BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0059.0192.p (338 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ycbE [GEPR] COG0477 Permeases of the major facilitator superf... 385 e-107 RSp0828 [GEPR] COG0477 Permeases of the major facilitator superf... 378 e-104 STM2962 [GEPR] COG0477 Permeases of the major facilitator superf... 365 e-101 ygcZ [GEPR] COG0477 Permeases of the major facilitator superfami... 365 e-100 Z4105 [GEPR] COG0477 Permeases of the major facilitator superfam... 363 e-100 >BS_ycbE [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 455 Score = 385 bits (990), Expect = e-107, Method: Compositional matrix adjust. Identities = 176/267 (65%), Positives = 214/267 (80%), Gaps = 2/267 (0%) Query: 1 MLFLVTTVNYADRATLSIAGPALSKELHLDPVAMGYVFSAFGWSYAVAQVPCGWLLDRFG 60 MLFLVT++NYADRATLSI G ++ +L LD VAMGYVFSAFGW+Y + Q+P GWLLDRFG Sbjct: 24 MLFLVTSINYADRATLSITGDSVQHDLGLDSVAMGYVFSAFGWAYVIGQLPGGWLLDRFG 83 Query: 61 SKWVYALSIIVWSIFTAMQGLVGFLSAGAAVVLLFGLRFLVGIAEAPSFPANARIVASWF 120 SK + ALSI WS FT +QG +GF SAG A++LLF LRFLVG++EAPSFP N R+VASWF Sbjct: 84 SKTIIALSIFFWSFFTLLQGAIGFFSAGTAIILLFALRFLVGLSEAPSFPGNGRVVASWF 143 Query: 121 PGNERGTASAFFNSGQYFATVIFAPLMGWIAHEYGWRHVFYVMGALGIVMGIAWIKTIYE 180 P +ERGTASAFFNS QYFA VIF PLMGW+ H +GW VF VMG GI++ + W+KT+YE Sbjct: 144 PSSERGTASAFFNSAQYFAIVIFPPLMGWLTHSFGWHSVFVVMGIAGILLAVIWLKTVYE 203 Query: 181 PKEHPAINEAEFDYIKQGGALVDMDATKDGKAHDGGPRWDHIRQLLANRMMLGVYIGQYC 240 PK+HP +NEAE YI+QGG L+ MD +K + + +W +I+QLL NRM++GVYI QYC Sbjct: 204 PKKHPKVNEAELAYIEQGGGLISMDDSKSKQETES--KWPYIKQLLTNRMLIGVYIAQYC 261 Query: 241 INTLTYFFLTWFPVYLVKERGLSILXA 267 I TLTYFFLTWFPVYLV+ RG+SIL A Sbjct: 262 ITTLTYFFLTWFPVYLVQARGMSILEA 288 >RSp0828 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 450 Score = 378 bits (971), Expect = e-104, Method: Compositional matrix adjust. Identities = 172/267 (64%), Positives = 219/267 (82%), Gaps = 2/267 (0%) Query: 1 MLFLVTTVNYADRATLSIAGPALSKELHLDPVAMGYVFSAFGWSYAVAQVPCGWLLDRFG 60 MLF+VTT+NYADRAT+S+AG A+ K+L +D V++GY+FSAFGW+Y +AQ+P GWLLDRFG Sbjct: 29 MLFIVTTINYADRATISMAGSAMQKDLGIDAVSLGYIFSAFGWAYVIAQIPGGWLLDRFG 88 Query: 61 SKWVYALSIIVWSIFTAMQGLVGFLSAGAAVVLLFGLRFLVGIAEAPSFPANARIVASWF 120 S+ VY+ SI++WS+FT MQG +GF + AA+VL+F LRF+VG+AEAPSFPAN+RIVA+WF Sbjct: 89 SRRVYSFSILLWSLFTLMQGTIGFFTGMAAIVLVFFLRFMVGVAEAPSFPANSRIVAAWF 148 Query: 121 PGNERGTASAFFNSGQYFATVIFAPLMGWIAHEYGWRHVFYVMGALGIVMGIAWIKTIYE 180 P NERGTASA FNS QY ATVIFAPLM W+ H +GW +VF VMG +GIVM +AW + +++ Sbjct: 149 PANERGTASAIFNSAQYAATVIFAPLMAWLVHAFGWHYVFIVMGVIGIVMALAWKRFMHD 208 Query: 181 PKEHPAINEAEFDYIKQGGALVDMDATKDGKAHDGGPRWDHIRQLLANRMMLGVYIGQYC 240 PK+HP I AE +YI+ GG LV+MD + G A GP +I+QLL NRM++GVYI QYC Sbjct: 209 PKDHPRITRAEIEYIEAGGGLVNMD--RAGVAKTEGPDMGYIKQLLRNRMLMGVYIAQYC 266 Query: 241 INTLTYFFLTWFPVYLVKERGLSILXA 267 IN LTYFF+TWFPVYLV+ RG+SIL A Sbjct: 267 INALTYFFITWFPVYLVQARGMSILKA 293 >STM2962 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 452 Score = 365 bits (938), Expect = e-101, Method: Compositional matrix adjust. Identities = 170/268 (63%), Positives = 207/268 (77%), Gaps = 2/268 (0%) Query: 1 MLFLVTTVNYADRATLSIAGPALSKELHLDPVAMGYVFSAFGWSYAVAQVPCGWLLDRFG 60 