BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0059.0197.p (341 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll0103 [BQ] COG0123 Deacetylases, including yeast histone deace... 375 e-104 PA1409 [BQ] COG0123 Deacetylases, including yeast histone deacet... 290 2e-78 PA0321 [BQ] COG0123 Deacetylases, including yeast histone deacet... 272 7e-73 mlr2893 [BQ] COG0123 Deacetylases, including yeast histone deace... 254 2e-67 mlr6968 [BQ] COG0123 Deacetylases, including yeast histone deace... 240 3e-63 >mll0103 [BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein Mlo Mesorhizobium loti Length = 342 Score = 375 bits (963), Expect = e-104, Method: Compositional matrix adjust. Identities = 189/337 (56%), Positives = 237/337 (70%) Query: 1 VKAVYSDLHRSHDPQFFLVRGVVQRTTEQPERADRLLAGLKAGKHTLIEPTRFGQGPRAR 60 +KA Y++ + HDP+ FL G Q E+PER ++LLAG K+ + +P G GP + Sbjct: 1 MKAFYAEEQKRHDPKAFLSSGAAQPNPEKPERVEKLLAGAKSAGCMIEQPRNHGLGPVSA 60 Query: 61 VHSPEYLSFLADAWDEWSALGNAGPEMIANIHPVRNAGTYPAHIVGKLGWHTMDTAAPIG 120 VH+PEYL FL ++ W + A E+I NIHP+ G+YPA VG+ G+H DTA PI Sbjct: 61 VHTPEYLDFLEHIFERWQRIEGASAEVIPNIHPIARNGSYPASAVGQAGYHMADTACPIS 120 Query: 121 PGTWAGACAASDVAVSAAQMVLDGEDAVYALCRPPGHHAYRDLAGGFCFLNNSAIAAEHL 180 TW A ++ AV AA+ V+ G A YALCRPPGHHA+ D+AGGFCF+NNSA+AA+ L Sbjct: 121 GETWQSALWSAWSAVEAAEAVMAGAPAAYALCRPPGHHAFADVAGGFCFINNSAVAAQVL 180 Query: 181 RQKHERVAILDVDVHHGNGTQGIFYERGDVFTVSIHADPSFFYPFVWGHAHERGAGGGLG 240 R++ RVAILDVD+HHGNGTQGIFY R DVFTVS+HADP FYPF WGHA ERG G GLG Sbjct: 181 RKQAARVAILDVDLHHGNGTQGIFYARPDVFTVSLHADPVRFYPFFWGHADERGEGPGLG 240 Query: 241 TNLNIPLAKGTGDDDYMKALAAAEKAIRSFAPTALVVALGLDASEKDPLAGLAVTTGGFR 300 N N+PL + + D +++AL A + IR+F+P ALVVALGLDA E DP GL+VTT GF Sbjct: 241 YNFNLPLPRKSADAAFLEALGVAFQRIRAFSPDALVVALGLDAFEGDPFGGLSVTTPGFS 300 Query: 301 RIGEGLARFGLPTVLVQEGGYLSDILGANLTAVLGGF 337 RIGE + + GLP+V+VQEGGYL D L NLTA L GF Sbjct: 301 RIGEAIGKLGLPSVVVQEGGYLCDALSDNLTAFLTGF 337 >PA1409 [BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein Pae Pseudomonas aeruginosa Length = 346 Score = 290 bits (743), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 157/343 (45%), Positives = 213/343 (62%), Gaps = 6/343 (1%) Query: 3 AVYSDLHRSHDPQFFLVRGVVQRTTEQPERADRLLAGLKAGK-HTLIEPTRFGQGPRARV 61 +VYSD HR H Q LV G +Q E P RAD +LA +K+ +I P FG+ P R+ Sbjct: 3 SVYSDDHRLHFGQSELVDGKLQPCFEMPSRADTVLARVKSQNLGEVIAPKDFGREPLLRL 62 Query: 62 HSPEYLSFLADAWDEWSALGNAGPEMIANIHP---VRNAGTYPAHIVGKLGWHTMDTAAP 118 H YL FL AW W+A G++G ++++ P +R G P ++G+LG+++ DT AP Sbjct: 63 