BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0059.0166.p (247 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1362 [R] COG1011 Predicted hydrolase (HAD superfamily) Rso Ra... 157 2e-38 mll7634 [R] COG1011 Predicted hydrolase (HAD superfamily) Mlo Me... 152 6e-37 SMc00103 [R] COG1011 Predicted hydrolase (HAD superfamily) Sme S... 149 6e-36 BMEI1368 [R] COG1011 Predicted hydrolase (HAD superfamily) Bme B... 121 2e-27 SSO1159 [R] COG1011 Predicted hydrolase (HAD superfamily) Sso Su... 91 2e-18 >RSc1362 [R] COG1011 Predicted hydrolase (HAD superfamily) Rso Ralstonia solanacearum Length = 233 Score = 157 bits (397), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 85/209 (40%), Positives = 125/209 (59%), Gaps = 8/209 (3%) Query: 2 TIKAIVFDAYGTLYDVQSVADVTEDAFPGYGDIITQVWRIKQLEYSWLRSLM----RRYQ 57 +I+A+VFDAYGTL+DV SVA E FPG G+ ++ +WR +Q++Y+ +RSL Y+ Sbjct: 3 SIRAVVFDAYGTLFDVYSVAARAEQLFPGKGEALSVLWRDRQIDYTRIRSLAGPSGEHYK 62 Query: 58 DFAVATRDSLAYTLRCLGLQYDAATFARIIDKYQHLALYPDAVAALEAMKDKKL--AILS 115 F T D+L Y L L A ++ +Y L+ +P+ V L +++ L ILS Sbjct: 63 PFWDVTVDALRYACARLNLPLGNHAEATLMREYACLSAFPENVPVLRQLREMGLPLGILS 122 Query: 116 NGSPDMLNALVRNSGLDRVLDATISVDAHKVFKPAPEAYTLIEEVLKVPPAEVLFISSNP 175 NG+P ML V+++G+ + D +SVDA +++K AP AY L VP A++LF+SSN Sbjct: 123 NGNPQMLEIAVKSAGMSGLFDHVLSVDAVRLYKTAPAAYALAPRAFGVPAAQILFVSSNG 182 Query: 176 WDACGAKSFGLNVAWIERVT--PEAMALA 202 WDACGA G WI R+ PEA+ +A Sbjct: 183 WDACGATWHGFTTFWINRLGHPPEALDVA 211 >mll7634 [R] COG1011 Predicted hydrolase (HAD superfamily) Mlo Mesorhizobium loti Length = 219 Score = 152 bits (385), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 88/220 (40%), Positives = 120/220 (54%), Gaps = 11/220 (5%) Query: 1 MTIKAIVFDAYGTLYDVQSVADVTEDAFPGYGDIITQVWRIKQLEYSWLRSLMRRYQDFA 60 M A VFDAYGTL+DV + D G +++++WR KQLEYSW+RSLM Y DF Sbjct: 1 MQYAAYVFDAYGTLFDVHAAVRRHADRIGPDGQLLSEIWRAKQLEYSWVRSLMGSYADFW 60 Query: 61 VATRDSLAYTLRCLGLQYDAATFARIIDKYQHLALYPDAVAALEAMK--DKKLAILSNGS 118 T +L + LR + D ++++ Y L YP+ A L+A+K +LA+LSNGS Sbjct: 61 QLTEQALDFALRKVP-SADPGLRTKLLEAYWRLDCYPEVPAVLKALKASGARLALLSNGS 119 Query: 119 PDMLNALVRNSGLDRVLDATISVDAHKVFKPAPEAYTLIEEVLKVPPAEVLFISSNPWDA 178 P+ML A V+++ LD+VLD SVD + FK P Y ++ ++ P V F SSN WD Sbjct: 120 PEMLEAAVKSAALDQVLDDIYSVDTVRRFKTDPAVYDMVATGWRLYPGAVSFQSSNRWDI 179 Query: 179 CGAKSFGLNVAWIERVT--------PEAMALACVESETVA 210 GA FG WI R P A+ L +ES A Sbjct: 180 AGATKFGFRTVWINRSNQPEEYRDFPPALILPTLESLVTA 219 >SMc00103 [R] COG1011 Predicted hydrolase (HAD superfamily) Sme Sinorhizobium meliloti Length = 220 Score = 149 