BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0059.0206.p (270 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC2712 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Cac ... 160 3e-39 AF2273_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu... 155 1e-37 PAE2479 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pya ... 150 4e-36 BS_yngF [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bsu ... 146 5e-35 FN1020 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Fnu F... 144 2e-34 >CAC2712 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Cac Clostridium acetobutylicum Length = 261 Score = 160 bits (405), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 93/250 (37%), Positives = 142/250 (56%), Gaps = 3/250 (1%) Query: 22 VGVITFNNPDKRNAMSLEMWEGLGEALTTLRDDPAVRVVILVGAGDKAFVSGADISQFEK 81 V V+T N P NA++ + + + + + +D V VIL GAG+K+FV+GADIS+ ++ Sbjct: 14 VAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSFVAGADISEMKE 73 Query: 82 TRHNAEASEEYSRRSAAQRALLADYPKPTIACIRGFCLGGGMQVAMLTDIRISGSSGQFG 141 N ++ L KP IA + GF LGGG ++AM DIRI+ S+ +FG Sbjct: 74 --MNTIEGRKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSCDIRIASSNARFG 131 Query: 142 IPAAKLGIAYGYDGLRHLVSLVGPSWARLIMYTGMRIDSAEALRIGLVDRVLPDAELWDA 201 P LGI G+ G + L LVG A+ +++T I + EALRIGLV++V+ +EL + Sbjct: 132 QPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLVNKVVEPSELMNT 191 Query: 202 TMEIARTISGNAPLAIKAAKITIAQALKDPADRDMAAIKQIGIECMDSADFREGRSAFME 261 EIA I NAP+A+K +K I + ++ D +A + EC + D ++ +AF+E Sbjct: 192 AKEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFESEAFGECFSTEDQKDAMTAFIE 251 Query: 262 KRKPQ-FKGR 270 KRK + FK R Sbjct: 252 KRKIEGFKNR 261 >AF2273_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu Archaeoglobus fulgidus Length = 262 Score = 155 bits (391), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 98/265 (36%), Positives = 143/265 (53%), Gaps = 31/265 (11%) Query: 21 GVGVITFNNPDKRNAMSLEMWEGLGEALTTLRDDPAVRVVILVGAGDKAFVSGADI---- 76 G+ + N PD+ N +S E+ + + A+T L +D RV+++ GAGD+AF +GAD+ Sbjct: 14 GITKLVLNRPDRLNTISPEVLDEIDRAITQLWNDKDTRVIVITGAGDRAFSAGADLGGSI 73 Query: 77 --SQFEKTRHNAEASEEYSRRSAAQRALLADYPKPTIACIRGFCLGGGMQVAMLTDIRIS 134 F+ HN + ++R L + PKP IA I G+ LGGG+++AM DIR++ Sbjct: 74 ITHPFDFLEHNRKGERVFTR--------LREIPKPVIAAINGYALGGGLEIAMNCDIRLA 125 Query: 135 GSSGQFGIPAAKLGIAYGYDGLRHLVSLVGPSWARLIMYTGMRIDSAEALRIGLVDRVLP 194 S G+P LGI G+ G + LV LVG S A + TG RI + EA R GLV++V Sbjct: 126 KKSAVLGLPEVGLGILPGWSGTQRLVKLVGISRAMQLALTGERITAEEAERWGLVNKVFD 185 Query: 195 DAELWDATMEIARTISGN-APLAIKAAKITIAQALKDPADRDMAAIKQIGIECMDSA--- 250 D + + M A+ I+ AP+++ K I + + P D IG+E +A Sbjct: 186 DDKFEEEVMNYAKNIAERCAPISMALIKRLINKGGEVPMD--------IGLEWECTAAGL 237 Query: 251 -----DFREGRSAFMEKRKPQFKGR 270 D REG SAF+ K KPQFKGR Sbjct: 238 LFATEDMREGISAFLRKDKPQFKGR 262 >PAE2479 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pya Pyrobaculum aerophilum Length = 282 Score = 150 bits (378), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 95/270 (35%), Positives = 145/270 (53%), Gaps = 10/270 (3%) Query: 1 