BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0051.0014.p (394 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr0089 Non COG 381 e-105 SMc00516 [R] COG3552 Protein containing von Willebrand factor ty... 374 e-103 RSc1465 [R] COG3552 Protein containing von Willebrand factor typ... 254 3e-67 mlr1707 Non COG 123 8e-28 MT0384 [S] COG3427 Uncharacterized conserved protein MtC Mycobac... 90 1e-17 >mlr0089 Non COG Length = 421 Score = 381 bits (978), Expect = e-105, Method: Compositional matrix adjust. Identities = 200/384 (52%), Positives = 266/384 (69%), Gaps = 12/384 (3%) Query: 7 APPTGHMADNVIGFARALRAAGLPVGPGSVIDALDALQLIEVGHRGDFYATLEAIFVKRH 66 A G +ADN++ FAR LR AG+ VGP SV DA++A+ +G R DFY TL A+ V RH Sbjct: 16 ATADGRIADNIVYFARTLRKAGMRVGPASVKDAIEAVLAAGIGSRDDFYWTLHAVLVSRH 75 Query: 67 EHALIFRQAFELFFRAAEEWKSMLD--SVPLPD-HARKKPPPASRRVQEAMAQPARSEER 123 E +F +AF LF+++ E + +L S PD ++KP A RV +AM + + + Sbjct: 76 EDHPVFDEAFRLFWKSRELIEKLLAMFSPVAPDVREKQKPRAAENRVSQAMFEGHQKNQP 135 Query: 124 PQAQ---EQELKLSVSDKEVLQKKDFAQMTAAEIAEVTREIAK------MXVTRRYQPDA 174 PQ E + + + S EVL+ KDFAQM AEIA+ + IA+ M TRR++ DA Sbjct: 136 PQEVPEIEVDARFTFSGNEVLRGKDFAQMNVAEIADAKKAIAELRLPFDMVRTRRFKADA 195 Query: 175 RGLRLDMRRTVRNSLRTGGEIIDIRKLGRIEKPAPIVALLDISGSMSEYTRLFLHFLHAI 234 G R+D R +R++ RTGGE+I + E P+V L DISGSMS+YTR+FLHFLHA+ Sbjct: 196 HGRRIDPRAMMRSAARTGGELILPKFRSAREVHPPLVVLADISGSMSQYTRIFLHFLHAL 255 Query: 235 TDARKRVSVFLFGTRLTNVTRALRARDPDEALASCSSSVEDWAGGTRIATSLHSFNQLWA 294 T+ R+RV F+FGTRLTN+TR +R RDPD ALA CS++V+DW+GGTRI +L FN W+ Sbjct: 256 TEKRRRVHTFVFGTRLTNLTRQMRHRDPDAALADCSAAVKDWSGGTRIGDTLAEFNLAWS 315 Query: 295 RRVLGQGAIVLLISDGLEREADAKLAFEMDRLHRSCRRLIWLNPLLRYSGFEAKAQGIKM 354 RRVLGQGA+VLLI+DGLER+ A L+ EM+RLH+SCRRLIWLNPLLR+ GF+A+A+G+K Sbjct: 316 RRVLGQGAVVLLITDGLERDDVAGLSQEMERLHKSCRRLIWLNPLLRFDGFQARARGVKA 375 Query: 355 MLPHVDEFRPVHNLTSIKGLIGAL 378 MLPHVDEFR VHNL ++ L +L Sbjct: 376 MLPHVDEFRSVHNLDALADLCASL 399 >SMc00516 [R] COG3552 Protein containing von Willebrand factor type A (vWA) domain Sme Sinorhizobium meliloti Length = 420 Score = 374 bits (959), Expect = e-103, Method: Compositional matrix adjust. Identities = 197/387 (50%), Positives = 274/387 (70%), Gaps = 21/387 (5%) Query: 11 GHMADNVIGFARALRAAGLPVGPGSVIDALDALQLIEVGHRGDFYATLEAIFVKRHEHAL 70 G +ADN++ FARALR AGL +GP ++ DA+ A++LI +G RG+FYA L+ IFVKRHE Sbjct: 10 GRLADNIVFFARALRRAGLRIGPAAIADAIGAVKLIGIGSRGEFYAALQCIFVKRHEDQA 69 Query: 