BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0059.0116.p (291 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr0868 [GER] COG0697 Permeases of the drug/metabolite transport... 317 2e-86 SMb20112 [GER] COG0697 Permeases of the drug/metabolite transpor... 114 2e-25 RP076 [GER] COG0697 Permeases of the drug/metabolite transporter... 103 3e-22 RC0106 [GER] COG0697 Permeases of the drug/metabolite transporte... 101 2e-21 CC0093 [GER] COG0697 Permeases of the drug/metabolite transporte... 101 2e-21 >mlr0868 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 293 Score = 317 bits (812), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 154/289 (53%), Positives = 211/289 (73%) Query: 1 MDRTPSKTRAALWMSGWLALMLIVAVAGREATREVNVFQLMAVRGALGFAMLYPLIHING 60 M TPS +AA WM+ ++ L ++VAGR T E+NVFQ++ +R +GF +L PL+ +G Sbjct: 1 MAPTPSIPKAAFWMALSISSFLAMSVAGRATTAELNVFQVLELRSVIGFFILLPLVLTSG 60 Query: 61 GFAIVKTARVHVHIARNLIHFCAQLGWFFALTLIPIGQVVAIEFTMPIWTAILAASFLGE 120 GFA ++T R HIARN++H+ Q W +ALTLIP+ +++IEFT PIWTAILA +FLGE Sbjct: 61 GFAAMRTQRPLAHIARNVVHYSGQAAWLYALTLIPLAVLISIEFTTPIWTAILAVTFLGE 120 Query: 121 RMTAWKIVAIVLGLVGVFVIVRPAAGAINPGQLIALAAAVGFGISVAVVKSLTRTEQTLT 180 R++ K+ A+ LGL+GV VIVRP A++PG L+ L AAV FGIS+ +VKSLTRT+ + Sbjct: 121 RLSRPKLAAVGLGLIGVVVIVRPGVDAVDPGHLVVLGAAVCFGISLVLVKSLTRTDSVVR 180 Query: 181 IMFWMLVVQSLASIGPALYVWTWPPLSTWGWLAVIAFCGTFSHYCMARALLHADATVVIP 240 I+FWML++QS + PALYVW P L W W+ +IAF G SH+CMARAL +ADATV+ P Sbjct: 181 IIFWMLIIQSALGLVPALYVWRTPSLELWPWILLIAFTGMSSHFCMARALTYADATVISP 240 Query: 241 MDFVRVPLTAIAGWLIYAERLDVYTVLGAAMILAGNLMNLKPTARKPAR 289 MDF+RVPL+A+ GWL+Y E++D +T GA +IL GNL+NL+ +PA Sbjct: 241 MDFLRVPLSALVGWLLYHEQIDAFTAGGALLILMGNLLNLQRKPVQPAE 289 >SMb20112 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 295 Score = 114 bits (286), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 69/203 (33%), Positives = 111/203 (54%) Query: 71 HVHIARNLIHFCAQLGWFFALTLIPIGQVVAIEFTMPIWTAILAASFLGERMTAWKIVAI 130 VH R +I A + F A+T IP+ AI FTMP++ A+ + FLGER +A ++ + Sbjct: 78 SVHAIRAVIKLLALVAAFIAVTEIPLASATAIAFTMPLFVALGSVLFLGERFSAARVFGL 137 Query: 131 VLGLVGVFVIVRPAAGAINPGQLIALAAAVGFGISVAVVKSLTRTEQTLTIMFWMLVVQS 190 V G G+ ++VRP A G ALA+AVG I ++K E L+I + L+V Sbjct: 138 VAGFAGILIVVRPGAATFQSGAAWALASAVGLAIVALLMKVSAEREDPLSIAWLNLLVTV 197 Query: 191 LASIGPALYVWTWPPLSTWGWLAVIAFCGTFSHYCMARALLHADATVVIPMDFVRVPLTA 250 + AL W P L + + + G F+ ARA+ ADA++++ +DF+R+P+ Sbjct: 198 PVAFVMALPFWQTPSLFSLALMTLQGIGGLFAQLSFARAMKLADASLLVIVDFIRLPIAL 257 Query: 251 IAGWLIYAERLDVYTVLGAAMIL 273 I G +++ E + + V+G A+IL Sbjct: 258 ILGLVLFGEPIRLEVVIGGAIIL 280 >RP076 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rpr Rickettsia prowazekii Length = 294 Score = 103 bits (258), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 66/227 (29%), Positives = 114/227 (50%), Gaps = 1/227 (0%) Query: 51 MLYPLIHINGGFAIVKTARVHVHIARNLIHFCAQLGWFFALTLIPIGQVVAIEFTMPIWT 110 +L P + G A+ KT+R VH+ R L+ F W + LT+ P+ + F +P++T