BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0050.0048.p (106 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO0355 [P] COG2076 Membrane transporters of cations and cationi... 116 1e-26 STM4338 [P] COG2076 Membrane transporters of cations and cationi... 111 5e-25 sugE [P] COG2076 Membrane transporters of cations and cationic d... 108 3e-24 ZsugE [P] COG2076 Membrane transporters of cations and cationic ... 108 3e-24 ECs5129 [P] COG2076 Membrane transporters of cations and cationi... 108 3e-24 >YPO0355 [P] COG2076 Membrane transporters of cations and cationic drugs Ype Yersinia pestis Length = 104 Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 62/104 (59%), Positives = 81/104 (77%) Query: 1 MTWIILVSAGVLEIGFALSMKWSVGFTRLTPSLFAAAAGLSSVFLLSLALRALPVGTGYA 60 M WIILV AG+LE+ +A+ +K+S GF+RLTPS+ A +SVFLL+ A+++LP GT YA Sbjct: 1 MAWIILVIAGLLEVIWAIGLKYSHGFSRLTPSIITLVAMAASVFLLAYAMKSLPAGTAYA 60 Query: 61 VWTGIGAAGTAIFGMALLGDSASPARVLCIVFIVGGVIGLKLVS 104 VWTGIGA GTAI G+ LLG+SAS AR+L + I+ G+IGLKL S Sbjct: 61 VWTGIGAVGTAILGIVLLGESASLARILSLGLILAGIIGLKLAS 104 >STM4338 [P] COG2076 Membrane transporters of cations and cationic drugs Sty Salmonella typhimurium LT2 Length = 105 Score = 111 bits (277), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 59/102 (57%), Positives = 80/102 (78%) Query: 1 MTWIILVSAGVLEIGFALSMKWSVGFTRLTPSLFAAAAGLSSVFLLSLALRALPVGTGYA 60 M+WIIL+ AG+LE+ +A+ +K++ GF+RLTPS+ A + S+ LLS A++ LPVGT YA Sbjct: 1 MSWIILLIAGLLEVVWAVGLKYTHGFSRLTPSIITITAMVISMALLSWAMKTLPVGTAYA 60 Query: 61 VWTGIGAAGTAIFGMALLGDSASPARVLCIVFIVGGVIGLKL 102 +WTGIGA G AI G+ LLG+SASPAR+L + IV G+IGLKL Sbjct: 61 IWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKL 102 >sugE [P] COG2076 Membrane transporters of cations and cationic drugs Eco Escherichia coli K12 Length = 155 Score = 108 bits (270), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 57/102 (55%), Positives = 79/102 (77%) Query: 1 MTWIILVSAGVLEIGFALSMKWSVGFTRLTPSLFAAAAGLSSVFLLSLALRALPVGTGYA 60 M+WIILV AG+LE+ +A+ +K++ GF+RLTPS+ A + S+ LL+ A+++LPVGT YA Sbjct: 51 MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMALLAWAMKSLPVGTAYA 110 Query: 61 VWTGIGAAGTAIFGMALLGDSASPARVLCIVFIVGGVIGLKL 102 VWTGIGA G AI G+ LLG+SA+P R+ + IV G+IGLKL Sbjct: 111 VWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL 152 >ZsugE [P] COG2076 Membrane transporters of cations and cationic drugs EcZ Escherichia coli O157:H7 EDL933 Length = 155 Score = 108 bits (270), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 57/102 (55%), Positives = 79/102 (77%) Query: 1 MTWIILVSAGVLEIGFALSMKWSVGFTRLTPSLFAAAAGLSSVFLLSLALRALPVGTGYA 60 M+WIILV AG+LE+ +A+ +K++ GF+RLTPS+ A + S+ LL+ A+++LPVGT YA Sbjct: 51 MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMALLAWAMKSLPVGTAYA 110 Query: 61 VWTGIGAAGTAIFGMALLGDSASPARVLCIVFIVGGVIGLKL 102 VWTGIGA G AI G+ LLG+SA+P R+ + IV G+IGLKL Sbjct: 111 VWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL 152 >ECs5129 [P] COG2076 Membrane transporters of cations and cationic drugs Ecs Escherichia coli O157:H7 Length = 155 Score = 108 bits (270), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 57/102 (55%), Positives = 79/102 (77%) Query: 1 MTWIILVSAGVLEIGFALSMKWSVGFTRLTPSLFAAAAGLSSVFLLSLALRALPVGTGYA 60 M+WIILV AG+LE+ +A+ +K++ GF+RLTPS+ A + S+ LL+ A+++LPVGT YA Sbjct: 51 MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMALLAWAMKSLPVGTAYA 110 Query: 61 VWTGIGAAGTAIFGMALLGDSASPARVLCIVFIVGGVIGLKL 102 VWTGIGA G AI G+ LLG+SA+P R+ + IV G+IGLKL Sbjct: 111 VWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL 152