BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0066.0015.p (327 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0136 [E] COG0346 Lactoylglutathione lyase and related lyase... 388 e-108 DRA0224 [E] COG0346 Lactoylglutathione lyase and related lyases ... 273 4e-73 SSO2054 [E] COG0346 Lactoylglutathione lyase and related lyases ... 189 9e-48 SSO1223 [E] COG0346 Lactoylglutathione lyase and related lyases ... 102 1e-21 >BMEII0136 [E] COG0346 Lactoylglutathione lyase and related lyases Bme Brucella melitensis Length = 331 Score = 388 bits (997), Expect = e-108, Method: Compositional matrix adjust. Identities = 183/326 (56%), Positives = 232/326 (71%), Gaps = 1/326 (0%) Query: 1 MPVPTHVFDPPFNIIRCSHAVLDVTDLDKSAAFYEKTIGLHIEDRDDKSVYLRASEEHQH 60 MP+PT PPFNI+R SH L VTDL KS AFY T+GL + D ++YLRA EE H Sbjct: 6 MPLPTPNLHPPFNIVRLSHVELGVTDLTKSRAFYVDTLGLQVTDESADAIYLRALEERGH 65 Query: 61 HSVVLRKAPKAACNRLGFKVGNDGDLDKAAAFFSENGIAYAFVDQPFQGRTLQFTDPFGF 120 H +VLRK KA LGFK+ ++ D D+A FF G+ +V++P+Q RTL+ DP G Sbjct: 66 HCIVLRKTDKAEARDLGFKLYSEDDFDRAEHFFKGKGLPVEWVERPYQSRTLRTRDPHGI 125 Query: 121 QIELYAAMEKRPHLLRRYDLYKGCHPQRLDHFNVFAAEVQDTVDFYARLGFRLTEYAEED 180 +E Y+ M++ P + ++Y LYKG P R+DHFN F+ V ++V FY LGFR+TEY E D Sbjct: 126 PLEFYSRMDRLPPIHQKYALYKGVKPLRIDHFNCFSPNVDESVAFYNELGFRVTEYTE-D 184 Query: 181 GDNGRIAAAWMHRKGNVHDFAITNGRGPRLHHIAYWVPTAMNIVHLCDVMASSGFLKNIE 240 + GR+ AAW HRKG VHD TNG+GPRLHH A+WVPT +NI+ L D+M+++G+L NIE Sbjct: 185 AETGRLWAAWTHRKGGVHDITFTNGKGPRLHHTAFWVPTPLNIIDLLDLMSTTGWLANIE 244 Query: 241 RGPGRHGISNAFFLYIRDPDGHRIELYTSDYFTGDHDHEPLRWSLRDPRRQTLWGAPAPR 300 RGPGRHGISNAFFLY+RDPDGHRIE+Y SDY T D D EP++W L+DP+RQTLWGAPAP+ Sbjct: 245 RGPGRHGISNAFFLYVRDPDGHRIEIYCSDYQTVDPDLEPIKWDLKDPQRQTLWGAPAPK 304 Query: 301 SWFEEGSTFAGQAVREPRFVADVLVA 326 SWFEEGS FA + A +VA Sbjct: 305 SWFEEGSLFASVQPVDSVLKAQPIVA 330 >DRA0224 [E] COG0346 Lactoylglutathione lyase and related lyases Dra Deinococcus radiodurans Length = 340 Score = 273 bits (698), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 138/301 (45%), Positives = 196/301 (65%), Gaps = 7/301 (2%) Query: 13 NIIRCSHAVLDVTDLDKSAAFYEKTIGLHIEDRDDKSVYLRASEEHQHHSVVLRKAPKAA 72 +IIR + AV V+DL+ S FY +G+++ + ++YLR E+ + ++ L + + Sbjct: 20 DIIRIAQAVFTVSDLNASREFYVDLLGMNVLHEESGALYLRGVEDREW-TLKLEQCREGE 78 Query: 73 CNR---LGFKVGNDGDLDKAAAFFSENGIAYAFVDQPFQGRTLQFTDPFGFQIELYAAME 129 R LG++V ++ LD A G+ + + ++ + R L+ DPFG + Y ++ Sbjct: 79 LPRVRHLGYRVRDEASLDTLLALADAQGLPHRWEEELDRPRMLRMQDPFGIPLAFYLEVK 138 Query: 130 KRPHLLRRYDLYKGCHPQRLDHFNVFAAEVQDTVDFY-ARLGFRLTEYAEEDGDNGRIAA 188 P LL+ Y ++G QR+DH NV +V+ T+D+Y A LGFR++EY ++ + + A Sbjct: 139 TYPWLLQNYHQHRGPGLQRVDHCNVRVPDVKATLDWYGAELGFRVSEYTVDEQE--QYWA 196 Query: 189 AWMHRKGNVHDFAITNGRGPRLHHIAYWVPTAMNIVHLCDVMASSGFLKNIERGPGRHGI 248 AW+ R+G VHDFA+TNG GP LHH AYW+P AM+I+ CD++A + + IERGPGRHG+ Sbjct: 197 AWIQRRGGVHDFALTNGAGPCLHHWAYWMPDAMSIIKTCDILAGARMPERIERGPGRHGV 256 Query: 249 SNAFFLYIRDPDGHRIELYTSDYFTGDHDHEPLRWSLRDPRRQTLWGAPAPRSWFEEGST 308 SNAFFLYIRDPDGHRIELYTSDY T D D EP+RW DPRRQTLWGA PRSWFE+ S Sbjct: 257 SNAFFLYIRDPDGHRIELYTSDYITVDPDFEPIRWLRDDPRRQTLWGAKTPRSWFEDASP 316 Query: 309 F 309 Sbjct: 317 L 317 >SSO2054 [E] COG0346 Lactoylglutathione lyase and related lyases Sso Sulfolobus solfataricus Length = 316 Score = 189 bits (479), Expect = 9e-48, Method: Compositional matrix adjust. Identities = 105/300 (35%), Positives = 164/300 (54%), Gaps = 9/300 (3%) Query: 12 FNIIRCSHAVLDVTDLDKSAAFYEKTIGLHIEDRDDKSVYLRASEEHQHHSVVLRKAPKA 71 N +R SH + V+DLDK+ FY + +G ++D +YLR EE QHHS++L+KA A Sbjct: 3 INTLRTSHVCIRVSDLDKARYFYSELLGFVETEKDGDYIYLRGIEEGQHHSLILKKANSA 62 Query: 72 ACNRLGFKVGNDGDLDKAAAFFSENGIAYAFVDQPFQGRTLQFTDPFGFQIELYAAMEKR 131 + +GF+V +LDKA G + L F P G I LY ME Sbjct: 63 GLSYIGFRVSKGEELDKAREELENLGHKVRKFREKGINEALLFESPEGIPILLYYDMEYV 122 Query: 132 PHLLRRYDLYKGCHPQRLDHFNVFAAEVQDTVDFYAR-LGFRLTE-YAEEDGDNGRIAAA 189 L + ++G P RL H N +++ ++F+ R +G+ TE + ++DG+ +A Sbjct: 123 GDLRLAFHRHRGVSPVRLAHVNYMVKDLERELEFFKRFMGYYETERFLDKDGN---LAVV 179 Query: 190 WMHRKGNVHDFAI--TNGRGPRLHHIAYWVPTAMNIVHLCDVMASSGFLKNIERGPGRHG 247 W+ R+G+ H+ AI ++ P HH Y+V +++ D++AS G +IERGPGRHG Sbjct: 180 WLTRRGDSHEIAIAKSSKNVPGFHHETYYVHDVKDVIKAPDILASVGLWDSIERGPGRHG 239 Query: 248 ISNAFFLYIRDPDGHRIELYTSDYFTGDHDH-EPLRWSLRDPR-RQTLWGAPAPRSWFEE 305 ++ +++Y+RD D +RIE +T+DY D D +P+ W+ R R WG P P+SW E Sbjct: 240 VTEGYYIYLRDFDKNRIEFFTNDYVVLDPDKWKPIVWTYDQLRYRSDFWGRPIPQSWLTE 299 >SSO1223 [E] COG0346 Lactoylglutathione lyase and related lyases Sso Sulfolobus solfataricus Length = 335 Score = 102 bits (254), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 83/289 (28%), Positives = 141/289 (48%), Gaps = 25/289 (8%) Query: 27 LDKSAAFYEKTIGLHIEDRDDKSVYLRASEEHQHHSVVLRKAPKAACNRLGFKVGNDGDL 86 +D + F++ +GLH R D+SVYLR E+ +S+ + ++ A + ++ ++ DL Sbjct: 19 IDDTLWFFKDILGLHEVGRKDRSVYLRGWEDWYAYSLKVTESDTAGVKEIVWRTYSEKDL 78 Query: 87 DKAAAFFSENGIAYAFVD-QPFQG--RTLQFTDPFG------FQIELY-AAMEKRPHLLR 136 + + NG+ + + +P G + +F P G ++++++ A+ E R Sbjct: 79 IDSINIVNSNGLGLGWDEGEPDMGVGKGYKFILPSGQIGKLVWEMKIWRASGELRSGYKA 138 Query: 137 R--YDLYKGCHPQRLDHFNVFA---AEVQDTVDFYARLGFRLTEYAEEDGDNGRIAAAWM 191 R KG + L H +FA + TV+ RL F++ E +E GD RIA WM Sbjct: 139 RPMKKPTKGVQAKDLSHIFIFAYNDESLAKTVELLKRLTFKVNEILKE-GDK-RIAY-WM 195 Query: 192 HRKGNVHDFAIT---NGRGPRLHHIAYWVPTAMNIVHLCDVMASSGFLKNIERGPGRHGI 248 G HD A++ +G RL+H+ + V A +I+ D G I GP RHGI Sbjct: 196 AVNGTAHDLAVSLDPSGVPARLNHVTFNVDYADDILKAADFYTDYGL--EIVGGPLRHGI 253 Query: 249 SNAFFLYIRDPDGHRIELYTSDYFTGDHDHEPLRWSLRDPRRQTL--WG 295 +++ LY+++P G+ IEL Y D EP+ W ++ + L WG Sbjct: 254 TDSHSLYVKEPGGNVIELLHGGYLNVVPDWEPIVWDTKEDENRWLYYWG 302