Sbjct: 52 VLLPFVVYYGKNAL-KTSRPFVHVLRGLLLFFGMTSWTYGLTIAPVTTATVVSFAIPLFT 110 Query: 111 AILAASFLGERMTAWKIVAIVLGLVGVFVIVRPAAGAINPGQLIALAAAVGFGISVAVVK 170 ILA L E + + V V+G +G+ V+++P NP L + AA+ F + + K Sbjct: 111 LILAVFILNENIIWQRWVVTVVGFIGLVVMLKPHTKDFNPEILYLILAAISFAMLDIINK 170 Query: 171 SLTRTEQTLTIMFWMLVVQSLASIGPALYVWTWPPLSTWGWLAVIAFCGTFSHYCMARAL 230 E L+++F+ +V ++ S+ A+ W P L V+ G+F + + +A Sbjct: 171 KFVVKESMLSMLFYSAIVTAMVSLPVAMQYWITPSSFELALLFVLGSSGSFILFFLLKAF 230 Query: 231 LHADATVVIPMDFVRVPLTAIAGWLIYAERLDVYTVLGAAMILAGNL 277 DAT P ++ + ++AIA + I+ E D TV GA +I+ L Sbjct: 231 SIVDATATAPYRYLELVISAIAAYFIFNEFPDKSTVHGAVIIIPATL 277 >RC0106 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rco Rickettsia conorii Length = 294 Score = 101 bits (251), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 72/280 (25%), Positives = 131/280 (46%), Gaps = 5/280 (1%) Query: 16 GWLALMLIVAVAGREATR----EVNVFQLMAVRGALGFAMLYPLIHINGGFAIVKTARVH 71 GW L L+ + A ++ ++ F++ R +L P + + G +KT+R Sbjct: 13 GWFLLSLVSSSANDVISKYLGTRLHSFEVAFFRFFFSSIVLLPFV-VYYGKNTLKTSRPF 71 Query: 72 VHIARNLIHFCAQLGWFFALTLIPIGQVVAIEFTMPIWTAILAASFLGERMTAWKIVAIV 131 VHI R L+ F W + LT+ P+ + F++P++T ILA FL E + + V V Sbjct: 72 VHILRGLLLFFGMTSWTYGLTIAPVTTATVVSFSIPLFTLILAVFFLNENIIWPRWVVTV 131 Query: 132 LGLVGVFVIVRPAAGAINPGQLIALAAAVGFGISVAVVKSLTRTEQTLTIMFWMLVVQSL 191 +G +G+ V ++P A NP L + AA+ F + + K E ++++F+ +V ++ Sbjct: 132 VGFIGLVVTLKPHAEDFNPEILYFVLAAISFAMLDIINKKFVIKESMISMLFYSAIVTAI 191 Query: 192 ASIGPALYVWTWPPLSTWGWLAVIAFCGTFSHYCMARALLHADATVVIPMDFVRVPLTAI 251 S+ A W P L V+ G+ + + +A DAT P ++ + ++ I Sbjct: 192 VSLPVASQYWLTPSSFELALLFVLGSSGSLILFFLLKAFSMVDATATAPYRYLELVISVI 251 Query: 252 AGWLIYAERLDVYTVLGAAMILAGNLMNLKPTARKPARAR 291 A + I+ E D T+ GA +I+ L + + R Sbjct: 252 AAYFIFNEFPDKSTLHGAVIIIPTTLFIIYSEKKAMNRKH 291 >CC0093 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ccr Caulobacter vibrioides Length = 297 Score = 101 bits (251), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 79/279 (28%), Positives = 133/279 (47%), Gaps = 17/279 (6%) Query: 9 RAALWM----SGWLALMLIVAVAGREATREVNVFQLMAVRGALGFAMLYPLIHIN--GGF 62 R ALWM G+ + ++ G + + F R G +L PLI + G F Sbjct: 8 RGALWMLASAVGFTVMTTLIKFLGDDYPAALQTFY----RQLAGVLVLLPLIARDWRGAF 63 Query: 63 AIVKTARVHVHIARNLIHFCAQLGWFFALTLIPIGQVVAIEFTMPIWTAILAASFLGERM 122 +T R + I R+ A + F+A +P+ A+ FT +W LA L E + Sbjct: 64 ---RTTRPGIVIFRSSAGVLALIMSFYAYQKLPLADANALSFTRTLWLVPLAGLVLREPI 120 Query: 123 TAWKIVAIVLGLVGVFVIVRPAAGAINP----GQLIALAAAVGFGISVAVVKSLTRTEQT 178 +I A ++G VGV ++++P AG + QL AL AA F +++ +K +TR Sbjct: 121 GPRRISAALVGFVGVLIMLQPGAGGVEAWLGWPQLCALGAAFLFALTITGMKVMTRDHTP 180 Query: 179 LTIMFWMLVVQSLASIGPALYVWTWPPLSTWGWLAVIAFCGTFSHYCMARALLHADATVV 238 ++ + V+ + +I PAL+VW WP G LA + GT + + + +A V+ Sbjct: 181 FVLLVYAAVLGLVFAIPPALFVWRWPTWPDLGLLAAMGVIGTLTQGAYIKGMEAGEAAVM 240 Query: 239 IPMDFVRVPLTAIAGWLIYAERLDVYTVLGAAMILAGNL 277 P+D+ R+ I G+L++ E TV+GA +++ L Sbjct: 241 APVDYTRLVFAVIVGFLLFQEVPRTATVVGAVIVVGSTL 279