BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0043.0023.p (317 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMB0929 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuram... 203 5e-52 NMA1124 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuram... 201 2e-51 CC1195 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneurami... 194 2e-49 mlr7746 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuram... 185 1e-46 HI0255 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneurami... 185 1e-46 >NMB0929 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase Nme Neisseria meningitidis MC58 Length = 291 Score = 203 bits (516), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 112/285 (39%), Positives = 168/285 (58%), Gaps = 3/285 (1%) Query: 23 LSGFIPDLPTPFNHQDQIDIEAFGRLCERQIAAGASALAVGETAGESSTLEPTERAQLVR 82 L G + L TP N I E L + I G + T GES+TL E ++ Sbjct: 2 LQGSLVALITPMNQDGSIHYEQLRDLIDWHIENGTDGIVAVGTTGESATLSVEEHTAVIE 61 Query: 83 -IAAHVARKRVGIIAGAGSNATDRAVAFTRAPEAAGADAIMSVVPYYNKPMPQGIAAHFR 141 + HVA KRV +IAG G+N T A+A ++A E AGAD +SVVPYYNKP +GI HF+ Sbjct: 62 AVVKHVA-KRVPVIAGTGANNTVEAIALSQAAEKAGADYTLSVVPYYNKPSQEGIYQHFK 120 Query: 142 AVAAATTLPVILHDIPARTVKGLADETLLELAHSPRFVGLRDGNSDVARLRRLRPRLPAT 201 +A AT++P+I++++P RTV + ++T+L LA P VG+++ + ++ L R P Sbjct: 121 TIAEATSIPMIIYNVPGRTVVSMTNDTILRLAEIPNIVGVKEASGNIGSNIELINRAPEG 180 Query: 202 FRMLTGDDATSLAYMAAGGDGCISSVSNIAPDLWVAVARHLREGRLYQARELHQRLVPLA 261 F +L+GDD T+L +M GG G I+ +N AP L+ + R +G + AREL+ RL+P+ Sbjct: 181 FVVLSGDDHTALPFMLCGGHGVITVAANAAPKLFADMCRAALQGDIALARELNDRLIPIY 240 Query: 262 -TLLEREHPAALKFALALLGFMQPATRLPIVQLNASAKAEVAQAM 305 T+ PAA K+A++ LG +P RLP+V L + +A+V A+ Sbjct: 241 DTMFCEPSPAAPKWAVSALGRCEPHVRLPLVPLTENGQAKVRAAL 285 >NMA1124 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase NmA Neisseria meningitidis Z2491 Length = 291 Score = 201 bits (511), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 114/285 (40%), Positives = 166/285 (58%), Gaps = 3/285 (1%) Query: 23 LSGFIPDLPTPFNHQDQIDIEAFGRLCERQIAAGASALAVGETAGESSTLEPTERAQLVR 82 L G + L TP N I E L + I G + T GES+TL E ++ Sbjct: 2 LQGSLVALITPMNQDGSIHYEQLRDLIDWHIENGTDGIVAVGTTGESATLSVEEHTAVIE 61 Query: 83 -IAAHVARKRVGIIAGAGSNATDRAVAFTRAPEAAGADAIMSVVPYYNKPMPQGIAAHFR 141 + HVA KRV +IAG G+N T A+A ++A E AGAD +SVVPYYNKP +G+ HF+ Sbjct: 62 AVVKHVA-KRVPVIAGTGANNTVEAIALSQAAEKAGADYTLSVVPYYNKPSQEGMYRHFK 120 Query: 142 AVAAATTLPVILHDIPARTVKGLADETLLELAHSPRFVGLRDGNSDVARLRRLRPRLPAT 201 AVA A +P+IL+++P RTV + +ET+L LA P VG+++ + ++ L R P Sbjct: 121 AVAEAAAIPMILYNVPGRTVVSMNNETILRLAEIPNIVGVKEASGNIGSNIELINRAPEG 180 Query: 202 FRMLTGDDATSLAYMAAGGDGCISSVSNIAPDLWVAVARHLREGRLYQARELHQRLVPLA 261 F +L+GDD T+L +M GG G I+ +N AP L+ + R +G + AREL+ RL+P+ Sbjct: 181 FVVLSGDDHTALPFMLCGGHGVITVAANAAPKLFADMCRAALQGDIALARELNDRLIPIY 240 Query: 262 -TLLEREHPAALKFALALLGFMQPATRLPIVQLNASAKAEVAQAM 305 T+ PAA K+A++ LG +P RLP+V L +A+V A+ Sbjct: 241 DTMFCEPSPAAPKWAVSALGRCEPHVRLPLVPLTEGGQAKVRAAL 285 >CC1195 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase Ccr Caulobacter vibrioides Length = 294 Score = 194 bits (493), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 110/284 (38%), Positives = 151/284 (53%), Gaps = 2/284 (0%) Query: 23 LSGFIPDLPTPFNHQDQIDIEAFGRLCERQIAAGASALAVGETAGESSTLEPTERAQLVR 