BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0060.0005.p         (196 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

mlr1707 Non COG                                                       195   7e-50
SMc00516 [R] COG3552 Protein containing von Willebrand factor ty...    97   3e-20
mlr0089 Non COG                                                        96   5e-20
MT0384 [S] COG3427 Uncharacterized conserved protein MtC Mycobac...    92   7e-19
Rv0368c [R] COG3552 Protein containing von Willebrand factor typ...    92   7e-19

>mlr1707 Non COG
          Length = 331

 Score =  195 bits (495), Expect = 7e-50,   Method: Compositional matrix adjust.
 Identities = 108/191 (56%), Positives = 131/191 (68%)

Query: 1   VRNDGEVLRLGRMRRRQRPRKILFLIDVSGSMKARTEENMKLAHVLVQAAGNVEVFTFGT 60
           V  DG+V      RR+  PRK+L LIDVSGSMK  T + +KLAH  VQ A   E+FTFGT
Sbjct: 127 VSADGDVPSPLLRRRQTVPRKLLLLIDVSGSMKLHTADYLKLAHAAVQGADRAEIFTFGT 186

Query: 61  RLTRVTPALRLKRREQALNAASFLVSDWDGGTRIGDALQAFLAVPRFGGYARGAAVVIVS 120
           RLTR+T ALR++ R QAL  A+  V DWDGGTR+G  L AFL+VPRF  +ARGAAVVI+S
Sbjct: 187 RLTRITSALRIRDRNQALARAAAQVDDWDGGTRMGPTLLAFLSVPRFSSFARGAAVVILS 246

Query: 121 DGLERGDPAALRDAVAKLSRRAWRVSWLTPLATSPGFTPQTEALIAIQRFVDDLVDGGSS 180
           D LERGD A L  A+ +LS RA+R+S  TPLA  P F P T AL AI   +DDL+DG S 
Sbjct: 247 DALERGDHAELETAMRRLSARAFRLSLATPLAGDPRFRPATAALRAILPDLDDLIDGSSL 306

Query: 181 AAVVAHLLSLG 191
            ++   +LSL 
Sbjct: 307 TSLTDFILSLA 317


>SMc00516 [R] COG3552 Protein containing von Willebrand factor type A (vWA)
           domain Sme Sinorhizobium meliloti
          Length = 420

 Score = 96.7 bits (239), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 56/153 (36%), Positives = 79/153 (51%)

Query: 22  ILFLIDVSGSMKARTEENMKLAHVLVQAAGNVEVFTFGTRLTRVTPALRLKRREQALNAA 81
           ++ L D+SGSM   T   +   H L +    V  F FGTRLT VT  +R +  ++AL+  
Sbjct: 222 LVVLADISGSMSKYTRIFLHFLHALTEQRHRVHTFLFGTRLTNVTRQMRNRDPDEALDDC 281

Query: 82  SFLVSDWDGGTRIGDALQAFLAVPRFGGYARGAAVVIVSDGLERGDPAALRDAVAKLSRR 141
              V DW GGTRIG+ L  F          +GA V++++DGLER D A L   + +L R 
Sbjct: 282 IAAVKDWSGGTRIGETLHDFNRRWSRRVLGQGAVVLLMTDGLERDDTAELETEIDRLHRS 341

Query: 142 AWRVSWLTPLATSPGFTPQTEALIAIQRFVDDL 174
             R+ WL PL    GF  +   + A+   VD+ 
Sbjct: 342 CRRLVWLNPLLRFDGFEARARGVRAMLPHVDEF 374


>mlr0089 Non COG
          Length = 421

 Score = 95.9 bits (237), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 56/153 (36%), Positives = 78/153 (50%)

Query: 22  ILFLIDVSGSMKARTEENMKLAHVLVQAAGNVEVFTFGTRLTRVTPALRLKRREQALNAA 81
           ++ L D+SGSM   T   +   H L +    V  F FGTRLT +T  +R +  + AL   
Sbjct: 231 LVVLADISGSMSQYTRIFLHFLHALTEKRRRVHTFVFGTRLTNLTRQMRHRDPDAALADC 290

