BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0041.0003.p (358 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc4888 [R] COG2220 Predicted Zn-dependent hydrolases of the bet... 330 4e-90 mlr4314 [R] COG2220 Predicted Zn-dependent hydrolases of the bet... 320 4e-87 XF2024 [R] COG2220 Predicted Zn-dependent hydrolases of the beta... 276 7e-74 PA3969 [R] COG2220 Predicted Zn-dependent hydrolases of the beta... 259 7e-69 RSp1389 [R] COG2220 Predicted Zn-dependent hydrolases of the bet... 185 1e-46 >AGc4888 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 378 Score = 330 bits (845), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 165/293 (56%), Positives = 202/293 (68%), Gaps = 4/293 (1%) Query: 32 YDGPVSDHFDGLHFFDPDGSPPKSLGEVLRWQFGGGRQRAVWPEWAPSPHA-DTPPPRVD 90 Y GP+SDHFDG+ FF+P G+PP + +L+W+F G +RA WPE PSP P R+D Sbjct: 55 YSGPISDHFDGVRFFNPGGTPPGNFMGLLKWRFNG--ERATWPETYPSPFPFAKPEARID 112 Query: 91 GDRVRFCFVGHASWLIQTAGLNILFDPVWSMRASPFSFAGPKRHNDPGIAFEKLPRIDVV 150 G +R FVGHAS+LIQTAGLNIL DPVWS R SP SFAGPKR N PGI FE LP ID+V Sbjct: 113 GRDMRVTFVGHASFLIQTAGLNILVDPVWSQRTSPLSFAGPKRVNPPGIRFEDLPPIDLV 172 Query: 151 LVSHGHYDHLDVATLSRLAGAFGSRVITPLGNDVTMRTSDAAIKAEAFDWHQRIELGNGL 210 LV+H HYDHLD+ TL RL A ITPLGND +RT A + + DW +E G+ + Sbjct: 173 LVTHNHYDHLDMETLKRLHVAHKPLFITPLGNDAVIRTGVEAARIKVGDWGDVVETGS-V 231 Query: 211 AATLVPTRHWSARGLFDRNKALWASFVLETPAGKLYIVGDSGYGDGGHFRRVAEAHGPLR 270 P HWSARGL DR+ ALWA+FV+ETP GK+Y +GD+G+ +G ++ + HG R Sbjct: 232 KIHFEPCHHWSARGLNDRSMALWAAFVIETPGGKIYHIGDTGFHEGLNYGAARKKHGEFR 291 Query: 271 LAILPIGAYEPRWFMRDQHMNPEDAVKALADCGAAQALAHHHGTFQLTDEAID 323 LA LP GAYEPRWFM+ QH NP +AV+ + CGAA HH GT QLTDEA+D Sbjct: 292 LANLPFGAYEPRWFMKGQHQNPAEAVEGMRLCGAAHVCGHHWGTVQLTDEAVD 344 >mlr4314 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold Mlo Mesorhizobium loti Length = 350 Score = 320 bits (819), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 162/297 (54%), Positives = 198/297 (66%), Gaps = 3/297 (1%) Query: 30 KTYDGPVSDHFDGLHFFDPDGSPPKSLGEVLRWQFGGGRQRAVWPEWAPSPHADT-PPPR 88 + Y GP SDHFDG FF+P G P ++L+WQF G QRA WP +PSP P + Sbjct: 21 RYYSGPPSDHFDGTLFFNPGGQMPGRFTDLLKWQFNG--QRAKWPATSPSPFPQARPAAK 78 Query: 89 VDGDRVRFCFVGHASWLIQTAGLNILFDPVWSMRASPFSFAGPKRHNDPGIAFEKLPRID 