BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0043.0008.p (379 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1535 [I] COG1960 Acyl-CoA dehydrogenases Pae Pseudomonas aerug... 410 e-114 Rv0975c [I] COG1960 Acyl-CoA dehydrogenases Mtu Mycobacterium tu... 294 2e-79 MT1003 [I] COG1960 Acyl-CoA dehydrogenases MtC Mycobacterium tub... 294 2e-79 PA4435 [I] COG1960 Acyl-CoA dehydrogenases Pae Pseudomonas aerug... 255 1e-67 BH3798 [I] COG1960 Acyl-CoA dehydrogenases Bha Bacillus halodurans 249 6e-66 >PA1535 [I] COG1960 Acyl-CoA dehydrogenases Pae Pseudomonas aeruginosa Length = 382 Score = 410 bits (1054), Expect = e-114, Method: Compositional matrix adjust. Identities = 204/377 (54%), Positives = 267/377 (70%), Gaps = 3/377 (0%) Query: 5 FYTGEHEAFREVMRRFVAREIEPYAHQWDEDGEFPRELYAKASAIGLLGLGFPEEYGG-I 63 ++ H+ R+ +RRFV RE+ PY +W+E EFPRELY KA A G+LG+G+PE YGG Sbjct: 7 YFDESHQLIRDSVRRFVEREVLPYIDEWEEAEEFPRELYLKAGAAGILGIGYPEAYGGSC 66 Query: 64 AADQFMKIVASQELAQAGAGGVSSSLMSHTIGSPPIARAARPEVKARVLPEVLAGKKISA 123 D F K+ AS+EL + G+GG+ + L S IG PP+ + ARPEV+ RV+P VL G+KI A Sbjct: 67 EGDLFAKVAASEELMRCGSGGLVAGLGSLDIGLPPVVKWARPEVRERVVPAVLRGEKIMA 126 Query: 124 LAITEPSGGSDVANLRTRARREGDHYVVSGEKTFITSGMRADYLTVAVRTGGEGSGGVSL 183 LA+TEPSGGSDVANL+TRA R+GDHY VSG KTFITSG+RADY TVAVRTGGEG G+SL Sbjct: 127 LAVTEPSGGSDVANLKTRAVRDGDHYRVSGSKTFITSGVRADYYTVAVRTGGEGFAGISL 186 Query: 184 LLIEGNTPGLSR-TKLKKMGWWASDTATLHFDECRVPVENLIGEEGQGFKIIMQNFNSER 242 LL+E T G S KLKKMGWWASDTA L FD+CRVP ENLIG E GF IM NF SER Sbjct: 187 LLVEKGTAGFSVGRKLKKMGWWASDTAELFFDDCRVPAENLIGVENAGFACIMANFQSER 246 Query: 243 MGMAASCTAYARVCLDEAVAYAKERKTFGKPIAQHQVIRHKIVDMAQKVAASQAMLEMLA 302 + +A A++ L+E++ +A+ER+ FGKPI + QV+RH++ +MA ++ S+ A Sbjct: 247 LALAVMANMTAQLALEESLRWAREREAFGKPIGKFQVLRHRLAEMATQLEVSREFTYRQA 306 Query: 303 WRLGHGESPVAEICMMKNQATQTMAHCASEAVQIFGGGAGFMRGVKVERIYREVKVNAIG 362 ++ G+S + EI M KN AT +AVQ+ GG G+MR VER+YR+ ++ +IG Sbjct: 307 AKMAAGKSVIKEISMAKNFATDVADRLTYDAVQVL-GGMGYMRESLVERLYRDNRILSIG 365 Query: 363 GGTEEIMKDLASRQMGL 379 GG+ EIM ++ +QMGL Sbjct: 