BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0059.0242.p (441 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 380 e-105 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 362 e-100 RSp0182 [GEPR] COG0477 Permeases of the major facilitator superf... 358 2e-98 AGc4908 [GEPR] COG0477 Permeases of the major facilitator superf... 349 6e-96 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 343 5e-94 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 380 bits (975), Expect = e-105, Method: Compositional matrix adjust. Identities = 217/423 (51%), Positives = 282/423 (66%), Gaps = 11/423 (2%) Query: 2 SQTATIAPDRGA-----RSEIETSTIRAISWRLIPFLILAYFFSYLDRVNLGFAALTMNS 56 + T + P GA S E +T R +SWRLIPFL+L Y +YLDRVN+GFA L M + Sbjct: 3 TTTPPLGPSAGALPPQSASGFEEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLN 62 Query: 57 ELKFSPVVFSFGAGIFFIGYFIFEVPSNLALERFGASKWIARIMVSWGILSALMAAVYDE 116 +LKFS V+ GAGIFFIGYF+FEVPSN+ L R GA WIARIM+SWG++SA M V Sbjct: 63 DLKFSETVYGLGAGIFFIGYFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTP 122 Query: 117 HSFYALRFFLGVAEAGFFPGIILYLTYWYPAEYRARFLAAFALAVPISTVIGAPISGLLL 176 FY +RF LG+AEAGFFPGIILYLTYWYPAE R R F AV +S VIG PISG L Sbjct: 123 AMFYVMRFLLGLAEAGFFPGIILYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWAL 182 Query: 177 G-LDGVMGLKGWQWLFVIEGIPSVLLGIVTWFYLTDRPEKAEWLSAEQKAWLKAKLDAEV 235 GV GL GWQW+F+IEGIPSV++G+ YL +R A WL+ E+KA L + AE Sbjct: 183 KTFGGVYGLAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEE 242 Query: 236 AAKQAAKHFTLGEALSSPKVLALSAIYFGFVASLYGMQFWLPQIVKAFGLTNA-QTGFVT 294 A K+ A + ++SP+V +S IYF FV LYG+ FWLP ++K G+ + G +T Sbjct: 243 AQKEDAP---IAAIMASPRVWLMSLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLT 299 Query: 295 AIPYLFGTIAMTLWARRSDATRDRVFHVGAPLLLTALALGVSS-YITDPVMTMVVLTVAA 353 AIPY +AM L AR +D TR+R +H+ P L A+ L +S+ + T+ + M LT+ Sbjct: 300 AIPYGAAVVAMVLVARSADRTRERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGT 359 Query: 354 IGVFCTFAVFWTLPTAWLSGTAAAGAIALINSIGNLAGFGGPYLIGWVKEATGSTSTGLL 413 +G+ T +FW+LPTA+L+GT AA IALINS+GNLAGF PY +GW+K+ T ST +G+ Sbjct: 360 MGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLKDTTRSTDSGMY 419 Query: 414 VLS 416 +L+ Sbjct: 420 LLA 422 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 362 bits (930), Expect = e-100, Method: Compositional matrix adjust. Identities = 195/431 (45%), Positives = 281/431 (65%), Gaps = 6/431 (1%) Query: 1 MSQTATIAPDRGARSEIETSTIRAISWRLIPFLILAYFFSYLDRVNLGFAALTMNSELKF 60 MS+++T + + + + E + R W L+P L+L Y +YLDRVN+GFA L M +L+F Sbjct: 1 MSESSTESLSQPTQLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQF 60 Query: 61 SPVVFSFGAGIFFIGYFIFEVPSNLALERFGASKWIARIMVSWGILSALMAAVYDEHSFY 120 S V+ GAG+FFIGYF E+PSNL L R GA WIARIM++WGI+SA MA V SFY Sbjct: 61 SDTVYGLGAGMFFIGYFFLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFY 120 Query: 121 ALRFFLGVAEAGFFPGIILYLTYWYPAEYRARFLAAFALAVPISTVIGAPISGLLLG-LD 179 +RF LGVAEAGFFPGIILY++YW+P+ R R F ++VP+S +IGAP+SG ++ + Sbjct: 