BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0059.0059.p (466 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0494 [I] COG0439 Biotin carboxylase Pae Pseudomonas aeruginosa 527 e-149 BMEI1063 [I] COG0439 Biotin carboxylase Bme Brucella melitensis 493 e-139 alr0939 [I] COG0439 Biotin carboxylase Nos Nostoc sp. PCC 7120 488 e-137 SMc01345 [I] COG0439 Biotin carboxylase Sme Sinorhizobium meliloti 486 e-137 AGc2451 [I] COG0439 Biotin carboxylase Atu Agrobacterium tumefac... 481 e-135 >PA0494 [I] COG0439 Biotin carboxylase Pae Pseudomonas aeruginosa Length = 458 Score = 527 bits (1358), Expect = e-149, Method: Compositional matrix adjust. Identities = 279/450 (62%), Positives = 340/450 (75%) Query: 3 IKKLLIANRGEIAVRIIRAARDLGIATVQVYSKADQDSLAVRLADEAVDIGPPQASKSYL 62 + KLL+ANRGEIAVRIIRAA+ LGI TV V S+AD+DSLA RLADE IGP +A +SYL Sbjct: 5 LNKLLVANRGEIAVRIIRAAQALGIPTVAVCSEADRDSLAARLADEVRLIGPARADRSYL 64 Query: 63 NQAAILAAARSTGADAIHPGYGFLAENAEFAAAVEAAGLIFVGPTARSIRLMGDKVAARE 122 + AIL AAR TGAD+IHPGYGFL+EN FA AV+AAGL+FVGP A++IR MGDK AR Sbjct: 65 DIEAILMAARETGADSIHPGYGFLSENPAFAEAVQAAGLVFVGPEAQTIRRMGDKAEARR 124 Query: 123 AAAAAGVPTVPGSQGRLESAEAAFALVEKTGFPVMIKAAAGGGGRGIRIARSPEEFQHLM 182 A AAGVP VPGS G L +AA A E+ G+P+++KA+AGGGGRGIRIA +E + Sbjct: 125 TAMAAGVPVVPGSPGELGDLDAALACAEEVGYPLLVKASAGGGGRGIRIAHDADELRREF 184 Query: 183 PQAQAEALAAFGDGGLYVEKLIEGARHIEVQVLGDGRDVIHCFERECSLQRRRQKVWEEA 242 P AQ EA AAFG +Y+E+ I ARHIEVQ+LGDG +H FERECSLQRRRQKV+EEA Sbjct: 185 PIAQREAQAAFGSPAVYLERFIRQARHIEVQILGDGERAVHLFERECSLQRRRQKVFEEA 244 Query: 243 PSPSLTQAVRERLCSSAVALARAVNYRGAGTLEYLYDDATGEFYFLEMNTRIQVEHPVTE 302 PS +L A R+ LC SAV LA+++ YRGAGTLEYL+D +GEF+F+EMNTRIQVEHPV+E Sbjct: 245 PSAALDGAQRQALCESAVRLAQSLGYRGAGTLEYLFDAHSGEFFFIEMNTRIQVEHPVSE 304 Query: 303 MITGIDLVREMIQIAGGERLRISQNEMRVSGHSIEVRINAEDPARNFLPNPGTVSALSLP 362 M+TGIDLV+ M++IA GE L Q ++R++G ++E+RINAEDPARNF P+PGTV L P Sbjct: 305 MVTGIDLVQAMLRIAAGEALPWRQEDIRLNGAALEMRINAEDPARNFFPSPGTVERLEWP 364 Query: 363 VGDGVRFDSMLYQGYTVPPFYDSLLGKLIVHDKDRPSAMKKLERALAELTVGGIFTTKPL 422 G+GVR DS LY GY VPP+YDSLL KLIVH +DR A + +AL + G+ TT PL Sbjct: 365 QGEGVRVDSHLYPGYRVPPYYDSLLAKLIVHGRDRDEAFARARQALERTVLAGMATTLPL 424 Query: 423 HQALARDADVKAGRFHTAWLEPWLESHAAA 452 H+ L DA V+A +F TA LE WL AA Sbjct: 425 HRWLLADARVQAAQFDTATLETWLAERTAA 454 >BMEI1063 [I] COG0439 Biotin carboxylase Bme Brucella melitensis Length = 