BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0059.0218.p         (333 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BMEII0136 [E] COG0346 Lactoylglutathione lyase and related lyase...   277   2e-74
DRA0224 [E] COG0346 Lactoylglutathione lyase and related lyases ...   211   2e-54
SSO2054 [E] COG0346 Lactoylglutathione lyase and related lyases ...   165   1e-40

>BMEII0136 [E] COG0346 Lactoylglutathione lyase and related lyases Bme
           Brucella melitensis
          Length = 331

 Score =  277 bits (709), Expect = 2e-74,   Method: Compositional matrix adjust.
 Identities = 135/324 (41%), Positives = 190/324 (58%)

Query: 3   MSLRITNHDPGFRITRASHVVLTVRDLAASRQFYEKVIGLILTAEEGGALYFRGVEEACH 62
           M L   N  P F I R SHV L V DL  SR FY   +GL +T E   A+Y R +EE  H
Sbjct: 6   MPLPTPNLHPPFNIVRLSHVELGVTDLTKSRAFYVDTLGLQVTDESADAIYLRALEERGH 65

Query: 63  HSLVLRKGEGAACARLGLRVFQDEDLDRLKAFFEAHGCRAAWAEVPHQGRTLHATDPAGT 122
           H +VLRK + A    LG +++ ++D DR + FF+  G    W E P+Q RTL   DP G 
Sbjct: 66  HCIVLRKTDKAEARDLGFKLYSEDDFDRAEHFFKGKGLPVEWVERPYQSRTLRTRDPHGI 125

Query: 123 PLEFCATMPVEPRMITKFTRHAGGSALRLDHYQVLTPEVRKACEFYTAAGFRLSEYIAPA 182
           PLEF + M   P +  K+  + G   LR+DH+   +P V ++  FY   GFR++EY   A
Sbjct: 126 PLEFYSRMDRLPPIHQKYALYKGVKPLRIDHFNCFSPNVDESVAFYNELGFRVTEYTEDA 185

Query: 183 DTFDLRGAFLQRKGNPHDIVFFNGAGPRLHHFAFLAPEVHHLLNACDIAGELGYGASVER 242
           +T  L  A+  RKG  HDI F NG GPRLHH AF  P   ++++  D+    G+ A++ER
Sbjct: 186 ETGRLWAAWTHRKGGVHDITFTNGKGPRLHHTAFWVPTPLNIIDLLDLMSTTGWLANIER 245

Query: 243 GPGRHGPGHAMYVYMRDPDGHRVELFNTHYQIMDIENEPVAWDPSDHKISFPWGLPARQA 302
           GPGRHG  +A ++Y+RDPDGHR+E++ + YQ +D + EP+ WD  D +    WG PA ++
Sbjct: 246 GPGRHGISNAFFLYVRDPDGHRIEIYCSDYQTVDPDLEPIKWDLKDPQRQTLWGAPAPKS 305

Query: 303 WFDEATPFEGVAIREPQMKPKPLT 326
           WF+E + F  V   +  +K +P+ 
Sbjct: 306 WFEEGSLFASVQPVDSVLKAQPIV 329


>DRA0224 [E] COG0346 Lactoylglutathione lyase and related lyases Dra
           Deinococcus radiodurans
          Length = 340

 Score =  211 bits (536), Expect = 2e-54,   Method: Compositional matrix adjust.
 Identities = 116/300 (38%), Positives = 165/300 (55%), Gaps = 6/300 (2%)

Query: 16  ITRASHVVLTVRDLAASRQFYEKVIGLILTAEEGGALYFRGVEEACHHSLVL---RKGEG 72
           I R +  V TV DL ASR+FY  ++G+ +  EE GALY RGVE+    +L L   R+GE 
Sbjct: 21  IIRIAQAVFTVSDLNASREFYVDLLGMNVLHEESGALYLRGVEDR-EWTLKLEQCREGEL 79