82 G IP L TPF ++D +AF L ERQIA G L T GE+STL E ++V Sbjct: 6 FKGVIPALVTPFR-DGEVDEKAFVALVERQIAGGVHGLVPVGTTGETSTLSHEEHRRVVE 64 Query: 83 IAAHVARKRVGIIAGAGSNATDRAVAFTRAPEAAGADAIMSVVPYYNKPMPQGIAAHFRA 142 + RV +IAGAGSN+TD A+ R + GADA + V PYYN+P +G+ H++A Sbjct: 65 LCVKTTAGRVPVIAGAGSNSTDEAIELARHAKTVGADACLVVTPYYNRPSQEGMYQHYKA 124 Query: 143 VAAATTLPVILHDIPARTVKGLADETLLELAHSPRFVGLRDGNSDVARLRRLRPRLPATF 202 + A LP+ ++++P RT ++++TL LA P VG++D D+ R+ R + Sbjct: 125 INDAVELPIFVYNVPGRTGVDISNDTLERLAKLPNIVGIKDATGDLTRISFQRLMCGPEW 184 Query: 203 RMLTGDDATSLAYMAAGGDGCISSVSNIAPDLWVAVARHLREGRLYQARELHQRLVPL-A 261 ML+GDD T+L YMA GG G IS SN+APD A +G + RLV L Sbjct: 185 VMLSGDDPTALGYMAHGGHGVISVTSNVAPDACSAFMNACMQGEWEKGLYWQDRLVRLHK 244 Query: 262 TLLEREHPAALKFALALLGFMQPATRLPIVQLNASAKAEVAQAM 305 L PA KFA+A LG RLPI + + +AM Sbjct: 245 ALFLDSSPAPTKFAMAQLGLCTEDVRLPITACAEGVRPAILEAM 288 >mlr7746 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase Mlo Mesorhizobium loti Length = 305 Score = 185 bits (470), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 114/286 (39%), Positives = 154/286 (53%), Gaps = 4/286 (1%) Query: 23 LSGFIPDLPTPFNHQDQIDIEAFGRLCERQIAAGASALAVGETAGESSTLEPTERAQLVR 82 L G + L TPF + D +AF E Q+ G + L T GES TL E +V+ Sbjct: 14 LRGSLTALVTPFEKSGRFDEKAFRAFVEWQLGEGTTGLVPVGTTGESPTLSHDEHRHVVK 73 Query: 83 IAAHVARKRVGIIAGAGSNATDRAVAFTRAPEAAGADAIMSVVPYYNKPMPQGIAAHFRA 142 + VA R ++AGAGSN T AV + E AGADA + V PYYNKP +G+ HF A Sbjct: 74 VCIEVANGRAPVVAGAGSNNTAEAVGLVQYAEKAGADAALVVTPYYNKPTQRGLYEHFAA 133 Query: 143 VAAATTLPVILHDIPARTVKGLADETLLELAHS-PRFVGLRDGNSDVARLRRLRPRLPAT 201 VA AT LP+I+++IP R+V + ET+ LAH VG++D V R+ R Sbjct: 134 VARATKLPIIIYNIPPRSVIDMMPETMGRLAHDFKNIVGVKDATGKVERVSEQRMTCGKD 193 Query: 202 FRMLTGDDATSLAYMAAGGDGCISSVSNIAPDLWVAVARHLREGRLYQARELHQRLVPL- 260 F L+G+DA++L + A GG GCIS SN+AP L G +A EL RL+PL Sbjct: 194 FIQLSGEDASALGFNAHGGVGCISVTSNVAPRLCAEFQEATLSGDSVKALELQDRLLPLH 253 Query: 261 -ATLLEREHPAALKFALALLGFMQPATRLPIVQLNASAKAEVAQAM 305 A LE A K+AL+ LG ++ R P+V + S A++ AM Sbjct: 254 KAIFLEPGVSGA-KYALSKLGKVENVLRSPLVTVEESTAAKIDAAM 298 >HI0255 [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase Hin Haemophilus influenzae Length = 298 Score = 185 bits (469), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 103/285 (36%), Positives = 158/285 (55%), Gaps = 2/285 (0%) Query: 23 LSGFIPDLPTPFNHQDQIDIEAFGRLCERQIAAGASALAVGETAGESSTLEPTERAQLVR 82 SG I L TP NH ++D +L E I AG++AL T GES+TL E +++ Sbjct: 8 FSGSIVALVTPMNHYGEVDFSCLEKLVEHHIEAGSNALVSVGTTGESATLSIEENVKVIE 67 Query: 83 IAAHVARKRVGIIAGAGSNATDRAVAFTRAPEAAGADAIMSVVPYYNKPMPQGIAAHFRA 142 A+ R+ IIAGAG+NAT A+ T+ +G +SVVPYYNKP +G+ HF+A Sbjct: 68 KTVEFAKGRIPIIAGAGANATSEAITMTKLLRDSGVAGCLSVVPYYNKPTQEGMYQHFKA 127 Query: 143 VAAATTLPVILHDIPARTVKGLADETLLELAHSPRFVGLRDGNSDVARLRRLRPRLPATF 202 +A T LP IL+++P+RT + ET+ LA VG+++ DV+R+ +++ F Sbjct: 128 IAECTDLPQILYNVPSRTGSDMKPETVARLAEIENIVGIKEATRDVSRIVKIKQLAGKNF 187 Query: 203 RMLTGDDATSLAYMAAGGDGCISSVSNIAPDLWVAVARHLREGRLYQARELHQRLVPL-A 261 +L+GDDAT L + G +G IS +NIA + R+ G +A E++ RL+ L Sbjct: 188 IVLSGDDATGLEAIKLGAEGVISVTNNIAAKDMADMCRYALAGDFDKAEEINARLMRLHH 247 Query: 262 TLLEREHPAALKFALALLGFMQ-PATRLPIVQLNASAKAEVAQAM 305 L +P +K+A LG ++ P RLP+ L+ + +V A+ Sbjct: 248 DLFIESNPIPVKWAAYRLGLIKSPHLRLPLTTLSEEIQPKVGDAL 292