BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0041.0009.p (401 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Ta1034 [GEPR] COG0477 Permeases of the major facilitator superfa... 68 4e-11 SSO0992 [GEPR] COG0477 Permeases of the major facilitator superf... 67 7e-11 DR1743 [GEPR] COG0477 Permeases of the major facilitator superfa... 63 9e-10 TVN0561 [GEPR] COG0477 Permeases of the major facilitator superf... 62 2e-09 >Ta1034 [GEPR] COG0477 Permeases of the major facilitator superfamily Tac Thermoplasma acidophilum Length = 414 Score = 67.8 bits (164), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 74/288 (25%), Positives = 132/288 (45%), Gaps = 23/288 (7%) Query: 19 RTLTVTGLNHALHDGYTDVIYVLLPVWQAEFALSYGLLALLRGLYAGAMAGLQIPVGRIA 78 R+L T L H +D + VL+ + ++F +S LL + +Y+ L PVGR A Sbjct: 14 RSLVYTSLGHFTNDFNILLFSVLITYYHSDFGISLALLGAVAIIYSIISGLLSTPVGRYA 73 Query: 79 ER--------IDGKIILIAGTALSALGYAFAGFSGGVIGLGLALALSGAGSSTQHPIASA 130 ++ + G IIL L AL + A + V + +A L G G + HP+ S+ Sbjct: 74 DKTRRYRFLMMVGFIILGVSIYLFALSFVSARIALPV--MIVASILFGFGQAFYHPLGSS 131 Query: 131 AVSRAYGTAARGPLGVYNFSGDLGKAAIPALTSILLVIMSWRHTLLVLAFAGLLVAVCIA 190 ++ YG + LG+ G +G++A+P + L++++ ++ L++L +L + I Sbjct: 132 ILNLTYGNGSASALGINGAFGSIGRSALPVILVPLIILVGEKYALVILGTYMILAGIII- 190 Query: 191 LWMPSVGKGAEHKATSASRGASTGGG------FRWLLAIGILDTAVRMGFL----TFLPF 240 +G EH+ SR AS+ + +LAI + +R FL T++ Sbjct: 191 --YAGLGFIREHEIPEKSRSASSSKNRDMLSRYSGVLAIIVAMVFIRAMFLTGTTTYISQ 248 Query: 241 LLRDKGASLPTNGLALALVFIGGAAGKFTCGWLGERVGTLRTVLITEG 288 + D+ S + L + F+ G+ G L +R G T+ +T G Sbjct: 249 FVLDRVKSETIMSIVLTVSFLTAVGGQPYFGRLTQRHGGKVTIGLTTG 296 >SSO0992 [GEPR] COG0477 Permeases of the major facilitator superfamily Sso Sulfolobus solfataricus Length = 396 Score = 67.0 bits (162), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 109/388 (28%), Positives = 172/388 (44%), Gaps = 28/388 (7%) Query: 19 RTLTVTGLNHALHDGYTDVIYVLLPVWQAEFALSYGLLALLRGLYAGAMAGLQIP-VGRI 77 R LT+T L+H ++DG + V+ V +S L+ +L G + ++ L P V +I Sbjct: 4 RILTLTSLSHFINDGNSWVLPVTFIFLITYLGISKFLIGILSGAFFFGISALASPLVSKI 63 Query: 78 AER------IDGKIILIAGTALSALGYAFAGFSGGVIGLGLALALSGAGSSTQHPIASAA 131 A++ I G IL+ G L + GY+ ++ + +A+A G S+ HPI +A Sbjct: 64 ADKFTNYSSIMGIGILLWGIGLISFGYSIQLHFLPLVFISVAIA--GFASAFYHPIGAAV 121 Query: 132 VSRAYGTAARGPLGVYNFSGDLGKAAIPALTSILLVIMSWRHTLLVLAFAGLLVAVCI-A 190 +S Y A LG+ G LG+A P LT L I++ TL +L + + + + Sbjct: 122 LSITYKGNAGIALGINGSMGSLGRAIYPTLTLSLFAILNKDMTLDMLIIGIISIIAALPS 181 Query: 191 LWMP-SVGKGAEHKATSASRGASTGGGFR---WLLAIGILDTAVRMGFLTFLPFLL-RDK 245 +++ S+ K +HK S+S ST G L I +L + G FLP LL + Sbjct: 182 IFLKISITKEEDHKTPSSSNTTSTRGTLFVVILLTIIALLRSIFGQGISQFLPTLLVENY 241 Query: 246 