bits (376), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 84/195 (43%), Positives = 109/195 (55%), Gaps = 3/195 (1%) Query: 1 MTIKAIVFDAYGTLYDVQSVADVTEDAFPGYGDIITQVWRIKQLEYSWLRSLMRRYQDFA 60 M+ A VFDAYGTL+DV + +A G +++WR KQLEYSW+RSLM Y DF Sbjct: 1 MSYAAYVFDAYGTLFDVHAAVRRHAEAIGPDGQAFSELWRAKQLEYSWVRSLMGAYVDFW 60 Query: 61 VATRDSLAYTLRCLGLQYDAATFARIIDKYQHLALYPDAVAALEAMKD--KKLAILSNGS 118 T SL Y + D ++D Y L YP+ A L+ +K+ ++AILSNGS Sbjct: 61 ELTEQSLDYAFQRFP-SADPKLKKPLLDAYWALDCYPEVPAVLKGLKELGARIAILSNGS 119 Query: 119 PDMLNALVRNSGLDRVLDATISVDAHKVFKPAPEAYTLIEEVLKVPPAEVLFISSNPWDA 178 P ML + V+N+ LD ++D SVDA K FK AP Y L+ ++ P V F SSN WD Sbjct: 120 PAMLASAVKNAALDIIIDDVFSVDAVKAFKTAPAVYDLVTTSYRLYPQAVSFQSSNRWDI 179 Query: 179 CGAKSFGLNVAWIER 193 GA FG WI R Sbjct: 180 AGATKFGFRTVWINR 194 >BMEI1368 [R] COG1011 Predicted hydrolase (HAD superfamily) Bme Brucella melitensis Length = 252 Score = 121 bits (303), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 77/182 (42%), Positives = 103/182 (56%), Gaps = 5/182 (2%) Query: 1 MTIKAIVFDAYGTLYDVQSVADVTEDAFPGYGDIITQVWRIKQLEYSWLRSLMRRYQDFA 60 M+ + FDAYGTL+DV S D G ++++WR KQLEYSW+ SLM Y DF Sbjct: 1 MSYSSYAFDAYGTLFDVHSAVRRHADKAGPDGRALSELWRAKQLEYSWVLSLMGAYSDFW 60 Query: 61 VATRDSLAYTLRCLGLQYDAATFARIIDKYQHLALYPDAVAALEAMKDK--KLAILSNGS 118 T +SL Y L D A ++D Y L YP+ AAL+A+KD+ +LAILSNGS Sbjct: 61 KLTEESLDYALAHYP-SVDPALRNDLLDAYWKLDCYPEVPAALKALKDRGARLAILSNGS 119 Query: 119 PDMLNALVRNSGLDRVLDATISVDAHKVFKPAPEAYTLIEEVLK--VPPAEVLFISSNPW 176 P ML A VR++ LD +LD ISVD K +K + Y LI + +PP+ ++ W Sbjct: 120 PAMLEAAVRSAALDVLLDDVISVDMVKKYKTSLAVYELIAVQWRSTLPPSRSSHQTAGMW 179 Query: 177 DA 178 A Sbjct: 180 RA 181 >SSO1159 [R] COG1011 Predicted hydrolase (HAD superfamily) Sso Sulfolobus solfataricus Length = 198 Score = 91.3 bits (225), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 57/190 (30%), Positives = 96/190 (50%), Gaps = 25/190 (13%) Query: 4 KAIVFDAYGTLYDVQSVADVTEDAFPGYGDIITQVWRIKQLEYSWLRSLMRRYQDFAVAT 63 K + FD YGT+ D+ + I+Q R KQLEY+WL ++M RY DF T Sbjct: 6 KILAFDLYGTILDLSA---------------ISQEMRRKQLEYTWLLTIMGRYVDFDEIT 50 Query: 64 RDSLAYTLRCLGLQYDAATFARIIDKYQHLALYPDAVAALEAMKDKKLAILSNGSPDMLN 123 + +++YTL ++ + ++K++ L + DA+ + + ILSNG+ + Sbjct: 51 KIAISYTLGEDKIEEE-------LNKWRSLRTHQDAIYLKDISTIADIYILSNGTTKTIE 103 Query: 124 ALVRNSGLDRVLDATISVDAHKVFKPAPEAYTLIEEVLKVPPAEVLFISSNPWDACGAKS 183 L++ +GL S + K +KP+P+ Y E +K E +SSNP+D GAK+ Sbjct: 104 ELLKLNGLSSYFKGIFSAERVKEYKPSPKVYRYFLEAVK---GEAYLVSSNPFDVIGAKN 160 Query: 184 FGLNVAWIER 193 G+ ++ R Sbjct: 161 SGMKGIYVNR 170