BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0041.0030.p (218 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc4521 [P] COG0288 Carbonic anhydrase Atu Agrobacterium tumefac... 226 3e-59 mlr4135 [P] COG0288 Carbonic anhydrase Mlo Mesorhizobium loti 222 4e-58 SMc04083 [P] COG0288 Carbonic anhydrase Sme Sinorhizobium meliloti 219 4e-57 BMEI0222 [P] COG0288 Carbonic anhydrase Bme Brucella melitensis 219 5e-57 Cj0237 [P] COG0288 Carbonic anhydrase Cje Campylobacter jejuni 142 4e-34 >AGc4521 [P] COG0288 Carbonic anhydrase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 213 Score = 226 bits (575), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 102/208 (49%), Positives = 147/208 (70%), Gaps = 1/208 (0%) Query: 1 MKFFPKQLIDGYRTFATQRLPTEQSRYRDLSERGQFPETMVIGCCDSRVSPEVIFDAGPG 60 MK FP+ L++GY+ F + R E+ RYR L++ GQ P+T+ I CCDSR +PE IFD GPG Sbjct: 1 MKDFPETLLNGYKNFMSGRYVDERERYRVLADTGQKPQTLFIACCDSRSAPETIFDCGPG 60 Query: 61 ELFVVRNIANLVPVYQPDSNAHGVSAALEYAVTVLKVKNIVVLGHAQCGGIRAFVD-KIK 119 ELFVVRN+AN+VP ++PD H SAA+EYAV VLKVK+IVV+GH +CGGI+A +D ++ Sbjct: 61 ELFVVRNVANMVPPFEPDGQYHATSAAIEYAVQVLKVKDIVVMGHGRCGGIQAALDPNLE 120 Query: 120 PLTPGDFIGKWMQMFIKPGEVVEQREHETMQDFVVRIEKAAVFRSLENLMTFPFVRERVE 179 PL+PGDFIGKWM M E ++ + T + +E+ ++ S+ NL FPFV+ + Sbjct: 121 PLSPGDFIGKWMNMVKSAAEQIQSNDVMTASERQTALERVSIRNSIANLRGFPFVKAQET 180 Query: 180 SGEMQLHGAYFGVAEGSLFVLDRVAKEF 207 +G+++LHGA+F ++ G L+V+D +F Sbjct: 181 AGKVKLHGAWFDISTGELWVMDSKTGDF 208 >mlr4135 [P] COG0288 Carbonic anhydrase Mlo Mesorhizobium loti Length = 214 Score = 222 bits (566), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 104/208 (50%), Positives = 134/208 (64%), Gaps = 1/208 (0%) Query: 1 MKFFPKQLIDGYRTFATQRLPTEQSRYRDLSERGQFPETMVIGCCDSRVSPEVIFDAGPG 60 M P L+ GYR F R TE RYR+L+ GQ PETM++ CCDSR +PE IFDAGPG Sbjct: 1 MPHLPDHLLAGYRNFMNGRYLTESGRYRELAREGQAPETMIVACCDSRAAPEAIFDAGPG 60 Query: 61 ELFVVRNIANLVPVYQPDSNAHGVSAALEYAVTVLKVKNIVVLGHAQCGGIRAFVD-KIK 119 ELFV+RN+ NLVP Y+PD H SAALE+AV LKVKNIVV+GH +CGGIRA +D Sbjct: 61 ELFVLRNVGNLVPPYEPDGEFHSTSAALEFAVQSLKVKNIVVMGHGRCGGIRAALDPNAA 120 Query: 120 PLTPGDFIGKWMQMFIKPGEVVEQREHETMQDFVVRIEKAAVFRSLENLMTFPFVRERVE 179 PL+PGDFIGKWM + E V T + +E+ ++ S+ NL TFP V Sbjct: 121 PLSPGDFIGKWMSLIAPAAETVSSSTFMTAAERQTALERISIRYSIANLRTFPCVSILEG 180 Query: 180 SGEMQLHGAYFGVAEGSLFVLDRVAKEF 207 G + LHGA+F ++ G L+V+++ +F Sbjct: 181 KGRLSLHGAWFDISTGELWVMNKETGDF 208 >SMc04083 [P] COG0288 Carbonic anhydrase Sme Sinorhizobium meliloti Length = 227 Score = 219 bits (558), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 99/205 (48%), Positives = 141/205 (68%), Gaps = 1/205 (0%) Query: 4 FPKQLIDGYRTFATQRLPTEQSRYRDLSERGQFPETMVIGCCDSRVSPEVIFDAGPGELF 63 FP+ L+ GYR F + R +Q RY+ L+E GQ P+TMVI CCDSR +PE IFD+GPGELF Sbjct: 18 FPEHLLTGYRNFMSGRFNEQQQRYKTLAESGQKPKTMVIACCDSRAAPETIFDSGPGELF 77 Query: 64 VVRNIANLVPVYQPDSNAHGVSAALEYAVTVLKVKNIVVLGHAQCGGIRAFVD-KIKPLT 122 VVRN+AN++P Y+PD + H SAALE+AV L+V NIVV+GH +CGGI+A +D +PL+ Sbjct: 78 VVRNVANMMPPYEPDGHYHSTSAALEFAVQSLRVTNIVVMGHGRCGGIKAALDPDAEPLS 137 Query: 123 PGDFIGKWMQMFIKPGEVVEQREHETMQDFVVRIEKAAVFRSLENLMTFPFVRERVESGE 182 PGDFIG+WM + E ++ + T + +E+ ++ S+ NL TFP V G+ Sbjct: 138 PGDFIGRWMNLLKPAAEQIQSNDVMTQAERQRALERVSIRNSIANLRTFPCVNILESKGK 197 Query: 183 MQLHGAYFGVAEGSLFVLDRVAKEF 207 ++LHGA+F ++ G L+V+D +F Sbjct: 198 LRLHGAWFDISTGELWVMDAKTGDF 222 >BMEI0222 [P] COG0288 Carbonic anhydrase Bme Brucella melitensis Length = 213 Score = 219 bits (557), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 99/208 (47%), Positives = 139/208 (66%), Gaps = 1/208 (0%) Query: 1 MKFFPKQLIDGYRTFATQRLPTEQSRYRDLSERGQFPETMVIGCCDSRVSPEVIFDAGPG 60 M P L+ GY+TF ++ E +RYRDL+E+GQ PET+V+ CCDSR +PE IF+A PG Sbjct: 1 MADLPDSLLAGYKTFMSEHFAHETARYRDLAEKGQSPETLVVACCDSRAAPETIFNAAPG 60 Query: 61 ELFVVRNIANLVPVYQPDSNAHGVSAALEYAVTVLKVKNIVVLGHAQCGGIRAFVD-KIK 119 E+FV+RN+ANL+P Y+PD H SAALE+AV LKVK+IVV+GH +CGGI+A +D + Sbjct: 61 EIFVLRNVANLIPPYEPDGEYHAASAALEFAVQSLKVKHIVVMGHGRCGGIKAALDTESA 120 Query: 120 PLTPGDFIGKWMQMFIKPGEVVEQREHETMQDFVVRIEKAAVFRSLENLMTFPFVRERVE 179 PL+P DFIGKWM + E + T + +E+ ++ SL NL TFP V + Sbjct: 121 PLSPSDFIGKWMSLISPAAEAISGNALMTQSERHTALERISIRYSLANLRTFPCVDILEK 180 Query: 180 SGEMQLHGAYFGVAEGSLFVLDRVAKEF 207 G++ LHGA+F ++ G L+V+D +F Sbjct: 181 KGKLTLHGAWFDISTGELWVMDHQTGDF 208 >Cj0237 [P] COG0288 Carbonic anhydrase Cje Campylobacter jejuni Length = 211 Score = 142 bits (359), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 74/210 (35%), Positives = 120/210 (57%), Gaps = 5/210 (2%) Query: 6 KQLIDGYRTFATQRLPTEQSRYRDLSERGQFPETMVIGCCDSRVSPEVIFDAGPGELFVV 65 + LI G F + + + L + Q P T+ IGC DSRV P +I + GPGELFV+ Sbjct: 2 ENLISGAIKFMQEDFKEHEELFESLKNK-QNPHTLFIGCSDSRVIPNLITNTGPGELFVI 60 Query: 66 RNIANLVPVYQPDSNAHGVSAALEYAVTVLKVKNIVVLGHAQCGGIRAFVDKIKPLTPGD 125 RNIAN+VP Y+ + ++A+EYA+ L +KNIVV GH+ CGG A + L Sbjct: 61 RNIANIVPPYRVGEDYLATTSAIEYALNSLHIKNIVVCGHSNCGGCNALYYSDEELNKIP 120 Query: 126 FIGKWMQMF--IKPGEVVEQREHETMQDFVVRIEKAAVFRSLENLMTFPFVRERVESGEM 183 + KW+ M IK ++ R+ M+ ++ EK + SL+N++T+P V+E ++ G++ Sbjct: 121 NVKKWLTMLDPIKKDVMIFARDDLAMRSWLT--EKLNLVNSLQNILTYPGVQEALDEGKI 178 Query: 184 QLHGAYFGVAEGSLFVLDRVAKEFISVRDQ 213 ++H Y+ + G ++ D AK F ++D+ Sbjct: 179 EVHAWYYIIETGEIYEYDFKAKIFTLIQDR 208