BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0050.0049.p (186 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr4588 [T] COG2114 Adenylate cyclase, family 3 (some proteins c... 130 2e-30 all1904_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins... 115 4e-26 SMa1046 [T] COG2114 Adenylate cyclase, family 3 (some proteins c... 114 9e-26 alr2266_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins... 114 1e-25 all1118_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins... 114 1e-25 >mlr4588 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Mlo Mesorhizobium loti Length = 458 Score = 130 bits (326), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 68/181 (37%), Positives = 103/181 (56%), Gaps = 1/181 (0%) Query: 1 LFADVVGFTALTSEKTPDEVIGFLRELLAMLGEAVFAHGGSIDKFLGDGLMAVFGPPLAS 60 LFAD+VGFT + + + V LR+ + + VF H G++D ++GD +MA FG P AS Sbjct: 264 LFADIVGFTHYSEDHPAEAVFELLRQFHRRMEQVVFDHHGTVDNYIGDCIMATFGVPQAS 323 Query: 61 DRDATNAARCAIRMHDCLAHWNVRHANNPSKLIRIAVGIHWGEVVQGDIGTDKRLEFTVV 120 DAT A +CA M L WNV+ + + + +G +G VV G +G+++ L F VV Sbjct: 324 HDDATRAIQCAEAMVAALEDWNVQRVSRGYPPLDVRIGAQYGAVVIGAVGSERNLSFAVV 383 Query: 121 GDTVNIASRVEAYCRTLNATVLVTGDFIQSLIAEGSVDVANAFTSEGKHLLRGCRKPLHL 180 GDTVN+ASR+++ CR L A + I++ AE NA G +RG +P+H+ Sbjct: 384 GDTVNVASRLQSLCRELQANICFGSRLIEAAKAESPTTRLNA-RDHGPVSIRGRDEPVHV 442 Query: 181 Y 181 + Sbjct: 443 W 443 >all1904_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Nos Nostoc sp. PCC 7120 Length = 296 Score = 115 bits (289), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 57/148 (38%), Positives = 89/148 (60%), Gaps = 4/148 (2%) Query: 1 LFADVVGFTALTSEKTPDEVIGFLRELLAMLGEAVFAHGGSIDKFLGDGLMAVFGPPLAS 60 LF+D+ G+T LT +EV+ L E + EAVF H G++DK++GD +MAVFG PL Sbjct: 39 LFSDIRGYTTLTENLEAEEVVSMLNEYFESMVEAVFKHKGTLDKYIGDAIMAVFGSPLPL 98 Query: 61 DRDATNAARCAIRMHDCLAHWNVRH--ANNPSKLIRIAVGIHWGEVVQGDIGTDKRLEFT 118 + A A + +I M L +N + AN P I I +GI+ V+ G+IG+ KR+EFT Sbjct: 99 EEHAWMAVKTSIEMRHRLQEFNQKRYAANKPR--INIGIGINSDTVISGNIGSSKRMEFT 156 Query: 119 VVGDTVNIASRVEAYCRTLNATVLVTGD 146 +GD VN+ SR+E+ + ++++ + Sbjct: 157 AIGDGVNLGSRLESVSKQYGCDIILSDN 184 >SMa1046 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Sme Sinorhizobium meliloti Length = 355 Score = 114 bits (286), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 63/183 (34%), Positives = 103/183 (56%), Gaps = 3/183 (1%) Query: 1 LFADVVGFTALTSEKTPDEVIGFLRELLAMLGEAVFAHGGSIDKFLGDGLMAVFGPPLAS 60 +F D+ FT+ T E+ L E ++ + +F HGG++DKF+GDG+MAVFG P + Sbjct: 136 MFVDLRDFTSFAETATARELAFVLAEYRQLVSQTIFDHGGTVDKFIGDGVMAVFGQPRPT 195 Query: 61 DRDATNAARCAIRMHDCLAHWNVRHANNPSKLIRIAVGIHWGEVVQGDIGTDKRLEFTVV 120 D DA A CA+ + D L+ W + A+G+H+G VV G + + EFTV+ Sbjct: 196 DDDADRALACALDLVDTLSDWRSHGVRIGYPALDAAIGLHYGTVVGGVLDSGCHSEFTVI 255 Query: 121 GDTVNIASRVEAYCRTLNATVLVTGDFIQSLIAEGSVDVANAFTSEGKHLLRGCRKPLHL 180 GD VN+A R+E ++L+A+++++ + + L + V A A+ S L G R P+ + Sbjct: 256 GDAVNVAQRLETLAKSLDASLVISSNLVARL--QSPVPPA-AWMSVTSAALPGRRLPIDV 312 Query: 181 YSL 183 + L Sbjct: 313 WYL 315 >alr2266_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Nos Nostoc sp. PCC 7120 Length = 296 Score = 114 bits (286), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 57/145 (39%), Positives = 88/145 (60%), Gaps = 1/145 (0%) Query: 1 LFADVVGFTALTSEKTPDEVIGFLRELLAMLGEAVFAHGGSIDKFLGDGLMAVFGPPLA- 59 LF+D+ G+T LT EV+ L + + EAVF + G++DKF+GD LMAVFG PL Sbjct: 40 LFSDIRGYTTLTENLGAAEVVSLLNQYFETMVEAVFNYEGTLDKFIGDALMAVFGAPLPL 99 Query: 60 SDRDATNAARCAIRMHDCLAHWNVRHANNPSKLIRIAVGIHWGEVVQGDIGTDKRLEFTV 119 ++ A A + A+ M L +N R I+I +GI GEVV G+IG+ KR+++TV Sbjct: 100 TENHAWQAVQSALDMRQRLKEFNQRRIIQAQPQIKIGIGISSGEVVSGNIGSHKRMDYTV 159 Query: 120 VGDTVNIASRVEAYCRTLNATVLVT 144 +GD VN++SR+E + ++++ Sbjct: 160 IGDGVNLSSRLETVTKEYGCDIILS 184 >all1118_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Nos Nostoc sp. PCC 7120 Length = 322 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 59/184 (32%), Positives = 108/184 (58%), Gaps = 10/184 (5%) Query: 1 LFADVVGFTALTSEKTPDEVIGFLRELLAMLGEAVFAHGGSIDKFLGDGLMAVFGPPLAS 60 LF+D+ GF+A++ + +P++V+ L L ++ + + + G+I++F+GDG+ +FG P+ Sbjct: 32 LFSDLRGFSAMSEQLSPEQVVQILNLYLGVMTDVINQYKGTINEFIGDGIFIMFGAPICR 91 Query: 61 DRDATNAARCAIRMHDCLAHWNVR-HANNPSKLIRIAVGIHWGEVVQGDIGTDKRLEFTV 119 D+ A CAI M + N + H N +L + +GI+ GEVV G+IG+ KR ++TV Sbjct: 92 PDDSQRAIACAIAMQRAMQQVNAKTHQMNLPQL-EMGIGINTGEVVAGNIGSQKRAQYTV 150 Query: 120 VGDTVNIASRVEAYCRTLNATVLVTGDFIQSLIAEGSVDVANAFTSEGKHLLRGCRKPLH 179 +G VN+A+R+E Y T+ +L++ + Q A + +A E K G ++P+ Sbjct: 151 IGSHVNLAARIETY--TVGGQILISENTRQD--ANTDLQIAGQMQIEPK----GIKEPIT 202 Query: 180 LYSL 183 +Y + Sbjct: 203 IYEI 206