HDAAYLDFLQGAWARWTAEGHSG-DLVSTTFPGRRLRRDGPIPTALMGELGYYSFDTEAP 121 Query: 119 IGPGTWAGACAASDVAVSAAQMVLDGEDAVYALCRPPGHHAYRDLAGGFCFLNNSAIAAE 178 I GTW +++ VA++A + + G + +ALCRPPGHHA D GG+CFLNN+AIA + Sbjct: 122 ITAGTWQAIYSSAQVALTAQEHMRQGARSAFALCRPPGHHAGGDFMGGYCFLNNAAIATQ 181 Query: 179 -HLRQKHERVAILDVDVHHGNGTQGIFYERGDVFTVSIHADPSFFYPFVWGHAHERGAGG 237 L Q RVAILDVD HHGNGTQ IFY R DV SIH DP YP+ G+A ERG G Sbjct: 182 AFLDQGARRVAILDVDYHHGNGTQDIFYRRDDVLFASIHGDPRVEYPYFLGYADERGEGA 241 Query: 238 GLGTNLNIPLAKGTGDDDYMKALAAAEKAIRSFAPTALVVALGLDASEKDPLAGLAVTTG 297 G G N N PLA G+G D + AL A I +AP ALV++LG+D ++DP++ + + Sbjct: 242 GEGCNHNYPLAHGSGWDLWSAALDDACVRIAGYAPDALVISLGVDTYKEDPISQFRLDSP 301 Query: 298 GFRRIGEGLARFGLPTVLVQEGGYLSDILGANLTAVLGGFEAA 340 + R+GE +AR GLPT+ + EGGY + +G N VL G+E A Sbjct: 302 DYLRMGERIARLGLPTLFIMEGGYAVEAIGINAVNVLQGYEGA 344 >PA0321 [BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein Pae Pseudomonas aeruginosa Length = 344 Score = 272 bits (696), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 148/338 (43%), Positives = 208/338 (61%), Gaps = 4/338 (1%) Query: 4 VYSDLHRSHDPQFFLVRGVVQRTTEQPERADRLLAGLKA-GKHTLIEPTRFGQGPRARVH 62 +YSD HR H + L+ G E+P RAD +L +KA G + P FG P RVH Sbjct: 4 IYSDDHRLHHGRHELIGGQFTPCFEKPSRADMVLDRVKAVGLGEVRAPRDFGLEPIRRVH 63 Query: 63 SPEYLSFLADAWDEWSALGNAGPEMIANIHPVRNA-GTYPAHIVGKLGWHTMDTAAPIGP 121 S ++ FL +AW +W A G + +M+ P R T P +I G+LG+++ D API Sbjct: 64 SEGFVRFLQNAWQDWLATGRS-HDMLPIAWPTRRLRQTEPDNIDGRLGYYSFDAGAPITA 122 Query: 122 GTWAGACAASDVAVSAAQMVLDGEDAVYALCRPPGHHAYRDLAGGFCFLNNSAIAAE-HL 180 GTW ++++VA+S + +G +V++LCRPPGHHA D GG+CF NN+AIAA+ L Sbjct: 123 GTWQAITSSANVALSGQSELANGARSVFSLCRPPGHHAAADYMGGYCFFNNAAIAAQAFL 182 Query: 181 RQKHERVAILDVDVHHGNGTQGIFYERGDVFTVSIHADPSFFYPFVWGHAHERGAGGGLG 240 + RVAILDVD HHGNGTQ IFY+R DV SIH DP F YP+ G+A E+G G G G Sbjct: 183 DRGAGRVAILDVDYHHGNGTQDIFYDRADVLFTSIHGDPRFEYPYFLGYADEKGNGVGTG 242 Query: 241 TNLNIPLAKGTGDDDYMKALAAAEKAIRSFAPTALVVALGLDASEKDPLAGLAVTTGGFR 300 N N PLA G+ + +AL AA + I+++A AL+V+LG+D ++DP++ + + + Sbjct: 243 YNFNYPLAAGSDWATWSQALQAAIRQIQAYAADALIVSLGVDTFKEDPISQFRLDSPDYL 302 Query: 301 RIGEGLARFGLPTVLVQEGGYLSDILGANLTAVLGGFE 338 R+GE + + GL T+ V EGGY + +G N VL GFE Sbjct: 303 RMGEAIGKLGLATLFVMEGGYAVEEIGINAVNVLQGFE 340 >mlr2893 [BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein Mlo Mesorhizobium loti Length = 343 Score = 254 bits (650), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 139/342 (40%), Positives = 200/342 (58%), Gaps = 5/342 (1%) Query: 1 