366 GGSREIMNEIIGKQMGL 382 >Rv0975c [I] COG1960 Acyl-CoA dehydrogenases Mtu Mycobacterium tuberculosis H37Rv Length = 382 Score = 294 bits (753), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 169/379 (44%), Positives = 242/379 (63%), Gaps = 4/379 (1%) Query: 3 NPFYTGEHEAFREVMRRFVAREIEPYAHQWDEDGEFPRELYAKASAIGLLGLGFPEEYGG 62 N + T E + R+ +R F REI P+ +W+ GE PR L+ A A GLLG GFPE GG Sbjct: 2 NIWTTPERQQLRKTVRAFAEREILPHVDEWERIGELPRGLHRLAGAAGLLGAGFPEAVGG 61 Query: 63 IAADQFMKIVASQELAQAGA-GGVSSSLMSHTIGSPPIARAARPEVKARVLPEVLAGKKI 121 D ++ +E+ QAGA GGV +SL + I P + + + A + LAG+KI Sbjct: 62 GGGDGADPVIICEEMHQAGAPGGVYASLFTCGIAVPHMVASGDERLIATYVRPTLAGEKI 121 Query: 122 SALAITEPSGGSDVANLRTRARREGDHYVVSGEKTFITSGMRADYLTVAVRTGGEGSGGV 181 ALAITEP GGSDV +LRT A R+GDHYV++G KT+ITSG+RADY+ AVRTGG G+ GV Sbjct: 122 GALAITEPGGGSDVGHLRTSAVRDGDHYVINGAKTYITSGVRADYVVTAVRTGGPGAAGV 181 Query: 182 SLLLIEGNTPGLSRT-KLKKMGWWASDTATLHFDECRVPVENLIGEEGQGFKIIMQNFNS 240 SLL++E +TPG T KL KMGW +SDTA L + + VP NL+G E GF I + F S Sbjct: 182 SLLVVEKDTPGFEVTRKLDKMGWRSSDTAELCYTDVAVPATNLVGAENSGFTQIARAFVS 241 Query: 241 ERMGMAASCTAYARVCLDEAVAYAKERKTFGKPIAQHQVIRHKIVDMAQKVAASQAMLEM 300 ER+G+AA + A+ CLD + ++R+TFG+P+ Q +++ + +MA+++ ++ Sbjct: 242 ERIGLAAQAYSSAQRCLDLTAQWCRDRETFGRPLISRQSVQNTLAEMARRIDVARVYAHH 301 Query: 301 LAWRLGHGESP-VAEICMMKNQATQTMAHCASEAVQIFGGGAGFMRGVKVERIYREVKVN 359 + R GE+ +A++C KN A Q A++AVQ+F GG G+M +VER YR++++ Sbjct: 302 VVERQLAGETDLIAQVCFAKNTAVQAGEWVANQAVQLF-GGMGYMAESEVERQYRDMRIL 360 Query: 360 AIGGGTEEIMKDLASRQMG 378 IGGGT EI+ LA++ +G Sbjct: 361 GIGGGTTEILTALAAKTLG 379 >MT1003 [I] COG1960 Acyl-CoA dehydrogenases MtC Mycobacterium tuberculosis CDC1551 Length = 382 Score = 294 bits (753), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 169/379 (44%), Positives = 242/379 (63%), Gaps = 4/379 (1%) Query: 3 NPFYTGEHEAFREVMRRFVAREIEPYAHQWDEDGEFPRELYAKASAIGLLGLGFPEEYGG 62 N + T E + R+ +R F REI P+ +W+ GE PR L+ A A GLLG GFPE GG Sbjct: 2 NIWTTPERQQLRKTVRAFAEREILPHVDEWERIGELPRGLHRLAGAAGLLGAGFPEAVGG 61 Query: 63 IAADQFMKIVASQELAQAGA-GGVSSSLMSHTIGSPPIARAARPEVKARVLPEVLAGKKI 