Query: 82  SFLVSDWDGGTRIGDALQAFLAVPRFGGYARGAAVVIVSDGLERGDPAALRDAVAKLSRR 141
           S  V DW GGTRIGD L  F          +GA V++++DGLER D A L   + +L + 
Sbjct: 291 SAAVKDWSGGTRIGDTLAEFNLAWSRRVLGQGAVVLLITDGLERDDVAGLSQEMERLHKS 350

Query: 142 AWRVSWLTPLATSPGFTPQTEALIAIQRFVDDL 174
             R+ WL PL    GF  +   + A+   VD+ 
Sbjct: 351 CRRLIWLNPLLRFDGFQARARGVKAMLPHVDEF 383


>MT0384 [S] COG3427 Uncharacterized conserved protein MtC Mycobacterium
           tuberculosis CDC1551 [R] COG3552 Protein containing von
           Willebrand factor type A (vWA) domain MtC Mycobacterium
           tuberculosis CDC1551
          Length = 403

 Score = 92.0 bits (227), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 66/171 (38%), Positives = 91/171 (53%), Gaps = 3/171 (1%)

Query: 26  IDVSGSMKARTEENMKL--AHVLVQAAGNVEVFTFGTRLTRVTPALRLKRREQALNAASF 83
            DVS SM+      ++L  A VL +A G+ EVF F T LTR+T  L  +  E AL+ A+ 
Sbjct: 234 CDVSRSMQPYAAIYLRLMRAAVLRRAGGHPEVFAFSTSLTRLTSVLSHRSAEMALHRANA 293

Query: 84  LVSDWDGGTRIGDALQAFLAVPRFGGYARGAAVVIVSDGLERGDPAALRDAVAKLSRRAW 143
            V+D  GGT IG ++ A LA P  G   RGA V+I SDG +   P  L  A+ ++ RRA 
Sbjct: 294 RVTDRYGGTFIGRSVAALLAPPH-GNALRGAVVIIASDGWDSDPPDVLVHALTRVRRRAE 352

Query: 144 RVSWLTPLATSPGFTPQTEALIAIQRFVDDLVDGGSSAAVVAHLLSLGTRR 194
            + WL P A  P F P+  ++ A   + D  +   S A +   LL+L   R
Sbjct: 353 LLVWLNPRAAHPEFQPRAGSMAAALPYCDLFLPAHSLAGLHQLLLALAGAR 403


>Rv0368c [R] COG3552 Protein containing von Willebrand factor type A (vWA)
           domain Mtu Mycobacterium tuberculosis H37Rv
          Length = 403

 Score = 92.0 bits (227), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 66/171 (38%), Positives = 91/171 (53%), Gaps = 3/171 (1%)

Query: 26  IDVSGSMKARTEENMKL--AHVLVQAAGNVEVFTFGTRLTRVTPALRLKRREQALNAASF 83
            DVS SM+      ++L  A VL +A G+ EVF F T LTR+T  L  +  E AL+ A+ 
Sbjct: 234 CDVSRSMQPYAAIYLRLMRAAVLRRAGGHPEVFAFSTSLTRLTSVLSHRSAEMALHRANA 293

Query: 84  LVSDWDGGTRIGDALQAFLAVPRFGGYARGAAVVIVSDGLERGDPAALRDAVAKLSRRAW 143
            V+D  GGT IG ++ A LA P  G   RGA V+I SDG +   P  L  A+ ++ RRA 
Sbjct: 294 RVTDRYGGTFIGRSVAALLAPPH-GNALRGAVVIIASDGWDSDPPDVLVHALTRVRRRAE 352

Query: 144 RVSWLTPLATSPGFTPQTEALIAIQRFVDDLVDGGSSAAVVAHLLSLGTRR 194
            + WL P A  P F P+  ++ A   + D  +   S A +   LL+L   R
Sbjct: 353 LLVWLNPRAAHPEFQPRAGSMAAALPYCDLFLPAHSLAGLHQLLLALAGAR 403