BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0050.0025.p (229 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO3263 [GEPR] COG0477 Permeases of the major facilitator superf... 153 3e-37 SMa1959 [GEPR] COG0477 Permeases of the major facilitator superf... 144 2e-34 b2681m [GEPR] COG0477 Permeases of the major facilitator superfa... 136 4e-32 ECs3543 [GEPR] COG0477 Permeases of the major facilitator superf... 135 8e-32 Z3982 [GEPR] COG0477 Permeases of the major facilitator superfam... 134 1e-31 >YPO3263 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 399 Score = 153 bits (386), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 97/224 (43%), Positives = 135/224 (60%), Gaps = 3/224 (1%) Query: 1 VLAALLARALPRHAPQPMAGSSYAKLLRSTVALFVEEQVLRERAVFALLIFASFSVFWSS 60 ++A +L R LPR+ G +Y +LL S ALF+ VLR RA+ L FA+FSV W+S Sbjct: 177 IMALVLWRCLPRYKQH--TGLNYGQLLGSIFALFIHTPVLRTRALLGALSFANFSVLWTS 234 Query: 61 VVLPLAAPPLSLSHTTIGMLGIAGLAGALAARNSGQLADRGWGQRTTGLSLLLMLAGWVP 120 + LAAPP S TIG+ G+ G AGAL A +GQLAD+G + TT L+L+L W+P Sbjct: 235 MAFLLAAPPFGYSEATIGLFGLVGAAGALMATKAGQLADKGKARVTTSAGLVLLLLSWLP 294 Query: 121 IACLNTSPWLVVAGVLMIDFAVQAIHVTNQSLIVAARPDAASRLVGGYMVFYSIGTGFGA 180 IA S ++ G++++D AVQA+HVTNQS++ P+A +RL GYM Y IG G+ Sbjct: 295 IAFGQHSIIALIIGIIVLDLAVQAVHVTNQSVMYRMMPEARNRLTAGYMTSYFIGGALGS 354 Query: 181 ISSTMAYAAAGWPGVCVLGAAISACALLYWVI-VVSRTPAAQSV 223 + S AY AGW GV G + ++ W++ S PA Q+V Sbjct: 355 LISAAAYQHAGWYGVSTAGLVLCLLNIVTWLVGKRSDQPANQTV 398 >SMa1959 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 469 Score = 144 bits (363), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 107/217 (49%), Positives = 142/217 (65%), Gaps = 5/217 (2%) Query: 2 LAALLARALPRHAPQPMAGS--SYAKLLRSTVALFVEEQVLRERAVFALLIFASFSVFWS 59 + A+LAR +P QP +G SY KL+ S LF++E VLR RA+ A LIFA + + Sbjct: 253 ITAILARVVP---AQPKSGPAVSYPKLIGSLFTLFLQEPVLRVRAILAFLIFADVTTLLT 309 Query: 60 SVVLPLAAPPLSLSHTTIGMLGIAGLAGALAARNSGQLADRGWGQRTTGLSLLLMLAGWV 119 +VLPL+APP SLSH IG+ G+AG AGAL A +G+ D G+GQR TG++L LML W+ Sbjct: 310 PLVLPLSAPPYSLSHAAIGLFGLAGAAGALGASRAGRWTDEGFGQRVTGVALTLMLCSWI 369 Query: 120 PIACLNTSPWLVVAGVLMIDFAVQAIHVTNQSLIVAARPDAASRLVGGYMVFYSIGTGFG 179 I L S +V GVL++DF +QA+HV +Q LI RP+A SRL YMVFYS G+ G Sbjct: 370 LIGLLPYSILFLVTGVLLLDFGLQAVHVASQGLIYRVRPEAQSRLTAAYMVFYSTGSALG 429 Query: 180 AISSTMAYAAAGWPGVCVLGAAISACALLYWVIVVSR 216 + ST+ YA W GV +LGA I+A ALL+W I + + Sbjct: 430 SSISTLVYARWAWTGVSMLGAGIAAAALLFWAITLPK 466 >b2681m [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 392 Score = 136 bits (343), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 95/223 (42%), Positives = 134/223 (60%), Gaps = 2/223 (0%) Query: 1 VLAALLARALPRHAPQPMAGS--SYAKLLRSTVALFVEEQVLRERAVFALLIFASFSVFW 58 VL AL+A AL R