121 VMRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFN 180 Query: 180 GVMGLKGWQWLFVIEGIPSVLLGIVTWFYLTDRPEKAEWLSAEQKAWLKAKLDAEVAAKQ 239 G G GWQW+F++EGIPSVL+GI+ + L DR A WL+ ++K L+ ++ E A Sbjct: 181 GFQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENEAAHY- 239 Query: 240 AAKHFTLGEALSSPKVLALSAIYFGFVASLYGMQFWLPQIVKAFGLTNA-QTGFVTAIPY 298 H L +A P+V L+ IYF ++ Y + FWLP +++ G+ + GF+TAIP Sbjct: 240 --AHSRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPS 297 Query: 299 LFGTIAMTLWARRSDATRDRVFHVGAPLLLTALALGVSSYITDP-VMTMVVLTVAAIGVF 357 + M + +R +D R+R +H+ +L A+ + +S+Y +D V+ MV LT+ A+G Sbjct: 298 AAAAVTMIVVSRSADRLRERRWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGAL 357 Query: 358 CTFAVFWTLPTAWLSGTAAAGAIALINSIGNLAGFGGPYLIGWVKEATGSTSTGLLVLSL 417 T +FW+LPTA+L G+AAA IA INS GNL GF PY++G++K+ T ST+TG+L++S Sbjct: 358 STIPLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAPYMMGYLKDLTQSTTTGMLIIST 417 Query: 418 LPLAAGLLVFL 428 LVFL Sbjct: 418 TLFIGAALVFL 428 >RSp0182 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 453 Score = 358 bits (918), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 181/404 (44%), Positives = 261/404 (64%), Gaps = 9/404 (2%) Query: 8 APDRGARSEIETSTIRAISWRLIPFLILAYFFSYLDRVNLGFAALTMNSELKFSPVVFSF 67 APD E + +R I+WR++PF+ Y SYLDR N+G+AAL MN EL S F F Sbjct: 23 APD-------ERAIVRKITWRILPFVFALYIISYLDRANIGYAALQMNQELALSSEAFGF 75 Query: 68 GAGIFFIGYFIFEVPSNLALERFGASKWIARIMVSWGILSALMAAVYDEHSFYALRFFLG 127 +GIFFIGYF+FEVPSNL L RFGA +WIARI+V+WG+++ A V YALRF LG Sbjct: 76 VSGIFFIGYFLFEVPSNLMLNRFGARRWIARILVTWGLVAMGSAFVQSATQLYALRFLLG 135 Query: 128 VAEAGFFPGIILYLTYWYPAEYRARFLAAFALAVPISTVIGAPISGLLLGLDGVMGLKGW 187 VAEAGFFPGII+YLTYW+ A A +A F A+P+S V+GAP+S ++ + GW Sbjct: 136 VAEAGFFPGIIVYLTYWFRARELATTVALFTAAIPVSYVVGAPLSTWIMDHVHWLQWSGW 195 Query: 188 QWLFVIEGIPSVLLGIVTWFYLTDRPEKAEWLSAEQKAWLKAKLDAEVAAKQAAKHFTLG 247 +W+ ++EG P+V+ G++ + YL DRP+ A WLS ++ WL A+L+ + A+ AA H Sbjct: 196 RWMLLLEGAPAVIGGLLCYGYLADRPKDARWLSEAERDWLLAELERDRKARPAAAHLATL 255 Query: 248 EALSSPKVLALSAIYFGFVASLYGMQFWLPQIVKAF--GLTNAQTGFVTAIPYLFGTIAM 305 + ++ P+VL L+ IYF + G+ +W+PQI+K F L++ + G + +PY+F T M Sbjct: 256 KVMTHPRVLYLAFIYFVYQCGSLGIGYWMPQIIKGFSSALSHTEVGLIAMLPYVFATAVM 315 Query: 306 TLWARRSDATRDRVFHVGAPLLLTALALGVSSYITDPVMTMVVLTVAAIGVFCTFAVFWT 365 W+RRSD +R H PL + ALA + +I P + M +L+++ G++ + FW Sbjct: 316 IWWSRRSDLRAERRLHSAVPLGVAALAFVGAGFIGHPAVAMAMLSLSLAGLYAFKSPFWA 375 Query: 366 LPTAWLSGTAAAGAIALINSIGNLAGFGGPYLIGWVKEATGSTS 409 LPT +L+ + AA +IA+INS+GNL GF GP+ IG+ K ST+ Sbjct: 376 LPTLFLTRSTAAVSIAVINSVGNLGGFVGPFAIGYFKGQMHSTT 419 >AGc4908 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 487 Score = 349 bits (896), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 181/428 (42%), Positives = 270/428 (63%), Gaps = 4/428 (0%) Query: 11 RGARSEI-ETSTIRAISWRLIPFLILAYFFSYLDRVNLGFAALTMNSELKFSPVVFSFGA 69 +G + + E + I I+WRL+PFL L Y +Y+DR N+ +A L M L S + GA Sbjct: 58 KGGKHMVSEKALISKITWRLMPFLGLLYLIAYIDRQNVSYAKLQMVDALSLSEYAYGLGA 