MLF+VT+ NY DRATLSIAG ++K++ LDPV MGYVFSAF W+Y + Q+P GWLLDRFG Sbjct: 24 MLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFG 83 Query: 61 SKWVYALSIIVWSIFTAMQGLVGFLSAGAAVVLLFGLRFLVGIAEAPSFPANARIVASWF 120 SK VY SI +WS+FT +QG V S +V LF LRFLVG+AE+PSFP N+RIVA+WF Sbjct: 84 SKRVYFWSIFIWSVFTLLQGFVDIFSGFGIIVALFTLRFLVGLAESPSFPGNSRIVAAWF 143 Query: 121 PGNERGTASAFFNSGQYFATVIFAPLMGWIAHEYGWRHVFYVMGALGIVMGIAWIKTIYE 180 P ERGTA A FNS QYFATVIFAP+MGW+ HE GW HVF+ MG LGI++ W+K I+E Sbjct: 144 PAQERGTAVAIFNSAQYFATVIFAPIMGWLTHEVGWSHVFFFMGGLGIIISFIWLKVIHE 203 Query: 181 PKEHPAINEAEFDYIKQGGALVDMDATKDGKAH-DGGPRWDHIRQLLANRMMLGVYIGQY 239 P HP +N+ E +YI +GGAL++MD KD KA +W I+QLL +RMM+GVYIGQY Sbjct: 204 PNNHPGVNKKELEYIAEGGALINMD-QKDTKAKVPFSVKWGQIKQLLGSRMMIGVYIGQY 262 Query: 240 CINTLTYFFLTWFPVYLVKERGLSILXA 267 CIN LTYFF+TWFPVYLV+ RG+SIL A Sbjct: 263 CINALTYFFITWFPVYLVQARGMSILKA 290 >ygcZ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 450 Score = 365 bits (936), Expect = e-100, Method: Compositional matrix adjust. Identities = 167/267 (62%), Positives = 203/267 (76%) Query: 1 MLFLVTTVNYADRATLSIAGPALSKELHLDPVAMGYVFSAFGWSYAVAQVPCGWLLDRFG 60 MLF+VT+ NY DRATLSIAG ++K++ LDPV MGYVFSAF W+Y + Q+P GWLLDRFG Sbjct: 24 MLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFG 83 Query: 61 SKWVYALSIIVWSIFTAMQGLVGFLSAGAAVVLLFGLRFLVGIAEAPSFPANARIVASWF 120 SK VY SI +WS+FT +QG V S +V LF LRFLVG+AEAPSFP N+RIVA+WF Sbjct: 84 SKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWF 143 Query: 121 PGNERGTASAFFNSGQYFATVIFAPLMGWIAHEYGWRHVFYVMGALGIVMGIAWIKTIYE 180 P ERGTA + FNS QYFATVIFAP+MGW+ HE GW HVF+ MG LGIV+ W+K I+E Sbjct: 144 PAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHE 203 Query: 181 PKEHPAINEAEFDYIKQGGALVDMDATKDGKAHDGGPRWDHIRQLLANRMMLGVYIGQYC 240 P +HP +N+ E +YI GGAL++MD +W I+QLL +RMM+GVYIGQYC Sbjct: 204 PNQHPGVNKKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYC 263 Query: 241 INTLTYFFLTWFPVYLVKERGLSILXA 267 IN LTYFF+TWFPVYLV+ RG+SIL A Sbjct: 264 INALTYFFITWFPVYLVQARGMSILKA 290 >Z4105 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 450 Score = 363 bits (932), Expect = e-100, Method: Compositional matrix adjust. Identities = 166/267 (62%), Positives = 202/267 (75%) Query: 1 MLFLVTTVNYADRATLSIAGPALSKELHLDPVAMGYVFSAFGWSYAVAQVPCGWLLDRFG 60 MLF+VT+ NY DRATLSIAG ++K++ LDPV MGYVFSAF W+Y + Q+P GWLLDRFG Sbjct: 24 MLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFG 83 Query: 61 SKWVYALSIIVWSIFTAMQGLVGFLSAGAAVVLLFGLRFLVGIAEAPSFPANARIVASWF 120 SK VY SI +WS+FT +QG V S +V LF LRFLVG+AEAPSFP N+RIVA+WF Sbjct: 84 SKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWF 143 Query: 121 PGNERGTASAFFNSGQYFATVIFAPLMGWIAHEYGWRHVFYVMGALGIVMGIAWIKTIYE 180 P ERGTA + FNS QYFATVIFAP+MGW+ HE GW HVF+ MG LGI + W+K I+E Sbjct: 144 PAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWSHVFFFMGGLGIAISFIWLKVIHE 203 Query: 181 PKEHPAINEAEFDYIKQGGALVDMDATKDGKAHDGGPRWDHIRQLLANRMMLGVYIGQYC 240 P +HP +N+ E +YI GGAL++MD +W I+QLL +RMM+GVYIGQYC Sbjct: 204 PNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYC 263 Query: 241 INTLTYFFLTWFPVYLVKERGLSILXA 267 IN LTYFF+TWFPVYLV+ RG+SIL A Sbjct: 264 INALTYFFITWFPVYLVQARGMSILKA 290