BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0040.0012.p (262 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll3632 [IQR] COG1028 Dehydrogenases with different specificitie... 383 e-106 SMb21010 [IQR] COG1028 Dehydrogenases with different specificiti... 341 1e-93 CC3384 [IQR] COG1028 Dehydrogenases with different specificities... 317 2e-86 AGc4198 [IQR] COG1028 Dehydrogenases with different specificitie... 316 4e-86 BMEI0268 [IQR] COG1028 Dehydrogenases with different specificiti... 305 5e-83 >mll3632 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 262 Score = 383 bits (983), Expect = e-106, Method: Compositional matrix adjust. Identities = 188/262 (71%), Positives = 217/262 (82%) Query: 1 MGTLTGKTAVVTGSTSGIGLAYARAFAGAGANIVLNGMGVPADIEKERSGIETDFKVKAV 60 MG+L+ K A+VTGSTSGIGLA ARAFA GAN+ +NG+G PA IE+ER+GIE DF VK Sbjct: 1 MGSLSSKNALVTGSTSGIGLAIARAFAAEGANVTINGLGDPAAIEQERAGIEKDFGVKCR 60 Query: 61 HSPADMTKPAEIADMIALGEKTFGSVDILVNNAGIQFVSPIEEFPPEKWEAIIAINLSSA 120 +S A+M A ++ M+ E FGS+DILVNNAGIQ V+PIEEFP +KWEAII INL +A Sbjct: 61 YSDANMMDGAAVSAMVHDAEAAFGSLDILVNNAGIQHVAPIEEFPDDKWEAIIRINLLAA 120 Query: 121 FYGIRAAVPGMKKRGWGRIINTASAHSLVASPFKSAYVSAKHGIAGLTKTVALELAQHKI 180 FY I+AAVPGMK R WGRIINTASAH+LVASPFKSAYVSAKHGIAGLTKTVALE+AQ I Sbjct: 121 FYAIKAAVPGMKARKWGRIINTASAHALVASPFKSAYVSAKHGIAGLTKTVALEVAQDGI 180 Query: 181 TCNCISPGYVWTPLVEHQIPETMKARNMTKEQVIKDVLLAAQPTKEFVTSDQVAALALFL 240 T N I+PGYVWTPLVE QIP+TMKAR MT+EQV DVLLAAQPTKEFVT +++AAL LFL Sbjct: 181 TVNAIAPGYVWTPLVEKQIPDTMKARGMTEEQVKHDVLLAAQPTKEFVTVEELAALTLFL 240 Query: 241 CSDDAAQITGSNYSIDGGWTAE 262 CSD A QITG+ +DGGWTA+ Sbjct: 241 CSDAARQITGTTLPMDGGWTAQ 262 >SMb21010 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 258 Score = 341 bits (874), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 167/259 (64%), Positives = 204/259 (78%), Gaps = 6/259 (2%) Query: 7 KTAVVTGSTSGIGLAYARAFAGAGANIVLNGMGVPADIE---KERSGIETDFKVKAVHSP 63 KTAV+TGSTSGIGLA AR A AGANIVLNG G P +I E +G+ + +H P Sbjct: 3 KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSG---TVLHHP 59 Query: 64 ADMTKPAEIADMIALGEKTFGSVDILVNNAGIQFVSPIEEFPPEKWEAIIAINLSSAFYG 123 ADMTKP+EIADM+A+ FG DILVNNAG+QFV IE+FP E+W+ IIA+NLSS+F+ Sbjct: 60 ADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHT 119 Query: 124 IRAAVPGMKKRGWGRIINTASAHSLVASPFKSAYVSAKHGIAGLTKTVALELAQHKITCN 183 IR A+P MKK+GWGRIIN ASAH LVASPFKSAYV+AKHGI GLTKTVALE+A+ +T N Sbjct: 120 IRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTVN 179 Query: 184 CISPGYVWTPLVEHQIPETMKARNMTKEQVIKDVLLAAQPTKEFVTSDQVAALALFLCSD 243 I PGYV TPLVE QIP+ + R +T+EQVI +V+L QPTK+F+T +QVA+LAL+L D Sbjct: 180 SICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLAGD 239 Query: 244 DAAQITGSNYSIDGGWTAE 262 DAAQITG++ S+DGGWTA+ Sbjct: 240 DAAQITGTHVSMDGGWTAQ 258 >CC3384 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 265 Score = 317 bits (812), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 153/259 (59%), Positives = 196/259 (75%) Query: 4 LTGKTAVVTGSTSGIGLAYARAFAGAGANIVLNGMGVPADIEKERSGIETDFKVKAVHSP 63 L G+ A+VTGSTSGIG A A A A G NIV+NG+G IE+ R+ + V+ ++ Sbjct: 7 LQGQVAIVTGSTSGIGHAMADALAAQGCNIVMNGLGEMNAIERARAEMAETHGVEVLYHG 66 Query: 64 ADMTKPAEIADMIALGEKTFGSVDILVNNAGIQFVSPIEEFPPEKWEAIIAINLSSAFYG 123 ADMT+P EIADM+ + FG +DILVNNAG+Q V+P+E+FP +KW+ IIA+NLSSAF+ Sbjct: 67 ADMTRPIEIADMVRAAKAEFGELDILVNNAGVQHVAPVEDFPEDKWDLIIAVNLSSAFHA 126 Query: 124 IRAAVPGMKKRGWGRIINTASAHSLVASPFKSAYVSAKHGIAGLTKTVALELAQHKITCN 183 +AAVP MK++G GRI+N ASAH LVASPFKSAYV+AKHGI GLTKTVALE+AQH ITCN Sbjct: 127 TKAAVPIMKEQGRGRIVNIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAQHGITCN 186 Query: 184 CISPGYVWTPLVEHQIPETMKARNMTKEQVIKDVLLAAQPTKEFVTSDQVAALALFLCSD 243 I PG+V TPLVE QI + KAR +++E V++DV+LA+QPTK+FVT DQ+ + L+L SD Sbjct: 187 AICPGFVKTPLVEAQIADQAKARGISEEAVMRDVILASQPTKQFVTFDQLNGMLLYLVSD 246 Query: 244 DAAQITGSNYSIDGGWTAE 262 A G+ Y IDGGW A+ Sbjct: 247 LGASANGAAYQIDGGWVAQ 265 >AGc4198 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 305 Score = 316 bits (809), Expect = 4e-86, Method: Compositional matrix adjust. Identities = 159/256 (62%), Positives = 194/256 (75%) Query: 7 KTAVVTGSTSGIGLAYARAFAGAGANIVLNGMGVPADIEKERSGIETDFKVKAVHSPADM 66 +T +VTGSTSGIGL A+ FA GANIVLNG G +IEK R +E + + ++ PADM Sbjct: 50 RTVIVTGSTSGIGLGIAQRFAREGANIVLNGFGDDDEIEKLRLLLEAESGGRVLYHPADM 109 Query: 67 TKPAEIADMIALGEKTFGSVDILVNNAGIQFVSPIEEFPPEKWEAIIAINLSSAFYGIRA 126 TKP EIAD+I + GSVD+L+NNAGIQ ++PIEEFP EKW+ IIAINL+S+F+ +RA Sbjct: 110 TKPDEIADLIQSSHEKLGSVDVLINNAGIQHIAPIEEFPTEKWDWIIAINLTSSFHTMRA 169 Query: 127 AVPGMKKRGWGRIINTASAHSLVASPFKSAYVSAKHGIAGLTKTVALELAQHKITCNCIS 186 A+P MKK G GRIIN +SAH LVASPFKSAYV+AKHGI GLTKT ALELAQ +T N I Sbjct: 170 AIPLMKKAGKGRIINISSAHGLVASPFKSAYVAAKHGIMGLTKTAALELAQTGVTVNAIC 229 Query: 187 PGYVWTPLVEHQIPETMKARNMTKEQVIKDVLLAAQPTKEFVTSDQVAALALFLCSDDAA 246 PGYV TPLVE QIPE K R +++ V DV+L Q TK+FVT D VAA A+FL SD A+ Sbjct: 230 PGYVLTPLVEKQIPEMAKVRGISEAAVKNDVMLELQATKQFVTVDDVAAAAIFLASDAAS 289 Query: 247 QITGSNYSIDGGWTAE 262 ITG++ S+DGGWTA+ Sbjct: 290 NITGTHISVDGGWTAQ 305 >BMEI0268 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bme Brucella melitensis Length = 271 Score = 305 bits (782), Expect = 5e-83, Method: Compositional matrix adjust. Identities = 153/256 (59%), Positives = 186/256 (72%) Query: 7 KTAVVTGSTSGIGLAYARAFAGAGANIVLNGMGVPADIEKERSGIETDFKVKAVHSPADM 66 KTA+VTGS SGIGL A A A AG N+V+N + + + ++ ADM Sbjct: 16 KTAIVTGSNSGIGLGIAHALAAAGHNVVINSFTDRDEDHALARMLAEEHGANVIYIAADM 75 Query: 67 TKPAEIADMIALGEKTFGSVDILVNNAGIQFVSPIEEFPPEKWEAIIAINLSSAFYGIRA 126 +K + ++IA K FG+ DILVNNAGIQ V+P+EEFPPE+W+ IIAINL+SAF+ A Sbjct: 76 SKAEDCRNLIAKTVKVFGNSDILVNNAGIQHVAPVEEFPPEQWDRIIAINLTSAFHTSAA 135 Query: 127 AVPGMKKRGWGRIINTASAHSLVASPFKSAYVSAKHGIAGLTKTVALELAQHKITCNCIS 186 A+P M+K GWGRIIN ASAH LVASPFKSAYV+AKHGI G TKT+ALELA KIT N I Sbjct: 136 AIPHMRKAGWGRIINIASAHGLVASPFKSAYVAAKHGIVGFTKTLALELATAKITANSIC 195 Query: 187 PGYVWTPLVEHQIPETMKARNMTKEQVIKDVLLAAQPTKEFVTSDQVAALALFLCSDDAA 246 PGYV TPLVE QIP+ MKA +M +E VI+DV+L QPTKEFVT+ Q+ A+A FL SD AA Sbjct: 196 PGYVLTPLVEAQIPDQMKAHHMDRETVIRDVMLDKQPTKEFVTTAQIGAVATFLASDAAA 255 Query: 247 QITGSNYSIDGGWTAE 262 QI G+ S+DGGWTAE Sbjct: 256 QINGAAISVDGGWTAE 271