BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0064.0002.p         (289 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

YPO1933 [R] COG3618 Predicted metal-dependent hydrolase of the T...   238   9e-63
RSp0233 [R] COG3618 Predicted metal-dependent hydrolase of the T...   123   5e-28
AGl3341 [R] COG3618 Predicted metal-dependent hydrolase of the T...   100   3e-21

>YPO1933 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel
           fold Ype Yersinia pestis
          Length = 289

 Score =  238 bits (608), Expect = 9e-63,   Method: Compositional matrix adjust.
 Identities = 136/297 (45%), Positives = 163/297 (54%), Gaps = 18/297 (6%)

Query: 1   MAASEIPACLPPRPVTPPREKLPPKACDTHAHVFGPADRFPYAGDRSYTPPDAPLATYLG 60
           M  S     +P   + P    LP  ACD+HAHV  P   +P   +RSYTPP AP   YL 
Sbjct: 1   MKNSSANCPVPFDIMEPSIFALPEDACDSHAHVISPRAIYPMVAERSYTPPPAPEEKYLS 60

Query: 61  MLDTLGFSRGVLVQGSAHGHDNSAMLDALQREPARLRGVAVA---------DXWHVLGVR 111
           ML   G SRGVLVQ S +G DN  ML  L+R P  LRGVAV              + GVR
Sbjct: 61  MLAATGMSRGVLVQISVYGSDNRYMLQVLKRHPEYLRGVAVVTEDVTDQELQDMALAGVR 120

Query: 112 GLGFNHFFRGGQLHYRGGIPLNVAETHAGVMAELGWHLQLWIDVKDLPDTIPTLKALGLP 171
           GL  N  F        GGI  +  E  A  +A LGWH+Q  +DV+ LP  IP +K L  P
Sbjct: 121 GLRINVLF-------GGGIGFDAMENLASKIAPLGWHMQFLMDVRQLPALIPRMKKLPCP 173

Query: 172 VVVDHMGRTDAGAGINTAGFQSLLRAVDEGWCWAKLSGAHRLSQRAPD-YPDARPFHEAL 230
            V+DHMG      G+N  G+Q+LL  V E   W KLSGA+R+S+   D Y D  PF + L
Sbjct: 174 CVIDHMGHMPVSLGLNHPGYQTLLHMVREYGWWVKLSGAYRISESWQDGYLDVVPFAQKL 233

Query: 231 VSANPERLVWGGDWPHPRVEGEMPDAGHLLDLFHEWTPDAATRHRILVDNPARLYGF 287
           +   P+R+VWG DWPH  V   MPD G L +L   W PD   R+RILVDNPARLY F
Sbjct: 234 IETAPDRMVWGSDWPHVSV-SRMPDTGGLRNLLAAWVPDEQVRNRILVDNPARLYDF 289


>RSp0233 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel
           fold Rso Ralstonia solanacearum
          Length = 302

 Score =  123 bits (309), Expect = 5e-28,   Method: Compositional matrix adjust.
 Identities = 109/300 (36%), Positives = 140/300 (46%), Gaps = 26/300 (8%)

Query: 1   MAASEIPACLPPRPVTPPREKLPPKACDTHAHVFGPADRFPYAGDRSYTPP-DAPLATYL 59
           + A+ +  C+  R +  P  ++     DTHAHVF      P AG R Y P  DA L  YL
Sbjct: 15  LGATALAGCVT-RGMPAPTARI--TGIDTHAHVFKRG--LPLAGARRYAPSYDATLPAYL 69

Query: 60  GMLDTLGFSRGVLVQGSAHGHDNSAMLDALQREPARLRGVAVAD---------XWHVLGV 110
             LD  G S GVL+Q S  G DNS +L AL++ P RLRGVAV D           +  G+
Sbjct: 70  AQLDAHGLSHGVLIQPSFLGGDNSYLLAALRQAPQRLRGVAVIDPAAPEPFLAQLNAEGI 129

Query: 111 RGLGFNHFFRGGQLHYRGGIPLNVAETHAGVMAELGWHLQLWIDVKDLPDTIPTLKALGL 170
            G+  N     G    +   P   A  H   +  LGWH++L      LP  +P L    +
Sbjct: 130 VGIRLNLI---GAPDPQLRAPAWQAALHR--LHALGWHVELHTQAHRLPALLPPLLEAQV 184

Query: 171 PVVVDHMGRTDAGAGINTAGFQSLLRAVDEGWCWAKLSGAHRLSQRAPDYPDARPFHEAL 230
            VVVDH GR D    +   GF +LL A      W K+SGA+R          A      L
Sbjct: 185 DVVVDHFGRPDPALSVEDPGFAALLAAGRTRRVWVKVSGAYRNGDAGRGEAIALAAMPRL 244

Query: 231 VSA-NPERLVWGGDWPHPRVEGEM--PDAGHLLDLFHEWTPDAATRHRILVDNPARLYGF 287
             A   +RLVWG DWPH + E  +    A    D      PDA  RH++LV+ PARL+ F
Sbjct: 245 KDALGTDRLVWGSDWPHTQYESRIGYDSARAFADTL---LPDAGDRHQVLVETPARLFRF 301


>AGl3341 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel
           fold Atu Agrobacterium tumefaciens strain C58 (Cereon)
          Length = 292

 Score =  100 bits (250), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 74/280 (26%), Positives = 109/280 (38%), Gaps = 12/280 (4%)

Query: 16  TPPREKLPPKACDTHAHVFGPADRFPYAGDRSYTPPDAPLATYLGMLDTLGFSRGVLVQG 75
           T P    P  A DT  H++ P       G             Y  ++  LG  R ++ QG
Sbjct: 11  TAPNPAFPRGAVDTQMHMYLPGYPALPGGPGLPPGALPGPEDYRRLMQWLGIDRVIITQG 70

Query: 76  SAHGHDNSAMLDALQREPARLRGVAVADXWHVLGVRGLGFNHFFRGGQLHYR------GG 129
           +AH  DN   L  +         V + D                  G +  R      G 
Sbjct: 71  NAHQRDNGNTLACVAEMGEAAHAVVIIDA----TTTEKDMEKLTAAGTVGARIMDLPGGA 126

Query: 130 IPLNVAETHAGVMAELGWHLQLWIDVKDLPDTIPTLKALGLPVVVDHMGRTDAGAGINTA 189
           + L+  +          W + +  D   L D +P L+ +    V DH G+   G   +  
Sbjct: 127 VNLSELDAVDERAHAADWMVAVQFDGNGLLDHLPRLQKIRSRWVFDHHGKFFKGIRTDGP 186

Query: 190 GFQSLLRAVDEGWCWAKLSGAHRLSQRAPDYPDARPFHEALVSANPERLVWGGDWPHPRV 249
              +LL+ +D G  W K +G +  S+++  Y D   F   + +  PER+VWG +WPH  V
Sbjct: 187 EMAALLKLIDRGNLWFKFAGVYESSRKSWPYADVAAFSRVIAAHAPERIVWGTNWPHNSV 246

Query: 250 E--GEMPDAGHLLDLFHEWTPDAATRHRILVDNPARLYGF 287
                 PD   L +L   W PD A RHR LV+NP  L+  
Sbjct: 247 RETAAYPDDARLAELTLGWLPDEAARHRALVENPEALFKL 286