BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0059.0062.p (242 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0492 [R] COG1540 Uncharacterized proteins, homologs of lactam ... 202 4e-52 PAB2445 [R] COG1540 Uncharacterized proteins, homologs of lactam... 187 3e-47 PH0986 [R] COG1540 Uncharacterized proteins, homologs of lactam ... 186 3e-47 Cj1541 [R] COG1540 Uncharacterized proteins, homologs of lactam ... 185 8e-47 VCA0776 [R] COG1540 Uncharacterized proteins, homologs of lactam... 184 2e-46 >PA0492 [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B Pae Pseudomonas aeruginosa Length = 252 Score = 202 bits (515), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 104/235 (44%), Positives = 141/235 (60%), Gaps = 4/235 (1%) Query: 2 VVINCDMGEAYGLYKMGD--DKALMPHIDVANVACGFHASDFNHMRKTVQLAKQFGVKVG 59 V +N DMGE +G + +GD D A+MP I AN+A GFHA D + MR+TV++A + GV +G Sbjct: 4 VDLNSDMGEGFGPWTIGDGVDAAIMPLISSANIATGFHAGDPSSMRRTVEMAAEHGVAIG 63 Query: 60 AHPSLPDLQGFGRREMKIDREELANCLLYQIGALKAFLDAEGMALNHIKPHGALYGMASR 119 AHP DL GFGRR + EL N +LYQ+GAL+ F +G++L H+KPHGALY +R Sbjct: 64 AHPGFRDLVGFGRRHIAAPAIELVNDMLYQLGALREFARLQGLSLQHVKPHGALYMHLAR 123 Query: 120 SEEIAEAVADAADVYKVPLL--GMKGTLHQKVYERRGHAFVAEYYADLDYNADGSLIITR 177 E A + + LL M G+ ++ G V E+YAD DY+ GS++ TR Sbjct: 124 DEVAARLFVETLQRLEPELLLYCMPGSATWRIGRELGQPLVREFYADRDYDRSGSIVFTR 183 Query: 178 EHEAKDPADAATRCARAVNEGKTRTVAGNDIVVGSDSICIHSDTPNAVAIAEAVR 232 A DP A + RA EGK RTV G D+ + DS+CIHSDTP A+ + + R Sbjct: 184 RVAALDPQQVADKVLRACREGKVRTVEGEDLDIAFDSVCIHSDTPGALELVASTR 238 >PAB2445 [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B Pab Pyrococcus abyssi Length = 255 Score = 187 bits (474), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 99/234 (42%), Positives = 142/234 (60%), Gaps = 4/234 (1%) Query: 4 INCDMGEAYGLYKMGDDKALMPHIDVANVACGFHASDFNHMRKTVQLAKQFGVKVGAHPS 63 +N D+GE++G YK+G D+ +M +I AN+ACG+HA D MR+TV+LAK+ V+VGAHP Sbjct: 5 LNSDLGESFGRYKLGLDEEVMRYITSANIACGWHAGDPIVMRRTVKLAKENNVQVGAHPG 64 Query: 64 LPDLQGFGRREMKIDREELANCLLYQIGALKAFLDAEGMALNHIKPHGALYGMASRSEEI 123 PDL GFGRR MK+ EE N +LYQIGAL AF AEG+ L H+KPHGALY + EE+ Sbjct: 65 YPDLMGFGRRYMKLTPEEARNYILYQIGALYAFAKAEGVELQHVKPHGALYNAMVKEEEL 124 Query: 124 AEAVADAADVY--KVPLLGMKGTLHQKVYERRGHAFVAEYYADLDYNADGSLIITREHEA 181 A AV + + + L+ + + ++ E G E +AD YN DG+L+ + A Sbjct: 125 ARAVIEGILDFDKNLILVTLSNSRVAEIAEEMGLKVAHEVFADRAYNPDGTLVPRGKPGA 184 Query: 182 --KDPADAATRCARAVNEGKTRTVAGNDIVVGSDSICIHSDTPNAVAIAEAVRE 233 +D + A R V +G R + G + + D+IC+H D P A+ I +R+ Sbjct: 185 VIEDKEEIAERVISMVKDGGVRAINGEWVELRVDTICVHGDNPKALEITSHIRK 238 >PH0986 [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B Pho Pyrococcus horikoshii Length = 255 Score = 186 bits (473), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 103/238 (43%), Positives = 143/238 (60%), Gaps = 4/238 (1%) Query: 2 VVINCDMGEAYGLYKMGDDKALMPHIDVANVACGFHASDFNHMRKTVQLAKQFGVKVGAH 