BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0053.0004.p (218 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb21107 [MR] COG4948 L-alanine-DL-glutamate epimerase and relat... 136 3e-32 BMEI1712 [MR] COG4948 L-alanine-DL-glutamate epimerase and relat... 133 4e-31 mll7149 [MR] COG4948 L-alanine-DL-glutamate epimerase and relate... 129 3e-30 AGl3340 [MR] COG4948 L-alanine-DL-glutamate epimerase and relate... 109 5e-24 STM3697 [MR] COG4948 L-alanine-DL-glutamate epimerase and relate... 109 6e-24 >SMb21107 [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Sme Sinorhizobium meliloti Length = 370 Score = 136 bits (343), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 73/197 (37%), Positives = 106/197 (53%), Gaps = 1/197 (0%) Query: 17 QGFRGIKIKGGDGNAAIDERVVKGVRALLGPDIALMIDFNQSLDPAEATRRIARLAPYDL 76 GF G K+K G + A D + +RA LG +M D NQ EA RR ARL DL Sbjct: 160 NGFSGSKVKIGKPSGAEDYDRLSAMRAALGDGFEIMTDCNQGFTVDEAIRRAARLRELDL 219 Query: 77 HWIEEPVPQESLSGHAKVRETSPTPIQAGENWWFPRGFAEAIAAGASDFIMPDVMKVGGV 136 WIEEP+P + L GH ++ ++PTPI GE+ + R F E + GA + DV ++GG+ Sbjct: 220 AWIEEPLPADDLDGHIRLTRSTPTPIAVGESIYSIRHFREYMQKGACSIVQVDVARIGGI 279 Query: 137 TGWVQVAGQADAASIPMSSHLFAEVSAHLLAVTPTAHWLEFLDFAGSILTRPAEIVDG-A 195 T W++VA A+A IP+ H E+ L+ P ++E++ + EI +G A Sbjct: 280 TPWLKVAHAAEAFDIPVCPHFLMELHVSLVCAVPNGKYVEYIPQLDDLTQMGMEIREGRA 339 Query: 196 VTARGPGLGIEWNEPAV 212 + PG+GI W+ AV Sbjct: 340 IAPSNPGIGIAWDWEAV 356 >BMEI1712 [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Bme Brucella melitensis Length = 372 Score = 133 bits (334), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 72/197 (36%), Positives = 105/197 (53%), Gaps = 1/197 (0%) Query: 17 QGFRGIKIKGGDGNAAIDERVVKGVRALLGPDIALMIDFNQSLDPAEATRRIARLAPYDL 76 +GF G KIK G + A D + VRA +G +M D NQ EA RR RL DL Sbjct: 160 KGFTGSKIKIGKPHGAQDYARLSAVRAAVGAAFEIMTDCNQGFTVDEAIRRAERLKELDL 219 Query: 77 HWIEEPVPQESLSGHAKVRETSPTPIQAGENWWFPRGFAEAIAAGASDFIMPDVMKVGGV 136 WIEEP+P + L GH ++ ++ P+ GE+ + R F E + GA + DV ++GG+ Sbjct: 220 AWIEEPLPADDLDGHMRLARSTAAPVAVGESIYSIRHFREYMHKGACSIVQVDVARIGGI 279 Query: 137 TGWVQVAGQADAASIPMSSHLFAEVSAHLLAVTPTAHWLEFLDFAGSILTRPAEIVDG-A 195 T W++VA A+A IP+ H E+ L+ P ++E++ + + EI DG A Sbjct: 280 TPWLKVAHMAEAFDIPVCPHFLMELHVSLVCAVPNGRYVEYIPQLDDLTDKGMEIRDGHA 339 Query: 196 VTARGPGLGIEWNEPAV 212 V PG+GI W+ AV Sbjct: 340 VAPSQPGIGIAWDWDAV 356 >mll7149 [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Mlo Mesorhizobium loti Length = 370 Score = 129 bits (325), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 69/197 (35%), Positives = 106/197 (53%), Gaps = 1/197 (0%) Query: 17 QGFRGIKIKGGDGNAAIDERVVKGVRALLGPDIALMIDFNQSLDPAEATRRIARLAPYDL 76 +GFRG K+K G + + D + VR +G +M D NQ EA RR ARL DL Sbjct: 160 KGFRGSKVKIGRPHGSEDLARLSAVRKAVGDGYEIMTDANQGFSVDEAIRRAARLRELDL 219 Query: 77 HWIEEPVPQESLSGHAKVRETSPTPIQAGENWWFPRGFAEAIAAGASDFIMPDVMKVGGV 136 WIEEP+P + + GH ++ ++PTPI GE+ + R F E + GA + DV ++GG+ Sbjct: 220 AWIEEPLPADDIDGHIRLSNSTPTPIAIGESLYSIRHFREYMQKGACSIVQVDVGRIGGI 279 Query: 137 TGWVQVAGQADAASIPMSSHLFAEVSAHLLAVTPTAHWLEFLDFAGSILTRPAEIVDG-A 195 T W+++A A+A IP+ H E+ L ++E++ + + I DG A Sbjct: 280 TPWLKIAHAAEAFDIPVCPHFLMELHVSLTCAVQNGRYVEYIPQLDQLTGKHMRIEDGHA 339 Query: 196 VTARGPGLGIEWNEPAV 212 + PG+GI+W+ AV Sbjct: 340 LAPDEPGIGIDWDWDAV 356 >AGl3340 [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 378 Score = 109 bits (272), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 83/235 (35%), Positives = 117/235 (49%), Gaps = 24/235 (10%) Query: 2 VDPVAD---ERALRRSLDQGFRGIKIKGGDGNAAIDERVVKGVRALLGPDIALMIDFNQS 58 VD V+D E A RR+ +GF KIK G G D RV+ VR +GPD+ LMID N Sbjct: 142 VDRVSDNASEMAERRA--EGFHACKIKIGFG-VEEDLRVIAAVREAIGPDMRLMIDANHG 198 Query: 59 LDPAEATRRIARLAPYDLHWIEEPVPQESLSGHAKVRETSPTPIQAGENWWFPRGFAEAI 118 EA R A + + W EEPV E L +A+VR P P+ GE W G +A+ Sbjct: 199 YTVTEAITLGDRAAGFGIDWFEEPVVPEQLDAYARVRAGQPIPVAGGETWHGRYGMWQAL 258 Query: 119 AAGASDFIMPDVMKVGGVTGWVQVAGQADAASIPMSSHLFA---EVSAHL---------- 165 +AGA D + PD+ GG + ++A A + + H++ +++A L Sbjct: 259 SAGAVDILQPDLCGCGGFSEIQKIATLATLHGVRIVPHVWGTGVQIAAALQFMAAMTPDP 318 Query: 166 LAVTPTAHWLEF----LDFAGSILTRPAEIVDGAVTA-RGPGLGIEWNEPAVAKY 215 + V P +EF F ++L P E V+G VT GPGLGIE N A+ ++ Sbjct: 319 VRVNPIEPIMEFDRTHNPFRQAVLREPLEAVNGVVTIPDGPGLGIEINRDALTEF 373 >STM3697 [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Sty Salmonella typhimurium LT2 Length = 398 Score = 109 bits (272), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 67/199 (33%), Positives = 98/199 (49%), Gaps = 1/199 (0%) Query: 14 SLDQGFRGIKIKGGDGNAAIDERVVKGVRALLGPDIALMIDFNQSLDPAEATRRIARLAP 73 S + G GIK+K G N A D R + VR LG + LM+D NQ D A R ++ Sbjct: 186 SRENGIGGIKLKVGQPNCAEDIRRLTAVREALGDEFPLMVDANQQWDRETAIRMGRKMEQ 245 Query: 74 YDLHWIEEPVPQESLSGHAKVRETSPTPIQAGENWWFPRGFAEAIAAGASDFIMPDVMKV 133 ++L WIEEP+ + GHA++ TPI GE R + I ASDF+ PD +V Sbjct: 246 FNLIWIEEPLDAYDIEGHAQLAAALDTPIATGEMLTSFREHEQLILGNASDFVQPDAPRV 305 Query: 134 GGVTGWVQVAGQADAASIPMSSHLFAEVSAHLLAVTPTAHWLEFLDFAGSILTRPAEIVD 193 GG++ ++++ A ++ H EV HL A P WLE ++ + E+ D Sbjct: 306 GGISPFLKIMDLAAKHGRKLAPHFAMEVHLHLSAAYPLEPWLEHFEWLNPLFNEQLELRD 365 Query: 194 GAV-TARGPGLGIEWNEPA 211 G + + GLG +E A Sbjct: 366 GRMWISDRHGLGFTLSEQA 384