BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0055.0001.p (199 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA0415 [IQR] COG1028 Dehydrogenases with different specificities... 161 8e-40 YPO1452 [IQR] COG1028 Dehydrogenases with different specificitie... 152 5e-37 mlr7055 [IQR] COG1028 Dehydrogenases with different specificitie... 152 5e-37 BS_ywfD [IQR] COG1028 Dehydrogenases with different specificitie... 145 6e-35 mlr3100 [IQR] COG1028 Dehydrogenases with different specificitie... 145 6e-35 >MA0415 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mac Methanosarcina acetivorans str.C2A Length = 256 Score = 161 bits (408), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 82/188 (43%), Positives = 117/188 (62%), Gaps = 5/188 (2%) Query: 11 EVKDYVRAAVDRFGTIDAFYNNAGVEGDIRPIPEYSLESFRRVLDVNVVGVFLGMKHVLP 70 +VK+ + + FG +D +NNAG+EG EY +E + RV+ N+ GVFL MK+ +P Sbjct: 73 DVKNAIEKIIQTFGQLDYAFNNAGIEGKTVITAEYPVEEWNRVIATNLTGVFLCMKYEIP 132 Query: 71 VMLKQNKGSIINTASIAGLVGSPMIAVYSASKHAVIGLTKSAAWECTGTGVRVNCVCPGM 130 MLKQ G+I+N +S AGL G P I+ Y ASKH V+GLTK+AA + + +R+N VCPGM Sbjct: 133 QMLKQGAGAIVNCSSGAGLTGFPDISPYVASKHGVVGLTKTAALDYAKSNIRINAVCPGM 192 Query: 131 IESRMLSTILQGRSGGNAPPPIEKIVDRIPARRLGLASEVASIVAFLASDEASYVSGSAY 190 ++ M+ R G P EKI+++ P R+G E+A V +L SD AS+V+G Sbjct: 193 TDTPMME-----RYSGGTPEGYEKIIEQEPIGRMGRPEEIAIAVLWLCSDAASFVTGDVM 247 Query: 191 TVDGGRTA 198 VDGG+ A Sbjct: 248 RVDGGQLA 255 >YPO1452 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ype Yersinia pestis Length = 248 Score = 152 bits (384), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 78/192 (40%), Positives = 113/192 (58%), Gaps = 5/192 (2%) Query: 7 STAXEVKDYVRAAVDRFGTIDAFYNNAGVEGDIRPIPEYSLESFRRVLDVNVVGVFLGMK 66 ++ ++K + ++RFG++D N AG G+ I + ++F V + NV+G L MK Sbjct: 61 NSESDIKHLIEMTLERFGSLDVAVNCAGTVGETAEIQAVTQDNFHLVFNTNVLGTLLAMK 120 Query: 67 HVLPVMLKQNKGSIINTASIAGLVGSPMIAVYSASKHAVIGLTKSAAWECTGTGVRVNCV 126 + +PVM+++ KGSIIN +SIAGLVG P +Y ASKHA+ GLTK+AA E TGVR+N + Sbjct: 121 YQIPVMVERGKGSIINISSIAGLVGLPSTGIYVASKHAIEGLTKTAALEVATTGVRINSI 180 Query: 127 CPGMIESRMLSTILQGRSGGNAPPPIEKIVDRIPARRLGLASEVASIVAFLASDEASYVS 186 PG +E +M L G N IE +P +R EVA + FLA D + ++ Sbjct: 181 SPGPVEGKMFDRFL-GHDENNKKAFIE----MMPNKRFTTQEEVAHTIVFLAEDNVTAIT 235 Query: 187 GSAYTVDGGRTA 198 G T+DGG TA Sbjct: 236 GQTITIDGGYTA 247 >mlr7055 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 248 Score = 152 bits (384), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 85/188 (45%), Positives = 112/188 (59%), Gaps = 6/188 (3%) Query: 11 EVKDYVRAAVDRFGTIDAFYNNAGVEGDIRPIPEYSLESFRRVLDVNVVGVFLGMKHVLP 70 EV+D + AV RFG +D NNAG EG P+ E + E++ D NV+G L +KH L Sbjct: 66 EVRDLIDRAVARFGRLDVAVNNAGTEGKPGPVTEQTAETYAATFDTNVLGTLLSLKHELR 125 Query: 71 VMLKQNKGSIINTASIAGLVGSPMIAVYSASKHAVIGLTKSAAWECTGTGVRVNCVCPGM 130 +ML Q GSI+N +S G G+ ++Y+ASKHAV GLTKSAA E +GVRVN V PG Sbjct: 126 IMLTQGGGSIVNISSTYGHEGAKGASIYAASKHAVEGLTKSAALEAAASGVRVNAVAPGP 185 Query: 131 IESRMLSTILQGRSGGNAPPPIEKIVDRIPARRLGLASEVASIVAFLASDEASYVSGSAY 190 + ML G S A + +P R+G SE+A + FLAS EAS+++G Sbjct: 186 TNTGMLDR-FTGTSEVKASLALT-----VPMGRVGQPSELARAIVFLASKEASFITGHVL 239 Query: 191 TVDGGRTA 198 TVDGG+TA Sbjct: 240 TVDGGKTA 247 >BS_ywfD [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bsu Bacillus subtilis Length = 255 Score = 145 bits (366), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 84/185 (45%), Positives = 114/185 (61%), Gaps = 5/185 (2%) Query: 16 VRAAVDRFGTIDAFYNNAGVEGDIRPIPEYSLESFRRVLDVNVVGVFLGMKHVLPVMLKQ 75 V +AV FG +D NNAG+E + PI E L + +VL VN+ G+FL KH L ML Sbjct: 73 VESAVHTFGGLDVLINNAGIE-IVAPIHEMELSDWNKVLQVNLTGMFLMSKHALKHMLAA 131 Query: 76 NKGSIINTASIAGLVGSPMIAVYSASKHAVIGLTKSAAWECTGTGVRVNCVCPGMIESRM 135 KG+IINT S+ GLV P I Y+ASK V+ LTKS A + +RVNCVCPG+I++ + Sbjct: 132 GKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCPGIIDTPL 191 Query: 136 -LSTILQGRSGGNAPPPIEKIVDRI-PARRLGLASEVASIVAFLASDEASYVSGSAYTVD 193 + L+ G I+K ++ P RLG E+A+++ FLASD +SY++GSA T D Sbjct: 192 NEKSFLENNEG--TLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYMTGSAITAD 249 Query: 194 GGRTA 198 GG TA Sbjct: 250 GGYTA 254 >mlr3100 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 258 Score = 145 bits (365), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 72/188 (38%), Positives = 116/188 (61%), Gaps = 6/188 (3%) Query: 13 KDYVRAAVDRFGTIDAFYNNAGVEGDIRPIPEYSLESFRRVLDVNVVGVFLGMKHVLPVM 72 +D VR AV++FG +D NNAG+ +P+ + RRVL+++++GVF MKH +P M Sbjct: 68 EDLVRLAVEKFGRLDVTVNNAGIVQSFVRLPQVPSDEARRVLEIDLLGVFYAMKHQIPQM 127 Query: 73 LKQNK-----GSIINTASIAGLVGSPMIAVYSASKHAVIGLTKSAAWECTGTGVRVNCVC 127 +Q + G+I+N AS+AGLVG+P ++VY+A+KH V+GLTKSAA E GVR+N +C Sbjct: 128 ERQFRATAKGGAIVNIASVAGLVGAPKLSVYAAAKHGVVGLTKSAAAEYATKGVRINAIC 187 Query: 128 PGMIESRMLSTILQGRSGGNAPPPIEKIVDRIPARRLGLASEVASIVAFLASDEASYVSG 187 P + M+ + ++ SG + ++ +P +R+ E+ + + F A S+++G Sbjct: 188 PAHTRTAMVDSFVRA-SGAPEAEALAELTRGVPMKRVAEVDEITTAILFAADPANSFMTG 246 Query: 188 SAYTVDGG 195 A VDGG Sbjct: 247 HALAVDGG 254