BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0059.0135.p         (457 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

MJ0928 [J] COG2890 Methylase of polypeptide chain release factor...    76   1e-13
PH1731 [J] COG2890 Methylase of polypeptide chain release factor...    70   1e-11
PAB0284 [J] COG2890 Methylase of polypeptide chain release facto...    65   2e-10
PA2179 [J] COG2890 Methylase of polypeptide chain release factor...    64   7e-10

>MJ0928 [J] COG2890 Methylase of polypeptide chain release factors Mja
           Methanococcus jannaschii
          Length = 197

 Score = 76.3 bits (186), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 6/123 (4%)

Query: 232 IPRRRAIDLGTGSGVHAILASDHSAT-VVGADVSPRAIAFSNFNGALNEKSNIDFVTSDL 290
           +  +  +++G G+G+ +I  +   A  +VG D++P A+  +  N  LN   NI F  SDL
Sbjct: 33  VKNKDVLEIGVGTGLISIACAKKGAKKIVGVDINPYAVKLAKENAKLNN-VNISFFESDL 91

Query: 291 FDSIDGTCDLLVCNPPYAPDTAAKASDNF----WSGGIEGTELLRRVVEALPTRLDADGT 346
           F+++ G  D+++ NPPY P +  +  D++    + GG +G E+L R +  LP  L   G 
Sbjct: 92  FENVTGKFDVILFNPPYLPTSEDEKIDSYLNFAFDGGKDGREILDRFIYELPNYLKKGGV 151

Query: 347 AYI 349
             I
Sbjct: 152 VQI 154


>PH1731 [J] COG2890 Methylase of polypeptide chain release factors Pho
           Pyrococcus horikoshii
          Length = 198

 Score = 69.7 bits (169), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 42/110 (38%), Positives = 65/110 (59%), Gaps = 1/110 (0%)

Query: 237 AIDLGTGSGVHAILASDHSATVVGADVSPRAIAFSNFNGALNEKSNIDFVTSDLFDSIDG 296
            +D+GTG+G+ A+LA+  +  VVG D++ +AI  +  N  +N   N+ F+ SDLF++I G
Sbjct: 40  VLDVGTGTGILALLAARRARFVVGLDINEKAINLAWKNAKINGIKNVVFILSDLFENIRG 99

Query: 297 TCDLLVCNPPYAPDTAAK-ASDNFWSGGIEGTELLRRVVEALPTRLDADG 345
           T DL+V NPPY P    K   D    GG  G E++ R + ++   L + G
Sbjct: 100 TFDLIVFNPPYLPGEEIKDKVDLALIGGKTGGEVISRFLGSVKDYLSSRG 149


>PAB0284 [J] COG2890 Methylase of polypeptide chain release factors Pab
           Pyrococcus abyssi
          Length = 197

 Score = 65.5 bits (158), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 44/131 (33%), Positives = 71/131 (54%), Gaps = 3/131 (2%)

Query: 237 AIDLGTGSGVHAILASDHSATVVGADVSPRAIAFSNFNGALNEKSNIDFVTSDLFDSIDG 296
            +D+GTGSG+ A+LA+  +  VVG D++ +AI  +  N  LN   N+ FV SDLF ++ G
Sbjct: 40  VLDVGTGSGILALLAAKKAKFVVGLDINEKAIDLAWRNAQLNGIKNVVFVVSDLFRNLRG 99

Query: 297 TCDLLVCNPPYAP-DTAAKASDNFWSGGIEGTELLRRVVEALPTRLDADGTAYINALFPN 355
              L++ NPPY P D      D    GG  G+E++ + +  +   L   G   I  ++ +
Sbjct: 100 KFTLILFNPPYLPGDDVKDEIDLALIGGKTGSEVILKFLSDVEDYLLPGGRILI--VYSS 157

Query: 356 PPGTKIRDHFD 366
             G  +R+ F+
Sbjct: 158 LTGLNVREAFE 168


>PA2179 [J] COG2890 Methylase of polypeptide chain release factors Pae
           Pseudomonas aeruginosa
          Length = 316

 Score = 63.9 bits (154), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 61/187 (32%), Positives = 88/187 (47%), Gaps = 14/187 (7%)

Query: 235 RRAIDLGTGSGVHAILASDH--SATVVGADVSPRAIAFSNFNGALNEKSNIDFVTSDLFD 292
           RRA D+G G+G  AI  +     A V G D++P A+  +  N AL    N+    SDL  
Sbjct: 138 RRAADIGCGAGPGAIRIAMACPDAEVHGLDINPAALDLARVNAALAGVGNLTLARSDLLS 197

Query: 293 SIDGTCDLLVCNPPYAPDTAAKASDNFWSGGIEGTELLRRVVEALPTRLDADGTAYINAL 352
              G  DL+V NPPY  D + +A  +   GG+ G  L   +V+A   RL+A G+     L
Sbjct: 198 QAPGRFDLIVANPPYLLDASERAYRH--GGGMLGAGLSLAIVDAALERLEAGGSLL---L 252

Query: 353 FPNPPGTKIRDHFDAWLEGNLT--EWDVLDHTWPVPGYQDLFSEQ-PFQGDMSAWRFGVV 409
           +      +  D F A +   L   EWD  D+    P   D+F+E+        A R  VV
Sbjct: 253 YTGVAMVEGGDPFLARIRERLASREWD-WDYQELDP---DVFAEELDSPAYREAERIAVV 308

Query: 410 SMRRSRT 416
            +R +R+
Sbjct: 309 GLRVTRS 315