BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0054.0027.p (434 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr5554 [J] COG0532 Translation initiation factor 2 (IF-2 GTPas... 516 e-146 BMEI1965 [J] COG0532 Translation initiation factor 2 (IF-2 GTPa... 514 e-145 SMc02914 [J] COG0532 Translation initiation factor 2 (IF-2 GTPa... 510 e-144 AGc131 [J] COG0532 Translation initiation factor 2 (IF-2 GTPase... 501 e-141 CC0042 [J] COG0532 Translation initiation factor 2 (IF-2 GTPase... 451 e-126 >mlr5554 [J] COG0532 Translation initiation factor 2 (IF-2 GTPase) Mlo Length = 860 Score = 516 bits (1328), Expect = e-146, Method: Compositional matrix adjust. Identities = 264/404 (65%), Positives = 323/404 (79%), Gaps = 2/404 (0%) Query: 11 VAAPKTTHKPGPQKQRGRLTVVTALNADDVRERSIASFRRRTQRLKGHAANEQKEKLIRE 70 VA P K ++RG+LT+ +AL+ +D R RS++S RRR ++ K NE +EK++RE Sbjct: 219 VARPAKPTKGEEDRRRGKLTLNSALSDEDARARSLSSMRRRQEKFKRAMHNEPREKVMRE 278 Query: 71 VVIPEVIAIQELANRMSERAVDVIRMLMKQGAMHKITDVIDADTAQLIAEELGHTVKRVA 130 V++PE I IQELA RMSERAVDV++ MKQG + K DVIDADTA+L+A E GHTV+RVA Sbjct: 279 VILPETITIQELAQRMSERAVDVVKFFMKQGQILKPGDVIDADTAELVATEFGHTVRRVA 338 Query: 131 ASDVEEGLFDVVDDSTDTEPRSPVVTVMGHVDHGKTSLLDALRHANVVSGEAGGITQHIG 190 SD+EEGLF++ D++ D PR PVVT+MGHVDHGKTSLLDA+R+ANVVSGEAGGITQHIG Sbjct: 339 ESDIEEGLFNIADNAEDLVPRPPVVTIMGHVDHGKTSLLDAIRNANVVSGEAGGITQHIG 398 Query: 191 AYQVLSPESGTKITFIDTPGHAAFTAMRARGAKVTDIVVLVVAADDGVMPQTIEAINHAK 250 AYQV ++G KITFIDTPGHAAFTAMRARGA+ TDI +LVVAADD VMPQTIE+I+HAK Sbjct: 399 AYQV--EKNGQKITFIDTPGHAAFTAMRARGAQATDIAILVVAADDSVMPQTIESISHAK 456 Query: 251 AAKVPMIVAINKIDKPDARPERVRTELLQHEVQVESLGGDVVDVEVSAKNKTNLDRLLEM 310 AA VP+IVAINKIDK DA P++VR+ELL+HEV VES+GG+V+DVEVSA TNLD+LLE Sbjct: 457 AAGVPIIVAINKIDKHDADPQKVRSELLRHEVFVESMGGEVLDVEVSATKGTNLDKLLEA 516 Query: 311 IALQAEILDLKTNSQRPAEGTVIEAKLDRGRGPVATVLVQRGTLRIGDIIVAGAEMGRVR 370 I LQAEILDLK N R AEG VIEA+LD+GRGPVATVLVQ GTL GDI+VAG E GRVR Sbjct: 517 ILLQAEILDLKANPDRTAEGVVIEAQLDKGRGPVATVLVQTGTLMPGDILVAGNEWGRVR 576 Query: 371 ALISDQGENLEEAGPSVPVXRKPATVSPLSRTKPAPARSRATAR 414 AL++D+GE ++EA P++PV +PL+ + A + A AR Sbjct: 577 ALVNDRGEQIKEAPPAMPVEVLGLQGTPLAGDRFAVVNNEARAR 620 >BMEI1965 [J] COG0532 Translation initiation factor 2 (IF-2 GTPase) Bme Length = 733 Score = 514 bits (1324), Expect = e-145, Method: Compositional matrix adjust. Identities = 264/388 (68%), Positives = 319/388 (82%), Gaps = 5/388 (1%) Query: 3 RPGGAVRP-VAAPKTTHKPGPQKQRGRLTVVTALNADDVRERSIASFRRRTQRLKGHAAN 61 R G A +P V APK K ++RG+LT+ + L ++ R RS+++ RRR ++ K Sbjct: 85 RRGVAAKPEVRAPKVV-KGEDDRRRGKLTLTSNLE-EEGRSRSLSAMRRRQEKFKRSQMQ 142 Query: 62 EQKEKLIREVVIPEVIAIQELANRMSERAVDVIRMLMKQGAMHKITDVIDADTAQLIAEE 121 E +EK+ REV IPE I +QELA RM+ER+VD+I+ LMKQG M K DVIDADTAQLIAEE Sbjct: 143 ETREKISREVTIPETITLQELAQRMAERSVDIIKYLMKQGQMMKPGDVIDADTAQLIAEE 202 Query: 122 LGHTVKRVAASDVEEGLFDVVDDSTDTEPRSPVVTVMGHVDHGKTSLLDALRHANVVSGE 181 GHTVKRVA SDVEEG+FDV D+ + R PVVT+MGHVDHGKTSLLDA+RHANVVSGE Sbjct: 203 FGHTVKRVAESDVEEGIFDVADNESAMVSRPPVVTIMGHVDHGKTSLLDAIRHANVVSGE 262 Query: 182 AGGITQHIGAYQVLSPESGTKITFIDTPGHAAFTAMRARGAKVTDIVVLVVAADDGVMPQ 241 AGGITQHIGAYQV+ ++G KITFIDTPGHAAFTAMRARGA+ TDI +LVVAADD VMPQ Sbjct: 263 AGGITQHIGAYQVV--QNGQKITFIDTPGHAAFTAMRARGAQATDIAILVVAADDSVMPQ 320 Query: 242 TIEAINHAKAAKVPMIVAINKIDKPDARPERVRTELLQHEVQVESLGGDVVDVEVSAKNK 301 TIE+INHAKAA VP+IVAINKIDKP A P++VRT LLQHEV VES+GG+V+DVEVSAKNK Sbjct: 321 TIESINHAKAAGVPIIVAINKIDKPAADPQKVRTALLQHEVFVESMGGEVLDVEVSAKNK 380 Query: 302 TNLDRLLEMIALQAEILDLKTNSQRPAEGTVIEAKLDRGRGPVATVLVQRGTLRIGDIIV 361 NLD+LL+ + LQAE+LDLK + R AEG VIEA+LDRGRG VATVL+Q+GTL GDI+V Sbjct: 381 INLDKLLDAVLLQAEMLDLKADPDRTAEGVVIEAQLDRGRGSVATVLIQKGTLHPGDILV 440 Query: 362 AGAEMGRVRALISDQGENLEEAGPSVPV 389 AG+E GRVRAL++D+GE+++EAGP++PV Sbjct: 441 AGSEWGRVRALVNDRGEHVKEAGPAMPV 468 >SMc02914 [J] COG0532 Translation initiation factor 2 (IF-2 GTPase) Sme Length = 889 Score = 510 bits (1313), Expect = e-144, Method: Compositional matrix adjust. Identities = 274/432 (63%), Positives = 331/432 (76%), Gaps = 6/432 (1%) Query: 5 GGAVRPV-AAPKTTHKPGPQKQRGRLTVVTALNADD--VRERSIASFRRRTQRLKGHAAN 61 G VRP A P K +++G+LT+ TA +D R RS+++ RRR ++ K Sbjct: 239 GKVVRPEPAKPAPRAKGDEGRRQGKLTLTTAAVDEDGSQRGRSLSAMRRRQEKFKRSQMQ 298 Query: 62 EQKEKLIREVVIPEVIAIQELANRMSERAVDVIRMLMKQGAMHKITDVIDADTAQLIAEE 121 E +EK+ REVV+PE I IQEL+ RMSERAVDVI+ LMK+G M K D+IDAD