Query: 117 FNGDNFDHGPHGFVGRGLRNANMAMWTNFYLNYG-GEFLDAKGNILTXQVQTGARPIEST 175 G+ F HG +G N + + +++ G G ++ KG LT + P+E Sbjct: 407 VLGEAFQGRLHGELGP---TGNTSTFDTYFVRDGDGRWI--KGGHLTSAAKK--NPLEDA 459 Query: 176 LTPP-GTPKWGAAWKSAVRDNYLSTVKPGTGVHGSSYAYRDVYLGLDPTYKDRFGRPLMQ 234 + G+ K GA + +N ++ + G + + LDPT+ D +G P+ + Sbjct: 460 VNAVNGSSKAGAFLDQLLVNNRTFEIR----LTGDDLPCPENRVSLDPTHVDEYGVPVAR 515 Query: 235 ITMD----------LHDNEVKQNRFLTDKFAEIIKAMGADHVAKHYRTAPYD-ITQYQTT 283 I+ + NE + + + + A A P I Sbjct: 516 ISRRSISDAAGNKFVGPNEQRLDAAAQGAMKAVFELYAARRGALAAAPKPTQAILSLVGD 575 Query: 284 HVNGGAIMGTDPSTSALNRYLQHWDVPNLFVLGASAFPQNAGYNPTLTVAALAYWAAAAI 343 H G MG DP+TS +NRY + DV N+FV+ +S P G NP +TV A A I Sbjct: 576 HQMGTCRMGEDPATSVVNRYGRLHDVENVFVVDSSFMPTGLGLNPMVTVVANALRVGTHI 635 Query: 344 RDKYLKNS 351 + + S Sbjct: 636 VTRLQQGS 643