459 Score = 493 bits (1269), Expect = e-139, Method: Compositional matrix adjust. Identities = 246/448 (54%), Positives = 319/448 (71%), Gaps = 10/448 (2%) Query: 3 IKKLLIANRGEIAVRIIRAARDLGIATVQVYSKADQDSLAVRLADEAVDIGPPQASKSYL 62 +K+LIANRGEIA+R++RA ++LGI TV V+S AD D++ VRLADE+V IGPP + SYL Sbjct: 9 FQKILIANRGEIALRVLRACKELGIKTVAVHSTADADAMHVRLADESVCIGPPPSRDSYL 68 Query: 63 NQAAILAAARSTGADAIHPGYGFLAENAEFAAAVEAAGLIFVGPTARSIRLMGDKVAARE 122 N I+AA TGADAIHPGYGFL+ENA+FA +EA + F+GPTA IR+MGDK+ A+ Sbjct: 69 NIHQIVAACEITGADAIHPGYGFLSENAKFAEILEAHDITFIGPTASHIRIMGDKIEAKR 128 Query: 123 AAAAAGVPTVPGSQGRLESAEAAFALVEKTGFPVMIKAAAGGGGRGIRIARSPEEFQHLM 182 A G+P VPGS G + A + ++ G+PV+IKA+AGGGGRG+++ARS EE + Sbjct: 129 TAKRLGIPVVPGSDGGVTDEVEAARIAKEIGYPVIIKASAGGGGRGMKVARSAEELPIAL 188 Query: 183 PQAQAEALAAFGDGGLYVEKLIEGARHIEVQVLGDGR-DVIHCFERECSLQRRRQKVWEE 241 A++EA AAFGD +Y+EK +E RHIEVQV+GDG + +H ER+CSLQRR QKVWEE Sbjct: 189 ATARSEAGAAFGDDAVYIEKYLEKPRHIEVQVMGDGAGNAVHLGERDCSLQRRHQKVWEE 248 Query: 242 APSPSLTQAVRER---LCSSAVALARAVNYRGAGTLEYLYDDATGEFYFLEMNTRIQVEH 298 SP+L RE+ +C++A A + YRGAGT+E+LY+D GEFYF+EMNTR+QVEH Sbjct: 249 GNSPALNAEAREKIGMICANACA---ELGYRGAGTIEFLYED--GEFYFIEMNTRLQVEH 303 Query: 299 PVTEMITGIDLVREMIQIAGGERLRISQNEMRVSGHSIEVRINAEDPARNFLPNPGTVSA 358 PVTE ITGIDLV E I++A G L + Q ++R SGH+IE RINAEDP F P+PG ++ Sbjct: 304 PVTEAITGIDLVHEQIRVAAGLGLSVKQKDIRFSGHAIECRINAEDPL-TFAPSPGLITH 362 Query: 359 LSLPVGDGVRFDSMLYQGYTVPPFYDSLLGKLIVHDKDRPSAMKKLERALAELTVGGIFT 418 P G GVR DS +Y GY +PP+YDSL GKLIVH ++R M +L RAL E V G+ T Sbjct: 363 YHTPGGLGVRVDSGVYSGYRIPPYYDSLTGKLIVHGRNRVECMMRLRRALDEFVVDGVKT 422 Query: 419 TKPLHQALARDADVKAGRFHTAWLEPWL 446 T PL Q L + D+ G + WLE +L Sbjct: 423 TLPLFQDLISNQDIANGDYDIHWLEKYL 450 >alr0939 [I] COG0439 Biotin carboxylase Nos Nostoc sp. PCC 7120 Length = 447 Score = 488 bits (1255), Expect = e-137, Method: Compositional matrix adjust. Identities = 240/444 (54%), Positives = 320/444 (72%), Gaps = 2/444 (0%) Query: 1 MAIKKLLIANRGEIAVRIIRAARDLGIATVQVYSKADQDSLAVRLADEAVDIGPPQASKS 60 M K+LIANRGEIA+RI+RA ++GIAT+ V+S D+++L V+LADEAV IG P ++KS Sbjct: 1 MKFDKILIANRGEIALRILRACEEMGIATIAVHSTVDRNALHVQLADEAVCIGEPASAKS 60 Query: 61 YLNQAAILAAARSTGADAIHPGYGFLAENAEFAAAVEAAGLIFVGPTARSIRLMGDKVAA 120 YLN I+AAA + A AIHPGYGFL+ENA+FA + F+GPT +IRLMGDK A Sbjct: 61 YLNIPNIIAAALTRNASAIHPGYGFLSENAKFAEICADHHIAFIGPTPEAIRLMGDKSTA 120 Query: 121 