A+LIA E Sbjct: 299 ETREKISREVVLPETITIQELSQRMSERAVDVIKFLMKEGQMMKPGDLIDADLAELIAGE 358 Query: 122 LGHTVKRVAASDVEEGLFDVVDDSTDTEPRSPVVTVMGHVDHGKTSLLDALRHANVVSGE 181 GHTVKRV+ SDVEEG+F++ D D + R P+VT+MGHVDHGKTSLLDA+RHANVV+GE Sbjct: 359 FGHTVKRVSESDVEEGIFNISDVDDDMQSRPPIVTIMGHVDHGKTSLLDAIRHANVVAGE 418 Query: 182 AGGITQHIGAYQVLSPESGTKITFIDTPGHAAFTAMRARGAKVTDIVVLVVAADDGVMPQ 241 AGGITQHIGAYQV ++G KITFIDTPGHAAFTAMRARGA+ TDI VLVVAADD VMPQ Sbjct: 419 AGGITQHIGAYQV--EQNGQKITFIDTPGHAAFTAMRARGAQATDIAVLVVAADDSVMPQ 476 Query: 242 TIEAINHAKAAKVPMIVAINKIDKPDARPERVRTELLQHEVQVESLGGDVVDVEVSAKNK 301 TIE+INHAKAA VP+IVAINKIDKP A P++VRTELLQHEV VES+GG+V+DVEVSAKN+ Sbjct: 477 TIESINHAKAAGVPIIVAINKIDKPSANPQKVRTELLQHEVFVESMGGEVLDVEVSAKNQ 536 Query: 302 TNLDRLLEMIALQAEILDLKTNSQRPAEGTVIEAKLDRGRGPVATVLVQRGTLRIGDIIV 361 TNLD+LLE I LQ+EILDLK N R AEGTV+EA+LDRGRG VATVLVQ+GTL G IIV Sbjct: 537 TNLDKLLEAILLQSEILDLKANPNRTAEGTVVEAELDRGRGAVATVLVQKGTLTPGQIIV 596 Query: 362 AGAEMGRVRALISDQGENLEEAGPSVPVXRKPATVSPLSRTKPAPARSRATARTRS-ART 420 AG + GRVRAL++D+GE+++ AGPS PV + +P + + A S + AR S R Sbjct: 597 AGDQWGRVRALVNDKGEHVKAAGPSTPVEVLGLSGTPAAGDRFAVVESESRAREISEYRQ 656 Query: 421 LLPRFPACAARS 432 L R A A +S Sbjct: 657 RLAREKAVARQS 668 >AGc131 [J] COG0532 Translation initiation factor 2 (IF-2 GTPase) Atu Length = 913 Score = 501 bits (1291), Expect = e-141, Method: Compositional matrix adjust. Identities = 255/372 (68%), Positives = 307/372 (82%), Gaps = 3/372 (0%) Query: 19 KPGPQKQRGRLTVVTALNADDV-RERSIASFRRRTQRLKGHAANEQKEKLIREVVIPEVI 77 K +++RG+LTV + L D R RS+AS RRR ++ + E +EK++REV++PE I Sbjct: 279 KTEEERRRGKLTVTSNLEEDGTPRGRSMASMRRRQEKFRRSQMQETREKVLREVILPETI 338 Query: 78 AIQELANRMSERAVDVIRMLMKQGAMHKITDVIDADTAQLIAEELGHTVKRVAASDVEEG 137 IQEL+ RMSERAVDVI+ LMK+G M K DVIDAD A+LIA E GHTVKRV+ SDVEEG Sbjct: 339 TIQELSQRMSERAVDVIKFLMKEGQMLKPGDVIDADLAELIAVEFGHTVKRVSESDVEEG 398 Query: 138 LFDVVDDSTDTEPRSPVVTVMGHVDHGKTSLLDALRHANVVSGEAGGITQHIGAYQVLSP 197 +F+ DD + R PVVT+MGHVDHGKTSLLDA+R ANVVSGEAGGITQHIGAYQV Sbjct: 399 IFNQTDDEGEMVSRPPVVTIMGHVDHGKTSLLDAIRQANVVSGEAGGITQHIGAYQV--E 456 Query: 198 ESGTKITFIDTPGHAAFTAMRARGAKVTDIVVLVVAADDGVMPQTIEAINHAKAAKVPMI 257 ++G KITFIDTPGHAAFTAMRARGA+ TDI