BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0054.0003.p (293 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc01154 [L] COG0266 Formamidopyrimidine-DNA glycosylase Sme Sin... 358 1e-98 AGc561 [L] COG0266 Formamidopyrimidine-DNA glycosylase Atu Agrob... 342 6e-94 mll5585 [L] COG0266 Formamidopyrimidine-DNA glycosylase Mlo Meso... 337 2e-92 BMEI1946 [L] COG0266 Formamidopyrimidine-DNA glycosylase Bme Bru... 327 2e-89 CC3707 [L] COG0266 Formamidopyrimidine-DNA glycosylase Ccr Caulo... 298 1e-80 >SMc01154 [L] COG0266 Formamidopyrimidine-DNA glycosylase Sme Sinorhizobium meliloti Length = 301 Score = 358 bits (918), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 179/301 (59%), Positives = 211/301 (70%), Gaps = 8/301 (2%) Query: 1 MPELPEVETVRRGLQPAMEGSRILKAEARRKDLRFPFQKDFIARLEGRTITGLGRRAKYL 60 MPELPEVETV+RGL P MEG+ +++AE RR DLRFPF ++F + GR I L RRAKYL Sbjct: 1 MPELPEVETVKRGLAPTMEGALLVRAELRRPDLRFPFPENFANAVAGRRIIALSRRAKYL 60 Query: 61 MADLNSGDVLLMHLGMSGSFRVLK---QDGA--ATPGQFHHPRSEDRAHDHVVFHMSSG- 114 M +L GDV++ HLGMSGSFR+ K + GA ATPG FHHPR +D HDHVVFH+ G Sbjct: 61 MIELEGGDVIIAHLGMSGSFRIEKGPIEAGADPATPGAFHHPRGKDEKHDHVVFHLDGGS 120 Query: 115 --AAVVFNDPRRFGYMKIIARNAIEDEPLLKGLGPEPLGNEFDAAMLARSCHNKKTSLKA 172 A V++NDPRRFG+M + R+A+ D L+GLG EP GN DAA LA K LKA Sbjct: 121 GPARVIYNDPRRFGFMDLARRSALADHVFLRGLGEEPTGNALDAAYLATRFAGKIQPLKA 180 Query: 173 ALLDQRVVAGLGNIYVCEALFRSHLSPRRLAATLATKKAEPTDHARRLVDAIHSVLNQAI 232 ALLDQR +AGLGNIYVCEAL+RS LSP+R A TL K+ P L + I +V+ AI Sbjct: 181 ALLDQRTIAGLGNIYVCEALWRSGLSPKRSAGTLVDKRGRPKQALIALTERIRAVIADAI 240 Query: 233 KAGGSSISDHRLTNGDLGYFQHSFQVYDREGETCRTSGCEGIVKRFTQNGRSTFWCPKCQ 292 AGGSS+ DH +G LGYFQHSF VYDREGE CRT GC G V R Q GRSTF+CP CQ Sbjct: 241 AAGGSSLKDHIQADGSLGYFQHSFSVYDREGEACRTPGCHGTVARIVQAGRSTFYCPHCQ 300 Query: 293 K 293 K Sbjct: 301 K 301 >AGc561 [L] COG0266 Formamidopyrimidine-DNA glycosylase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 325 Score = 342 bits (877), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 167/298 (56%), Positives = 203/298 (68%), Gaps = 5/298 (1%) Query: 1 MPELPEVETVRRGLQPAMEGSRILKAEARRKDLRFPFQKDFIARLEGRTITGLGRRAKYL 60 MPELPEVETVRRGL PAMEG+R+ K R DLRFPF DF +EG+TI LGRRAKYL Sbjct: 28 MPELPEVETVRRGLAPAMEGARVRKLHLGRPDLRFPFPADFAGLIEGKTIISLGRRAKYL 