PQ + + +Y +LL S ++F+ +++LR RA+ L FA+FS+ W Sbjct: 170 VLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFISDKILRTRALLGCLTFANFSILW 229 Query: 59 SSVVLPLAAPPLSLSHTTIGMLGIAGLAGALAARNSGQLADRGWGQRTTGLSLLLMLAGW 118 +S+ LAAPP + S IG+ G+AG AGAL AR +G AD+G TT LLL+L W Sbjct: 230 TSMAFLLAAPPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKSHHTTTFGLLLLLLSW 289 Query: 119 VPIACLNTSPWLVVAGVLMIDFAVQAIHVTNQSLIVAARPDAASRLVGGYMVFYSIGTGF 178 + I +TS ++ G+L++D VQ +H+TNQ++I PDA +RL GYM Y IG Sbjct: 290 LAIWFGHTSVLALIIGILVLDLTVQGVHITNQTVIYRIHPDARNRLTAGYMTSYFIGGAA 349 Query: 179 GAISSTMAYAAAGWPGVCVLGAAISACALLYWVIVVSRTPAAQ 221 G++ S A+ GW GVC+ GA I+ LL W R AA Sbjct: 350 GSLISASAWQHGGWAGVCLAGATIALVNLLVWWRGFHRQEAAN 392 >ECs3543 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 394 Score = 135 bits (340), Expect = 8e-32, Method: Compositional matrix adjust. Identities = 95/223 (42%), Positives = 133/223 (59%), Gaps = 2/223 (0%) Query: 1 VLAALLARALPRHAPQPMAGS--SYAKLLRSTVALFVEEQVLRERAVFALLIFASFSVFW 58 VL AL+A AL R PQ + + +Y +LL S ++F+ ++LR RA+ L FA+FS+ W Sbjct: 172 VLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFISNKILRTRALLGCLTFANFSILW 231 Query: 59 SSVVLPLAAPPLSLSHTTIGMLGIAGLAGALAARNSGQLADRGWGQRTTGLSLLLMLAGW 118 +S+ LAAPP + S IG+ G+AG AGAL AR +G AD+G TT LLL+L W Sbjct: 232 TSMAFLLAAPPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKSHHTTTFGLLLLLLSW 291 Query: 119 VPIACLNTSPWLVVAGVLMIDFAVQAIHVTNQSLIVAARPDAASRLVGGYMVFYSIGTGF 178 + I +TS ++ G+L++D VQ +H+TNQ++I PDA +RL GYM Y IG Sbjct: 292 LAIWFGHTSVLALIIGILVLDLTVQGVHITNQTVIYRIHPDARNRLTAGYMTSYFIGGAA 351 Query: 179 GAISSTMAYAAAGWPGVCVLGAAISACALLYWVIVVSRTPAAQ 221 G++ S A+ GW GVC+ GA I+ LL W R AA Sbjct: 352 GSLISASAWQHGGWAGVCLAGATIALVNLLVWWRGFHRQEAAN 394 >Z3982 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 394 Score = 134 bits (338), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 95/223 (42%), Positives = 133/223 (59%), Gaps = 2/223 (0%) Query: 1 VLAALLARALPRHAPQPMAGS--SYAKLLRSTVALFVEEQVLRERAVFALLIFASFSVFW 58 VL AL+A AL R PQ + + +Y +LL S ++F+ ++LR RA+ L FA+FS+ W Sbjct: 172 VLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFISNKILRTRALLGCLTFANFSIXW 231 Query: 59 SSVVLPLAAPPLSLSHTTIGMLGIAGLAGALAARNSGQLADRGWGQRTTGLSLLLMLAGW 118 +S+ LAAPP + S IG+ G+AG AGAL AR +G AD+G TT LLL+L W Sbjct: 232 TSMAFLLAAPPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKSHHTTTFGLLLLLLSW 291 Query: 119 VPIACLNTSPWLVVAGVLMIDFAVQAIHVTNQSLIVAARPDAASRLVGGYMVFYSIGTGF 178 + I +TS ++ G+L++D VQ +H+TNQ++I PDA +RL GYM Y IG Sbjct: 292 LAIWFGHTSVLALIIGILVLDLTVQGVHITNQTVIYRIHPDARNRLTAGYMTSYFIGGAA 351 Query: 179 GAISSTMAYAAAGWPGVCVLGAAISACALLYWVIVVSRTPAAQ 221 G++ S A+ GW GVC+ GA I+ LL W R AA Sbjct: 352 GSLISASAWQHGGWAGVCLAGATIALVNLLVWWRGFHRQEAAN 394