VLVVAADD VMPQTIE+INHAKAA VP++ Sbjct: 457 KNGHKITFIDTPGHAAFTAMRARGAQATDIAVLVVAADDSVMPQTIESINHAKAAGVPIV 516 Query: 258 VAINKIDKPDARPERVRTELLQHEVQVESLGGDVVDVEVSAKNKTNLDRLLEMIALQAEI 317 VAINKIDK +A P++VR +LLQHEV VES+GG+V+DVEVSAKNK NLD+LLE I LQAEI Sbjct: 517 VAINKIDKHEANPDKVRQQLLQHEVFVESMGGEVLDVEVSAKNKLNLDKLLEAILLQAEI 576 Query: 318 LDLKTNSQRPAEGTVIEAKLDRGRGPVATVLVQRGTLRIGDIIVAGAEMGRVRALISDQG 377 LDLK + R AEGTVIEA+LDRGRG VATVLVQ+GTL+ G IIVAG + GRVRAL++D+G Sbjct: 577 LDLKADPSRTAEGTVIEAELDRGRGAVATVLVQKGTLKPGQIIVAGDQWGRVRALVNDKG 636 Query: 378 ENLEEAGPSVPV 389 ++++EAGP++PV Sbjct: 637 DHVKEAGPAMPV 648 >CC0042 [J] COG0532 Translation initiation factor 2 (IF-2 GTPase) Ccr Length = 1037 Score = 451 bits (1159), Expect = e-126, Method: Compositional matrix adjust. Identities = 235/377 (62%), Positives = 289/377 (76%), Gaps = 9/377 (2%) Query: 19 KPGPQKQRGRLTVVTALNADDV--RERSIASFRRRTQRLK----GHAANEQKEKLIREVV 72 K PQ++ GRLT+ D R RS+AS RR +R K G A ++ ++ REVV Sbjct: 398 KGAPQRREGRLTIQAVAGDGDSADRMRSLASVRRAREREKEKRRGGAV--EQARVAREVV 455 Query: 73 IPEVIAIQELANRMSERAVDVIRMLMKQGAMHKITDVIDADTAQLIAEELGHTVKRVAAS 132 IP+VI +QEL+NRM+ R VD+I+ LM+QG M KI DVID DTA+L+A E GHTVKRV+ + Sbjct: 456 IPDVITVQELSNRMAVRGVDIIKFLMRQGVMLKINDVIDNDTAELVATEFGHTVKRVSEA 515 Query: 133 DVEEGLFDVVDDSTDTEPRSPVVTVMGHVDHGKTSLLDALRHANVVSGEAGGITQHIGAY 192 DVEEG D + R PVVT+MGHVDHGKTSLLDALR +V +GEAGGITQHIGAY Sbjct: 516 DVEEGFIGADDHDEHMDLRPPVVTIMGHVDHGKTSLLDALRSTDVAAGEAGGITQHIGAY 575 Query: 193 QVLSPESGTKITFIDTPGHAAFTAMRARGAKVTDIVVLVVAADDGVMPQTIEAINHAKAA 252 QV + G ++TF+DTPGHAAF++MRARGA +TDIVVLVVA DDGVMPQTIEAI HAKAA Sbjct: 576 QVRL-KDGQRVTFLDTPGHAAFSSMRARGANITDIVVLVVAGDDGVMPQTIEAIKHAKAA 634 Query: 253 KVPMIVAINKIDKPDARPERVRTELLQHEVQVESLGGDVVDVEVSAKNKTNLDRLLEMIA 312 +VP+IVA+NK+DKP + P RV ELLQHE+ VESLGGD +EVSAK +T LD LLE I Sbjct: 635 EVPIIVAVNKMDKPGSDPTRVVNELLQHEIVVESLGGDTQLIEVSAKARTGLDNLLEAIL 694 Query: 313 LQAEILDLKTNSQRPAEGTVIEAKLDRGRGPVATVLVQRGTLRIGDIIVAGAEMGRVRAL 372 LQAE+LDLK N R A+G VIEAKLD+GRG V+TVLV RGTL+ GDI+VAG++ G+VRAL Sbjct: 695 LQAEVLDLKANPDRSADGVVIEAKLDKGRGAVSTVLVNRGTLKRGDIVVAGSQWGKVRAL 754 Query: 373 ISDQGENLEEAGPSVPV 389 ++++ E L+EAGP+ PV Sbjct: 755 LNERNEQLQEAGPATPV 771