GASLPTN-GLALALVFIGGAAGKFTCGWLGERVGTLRTVLITEGGTAALIAAVLALPLAP 304 G S N G A+ + G+ G+L +RVG I+ G A + L + P Sbjct: 242 GYSYNVNLGEAITIALAAAIVGQPILGFLSDRVGRRLIYAISTFGAALTLLLFLKI---P 298 Query: 305 AIVLLPLLGVMLNGTSSVLYGTVPELTPAHQTERAFALFY-TGTIGSGAIAPVLYG---- 359 I LL L G ++ V + P + A +L + G G G I P++ G Sbjct: 299 NIALLSLFGFFNFSAFPLMLSIVGDFVPRNSASFANSLVWGLGVTGGGVIGPIVVGAVSQ 358 Query: 360 ----LLGDALGPTLATAATALTALAICP 383 + + +A A ALTAL P Sbjct: 359 VSNLVFASEIVTIMAFVAGALTALIPKP 386 >DR1743 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 409 Score = 63.2 bits (152), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 64/252 (25%), Positives = 110/252 (43%), Gaps = 8/252 (3%) Query: 28 HALHDGYTDVIYVLLPVWQAEFALSYGLLALLRGLYAGAMAGLQIPVGRIAERIDGKIIL 87 H ++D Y ++ L P Q+++ ++ + LL +++ + LQ +G + ERID + Sbjct: 44 HFINDAYGAMLTPLTPALQSKYGVTIAAVTLLSSVFSLTSSVLQPLLGIVGERIDRRYAA 103 Query: 88 IAGTALSALGYAFAGFSGGVIGLGLALALSGAGSSTQHPIASAAVSRAYGTAARGPL-GV 146 G ++ +G GF L L +A++G GS HP SA V++ RG + Sbjct: 104 ALGPLMTGVGLTLMGFVPWFGALILLVAVAGFGSGFFHPAGSAYVAQNSPADKRGLWASI 163 Query: 147 YNFSGDLGKAAIPALTSILLVIMSWRHTLLVLAFAGLLVAVCIALWMPSVGKGAEHKATS 206 ++ G G A P + L + W A G ++A + PS + A+ + Sbjct: 164 FSAGGTAGMALGPVFAGVGLTHLPW------FALIGAVIAAVTFVVTPSGAQKAKRVGLA 217 Query: 207 ASRGASTGGGFRWLLAIGILDTAVRMGFLTFLPFLLRDKGASLPTNGLALALVFIGGAAG 266 G G WL + +L + MG+ LPF+L +G G LA+ + A G Sbjct: 218 EYAGIFR-GPLVWLWGMAVLRSLASMGYNAMLPFMLMARGFGAREVGTTLAIYAVASAFG 276 Query: 267 KFTCGWLGERVG 278 G L ++ G Sbjct: 277 GILGGRLSDKYG 288 >TVN0561 [GEPR] COG0477 Permeases of the major facilitator superfamily Tvo Thermoplasma volcanium Length = 415 Score = 62.4 bits (150), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 70/290 (24%), Positives = 129/290 (44%), Gaps = 18/290 (6%) Query: 11 RPDRARSTRTLTVTGLNHALHDGYTDVIYVLLPVWQAEFALSYGLLALLRGLYAGAMAGL 70 RP+R ++ LT T L H +D + VL+ + F +S LL + +Y L Sbjct: 9 RPERIKA---LTFTSLGHFTNDFNILLFSVLITYYHRYFGISLALLGAIAIIYNIISGFL 65 Query: 71 QIPVGRIAERIDGKI------ILIAGTALSALGYAFAGFSGGVIGLGLALALSGAGSSTQ 124 P+GR A++ I I G +L G++F S + + +A+ G G + Sbjct: 66 STPIGRYADKTRAYRGLMMLGIFILGVSLFLFGFSFLSASFVIWIMLIAVIFLGIGQAFY 125 Query: 125 HPIASAAVSRAYGTAARGPLGVYNFSGDLGKAAIPALTSILLVIMSWRHTLLV----LAF 180 HP+ + ++ YG A LG+ G +G++A+P + L++++ + L V + Sbjct: 126 HPLGGSILNVTYGERAASALGINGAFGSIGRSALPVILVPLILLVGKAYALFVAGTYMFV 185 Query: 181 AGLLVAVCIALWMPSVGKGAEHKATSASRGASTGGGFRWLLAIGILDTAVRMGFL----T 236 AG+++ ++ +A+SA+ T +R +LAI + +R FL T Sbjct: 186 AGVVIYAGLSFLKKREIPNRSREASSAAN-KETYLRYRGVLAIIVAMIFIRAMFLTGTTT 244 Query: 237 FLPFLLRDKGASLPTNGLALALVFIGGAAGKFTCGWLGERVGTLRTVLIT 286 ++ + D+ S L + F+ G+ G L E+ G ++ IT Sbjct: 245 YISQFVLDRVKSEILMSYILTISFLTAVIGQPVFGRLTEKYGGKWSISIT 294