VKAVYSDLHRSHDPQFFLVRGVVQRTTEQPERADRLLAGLKAGKH-TLIEPTRFGQGPRA 59 +K VYS LH H Q LV + E+P RA+ + A +++ ++ P Sbjct: 1 MKTVYSPLHAGHAGQMELVTSAIVPGFEKPSRAEFIKARVESENLGPIVLPLEHDLAAAK 60 Query: 60 RVHSPEYLSFLADAWDEWSALGNAGPEMIANIHPVR--NAGTYPAHIVGKLGWHTMDTAA 117 R+H +Y+ FL W +W A G+ G M P R P + LG+++ D A Sbjct: 61 RIHKSDYVDFLPTVWPQWVASGHEGTAM-PFTWPTRGLRGDVPPKRVDALLGYYSFDAGA 119 Query: 118 PIGPGTWAGACAASDVAVSAAQMVLDGEDAVYALCRPPGHHAYRDLAGGFCFLNNSAIAA 177 GTWA ++ DVA++AA +V GE + +ALCRPPGHHA GG+C++NN+A+AA Sbjct: 120 TFVEGTWAAIKSSYDVALTAAGLVKGGERSAFALCRPPGHHAGAGFMGGYCYINNAAVAA 179 Query: 178 E-HLRQKHERVAILDVDVHHGNGTQGIFYERGDVFTVSIHADPSFFYPFVWGHAHERGAG 236 + L Q +R++ILDVD HHGNGTQ IFY+R DV +++H DP YPF GHA ERGAG Sbjct: 180 QWFLDQGAKRISILDVDYHHGNGTQEIFYDRADVQVLNLHGDPLVEYPFFLGHADERGAG 239 Query: 237 GGLGTNLNIPLAKGTGDDDYMKALAAAEKAIRSFAPTALVVALGLDASEKDPLAGLAVTT 296 G G N+N P+ GT D + +L A + ++AP ++V+LG+D EKDP++ +T+ Sbjct: 240 DGEGFNINYPMPFGTDWDAWNASLEDACGKLAAYAPDIVIVSLGVDTFEKDPISQFKLTS 299 Query: 297 GGFRRIGEGLARFGLPTVLVQEGGYLSDILGANLTAVLGGFE 338 + +IG +A+ GLPT+ V EGGY + +G N VL GFE Sbjct: 300 PDYPKIGRRIAKLGLPTLFVMEGGYAVEEIGINAVGVLTGFE 341 >mlr6968 [BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein Mlo Mesorhizobium loti Length = 346 Score = 240 bits (613), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 139/346 (40%), Positives = 192/346 (55%), Gaps = 9/346 (2%) Query: 1 VKAVYSDLHRSHDPQFFLVRGVVQRTTEQPERADRLLAGLKAGK-HTLIEPTRFGQGPRA 59 +K ++S + H QF G V E RA + + ++ + ++ P Sbjct: 1 MKTIFSPIQLKHQGQFEFYNGAVVEGYENTSRATFITSRIEEVRLGPVLNPRPQSLDTAK 60 Query: 60 RVHSPEYLSFLADAWDEWSALGNAGPEMIANIHPVRNAGTY----PAHIVGKLGWHTMDT 115 R+HSP YL F+A AW W G G + P R G Y P I +LG +++D Sbjct: 61 RIHSPTYLDFIASAWRLWRDAGRTGTAL-PYAWPAR--GRYKDVAPDSIDAQLGQYSIDA 117 Query: 116 AAPIGPGTWAGACAASDVAVSAAQMVLDGEDAVYALCRPPGHHAYRDLAGGFCFLNNSAI 175 + GTW A+ D A++AA ++++GE A +ALCRPPGHHA D GG+CF+NN+A+ Sbjct: 118 STGFVEGTWEAVKASHDSALTAADLIIEGEQACFALCRPPGHHAGTDFNGGYCFVNNAAV 177 Query: 176 AAEHLRQK-HERVAILDVDVHHGNGTQGIFYERGDVFTVSIHADPSFFYPFVWGHAHERG 234 AA+ L RV ILD+D HHGNGTQ IFY RGDV VS+HADP YPF G+A ERG Sbjct: 178 AAQRLLDGGASRVTILDIDYHHGNGTQEIFYARGDVQVVSLHADPRNDYPFFAGYADERG 237 Query: 235 AGGGLGTNLNIPLAKGTGDDDYMKALAAAEKAIRSFAPTALVVALGLDASEKDPLAGLAV 294 +G G G N+NIPL GT + AL A ++R F P +V++ G+D E DP++ + Sbjct: 238 SGSGEGFNINIPLPHGTDWAQWEGALDFALGSVRQFGPDVVVISHGVDTFEGDPISRFRL 297 Query: 295 TTGGFRRIGEGLARFGLPTVLVQEGGYLSDILGANLTAVLGGFEAA 340 + F IG LA T+ V EGGY + +G N+ VL G+E A Sbjct: 298 SHDHFPLIGARLAGLQTKTLFVLEGGYAVEDVGINVVGVLSGYEDA 343