BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0062.0010.p (456 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Rv2424c [L] COG3547 Transposase and inactivated derivatives Mtu ... 132 2e-30 MT2497 [L] COG3547 Transposase and inactivated derivatives MtC M... 129 1e-29 Rv2177c [L] COG3547 Transposase and inactivated derivatives Mtu ... 76 1e-13 MT2233 [L] COG3547 Transposase and inactivated derivatives MtC M... 76 1e-13 SSO1556 [L] COG3547 Transposase and inactivated derivatives Sso ... 65 3e-10 >Rv2424c [L] COG3547 Transposase and inactivated derivatives Mtu Mycobacterium tuberculosis H37Rv Length = 333 Score = 132 bits (332), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 111/365 (30%), Positives = 166/365 (45%), Gaps = 48/365 (13%) Query: 94 VNARYAKNVPGRKTDVSDAAWLRQLHSYGLLRGSFRPDAEIATLRAYLRQRERLVEYAAA 153 + R + PGRKTD+ DA WL L GLLRG P A+I R +R R +LVE+ + Sbjct: 1 MQCRAREERPGRKTDLLDAEWLVHLLECGLLRGWLIPPADIKAARDVIRYRRKLVEHRTS 60 Query: 154 HIQHMQKALMEMNLQLHHVVTDITGATGMRIIRAIVAGERNPDVLATYRDVRCHSSIATI 213 +Q + L + ++ V + +T + ++ A++ GER P VLA S I + Sbjct: 61 KLQRLGNVLQDAGIKADSVASSVTPKSVRAMVEALIDGERRPAVLADLARGSMRSKIPDL 120 Query: 214 RAALVGNDRHEHVFALTQSLELYDVYQAKMLDCDRKLEVLIAALNNKGAKPTGKLSKPRI 273 + AL G R + AL L L + Q L+ +I AL+ + Sbjct: 121 QRALEG--RFDDHHALMCRLHLAHLDQ---------LDAMIGALDEQ------------- 156 Query: 274 KTKQVNAPTFDVRTALYGVLGVDLTEIHGLGPSLALKLVGECGTDLRAW-PSAKHFTSWL 332 +Q+ P F R L + I G+G + ++ E G D AW PSA+H SW+ Sbjct: 157 -IEQLMHP-FCARREL-------IASIPGIGVGASATVISEIGADPAAWFPSAEHLASWV 207 Query: 333 CLAPGNKISGGKVLSSRTRRSSSRAAALLRLAATTVGRSDTALGAFYRR-------LSSR 385 L PGN S GK R + +L A R+D L +YRR S Sbjct: 208 RLCPGNHESAGKRHHGARRTGNQHLQPVLVECAWAAVRTDGYLREYYRRQVRKFGGFRSP 267 Query: 386 AGKSKAVTATARKIAVLFYNTLRHGMHYRDPGADHY-----EQKYRGRVLANLQRRAKSL 440 A KA+T A K+ V+ ++ L G ++D GAD++ K R R++A L+ A+ L Sbjct: 268 AANKKAITTVAHKLIVIIWHVLATGRPHQDLGADYFTTRMDPDKERRRLVAKLE--AQGL 325 Query: 441 GFVLQ 445 G L+ Sbjct: 326 GVTLE 330 >MT2497 [L] COG3547 Transposase and inactivated derivatives MtC Mycobacterium tuberculosis CDC1551 Length = 333 Score = 129 bits (324), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 110/365 (30%), Positives = 164/365 (44%), Gaps = 48/365 (13%) Query: 94 VNARYAKNVPGRKTDVSDAAWLRQLHSYGLLRGSFRPDAEIATLRAYLRQRERLVEYAAA 153 + R + PGRKTD+ DA WL L GLLRG P A+I R +R R +LVE+ + Sbjct: 1 MQCRAREERPGRKTDLLDAEWLVHLLECGLLRGWLIPPADIKAARDVIRYRRKLVEHRTS 60 Query: 154 HIQHMQKALMEMNLQLHHVVTDITGATGMRIIRAIVAGERNPDVLATYRDVRCHSSIATI 213 +Q + L + ++ V + +T + ++ A++ GER P VLA S I + Sbjct: 61 KLQRLGNVLQDAGIKADSVASSVTPKSVRAMVEALIDGERRPAVLADLARGSMRSKIPDL 120 Query: 214 RAALVGNDRHEHVFALTQSLELYDVYQAKMLDCDRKLEVLIAALNNKGAKPTGKLSKPRI 273 + AL G R + AL L L + Q L+ +I AL+ + Sbjct: 121 QRALEG--RFDDHHALMCRLHLAHLDQ---------LDAMIGALDEQ------------- 156 Query: 274 KTKQVNAPTFDVRTALYGVLGVDLTEIHGLGPSLALKLVGECGTDLRAW-PSAKHFTSWL 