71 IFRQAFELFFRAAEEWKSM---LDSVPLPDHAR-KKPPPASRRVQEAMAQPARSEERP-Q 125 +F +AF LF+R+ + M + + +P ++ RV++A+ ++P + Sbjct: 70 VFDEAFRLFWRSPDLVNKMIALMSPIAMPRSGEDRRRRAGEERVRDALLAGRDGAQQPSE 129 Query: 126 AQEQEL--KLSVSDKEVLQKKDFAQMTAAEIAEVTREIAKMXV------TRRYQPDARGL 177 A E E+ + +VS +E+ +K DF QMT AEIAE + ++ + + TRRY+ R + Sbjct: 130 APEVEVDARYTVSGRELFRKADFGQMTTAEIAEARKALSAILLPLDRVRTRRYRRSHRPV 189 Query: 178 RLDMRRTVRNSLRTGGEIIDIRKLGRIEKP----APIVALLDISGSMSEYTRLFLHFLHA 233 R+D R T+R+++R GG+ I L R +P P+V L DISGSMS+YTR+FLHFLHA Sbjct: 190 RIDPRSTMRDAMRFGGDFI----LPRFREPRLVHPPLVVLADISGSMSKYTRIFLHFLHA 245 Query: 234 ITDARKRVSVFLFGTRLTNVTRALRARDPDEALASCSSSVEDWAGGTRIATSLHSFNQLW 293 +T+ R RV FLFGTRLTNVTR +R RDPDEAL C ++V+DW+GGTRI +LH FN+ W Sbjct: 246 LTEQRHRVHTFLFGTRLTNVTRQMRNRDPDEALDDCIAAVKDWSGGTRIGETLHDFNRRW 305 Query: 294 ARRVLGQGAIVLLISDGLEREADAKLAFEMDRLHRSCRRLIWLNPLLRYSGFEAKAQGIK 353 +RRVLGQGA+VLL++DGLER+ A+L E+DRLHRSCRRL+WLNPLLR+ GFEA+A+G++ Sbjct: 306 SRRVLGQGAVVLLMTDGLERDDTAELETEIDRLHRSCRRLVWLNPLLRFDGFEARARGVR 365 Query: 354 MMLPHVDEFRPVHNLTSIKGLIGALSS 380 MLPHVDEFRP+HNL S+ L+ +LS Sbjct: 366 AMLPHVDEFRPIHNLESVADLVKSLSG 392 >RSc1465 [R] COG3552 Protein containing von Willebrand factor type A (vWA) domain Rso Ralstonia solanacearum Length = 410 Score = 254 bits (649), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 153/380 (40%), Positives = 220/380 (57%), Gaps = 15/380 (3%) Query: 7 APPTGHMADNVIGFARALRAAGLPVGPGSVIDALDALQLIEVGHRGDFYATLEAIFVKRH 66 +PP +A NV F R LR AG+P+ P +DA++AL I++G R D A L A+ V Sbjct: 8 SPPM--LARNVTHFVRLLRGAGMPLAPSRAVDAIEALGHIDIGRRDDVRAALAALLVAHP 65 Query: 67 EHALIFRQAFELFFRAAEEWKSMLDSVPLPDHARKKPPPASRRVQEAM-AQPARSEERPQ 125 + ++F AF LF+R +W+ L ++ LP P S R+ +A+ +PA Sbjct: 66 DERILFDAAFNLFWRD-PDWEGKLRALLLPRVRGGAPVQRSNRLADALRTRPAAGLPPGP 124 Query: 126 AQEQE-----LKLSVSDKEVLQKKDFAQMTAAEIAEVTREIAKMXV------TRRYQPDA 174 A E E + S E L+ +DF + A E + I + V TRR + + Sbjct: 125 APEGERHDIAAPFAFSAHEALRTRDFDTLDADEWRMLQHMIRRRRVHLAQERTRRLKAAS 184 Query: 175 RGLRLDMRRTVRNSLRTGGEIIDIRKLGRIEKPAPIVALLDISGSMSEYTRLFLHFLHAI 234 RG D+R T R ++R GGE + +++ P+V LLDISGSMS Y+R L++ HA+ Sbjct: 185 RGRHPDLRATARQAVRAGGEWTAWKYRQPVDRTPPLVLLLDISGSMSRYSRAVLYYCHAL 244 Query: 235 TDARKRVSVFLFGTRLTNVTRALRARDPDEALASCSSSVEDWAGGTRIATSLHSFNQLWA 294 +R+R+ FLFGTRLT+V+R LR RDPD A+ + + V DW+GGTRI +L FN+ WA Sbjct: 245 AQSRERIQAFLFGTRLTSVSRQLRERDPDVAVQAIAQQVPDWSGGTRIGAALAEFNRRWA 304 Query: 295 