REAAAAAGVPTVPGSQGRLESAEAAFALVEKTGFPVMIKAAAGGGGRGIRIARSPEEFQH 180 +E AGVPTVPGS+G +E+ + L + G+PVMIKA AGGGGRG+R+ RSP+EF Sbjct: 121 KETMQKAGVPTVPGSEGLVETEQEGLELAKDIGYPVMIKATAGGGGRGMRLVRSPDEFVK 180 Query: 181 LMPQAQAEALAAFGDGGLYVEKLIEGARHIEVQVLGDGR-DVIHCFERECSLQRRRQKVW 239 L AQ EA AAFG+ G+Y+EK IE RHIE Q+L D +VIH ER+CS+QRR QK+ Sbjct: 181 LFLAAQGEAGAAFGNAGVYIEKFIERPRHIEFQILADNYGNVIHLGERDCSIQRRNQKLL 240 Query: 240 EEAPSPSLTQAVRERLCSSAVALARAVNYRGAGTLEYLYDDATGEFYFLEMNTRIQVEHP 299 EEAPSP+L +RE++ +AV A+ +NY GAGT+E+L D +G+FYF+EMNTRIQVEHP Sbjct: 241 EEAPSPALDSDLREKMGQAAVKAAQFINYTGAGTIEFLL-DRSGQFYFMEMNTRIQVEHP 299 Query: 300 VTEMITGIDLVREMIQIAGGERLRISQNEMRVSGHSIEVRINAEDPARNFLPNPGTVSAL 359 VTEM+TG+DL+ E I+IA GERLR++Q+++ + GH+IE RINAEDP +F P PG +S Sbjct: 300 VTEMVTGVDLLVEQIRIAQGERLRLTQDQVVLRGHAIECRINAEDPDHDFRPAPGRISGY 359 Query: 360 SLPVGDGVRFDSMLYQGYTVPPFYDSLLGKLIVHDKDRPSAMKKLERALAELTVGGIFTT 419 P G GVR DS +Y Y +PP+YDSL+GKLIV DR +A+ +++RAL E + G+ TT Sbjct: 360 LPPGGPGVRIDSHVYTDYQIPPYYDSLIGKLIVWGPDRATAINRMKRALRECAITGLPTT 419 Query: 420 KPLHQALARDADVKAGRFHTAWLE 443 HQ + + G T++++ Sbjct: 420 IGFHQRIMENPQFLQGNVSTSFVQ 443 >SMc01345 [I] COG0439 Biotin carboxylase Sme Sinorhizobium meliloti Length = 449 Score = 486 bits (1251), Expect = e-137, Method: Compositional matrix adjust. Identities = 244/450 (54%), Positives = 321/450 (71%), Gaps = 5/450 (1%) Query: 3 IKKLLIANRGEIAVRIIRAARDLGIATVQVYSKADQDSLAVRLADEAVDIGPPQASKSYL 62 I K+LIANRGEIA+R++RA ++LGIATV V+S AD D++ VRLADE+V IGPP + +SYL Sbjct: 4 ISKILIANRGEIALRVLRACKELGIATVAVHSTADSDAMHVRLADESVCIGPPPSRESYL 63 Query: 63 NQAAILAAARSTGADAIHPGYGFLAENAEFAAAVEAAGLIFVGPTARSIRLMGDKVAARE 122 N I+AA TGADA+HPGYGFL+ENA+FA ++A G+ F+GPTA IRLMGDK+ A++ Sbjct: 64 NIHQIVAACEITGADAVHPGYGFLSENAKFADILDAHGITFIGPTAEHIRLMGDKITAKK 123 Query: 123 AAAAAGVPTVPGSQGRLESAEAAFALVEKTGFPVMIKAAAGGGGRGIRIARSPEEFQHLM 182 A G+P VPGS G + E A + + GFPV+IKA AGGGGRG+++AR+ EE ++ + Sbjct: 124 TAEELGIPVVPGSDGEVRP-ENALEIARQIGFPVLIKATAGGGGRGMKVARTEEELENAV 182 Query: 183 PQAQAEALAAFGDGGLYVEKLIEGARHIEVQVLGDGR-DVIHCFERECSLQRRRQKVWEE 241 A++EA AAFG+ +Y+EK + RHIE+QV+GDG + IH ER+CSLQRR QKVWEE Sbjct: 183 ATARSEAAAAFGNDAVYMEKFLGKPRHIEIQVVGDGEGNAIHLGERDCSLQRRHQKVWEE 242 Query: 242 APSPSLTQAVRERLCSSAVALARAVNYRGAGTLEYLYDDATGEFYFLEMNTRIQVEHPVT 301 A SP+L R ++ + + YRGAGT+E+LY++ GEFYF+EMNTR+QVEHP+T Sbjct: 243 ANSPALNVEQRMKIGQVCADAMKKLKYRGAGTIEFLYEN--GEFYFIEMNTRLQVEHPIT 