Query: 73  AACARLGLRVFQDEDLDRLKAFFEAHGCRAAWAEVPHQGRTLHATDPAGTPLEFCATMPV 132
                LG RV  +  LD L A  +A G    W E   + R L   DP G PL F   +  
Sbjct: 80  PRVRHLGYRVRDEASLDTLLALADAQGLPHRWEEELDRPRMLRMQDPFGIPLAFYLEVKT 139

Query: 133 EPRMITKFTRHAGGSALRLDHYQVLTPEVRKACEFYTAA-GFRLSEYIAPADTFDLRGAF 191
            P ++  + +H G    R+DH  V  P+V+   ++Y A  GFR+SEY    +      A+
Sbjct: 140 YPWLLQNYHQHRGPGLQRVDHCNVRVPDVKATLDWYGAELGFRVSEYTV-DEQEQYWAAW 198

Query: 192 LQRKGNPHDIVFFNGAGPRLHHFAFLAPEVHHLLNACDIAGELGYGASVERGPGRHGPGH 251
           +QR+G  HD    NGAGP LHH+A+  P+   ++  CDI         +ERGPGRHG  +
Sbjct: 199 IQRRGGVHDFALTNGAGPCLHHWAYWMPDAMSIIKTCDILAGARMPERIERGPGRHGVSN 258

Query: 252 AMYVYMRDPDGHRVELFNTHYQIMDIENEPVAWDPSDHKISFPWGLPARQAWFDEATPFE 311
           A ++Y+RDPDGHR+EL+ + Y  +D + EP+ W   D +    WG    ++WF++A+P E
Sbjct: 259 AFFLYIRDPDGHRIELYTSDYITVDPDFEPIRWLRDDPRRQTLWGAKTPRSWFEDASPLE 318


>SSO2054 [E] COG0346 Lactoylglutathione lyase and related lyases Sso
           Sulfolobus solfataricus
          Length = 316

 Score =  165 bits (418), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 95/303 (31%), Positives = 150/303 (49%), Gaps = 8/303 (2%)

Query: 18  RASHVVLTVRDLAASRQFYEKVIGLILTAEEGGALYFRGVEEACHHSLVLRKGEGAACAR 77
           R SHV + V DL  +R FY +++G + T ++G  +Y RG+EE  HHSL+L+K   A  + 
Sbjct: 7   RTSHVCIRVSDLDKARYFYSELLGFVETEKDGDYIYLRGIEEGQHHSLILKKANSAGLSY 66

Query: 78  LGLRVFQDEDLDRLKAFFEAHGCRAAWAEVPHQGRTLHATDPAGTPLEFCATMPVEPRMI 137
           +G RV + E+LD+ +   E  G +            L    P G P+     M     + 
Sbjct: 67  IGFRVSKGEELDKAREELENLGHKVRKFREKGINEALLFESPEGIPILLYYDMEYVGDLR 126

Query: 138 TKFTRHAGGSALRLDHYQVLTPEVRKACEFYTA-AGFRLSEYIAPADTFDLRGAFLQRKG 196
             F RH G S +RL H   +  ++ +  EF+    G+  +E     D  +L   +L R+G
Sbjct: 127 LAFHRHRGVSPVRLAHVNYMVKDLERELEFFKRFMGYYETERFLDKDG-NLAVVWLTRRG 185

Query: 197 NPHDIVFFNGAG--PRLHHFAFLAPEVHHLLNACDIAGELGYGASVERGPGRHGPGHAMY 254
           + H+I     +   P  HH  +   +V  ++ A DI   +G   S+ERGPGRHG     Y
Sbjct: 186 DSHEIAIAKSSKNVPGFHHETYYVHDVKDVIKAPDILASVGLWDSIERGPGRHGVTEGYY 245

Query: 255 VYMRDPDGHRVELFNTHYQIMDIEN-EPVAW--DPSDHKISFPWGLPARQAWFDEATPFE 311
           +Y+RD D +R+E F   Y ++D +  +P+ W  D   ++  F WG P  Q+W  E    E
Sbjct: 246 IYLRDFDKNRIEFFTNDYVVLDPDKWKPIVWTYDQLRYRSDF-WGRPIPQSWLTEWVAVE 304

Query: 312 GVA 314
            ++
Sbjct: 305 DIS 307