RRVLGQGAIVLLISDGLEREADAKLAFEMDRLHRSCRRLIWLNPLLRYSGFEAKAQGIKM 354 RR L A VLL++DGL+ E L EM RL R R++WLNPLLR++GFE +A+G++ Sbjct: 305 RRTLSGRATVLLVTDGLDHEHIDLLDAEMARLARFAHRIVWLNPLLRFAGFEPRARGVRA 364 Query: 355 MLPHVDEFRPVHNLTSIKGL 374 +LPHVD P H+ S+ L Sbjct: 365 ILPHVDTMVPAHHFDSLAAL 384 >mlr1707 Non COG Length = 331 Score = 123 bits (308), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 88/269 (32%), Positives = 136/269 (50%), Gaps = 6/269 (2%) Query: 119 RSEERPQAQEQELKLSVSDKEVLQKKDFAQMTAAEIAEVTREIAKMXVTRR----YQPDA 174 R EE +++E S E L +DF Q +A R+++ RR + + Sbjct: 55 REEEDQTVRKEEGGELSSALEQLSTRDF-QRDDDRLAAFRRKLSSALPARRSFRTVRTPS 113 Query: 175 RGLRLDMRRTVRNSLRTGGEIIDIRKLGRIEKPAPIVALLDISGSMSEYTRLFLHFLHAI 234 RG +LD+RR++R + G++ R P ++ L+D+SGSM +T +L HA Sbjct: 114 RG-KLDLRRSLREIVSADGDVPSPLLRRRQTVPRKLLLLIDVSGSMKLHTADYLKLAHAA 172 Query: 235 TDARKRVSVFLFGTRLTNVTRALRARDPDEALASCSSSVEDWAGGTRIATSLHSFNQLWA 294 R +F FGTRLT +T ALR RD ++ALA ++ V+DW GGTR+ +L +F + Sbjct: 173 VQGADRAEIFTFGTRLTRITSALRIRDRNQALARAAAQVDDWDGGTRMGPTLLAFLSVPR 232 Query: 295 RRVLGQGAIVLLISDGLEREADAKLAFEMDRLHRSCRRLIWLNPLLRYSGFEAKAQGIKM 354 +GA V+++SD LER A+L M RL RL PL F ++ Sbjct: 233 FSSFARGAAVVILSDALERGDHAELETAMRRLSARAFRLSLATPLAGDPRFRPATAALRA 292 Query: 355 MLPHVDEFRPVHNLTSIKGLIGALSSPPP 383 +LP +D+ +LTS+ I +L+ P P Sbjct: 293 ILPDLDDLIDGSSLTSLTDFILSLARPAP 321 >MT0384 [S] COG3427 Uncharacterized conserved protein MtC Mycobacterium tuberculosis CDC1551 [R] COG3552 Protein containing von Willebrand factor type A (vWA) domain MtC Mycobacterium tuberculosis CDC1551 Length = 403 Score = 89.7 bits (221), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 65/213 (30%), Positives = 106/213 (49%), Gaps = 3/213 (1%) Query: 169 RYQPDARGLRLDMRRTVRNSLRTGGEIIDIRKLGRIEKPAPIVALLDISGSMSEYTRLFL 228 R++ G R+D+R T+ S TG E + + ++ +P ++ L D+S SM Y ++L Sbjct: 189 RFESSPHGKRIDLRATMNASRSTGWESVLLARIRPRRRPRRVLLLCDVSRSMQPYAAIYL 248 Query: 229 HFLHA--ITDARKRVSVFLFGTRLTNVTRALRARDPDEALASCSSSVEDWAGGTRIATSL 286 + A + A VF F T LT +T L R + AL ++ V D GGT I S+ Sbjct: 249 RLMRAAVLRRAGGHPEVFAFSTSLTRLTSVLSHRSAEMALHRANARVTDRYGGTFIGRSV 308 Query: 287 HSFNQLWARRVLGQGAIVLLISDGLEREADAKLAFEMDRLHRSCRRLIWLNPLLRYSGFE 346 + L +GA+V++ SDG + + L + R+ R L+WLNP + F+ Sbjct: 309 AALLAPPHGNAL-RGAVVIIASDGWDSDPPDVLVHALTRVRRRAELLVWLNPRAAHPEFQ 367 Query: 347 AKAQGIKMMLPHVDEFRPVHNLTSIKGLIGALS 379 +A + LP+ D F P H+L + L+ AL+ Sbjct: 368 PRAGSMAAALPYCDLFLPAHSLAGLHQLLLALA 400