300 Query: 302 EMITGIDLVREMIQIAGGERLRISQNEMRVSGHSIEVRINAEDPARNFLPNPGTVSALSL 361 E ITGIDLV E I++A G L Q ++ SGH+IE RINAEDP R F+P+PGT++ Sbjct: 301 EAITGIDLVHEQIRVASGAGLSAKQEDIVFSGHAIECRINAEDP-RTFVPSPGTITHFHA 359 Query: 362 PVGDGVRFDSMLYQGYTVPPFYDSLLGKLIVHDKDRPSAMKKLERALAELTVGGIFTTKP 421 P G GVR DS YQGY +PP+YDSL+GKLIVH + R M +L R L E + GI TT P Sbjct: 360 PGGLGVRVDSGAYQGYRIPPYYDSLIGKLIVHGRTRVECMMRLRRVLDEFVIDGIKTTLP 419 Query: 422 LHQALARDADVKAGRFHTAWLEPWLESHAA 451 L Q L + D+ G + WLE L + +A Sbjct: 420 LFQDLINNQDIANGDYDIHWLEHHLATTSA 449 >AGc2451 [I] COG0439 Biotin carboxylase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 448 Score = 481 bits (1239), Expect = e-135, Method: Compositional matrix adjust. Identities = 240/450 (53%), Positives = 324/450 (72%), Gaps = 5/450 (1%) Query: 3 IKKLLIANRGEIAVRIIRAARDLGIATVQVYSKADQDSLAVRLADEAVDIGPPQASKSYL 62 + K+LIANRGEIA+R++RAA++LGI TV V+S AD D++ VRLADE+V IGPP + SYL Sbjct: 2 VSKILIANRGEIALRVLRAAKELGIPTVAVHSTADADAMHVRLADESVCIGPPPSRDSYL 61 Query: 63 NQAAILAAARSTGADAIHPGYGFLAENAEFAAAVEAAGLIFVGPTARSIRLMGDKVAARE 122 N I+AA TGADA+HPGYGFL+ENA+FA ++A G+ F+GPTA IR+MGDK+ A++ Sbjct: 62 NIHQIVAACEITGADAVHPGYGFLSENAKFADILDAHGITFIGPTAEHIRIMGDKITAKQ 121 Query: 123 AAAAAGVPTVPGSQGRLESAEAAFALVEKTGFPVMIKAAAGGGGRGIRIARSPEEFQHLM 182 A G+P VPGS G ++ E A + GFPV+IKA AGGGGRG+++A++ + + + Sbjct: 122 TAQELGIPVVPGSDGEVKP-ENALEIARTIGFPVLIKATAGGGGRGMKVAKTEADLEDAV 180 Query: 183 PQAQAEALAAFGDGGLYVEKLIEGARHIEVQVLGDGR-DVIHCFERECSLQRRRQKVWEE 241 A++EA AAFG+ +Y+EK + RHIEVQV GDG + +H ER+CSLQRR QKV EE Sbjct: 181 ATARSEAAAAFGNDAVYMEKYLGKPRHIEVQVFGDGEGNAVHLGERDCSLQRRHQKVLEE 240 Query: 242 APSPSLTQAVRERLCSSAVALARAVNYRGAGTLEYLYDDATGEFYFLEMNTRIQVEHPVT 301 A SP+LT R ++ R + YRGAGT+E+LY++ GEFYF+EMNTR+QVEHPVT Sbjct: 241 ANSPALTVEQRMKIGEICADAMRKLKYRGAGTIEFLYEN--GEFYFIEMNTRLQVEHPVT 298 Query: 302 EMITGIDLVREMIQIAGGERLRISQNEMRVSGHSIEVRINAEDPARNFLPNPGTVSALSL 361 E ITG+DLV+E I++A G+ L ++Q ++ GH+IE RINAEDP R F+P+PGT++ Sbjct: 299 EAITGMDLVQEQIRVASGQGLSVTQADIEFHGHAIECRINAEDP-RTFVPSPGTLTYFHT 357 Query: 362 PVGDGVRFDSMLYQGYTVPPFYDSLLGKLIVHDKDRPSAMKKLERALAELTVGGIFTTKP 421 P G GVR DS YQGY +PP+YDS++GKLIVH +DR +++L RAL E V GI TT P Sbjct: 358 PGGLGVRVDSGAYQGYKIPPYYDSMIGKLIVHGRDRDECIRRLRRALDEFVVDGIKTTLP 417 Query: 422 LHQALARDADVKAGRFHTAWLEPWLESHAA 451 L Q L ++ D+ G + WLE +L A+ Sbjct: 418 LFQDLLQNEDILNGDYDIHWLEKYLAGDAS 447