148 V+G + VGH++ LIQTAGLNIL DPVWS R SPFSFAGPKR N PGI F+ LP ID Sbjct: 79 VEGTDLTVTMVGHSTLLIQTAGLNILTDPVWSQRTSPFSFAGPKRVNAPGIVFDDLPPID 138 Query: 149 VVLVSHGHYDHLDVATLSRLAGAFGSRVITPLGNDVTMRTSDAAIKAEAFDWHQRIELGN 208 +VLVSH HYDHLD+ATL RL V+TPLGNDV + + ++ A DW ++++ + Sbjct: 139 LVLVSHNHYDHLDLATLKRLKEKHDPLVVTPLGNDVLIGEAVPDMRLSAHDWGDKVDIAD 198 Query: 209 GLAATLVPTRHWSARGLFDRNKALWASFVLETPAGKLYIVGDSGYGDGGHFRRVAEAHGP 268 A + P HWSARG DR ALWA FV+ETP GKLY GD+G+ DG ++R +A+ HG Sbjct: 199 RAAIHIEPAHHWSARGARDRRMALWAGFVIETPGGKLYFAGDTGFHDGINYRLMADKHGG 258 Query: 269 LRLAILPIGAYEPRWFMRDQHMNPEDAVKALADCGAAQALAHHHGTFQLTDEAIDAP 325 R AILPIGAYEPRWFM QH NP +AV+ + C AA A H GTF LTDE +D P Sbjct: 259 FRFAILPIGAYEPRWFMAPQHQNPREAVQGMKLCKAAFAAGCHWGTFHLTDEPMDEP 315 >XF2024 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold Xfa Xylella fastidiosa 9a5c Length = 332 Score = 276 bits (705), Expect = 7e-74, Method: Compositional matrix adjust. Identities = 150/303 (49%), Positives = 188/303 (62%), Gaps = 8/303 (2%) Query: 26 MSLMKTYDGPVSDHFDGLHFFDPDGSPP--KSLGEVLRWQFGGGRQRAVWPEWAPSPHAD 83 M + Y GP+SDHFDGL FF+P G P K ++LRW++ R W + P H Sbjct: 1 MPHNRYYQGPLSDHFDGLRFFNP-GQPNTDKPFSDLLRWRWES-RHLPPWRD-VPPTHVA 57 Query: 84 TPPPRVDGDRVRFCFVGHASWLIQTAGLNILFDPVWSMRASPFSFAGPKRHNDPGIAFEK 143 TP R + +GH+S LIQ AGLN+L DPVWS R SP S+ GP+R N PGI F Sbjct: 58 TPIARSQHPII--TMIGHSSVLIQIAGLNLLVDPVWSERVSPLSWLGPRRWNSPGIDFNA 115 Query: 144 LPRIDVVLVSHGHYDHLDVATLSRLAGAFGSRVITPLGNDVTMRTSDAAIKAEAFDWHQR 203 LP ID VL++H HYDHLD+ TL+RL A +V+TPLGND +R + DW Sbjct: 116 LPPIDYVLITHNHYDHLDLTTLARLQIAHAPQVVTPLGNDAIIRKRVPDLHIHTLDWWDS 175 Query: 204 IELGNG-LAATLVPTRHWSARGLFDRNKALWASFVLETPAGKLYIVGDSGYGDGGHFRRV 262 I+L N ++VP HWSARGL DR ALW F L TP G LYI GD+ YG+G F + Sbjct: 176 IQLTNEPTKISVVPAYHWSARGLRDRCMALWGGFHLHTPQGSLYIAGDTAYGNGSIFHAI 235 Query: 263 AEAHGPLRLAILPIGAYEPRWFMRDQHMNPEDAVKALADCGAAQALAHHHGTFQLTDEAI 322 A+ G LAILPIGAY PRWFM +QH++ +AV+ + D GA QAL H GTF+LTDEA+ Sbjct: 236 AQRCGAPDLAILPIGAYAPRWFMHNQHIDAVEAVQIMCDVGAHQALGVHWGTFRLTDEAV 295 Query: 323 DAP 325 + P Sbjct: 296 EEP 298 >PA3969 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold Pae Pseudomonas aeruginosa Length = 361 Score = 259 bits (662), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 144/309 (46%), Positives = 187/309 (60%), Gaps = 11/309 (3%) Query: 32 YDGPVSDHFDGLHFFDPDGSPPKSLGEVLRWQFGGGRQRAVWPEWAPSPHADTPP---PR 88 Y GP SDHFDG F + + KSL ++L+WQ+ QR W P TPP R Sbjct: 23 YQGPPSDHFDGERFRNIQPTAHKSLRDLLKWQWNRPPQRP----WVALPPTATPPRVNER 78 Query: 89 VDGDRVRFCFVGHASWLIQTAGLNILFDPVWSMRASPFSFAGPKRHNDPGIAFEKLPRID 148 G+ +R ++ HA+ LIQ GLNIL DPVWS R SP +F GPKRH+ PG+ ++LP ID Sbjct: 79 ARGEELRVTYINHATLLIQHRGLNILTDPVWSQRVSPLAFIGPKRHHPPGLTLDQLPPID 138 Query: 149 VVLVSHGHYDHLDVATLSRLAGAFGS-RVITPLGNDVTMRTSDAAIKAEAFDWHQRIELG 207 +VLVSH HYDHLD+ TL +L + + +V++ LGN +R + A E DW Q + LG Sbjct: 139 LVLVSHNHYDHLDLETLRQLHRRWPTAKVVSGLGNAGLIRQTGFADVVE-IDWWQAVPLG 197 Query: 208 NGLAATLVPTRHWSARGLFDRNKALWASFVLETPAGKLYIVGDSGYGDGGHFRRVAEAHG 267 GL VP +HWS+R D N+ LW FV+++P G L GD+G G F + + G Sbjct: 198 AGLTLHGVPVQHWSSRTRSDTNRTLWLGFVIDSPDGPLLFPGDTGLGP--EFGLINQRFG 255 Query: 268 PLRLAILPIGAYEPRWFMRDQHMNPEDAVKALADCGAAQALAHHHGTFQLTDEAIDAPAI 327 +R A LPIGAYEPRWFMRD HMNP+DAV+A A ++A H GTF LTDE D P Sbjct: 256 AMRFAALPIGAYEPRWFMRDHHMNPDDAVQAHRTLQAQTSMAIHFGTFNLTDEQQDDPPK 315 Query: 328 AHRGARRGE 336 A + A R + Sbjct: 316 ALQAALRSQ 324 >RSp1389 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold Rso Ralstonia solanacearum Length = 362 Score = 185 bits (470), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 100/240 (41%), Positives = 135/240 (56%), Gaps = 12/240 (5%) Query: 95 RFCFVGHASWLIQTAGLNILFDPVWSMRASPFSFAGPKRHNDPGIAFEKLPRIDVVLVSH 154 + ++GH + L+Q GLN+L DPV+ RASP FAGP+RH PG++ +LP ID+VL+SH Sbjct: 71 QVTWIGHETLLLQIDGLNVLTDPVFGERASPLPFAGPRRHQPPGLSLAQLPHIDLVLLSH 130 Query: 155 GHYDHLDVATLSRLAGAFGS--RVITPLGNDVTM-------RTSDAAIKAEAFDWHQRIE 205 HYDHL A++ L G PLG D R S + AFDW Sbjct: 131 NHYDHLCRASVRALMRQPGGAPMFFVPLGIDRWFKRHVRGTRLSGEHVNVRAFDWDTEAR 190 Query: 206 LGNGLAATLVPTRHWSARGLFDRNKALWASFVLETPAGKLYIVGDSGYGDGGHFRRVAEA 265 G + +HWSARGL+DRN+ LW S+ L P + + GD GY R + Sbjct: 191 FGP-FSVHFCAVQHWSARGLYDRNRTLWGSWALLHPQLRFWFSGDLGYSQDT--RDIGAR 247 Query: 266 HGPLRLAILPIGAYEPRWFMRDQHMNPEDAVKALADCGAAQALAHHHGTFQLTDEAIDAP 325 G +A + +GAYEPRWFM+ QH++P +AV+ + D GA A+ H GTF LTDE +D P Sbjct: 248 FGHFDVAAIAVGAYEPRWFMKTQHIDPAEAVQVMQDIGARHAVGIHWGTFPLTDEPLDQP 307