121 D ++ +E+ QAGA GGV +SL + I P + + + A + LAG+KI Sbjct: 62 GGGDGADPVIICEEMHQAGAPGGVYASLFTCGIAVPHMVASGDERLIATYVRPTLAGEKI 121 Query: 122 SALAITEPSGGSDVANLRTRARREGDHYVVSGEKTFITSGMRADYLTVAVRTGGEGSGGV 181 ALAITEP GGSDV +LRT A R+GDHYV++G KT+ITSG+RADY+ AVRTGG G+ GV Sbjct: 122 GALAITEPGGGSDVGHLRTSAVRDGDHYVINGAKTYITSGVRADYVVTAVRTGGPGAAGV 181 Query: 182 SLLLIEGNTPGLSRT-KLKKMGWWASDTATLHFDECRVPVENLIGEEGQGFKIIMQNFNS 240 SLL++E +TPG T KL KMGW +SDTA L + + VP NL+G E GF I + F S Sbjct: 182 SLLVVEKDTPGFEVTRKLDKMGWRSSDTAELCYTDVAVPATNLVGAENSGFTQIARAFVS 241 Query: 241 ERMGMAASCTAYARVCLDEAVAYAKERKTFGKPIAQHQVIRHKIVDMAQKVAASQAMLEM 300 ER+G+AA + A+ CLD + ++R+TFG+P+ Q +++ + +MA+++ ++ Sbjct: 242 ERIGLAAQAYSSAQRCLDLTAQWCRDRETFGRPLISRQSVQNTLAEMARRIDVARVYAHH 301 Query: 301 LAWRLGHGESP-VAEICMMKNQATQTMAHCASEAVQIFGGGAGFMRGVKVERIYREVKVN 359 + R GE+ +A++C KN A Q A++AVQ+F GG G+M +VER YR++++ Sbjct: 302 VVERQLAGETDLIAQVCFAKNTAVQAGEWVANQAVQLF-GGMGYMAESEVERQYRDMRIL 360 Query: 360 AIGGGTEEIMKDLASRQMG 378 IGGGT EI+ LA++ +G Sbjct: 361 GIGGGTTEILTALAAKTLG 379 >PA4435 [I] COG1960 Acyl-CoA dehydrogenases Pae Pseudomonas aeruginosa Length = 381 Score = 255 bits (652), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 139/375 (37%), Positives = 214/375 (57%), Gaps = 4/375 (1%) Query: 5 FYTGEHEAFREVMRRFVAREIEPYAHQWDEDGEFPRELYAKASAIGLLGLGFPEEYGGIA 64 ++ +HE FR+ +R+F+ +E P+ HQW++DG R L+ KA G+L PEEYGG+ Sbjct: 9 LFSSDHELFRDSVRKFLEQEAVPFHHQWEKDGHVDRALWNKAGEAGMLCSHLPEEYGGMG 68 Query: 65 ADQFMKIVASQELAQAGAGGVSSSLMSHTIGSPPIARAARPEVKARVLPEVLAGKKISAL 124 AD V +E+ +AG G+ SL S I +P I +K + LP++++G+ ++A+ Sbjct: 69 ADFLYSAVVIEEIGRAGLTGIGFSLHSD-IAAPYILHYGSEALKRKYLPKLVSGEMVAAI 127 Query: 125 AITEPSGGSDVANLRTRARREGDHYVVSGEKTFITSGMRADYLTVAVRTGGE-GSGGVSL 183 A+TEP GSD+ ++T A +GD YV++G KTFIT+G AD + V +T + G+ G+SL Sbjct: 128 AMTEPGAGSDLQGVKTTAVLDGDEYVINGSKTFITNGFLADLVIVVAKTDPKAGAKGISL 187 Query: 184 LLIEGNTPGLSRTK-LKKMGWWASDTATLHFDECRVPVENLIGEEGQGFKIIMQNFNSER 242 ++E TPG S+ K L+K+G A DT+ L F + R+P ENL+G++GQGF +MQ ER Sbjct: 188 