87 Query: 61 MADLNSGDVLLMHLGMSGSFRVL--KQDGAATPGQFHHPRSEDRAHDHVVFHMSSG---A 115 + +L G ++ HLGMSGSFR+ K +G PG FH+ RS+D HDHVVFH+ G Sbjct: 88 LIELEDGLTIVSHLGMSGSFRIEAEKGEGGEAPGAFHYARSKDGKHDHVVFHLDKGEERV 147 Query: 116 AVVFNDPRRFGYMKIIARNAIEDEPLLKGLGPEPLGNEFDAAMLARSCHNKKTSLKAALL 175 V++NDPRRFG+M ++ RN ++ P LGPEP GN A LA K LK+ LL Sbjct: 148 CVIYNDPRRFGFMHLVERNKLDLYPAFAELGPEPTGNALSADYLASRFEGKSQPLKSTLL 207 Query: 176 DQRVVAGLGNIYVCEALFRSHLSPRRLAATLATKKAEPTDHARRLVDAIHSVLNQAIKAG 235 DQ+++AGLGNIYVCEAL+R+HLSP R A TL T + +P L + I V+ AI AG Sbjct: 208 DQKIIAGLGNIYVCEALWRAHLSPLRAAGTLVTTRGKPKAQLIDLTEKIRDVIADAIAAG 267 Query: 236 GSSISDHRLTNGDLGYFQHSFQVYDREGETCRTSGCEGIVKRFTQNGRSTFWCPKCQK 293 GSS+ DH T+G LGYFQHSF VYD+EG+ CRT GC G V+R Q GRSTF+C CQK Sbjct: 268 GSSLRDHIQTDGTLGYFQHSFSVYDQEGQPCRTPGCGGTVERVVQAGRSTFYCAACQK 325 >mll5585 [L] COG0266 Formamidopyrimidine-DNA glycosylase Mlo Mesorhizobium loti Length = 296 Score = 337 bits (864), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 168/296 (56%), Positives = 207/296 (69%), Gaps = 5/296 (1%) Query: 1 MPELPEVETVRRGLQPAMEGSRILKAEARRKDLRFPFQKDFIARLEGRTITGLGRRAKYL 60 MPELPEVETVRRGLQP +EG+R+ + EARR DLRFPF + F RL G+TIT LGRRAKYL Sbjct: 1 MPELPEVETVRRGLQPVLEGARLTRVEARRPDLRFPFPERFSERLTGKTITALGRRAKYL 60 Query: 61 MADLNSGDVLLMHLGMSGSFRVLKQDGAATPGQFHHPRSEDRAHDHVVFHMSSG----AA 116 + G VL+ HLGMSGSFR+ D TPG FHH RS+ AHDHVVF + + + Sbjct: 61 TMHVQDGPVLICHLGMSGSFRIETDDDGETPGVFHHERSKSTAHDHVVFDVVAADGARSR 120 Query: 117 VVFNDPRRFGYMKIIARNAIEDEPLLKGLGPEPLGNEFDAAMLARSCHNKKTSLKAALLD 176 V+FNDPRRFG+M + A + E P+L GLG EP GN D +LA + + LKAALLD Sbjct: 121 VIFNDPRRFGFM-LFAEGSPETHPMLAGLGVEPTGNTLDGVLLASLLKGRGSPLKAALLD 179 Query: 177 QRVVAGLGNIYVCEALFRSHLSPRRLAATLATKKAEPTDHARRLVDAIHSVLNQAIKAGG 236 Q+++AGLGNIYV EAL+R+ LSP R A T+A + + RL +AI SV++ AI AGG Sbjct: 180 QKLIAGLGNIYVSEALWRAGLSPLREAGTIARPSKKARQQSERLAEAIRSVISDAIAAGG 239 Query: 237 SSISDHRLTNGDLGYFQHSFQVYDREGETCRTSGCEGIVKRFTQNGRSTFWCPKCQ 292 SS+ D+ T+G LGYFQHSF VYDREGE C GC G ++R Q+GRSTF+C CQ Sbjct: 240 SSLRDYMHTDGSLGYFQHSFAVYDREGEPCPKPGCGGHIERVVQSGRSTFYCRTCQ 295 >BMEI1946 [L] COG0266 Formamidopyrimidine-DNA glycosylase Bme Brucella melitensis Length = 293 Score = 327 bits (838), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 163/296 (55%), Positives = 202/296 (68%), Gaps = 8/296 (2%) Query: 1 MPELPEVETVRRGLQPAMEGSRILKAEARRKDLRFPFQKDFIARLEGRTITGLGRRAKYL 60 MPELPEVETVRRGLQP MEG+ +++ E R DLRF F ++F RL GR I LGRRAKYL Sbjct: 1 MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYL 60 Query: 61 MADLNSGDVLLMHLGMSGSFRVLKQDGAATPGQFHHPRSEDRAHDHVVFHM----SSGAA 116 L+ G ++ HLGMSGSFR+ +D PG FHH RS++ HDHVVFH+ + A Sbjct: 61 TVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRPDGASAR 120 Query: 117 VVFNDPRRFGYMKIIARNAIEDEPLLKGLGPEPLGNEFDAAMLARSCHNKKTSLKAALLD 176 +++NDPRRFG+M + A+E+ PLLK LG EP GN +LA ++T LKAALLD Sbjct: 121 IIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLD 180 Query: 177 QRVVAGLGNIYVCEALFRSHLSPRRLAATLATKKAEPTDHARRLVDAIHSVLNQAIKAGG 236 QR++AGLGNIYVCEAL+R LSP R A ++A + D RL AI SV+ QAI AGG Sbjct: 181 QRLIAGLGNIYVCEALWRPGLSPMRAAGSVAGE----MDVMERLAGAIRSVIAQAIAAGG 236 Query: 237 SSISDHRLTNGDLGYFQHSFQVYDREGETCRTSGCEGIVKRFTQNGRSTFWCPKCQ 292 SS+ D+ +G LGYFQHSF VY REG+ CR C G V+R Q+GRSTF+C CQ Sbjct: 237 SSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQ 292 >CC3707 [L] COG0266 Formamidopyrimidine-DNA glycosylase Ccr Caulobacter vibrioides Length = 315 Score = 298 bits (763), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 145/292 (49%), Positives = 184/292 (63%), Gaps = 6/292 (2%) Query: 1 MPELPEVETVRRGLQPAMEGSRILKAEARRKDLRFPFQKDFIARLEGRTITGLGRRAKYL 60 +PELPEVETVRRGL+P + G+R+ A R DLRFP F+ RL G I L RRAKY+ Sbjct: 29 VPELPEVETVRRGLEPVLSGARLSSVRANRPDLRFPLPDGFVQRLTGARILRLDRRAKYI 88 Query: 61 MADLNSGDVLLMHLGMSGSFRVLKQDGAATPGQFHHPRSEDRAHDHVVFHMSSGAAVVFN 120 +A L+ GD L+MHLGM+G F + +G PG F + D H HVVF GA V + Sbjct: 89 LAPLDRGDTLVMHLGMTGRFEIAAPEGTVRPGDFAREVTPDDKHAHVVFQTEDGATVTYF 148 Query: 121 DPRRFGYMKIIARNAIEDEPLLKGLGPEPLGNEFDAAMLARSCHNKKTSLKAALLDQRVV 180 DPRRFG+M +I + + +GPEPLG FDA L ++ N+K K LLDQR V Sbjct: 149 DPRRFGFMDLIPTDRVSHHAWFAAMGPEPLGEGFDARTLEKAFANRKQGPKTLLLDQRTV 208 Query: 181 AGLGNIYVCEALFRSHLSPRRLAATLATKKAEPTDHARRLVDAIHSVLNQAIKAGGSSIS 240 AGLGNIYVCEAL RS +SP + + +A K+ P L AI VL +A++ GGS++ Sbjct: 209 AGLGNIYVCEALHRSGISPFKPSGNIAKKRLTP------LTAAIKDVLAEAVEVGGSTLK 262 Query: 241 DHRLTNGDLGYFQHSFQVYDREGETCRTSGCEGIVKRFTQNGRSTFWCPKCQ 292 D +G LGYFQH F+VYDREGE C T C+G++ R Q GRSTF+CP CQ Sbjct: 263 DFAAADGALGYFQHRFRVYDREGEPCPTPACKGVIAREVQAGRSTFFCPVCQ 314