332 +Q+ P F R L + I G+G + ++ E G D AW PSA+H SW+ Sbjct: 157 -IEQLMHP-FCARREL-------IASIPGIGVGASATVISEIGADPAAWFPSAEHLASWV 207 Query: 333 CLAPGNKISGGKVLSSRTRRSSSRAAALLRLAATTVGRSDTALGAFYRR-------LSSR 385 L PGN S GK R + +L A R+D L +YRR S Sbjct: 208 RLCPGNHESAGKRHHGARRTGNQHLQPVLVECAWAAVRTDGYLREYYRRQVRKFGGFRSP 267 Query: 386 AGKSKAVTATARKIAVLFYNTLRHGMHYRDPGADHY-----EQKYRGRVLANLQRRAKSL 440 A KA+ A K+ V+ ++ L G +D GAD++ K R R++A L+ A+ L Sbjct: 268 AANKKAIXXVAHKLIVIIWHVLATGRPXQDLGADYFTTRMDPDKERRRLVAKLE--AQGL 325 Query: 441 GFVLQ 445 G L+ Sbjct: 326 GVTLE 330 >Rv2177c [L] COG3547 Transposase and inactivated derivatives Mtu Mycobacterium tuberculosis H37Rv Length = 221 Score = 76.3 bits (186), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 54/162 (33%), Positives = 78/162 (48%), Gaps = 15/162 (9%) Query: 297 LTEIHGLGPSLALKLVGECGTDLRAW-PSAKHFTSWLCLAPGNKISGGKVLSSRTRRSSS 355 + I G+G + ++ E G D AW PSA+H SW+ L PGN S GK R + Sbjct: 59 IASIPGIGVGASATVISEIGADPAAWFPSAEHLASWVRLCPGNHESAGKRHHGARRTGNQ 118 Query: 356 RAAALLRLAATTVGRSDTALGAFYRR-------LSSRAGKSKAVTATARKIAVLFYNTLR 408 +L A R+D L +YRR S A KA+ A A K+ V+ ++ L Sbjct: 119 HLQPVLVECAWAAVRTDGYLREYYRRQVRKFGGFRSPAANKKAIIAVAHKLIVIIWHVLA 178 Query: 409 HGMHYRDPGADHY-----EQKYRGRVLANLQRRAKSLGFVLQ 445 G Y+D GAD++ K R R++A L+ A+ LG L+ Sbjct: 179 TGRPYQDLGADYFTTRMDPDKERRRLVAKLE--AQGLGVTLE 218 >MT2233 [L] COG3547 Transposase and inactivated derivatives MtC Mycobacterium tuberculosis CDC1551 Length = 221 Score = 76.3 bits (186), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 54/162 (33%), Positives = 78/162 (48%), Gaps = 15/162 (9%) Query: 297 LTEIHGLGPSLALKLVGECGTDLRAW-PSAKHFTSWLCLAPGNKISGGKVLSSRTRRSSS 355 + I G+G + ++ E G D AW PSA+H SW+ L PGN S GK R + Sbjct: 59 IASIPGIGVGASATVISEIGADPAAWFPSAEHLASWVRLCPGNHESAGKRHHGARRTGNQ 118 Query: 356 RAAALLRLAATTVGRSDTALGAFYRR-------LSSRAGKSKAVTATARKIAVLFYNTLR 408 +L A R+D L +YRR S A KA+ A A K+ V+ ++ L Sbjct: 119 HLQPVLVECAWAAVRTDGYLREYYRRQVRKFGGFRSPAANKKAIIAVAHKLIVIIWHVLA 178 Query: 409 HGMHYRDPGADHY-----EQKYRGRVLANLQRRAKSLGFVLQ 445 G Y+D GAD++ K R R++A L+ A+ LG L+ Sbjct: 179 TGRPYQDLGADYFTTRMDPDKERRRLVAKLE--AQGLGVTLE 218 >SSO1556 [L] COG3547 Transposase and inactivated derivatives Sso Sulfolobus solfataricus Length = 245 Score = 65.1 bits (157), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 48/150 (32%), Positives = 73/150 (48%), Gaps = 7/150 (4%) Query: 22 AIDVG-SKMHMAAVNPACT----DVPVRSFGTFTRDLHELADWFKTCGVTSVA-MESTGV 75 AIDV K+ +A T +V V F D + + K G MESTG Sbjct: 11 AIDVSRDKLTVAKAELVITQEKREVEVNEVREFKYDNEGIEELIKFLGEYKEGIMESTGP 70 Query: 76 YWIPVYEILEQRGFEVILVNARYAKNVPGRKTDVSDAAWLRQLHSYGLLRGSFRPDAEIA 135 Y+ ++E L ++G++V L+N + K V G+KTD DA L + G ++GS+ P EI Sbjct: 71 YFFYLHEELTEKGYKVTLINPLHLKEVFGKKTDKLDAQRLAKAFILGAVKGSYIPTGEIR 130 Query: 136 TLRAYLRQRERLVEYAAAHIQHMQKALMEM 165 LR R RE L+ +++ + +EM Sbjct: 131 ELRELTRYRESLMR-KITQVKNEIRKFLEM 159