117 Query: 70 GIFFIGYFIFEVPSNLALERFGASKWIARIMVSWGILSALMAAVYDEHSFYALRFFLGVA 129 +FFIGYF+FEVPSNL L RFGASKW ARI+VSWG ++ +A + FY LRF LG+ Sbjct: 118 SLFFIGYFLFEVPSNLFLNRFGASKWFARILVSWGAVTIALAYTQNATMFYILRFLLGLC 177 Query: 130 EAGFFPGIILYLTYWYPAEYRARFLAAFALAVPISTVIGAPISGLLLGLDGVMGLKGWQW 189 EAGFFPG++ +T W+P +YR R + F + ++ +GAP+ G+LL LDG +G GW+W Sbjct: 178 EAGFFPGVLFLMTLWFPRDYRGRMIGLFMIFSALANAVGAPLGGMLLDLDGFLGYAGWEW 237 Query: 190 LFVIEGIPSVLLGIVTWFYLTDRPEKAEWLSAEQKAWLKAKLDAEVAAKQAAKHFTLG-E 248 +F+ GIP+V+ GIVT+FYL D P+KA++L+ ++K WLK +L E K +H G + Sbjct: 238 VFLATGIPAVIAGIVTFFYLDDTPDKAKFLTQDEKDWLKNRLAEE--NKGMEEHAEDGFK 295 Query: 249 ALSSPKVLALSAIYFGFVASLYGMQFWLPQIVKAFGLTNAQTGFVTAIPYLFGTIAMTLW 308 AL +P+VL ++ Y GF + YG+ +WLP IVK+FG++N GF+ IP++ IA+ + Sbjct: 296 ALVNPRVLFMALCYVGFPLAAYGLSYWLPTIVKSFGVSNTTNGFINIIPWIIVAIALFVV 355 Query: 309 ARRSDATRDRVFHVGAPLLLTALALGVSSYITDPVMTMVVLTVAAIGVFCTFAVFWTLPT 368 +D +++ ++ P + A L +S+ ++DPV+ L VAA G+F VFW+LP Sbjct: 356 PSAADKAKNKTPYIVGPAFVGAFCLLMSALLSDPVLQFAFLCVAAAGIFAGQPVFWSLPG 415 Query: 369 AWLSGTAAAGAIALINSIGNLAGFGGPYLIGWVKEATGSTSTGLLVLSLLPLAAGLLVFL 428 +L G AA IA INS+GNL GF ++ W+K+ TGST + L+ AG+LV + Sbjct: 416 RFLKGAGAAAGIAAINSVGNLGGFVAQNVVPWIKDQTGSTIAPMFFLAFCLALAGVLVII 475 Query: 429 GSHETKTE 436 + + + Sbjct: 476 ATRKMGNQ 483 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 343 bits (880), Expect = 5e-94, Method: Compositional matrix adjust. Identities = 185/417 (44%), Positives = 273/417 (65%), Gaps = 9/417 (2%) Query: 2 SQTATIAPDRGARSEIETSTIRAISWRLIPFLILAYFFSYLDRVNLGFAALTMNSELKFS 61 S TA +P+ +E T R +++R+IP L++ Y +YLDRVN+GFA L M+ EL FS Sbjct: 22 SNTAITSPE-----VVENMTYRKVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSEELGFS 76 Query: 62 PVVFSFGAGIFFIGYFIFEVPSNLALERFGASKWIARIMVSWGILSALMAAVYDEHSFYA 121 ++ GAG+FFIGYF FE+PSN+ L + GA WIARIM++WG+LSAL A V E FY Sbjct: 77 EAIYGLGAGLFFIGYFFFEIPSNILLHKLGARLWIARIMITWGLLSALFAFVQTEWQFYI 136 Query: 122 LRFFLGVAEAGFFPGIILYLTYWYPAEYRARFLAAFALAVPISTVIGAPISGLLLG-LDG 180 LRF LG AEAGF+PG+ILYLTYW+P+ R A F P + + G P+SG ++ Sbjct: 137 LRFLLGAAEAGFYPGVILYLTYWFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIMDQFHD 196 Query: 181 VMGLKGWQWLFVIEGIPSVLLGIVTWFYLTDRPEKAEWLSAEQKAWLKAKLDAEVAAKQA 240 G +GWQW+FV+E IP+V+LG+V YL + + A+WL+ E+KA + ++A+ K A Sbjct: 197 TAGWQGWQWMFVLEAIPAVVLGVVILLYLDNSVKAAKWLTEEEKAIISRDIEADSKGK-A 255 Query: 241 AKHFTLGEALSSPKVLALSAIYFGFVASLYGMQFWLPQIVKAFGLT-NAQTGFVTAIPYL 299 A H +L + +P + + IYF FV +G+ W+P +++A G+T N G + AIP++ Sbjct: 256 ASH-SLMSLVKNPMLWVMMLIYFCFVMGQHGLTLWMPTLIRASGVTSNVTIGLLGAIPFI 314 Query: 300 FGTIAMTLWARRSDATRDRVFHVGAPLLLTALALGVSSYITDPVMTMVVLTVAAIGVFCT 359 IAM +++R +D R+R +H+ P LL A+ V++ T+ ++++ L++AA GV Sbjct: 315 CAIIAMVIFSRSADHYRERRWHLVVPALLGAVGFVVAASATNTTVSIIFLSMAAAGVLAC 374 Query: 360 FAVFWTLPTAWLSGTAAAGAIALINSIGNLAGFGGPYLIGWVKEATGSTSTGLLVLS 416 +FW+LPTA LSG AAA IALINS+ NLAGF PY++G +++AT S+ G+ VL+ Sbjct: 375 APLFWSLPTAILSGAAAAAGIALINSVANLAGFISPYMVGIIRDATHSSELGMYVLA 431