BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0041.0048.p         (141 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AGpA470 [HE] COG0111 Phosphoglycerate dehydrogenase and related ...    80   2e-15
MK0297 [HE] COG0111 Phosphoglycerate dehydrogenase and related d...    70   1e-12
BMEI0349 [HE] COG0111 Phosphoglycerate dehydrogenase and related...    69   2e-12
MJ1018 [HE] COG0111 Phosphoglycerate dehydrogenase and related d...    65   3e-11
mll3875 [HE] COG0111 Phosphoglycerate dehydrogenase and related ...    65   4e-11

>AGpA470 [HE] COG0111 Phosphoglycerate dehydrogenase and related
           dehydrogenases Atu Agrobacterium tumefaciens strain C58
           (Cereon)
          Length = 354

 Score = 79.7 bits (195), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 51/142 (35%), Positives = 79/142 (55%), Gaps = 11/142 (7%)

Query: 3   ASFRVLVTGDSLAPAAVNVLSEIGADVVLMHDAVTPERLAHEMARA-----PTQAILMRG 57
            S  +LVTG ++   AV ++++ G  V      V P     ++ R      P   ++  G
Sbjct: 26  GSRNILVTGPAINEQAVKLITDNGYQV----SYVPPYTSEADLVRIVTELDPVGVVVRMG 81

Query: 58  NPVFSAATIAGNPHLRVIAKHGAGVDSVDIDAATASRVLVMVAGDANAPAVAEHTIALIL 117
              FS A I   P LRV++KHG GVD++D+DAA+   + V+VA  ANA +VAEH I L+ 
Sbjct: 82  R--FSEAAIKAAPSLRVLSKHGVGVDNIDVDAASRREIPVVVAAGANALSVAEHAITLLF 139

Query: 118 ALGRDVVSLNTRTRTGAWDRAA 139
           A+ + +V L++  R G W++A 
Sbjct: 140 AVVKRIVPLDSGIRAGRWEKAG 161


>MK0297 [HE] COG0111 Phosphoglycerate dehydrogenase and related
           dehydrogenases Mka Methanopyrus kandleri AV19
          Length = 522

 Score = 70.1 bits (170), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 47/132 (35%), Positives = 75/132 (56%), Gaps = 5/132 (3%)

Query: 6   RVLVTGDSLAPAAVNVLSEIGADVVLMHDAVTPERLAHEMARAPTQAILMRGNPVFSAAT 65
           ++LVT D +   A+  L E+G +VV++ DA   E   H        A ++R     +   
Sbjct: 3   KILVT-DPIHEDALRKLEELG-EVVVLEDADEEEIREH---VRDADAWVVRSGTRVTREL 57

Query: 66  IAGNPHLRVIAKHGAGVDSVDIDAATASRVLVMVAGDANAPAVAEHTIALILALGRDVVS 125
           I    +L+VIA+ G GVD++D+ AAT   ++V+ A ++++ +VAEHT+ LILAL R +  
Sbjct: 58  IEEAKNLKVIARAGVGVDNIDVKAATERGIIVVNAPESSSISVAEHTMGLILALARKIPQ 117

Query: 126 LNTRTRTGAWDR 137
            +   R G WDR
Sbjct: 118 ADRSVRRGEWDR 129


>BMEI0349 [HE] COG0111 Phosphoglycerate dehydrogenase and related
           dehydrogenases Bme Brucella melitensis
          Length = 538

 Score = 69.3 bits (168), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 47/133 (35%), Positives = 69/133 (51%), Gaps = 4/133 (3%)

Query: 6   RVLVTGDSLAPAAVNVLSEIGADVVLMHD-AVTPERLAHEMARAPTQAILMRGNPVFSAA 64
           RVLV+ D L+P AV +  + G DV  + D     E+L   +      AI  R     +  
Sbjct: 9   RVLVS-DKLSPTAVQIFKDRGVDVDYLPDLGKDKEKLLEVIGEYDGLAI--RSATKVTEK 65

Query: 65  TIAGNPHLRVIAKHGAGVDSVDIDAATASRVLVMVAGDANAPAVAEHTIALILALGRDVV 124
            IA    L+V+ + G GVD+VDI AA+   ++VM     N+   AEH IAL+ A+ R + 
Sbjct: 66  LIAAAKKLKVVGRAGIGVDNVDIPAASRRGIIVMNTPFGNSITTAEHAIALMFAVARQLP 125

Query: 125 SLNTRTRTGAWDR 137
             +T TR G W++
Sbjct: 126 EADTSTRAGKWEK 138


>MJ1018 [HE] COG0111 Phosphoglycerate dehydrogenase and related
           dehydrogenases Mja Methanococcus jannaschii
          Length = 524

 Score = 65.5 bits (158), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 43/132 (32%), Positives = 73/132 (55%), Gaps = 5/132 (3%)

Query: 6   RVLVTGDSLAPAAVNVLSEIGADVVLMHDAVTPERLAHEMARAPTQAILMRGNPVFSAAT 65
           ++LVT D L   A+ +L E+G   V +   +T E L  ++  A    +++R     +   
Sbjct: 3   KILVT-DPLHEDAIKILEEVGE--VEVATGLTKEELLEKIKDA--DVLVVRSGTKVTRDV 57

Query: 66  IAGNPHLRVIAKHGAGVDSVDIDAATASRVLVMVAGDANAPAVAEHTIALILALGRDVVS 125
           I     L+VI + G GVD++D++AAT   ++V+ A DA++ +VAE T+ L+LA  R++  
Sbjct: 58  IEKAEKLKVIGRAGVGVDNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQ 117

Query: 126 LNTRTRTGAWDR 137
                + G WDR
Sbjct: 118 ATASLKRGEWDR 129


>mll3875 [HE] COG0111 Phosphoglycerate dehydrogenase and related
           dehydrogenases Mlo Mesorhizobium loti
          Length = 533

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 4/133 (3%)

Query: 6   RVLVTGDSLAPAAVNVLSEIGADVVLMHD-AVTPERLAHEMARAPTQAILMRGNPVFSAA 64
           RVLV+ D L+P AV +  + G +V  + D     E+L   + +    AI  R     +  
Sbjct: 4   RVLVS-DKLSPTAVQIFKDRGVEVDYLPDLGKDKEKLLEVIDQYDGLAI--RSATKVTEK 60

Query: 65  TIAGNPHLRVIAKHGAGVDSVDIDAATASRVLVMVAGDANAPAVAEHTIALILALGRDVV 124
            I     L+VI + G GVD+VDI AA+   ++VM     N+   AEH +A+I AL R + 
Sbjct: 61  LINAATRLKVIGRAGIGVDNVDIPAASRKGIIVMNTPFGNSITTAEHAVAMIFALARQIP 120

Query: 125 SLNTRTRTGAWDR 137
             N  T  G W++
Sbjct: 121 EANASTHAGKWEK 133