61 V +N D+GE++G YK+G D+ +M +I ANVACG+HA D MRKTV+LAK+ V+VGAH Sbjct: 3 VDLNSDLGESFGRYKLGLDEEVMKYITSANVACGWHAGDPLVMRKTVRLAKENDVQVGAH 62 Query: 62 PSLPDLQGFGRREMKIDREELANCLLYQIGALKAFLDAEGMALNHIKPHGALYGMASRSE 121 P PDL GFGRR MK+ EE N +LYQ+GAL AF AEG+ L H+KPHGALY + E Sbjct: 63 PGYPDLMGFGRRYMKLTPEEARNYILYQVGALYAFAKAEGLELQHVKPHGALYNAMVKEE 122 Query: 122 EIAEAVADAA-DVYK-VPLLGMKGTLHQKVYERRGHAFVAEYYADLDYNADGSLIITREH 179 ++A AV + D K + L+ + + + E G E +AD YN DG+L+ Sbjct: 123 DLARAVIEGILDFDKDLILVTLSNSRVADIAEEMGLKVAHEVFADRAYNPDGTLVPRGRP 182 Query: 180 EA--KDPADAATRCARAVNEGKTRTVAGNDIVVGSDSICIHSDTPNAVAIAEAVREAV 235 A +D + A R V +G R + G + + D+IC+H D P AV I +R+ + Sbjct: 183 GAVIEDKEEIAERVISMVKDGGIRAINGEWVDLKVDTICVHGDNPKAVEITSYIRKVL 240 >Cj1541 [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B Cje Campylobacter jejuni Length = 255 Score = 185 bits (469), Expect = 8e-47, Method: Compositional matrix adjust. Identities = 97/241 (40%), Positives = 144/241 (59%), Gaps = 6/241 (2%) Query: 2 VVINCDMGEAYGLYKMGDDKALMPHIDVANVACGFHASDFNHMRKTVQLAKQFGVKVGAH 61 V +N D+GE++G YKMG D+ ++ + NVACGFHA D M +T+ LAKQ GV +GAH Sbjct: 4 VDLNSDLGESFGAYKMGMDEEILKFVSSVNVACGFHAGDPCVMDETLNLAKQNGVCIGAH 63 Query: 62 PSLPDLQGFGRREMKIDREELANCLLYQIGALKAFLDAEGMALNHIKPHGALYGMASRSE 121 PS PDL GFGRR M+I EE N LYQ+GAL F A+GM + H K HGALY MA+ E Sbjct: 64 PSYPDLLGFGRRNMQISFEEAKNYALYQLGALFGFAKAKGMKIQHFKAHGALYNMAAIDE 123 Query: 122 EIAEAVADAADVY--KVPLLGMKGTLHQKVYERRGHAFVAEYYADLDYNADGSLIITREH 179 +A A+ +A + + LG+ + + +++G + E +AD YN DG+L ++R+ Sbjct: 124 NLALALCEAVASFDENIIFLGLSNSAMNEAAKKKGLRYANEVFADRAYNDDGTL-VSRKL 182 Query: 180 EAK---DPADAATRCARAVNEGKTRTVAGNDIVVGSDSICIHSDTPNAVAIAEAVREAVR 236 E D A R + + E K ++ G +I + +DSIC+H D A+ + ++E ++ Sbjct: 183 EGALIHDENLAIKRVIKMIKESKVTSINGKEIDLKADSICVHGDNAKALEFVKKIKENLK 242 Query: 237 P 237 Sbjct: 243 K 243 >VCA0776 [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B Vch Vibrio cholerae Length = 246 Score = 184 bits (467), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 92/239 (38%), Positives = 146/239 (61%), Gaps = 5/239 (2%) Query: 2 VVINCDMGEAYGLYKMGDDKALMPHIDVANVACGFHASDFNHMRKTVQLAKQFGVKVGAH 61 + +NCDMGE++G++ MG D+ +MP ID+AN+ACGFHASD + M +T+ LA + V +GAH Sbjct: 6 IQLNCDMGESFGVWTMGADEEVMPWIDMANIACGFHASDPHVMSRTIDLALEHEVMIGAH 65 Query: 62 PSLPDLQGFGRREMKIDREELANCLLYQIGALKAFLDAEGMALNHIKPHGALYGMASRSE 121 PS PDLQGFGRR + ++ +E++ +LYQ+GALKA +++ L+++KPHGALY Sbjct: 66 PSYPDLQGFGRRSLAMNEQEVSEIILYQVGALKALCESKNGQLSYVKPHGALYNDMMSDP 125 Query: 122 EIAEAVADAADVYKVPLLGMKGTLHQ---KVYERRGHAFVAEYYADLDYNADGSLIITRE 178 I AV DA + +PL+ + +Q + +R + E +AD Y A+G L + Sbjct: 126 SIFRAVVDAVSCFNLPLMVLASANNQDYLDIADRFDVPLLFEAFADRTYLANGKLTPRSQ 185 Query: 179 HEAKDPADAA--TRCARAVNEGKTRTVAGNDIVVGSDSICIHSDTPNAVAIAEAVREAV 235 A ++ A + + GK + G I + +D++C+H D PNAV++ +R A+ Sbjct: 186 PNAVLSSEEAILNQVRQIARYGKVTSSDGFVIPIEADTLCVHGDNPNAVSLIARIRAAL 244