BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0039.0002.p (418 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC3460 Non COG 401 e-111 PAB0090 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Pab... 101 3e-21 RSp1187 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Rso... 92 2e-18 Rv2913c [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Mtu... 92 3e-18 MT2981 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase MtC ... 92 3e-18 >CC3460 Non COG Length = 581 Score = 401 bits (1031), Expect = e-111, Method: Compositional matrix adjust. Identities = 213/376 (56%), Positives = 263/376 (69%), Gaps = 4/376 (1%) Query: 6 DLVIRGGTIADGKGGDLYEADVAISGGKITEVGKVSAKGTEEIDAKGKLVAPGFVDVHTH 65 DLV+R G + DG GG ++ADV + G I VGK A G EEIDA+G++V PGFVD+HTH Sbjct: 7 DLVLRSGVVFDGAGGPGFQADVGVRDGVIVAVGKGLAAGAEEIDARGRIVTPGFVDIHTH 66 Query: 66 YDGQVTWSQDITPSSQNGVTTAIMGNCGVGFAPCRPSDHTRLIQLMEGVEDIPEPVLSAG 125 YDGQ TWS + PSS +GVTT +MGNCGVGFAPCRP DH RLI+LMEGVEDIP PVL+ G Sbjct: 67 YDGQATWSGQLGPSSGHGVTTVVMGNCGVGFAPCRPDDHDRLIRLMEGVEDIPFPVLTEG 126 Query: 126 IPWAWESFPDYMEWLSKRSFDMDVGAQLPHAALRVYVMGERGARRDPATPDDNKAMAALA 185 +PWAWESFPDY+++L+ R+FD+DVGAQLPHAALRVYVMG+RGA R+PAT D AMAA+A Sbjct: 127 LPWAWESFPDYLDFLAGRAFDVDVGAQLPHAALRVYVMGDRGADREPATDADIAAMAAIA 186 Query: 186 GDAVRAGALGFSTSRTLNHRTSTGDYTPTLKAGEDELTAIAGAMHGVGRSVLQFVLDQST 245 AV AGALGFSTSRTLNHRTS G TPTL AGEDELT IA + G+ VLQ V D Sbjct: 187 RRAVEAGALGFSTSRTLNHRTSDGQPTPTLTAGEDELTGIALGLAAAGKGVLQVVSDFVD 246 Query: 246 VHEDLPMMLRVAENTRCPISFSVAQADKAPRRWRQTMDTINEAAARGLSITTQIAARPVG 305 +L M+ R+ E + P+SFS+ Q+ KAP WR +D + A GL + Q+ RPVG Sbjct: 247 GAAELAMLRRIVERSGRPLSFSLVQSPKAPEGWRGLLDGVAAAVDAGLPMKAQVCGRPVG 306 Query: 306 LLLGLELSRNPFQTHPSYREIARLPLAERLAQLRRPEVRAAILSESATATDDPLFFRP-- 363 +L GLEL+ NPF +P + E+ PLA+++A L P RA +L+ A P Sbjct: 307 VLFGLELTLNPFSQNPVFAELKDRPLADKVAALSDPAFRARLLAHDGDAR-GPFAGSALR 365 Query: 364 NYDKMYLLGN-PPDYE 378 +D +Y +G PDYE Sbjct: 366 AWDNLYPMGGVDPDYE 381 >PAB0090 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Pab Pyrococcus abyssi Length = 526 Score = 101 bits (252), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 80/298 (26%), Positives = 131/298 (43%), Gaps = 24/298 (8%) Query: 6 DLVIRGGTIADGKGGDLYEADVAISGGKITEVGKVSAKGTEEIDAKGKLVAPGFVDVHTH 65 D+VI+ G I DG G + D+ I GKI ++GK+ G IDA +VAPGF+D+H H Sbjct: 5 DIVIKNGKIVDGTGNPWFRTDIGIKDGKIVKIGKIKEDGQVTIDASNLIVAPGFIDMHAH 64 Query: 66 YDGQVTWSQDITPSSQNGVTTAIMGNCGVGFAPCRPSDHTRLIQLMEGVEDIPEPVLSAG 125 D + GVTT + GNCG+ AP + ++ +++ I L Sbjct: 65 DDLIFFKDRFNRAKLLQGVTTVVSGNCGISVAPV----NEEMLDVLKSYVGI----LGKE 116 Query: 126 IPWAWESFPDYMEWLSKRS-FDMDVGAQLPHAALRVYVMGERGARRDPATPDDNKAMAAL 184 + + W S+ ++++ L + + + H LR+ VMG RDP T ++ M L Sbjct: 117 VEFKWRSYGEFLDALEEVGPLGTNFVGLVGHGTLRIAVMGMEA--RDP-TEEELGRMKEL 173 Query: 185 AGDAVRAGALGFSTSRTLNHRTSTGDYTPTLKAGEDELTAIAGAMHGVGRSVLQFVLDQS 244 ++ GA G S+ Y P + + EL +A + G + D+ Sbjct: 174 LAKSMEEGAFGMSSGLI---------YPPGVYSKTWELIELAMVVAKYGGIYSTHMRDEG 224 Query: 245 T-VHEDLPMMLRVAENT--RCPISFSVAQADKAPRRWRQTMDTINEAAARGLSITTQI 299 V E L +R+ + R +S K + R+T+ I +A G+ IT + Sbjct: 225 