FVVEAGTPGFSKGKRLEKVGMKAQDTSELFFQDVRIPRENLLGKDGQGFIYLMQELPQER 247 Query: 243 MGMAASCTAYARVCLDEAVAYAKERKTFGKPIAQHQVIRHKIVDMAQKVAASQAMLEMLA 302 + + A A L + Y +ERK FGK +A Q R K+ +MA ++ + ++ Sbjct: 248 LTVGIGALASAEAALQWTLDYTRERKAFGKSVADFQNTRFKLAEMATEIQVGRVFVDRCM 307 Query: 303 WRLGHGESPVAEICMMKNQATQTMAHCASEAVQIFGGGAGFMRGVKVERIYREVKVNAIG 362 G+ V M K T E VQ+ GG GFM V R + + +V I Sbjct: 308 ELHLQGKLDVPTAAMCKYWTTDLQCKVLDECVQLH-GGYGFMWEYPVARAWADARVQRIY 366 Query: 363 GGTEEIMKDLASRQM 377 GT EIMK++ +R + Sbjct: 367 AGTNEIMKEIIARAL 381 >BH3798 [I] COG1960 Acyl-CoA dehydrogenases Bha Bacillus halodurans Length = 380 Score = 249 bits (637), Expect = 6e-66, Method: Compositional matrix adjust. Identities = 156/378 (41%), Positives = 218/378 (57%), Gaps = 5/378 (1%) Query: 3 NPFYTGEHEAFREVMRRFVAREIEPYAHQWDEDGEFPRELYAKASAIGLLGLGFPEEYGG 62 N T E + ++++R F E+ P A + DE+ F RE++ + + +GL G+ +PEEYGG Sbjct: 2 NFLLTDEQQMIKKMVRDFAENEVAPTAEERDEEERFDREIFDQMAELGLTGIPWPEEYGG 61 Query: 63 IAADQFMKIVASQELAQAGAGGVSSSLMSH-TIGSPPIARAARPEVKARVLPEVLAGKKI 121 I AD ++A +EL++ A +L +H ++ S P+ + E K + L + GKKI Sbjct: 62 IGADYVSYVIAVEELSRVCAS-TGVTLSAHLSLASWPVYKFGTEEQKQQFLRPMAEGKKI 120 Query: 122 SALAITEPSGGSDVANLRTRARREGDHYVVSGEKTFITSGMRAD-YLTVAVRTGGEGSGG 180 A +TEP GSD AN++T A EGD Y+++G K FIT+G AD Y+ AV + G Sbjct: 121 GAYGLTEPGSGSDAANMKTTAVLEGDDYILNGSKIFITNGGIADIYIVFAVTEPEKRHKG 180 Query: 181 VSLLLIEGNTPGLSR-TKLKKMGWWASDTATLHFDECRVPVENLIGEEGQGFKIIMQNFN 239 VS ++E +TPG S K KK+G +S T + F++CRVP ENL+G+EG GFKI M + Sbjct: 181 VSAFIVEADTPGFSVGKKEKKLGIRSSPTTEIIFEDCRVPKENLLGKEGDGFKIAMMTLD 240 Query: 240 SERMGMAASCTAYARVCLDEAVAYAKERKTFGKPIAQHQVIRHKIVDMAQKVAASQAMLE 299 R G+AA A+ LD AVAYA ERK FGKPI Q Q I K+ DMA KV AS+ + Sbjct: 241 GGRNGIAAQAVGIAQGALDAAVAYANERKQFGKPIGQQQGIAFKLADMATKVEASRLLTY 300 Query: 300 MLAWRLGHGESPVAEICMMKNQATQTMAHCASEAVQIFGGGAGFMRGVKVERIYREVKVN 359 AWR G S E M K A T EAVQ+F GG G+ + VER R+ K+ Sbjct: 301 QAAWRESEGLSYGKESAMSKLFAGDTAMDVTVEAVQVF-GGYGYTKEYPVERYMRDAKIT 359 Query: 360 AIGGGTEEIMKDLASRQM 377 I GT EI + + S+ + Sbjct: 360 QIYEGTNEIQRLVISKML 377