MPNMSNKSLADGKI-LQDVVDGVGVITFNNPDKRNAMSLEMWEGLGEALTTLRDDPAVRV 59 +P+M + A GKI L+ V +G+ + N P++ N ++LEM +GEAL L A RV Sbjct: 21 VPHM--REYAGGKIRLEQVEEGIYQLLINYPERLNIITLEMRRAIGEALGDLLKTEA-RV 77 Query: 60 VILVGAGDKAFVSGADISQFEKTRHNAEASEEYSRRSAAQRALLADYPKPTIACIRGFCL 119 +I+ AGD+AF +G D+ +F KT L + P PTIA ++G+ L Sbjct: 78 LIVASAGDRAFSAGGDMGEFLKTTTTDLLD------WGKTLVELEELPIPTIAELKGYVL 131 Query: 120 GGGMQVAMLTDIRISGSSGQFGIPAAKLGIAYGYDGLRHLVSLVGPSWARLIMYTGMRID 179 GGG+++A+ DIRI+ ++ G+P +LG+ GL V +GP A+ + G R+ Sbjct: 132 GGGLELALSCDIRIASTNAVIGLPEVRLGMVPASGGLTRFVKALGPLRAKYYILLGKRMT 191 Query: 180 SAEALRIGLVDRVLPDAELWDATMEIARTISGNAPLAIKAAKITIAQALKDPADRDMAAI 239 + EAL++GLVD V+P L +EIAR + PLA+K AK ++ P + Sbjct: 192 AEEALKLGLVDEVVPPEGLRGRVLEIARELRELPPLALKEAKKLVSMIADAPREVGFDLE 251 Query: 240 KQIGIECMDSADFREGRSAFMEKRKPQFKG 269 ++ S DF EG AF EKR+P + G Sbjct: 252 RKTFGVLRYSRDFEEGIKAFFEKRRPNYTG 281 >BS_yngF [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bsu Bacillus subtilis Length = 260 Score = 146 bits (368), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 89/252 (35%), Positives = 137/252 (54%), Gaps = 6/252 (2%) Query: 20 DGVGVITFNNPDKRNAMSLEMWEGLGEALTTLRDDPAVRVVILVGAGDKAFVSGADISQF 79 + + +IT N P NA+S EM L + + + +R VIL G G+KAF +GAD+ + Sbjct: 12 EHMALITLNRPQAANALSAEMLRNLQMIIQEIEFNSNIRCVILTGTGEKAFCAGADLKER 71 Query: 80 EKTRHNAEASEEYS--RRSAAQRALLADYPKPTIACIRGFCLGGGMQVAMLTDIRISGSS 137 K + + + E S +R+AA LL P+P IA I G LGGG+++A+ D+RI+ + Sbjct: 72 IKLKED-QVLESVSLIQRTAA---LLDALPQPVIAAINGSALGGGLELALACDLRIATEA 127 Query: 138 GQFGIPAAKLGIAYGYDGLRHLVSLVGPSWARLIMYTGMRIDSAEALRIGLVDRVLPDAE 197 G+P L I G G + L L+G A+ +YTG R+ + EA IGLV+ V + Sbjct: 128 AVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIYTGRRVTAHEAKEIGLVEHVTAPCD 187 Query: 198 LWDATMEIARTISGNAPLAIKAAKITIAQALKDPADRDMAAIKQIGIECMDSADFREGRS 257 L E+A IS N P+A++ AK I + L+ +A ++ + + + D REG Sbjct: 188 LMPKAEELAAAISANGPIAVRQAKFAINKGLETDLATGLAIEQKAYEQTIPTKDRREGLQ 247 Query: 258 AFMEKRKPQFKG 269 AF EKR+ +KG Sbjct: 248 AFQEKRRAVYKG 259 >FN1020 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Fnu Fusobacterium nucleatum Length = 258 Score = 144 bits (363), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 81/243 (33%), Positives = 132/243 (54%), Gaps = 3/243 (1%) Query: 22 VGVITFNNPDKRNAMSLEMWEGLGEALTTLRDDPAVRVVILVGAGDKAFVSGADISQFEK 81 +G++T P+ NA++ ++ + L + + RVV+L G+G K+FV+GADI+ E Sbjct: 12 IGIVTIERPEALNALNSQVLDELSATFAGINLE-TTRVVLLTGSGSKSFVAGADIA--EM 68 Query: 82 TRHNAEASEEYSRRSAAQRALLADYPKPTIACIRGFCLGGGMQVAMLTDIRISGSSGQFG 141 + N++ ++ + + +P P IA I GF LGGG ++AM D RI + FG Sbjct: 69 STLNSDEGTKFGYKGNEIFRKIETFPLPVIAVINGFALGGGCELAMSCDFRICSENAIFG 128 Query: 142 IPAAKLGIAYGYDGLRHLVSLVGPSWARLIMYTGMRIDSAEALRIGLVDRVLPDAELWDA 201 P LGI G+ G + L L+G A+ ++YT I + EAL IGLV+ V P L + Sbjct: 129 QPEVGLGITPGFGGTQRLARLIGLGKAKEMIYTANTIKADEALNIGLVNHVYPQETLMEE 188 Query: 202 TMEIARTISGNAPLAIKAAKITIAQALKDPADRDMAAIKQIGIECMDSADFREGRSAFME 261 M++A I+ NAP A++A K I + + DR + +++ C + D + G AF++ Sbjct: 189 AMKLAGKIAKNAPFAVRACKKAINEGIDTDMDRAIIIEEKLFGSCFATEDQKVGMKAFLD 248 Query: 262 KRK 264 K K Sbjct: 249 KVK 251