NRVIEALEEAIRIGRESGVRVEVSHHKVSGRKNWGKSRKTLALIEKARNEGIEITLDV 282 >RSp1187 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Rso Ralstonia solanacearum Length = 494 Score = 92.4 bits (228), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 83/269 (30%), Positives = 129/269 (47%), Gaps = 30/269 (11%) Query: 6 DLVIRGGTIADGKGGD----LYEADVAISGGKITEVGKVSAK---GTEEIDAKGKLVAPG 58 D VIR I DG G + L+ DVAI+ G+I + + G EE+D G+++APG Sbjct: 5 DSVIRRVRIVDGSGHEPESTLF--DVAIADGRIAAIATSDSTAWLGDEEVDGAGRVLAPG 62 Query: 59 FVDVHTHYDGQVTWSQDITPSSQNGVTTAIMGNCGVGFAPCRPSDHTRLIQLMEGVEDIP 118 F+DVHTH D V + D+ P G+TT I+GNCG+ +P + G P Sbjct: 63 FIDVHTHDDTNVIRTPDMLPKVSQGITTVIVGNCGISASPA----------TLRGEPPDP 112 Query: 119 EPVLSAGIPWAWESFPDYMEWLSKRSFDMDVGAQLPHAALRVYVMGERGARRDPATPDDN 178 +L + + +F Y+E + + ++V A + H ALR + +R R PAT + Sbjct: 113 MNLLGPAGAFRYPTFASYVEAVEQARPAVNVAALVGHTALRNNHL-DRLDR--PATAPEV 169 Query: 179 KAMAALAGDAVRAGALGFSTSRTLNHRTSTGDYTPTLKAGEDELTAIAGAMHGVGRSVLQ 238 +AM A +A+ GALG ST L + + T + + + L A AGA++ Sbjct: 170 EAMRAQLREALDHGALGLSTG--LAYANAHAAATEEVMSLAEPL-AEAGALY-----TTH 221 Query: 239 FVLDQSTVHEDLPMMLRVAENTRCPISFS 267 + + + E + RV + R PI S Sbjct: 222 LRTEFAAILEAMDEAYRVGRHARVPIVIS 250 >Rv2913c [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase Mtu Mycobacterium tuberculosis H37Rv Length = 611 Score = 92.0 bits (227), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 66/203 (32%), Positives = 95/203 (46%), Gaps = 10/203 (4%) Query: 2 TSTPDLVIRGGTIADGKGGDLYEADVAISGGKITEV--GKVSAKGT-EEIDAKGKLVAPG 58 T T D++IR G DG G + I G + V G + G E +DA GK V PG Sbjct: 13 TVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAAGALDETGCPEVVDAAGKWVVPG 72 Query: 59 FVDVHTHYDGQVTWSQDITPSSQNGVTTAIMGNCGVGFAPCRPSDHTRLIQLMEGVEDIP 118 F+DVHTHYD +V + S ++GVTT ++GNC + D L VE +P Sbjct: 73 FIDVHTHYDAEVLLDPGLRESVRHGVTTVLLGNCSLSTVYANSEDAA---DLFSRVEAVP 129 Query: 119 EPVLSAGI--PWAWESFPDYMEWLSKRSFDMDVGAQLPHAALRVYVMGERGARRDPATPD 176 + + W + +Y+E + +V + L H+ LR V+G A D P Sbjct: 130 REFVLGALRDNQTWSTPAEYIEAIDALPLGPNVSSLLGHSDLRTAVLGLDRATDDTVRPT 189 Query: 177 DNK--AMAALAGDAVRAGALGFS 197 + + MA L +A+ AG LG S Sbjct: 190 EAELAKMAKLLDEALEAGMLGMS 212 >MT2981 [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase MtC Mycobacterium tuberculosis CDC1551 Length = 611 Score = 92.0 bits (227), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 66/203 (32%), Positives = 95/203 (46%), Gaps = 10/203 (4%) Query: 2 TSTPDLVIRGGTIADGKGGDLYEADVAISGGKITEV--GKVSAKGT-EEIDAKGKLVAPG 58 T T D++IR G DG G + I G + V G + G E +DA GK V PG Sbjct: 13 TVTYDVIIRDGLWFDGTGNAPLTRTLGIRDGVVATVAAGALDETGCPEVVDAAGKWVVPG 72 Query: 59 FVDVHTHYDGQVTWSQDITPSSQNGVTTAIMGNCGVGFAPCRPSDHTRLIQLMEGVEDIP 118 F+DVHTHYD +V + S ++GVTT ++GNC + D L VE +P Sbjct: 73 FIDVHTHYDAEVLLDPGLRESVRHGVTTVLLGNCSLSTVYANSEDAA---DLFSRVEAVP 129 Query: 119 EPVLSAGI--PWAWESFPDYMEWLSKRSFDMDVGAQLPHAALRVYVMGERGARRDPATPD 176 + + W + +Y+E + +V + L H+ LR V+G A D P Sbjct: 130 REFVLGALRDNQTWSTPAEYIEAIDALPLGPNVSSLLGHSDLRTAVLGLDRATDDTVRPT 189 Query: 177 DNK--AMAALAGDAVRAGALGFS 197 + + MA L +A+ AG LG S Sbjct: 190 EAELAKMAKLLDEALEAGMLGMS 212