BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0038.0028.p (1338 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value DR2267 [V] COG1002 Type II restriction enzyme, methylase subunit... 170 2e-41 DRA0119.1 [V] COG1002 Type II restriction enzyme, methylase subu... 145 7e-34 CC0826 [V] COG1002 Type II restriction enzyme, methylase subunit... 136 3e-31 VNG6135C [V] COG1002 Type II restriction enzyme, methylase subun... 129 5e-29 VNG7096 [V] COG1002 Type II restriction enzyme, methylase subuni... 129 6e-29 >DR2267 [V] COG1002 Type II restriction enzyme, methylase subunits Dra Deinococcus radiodurans Length = 840 Score = 170 bits (431), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 127/444 (28%), Positives = 205/444 (46%), Gaps = 58/444 (13%) Query: 795 GGKLDRVSLSIDVENAIKEGQTLGLHNRTIQGLTKGLDTGKPPRRPFHWPLE-FPEVFVR 853 G +L +V+L++ E AI+E L L N GLD +P PL+ + V+ Sbjct: 411 GVELAKVTLTLAKELAIREMHDL-LGN-------TGLDFDQP------LPLDNLDDRIVQ 456 Query: 854 ED------PGFDAIVGNPPFVTGKRISTHLTEEYQTYLKQTFAQSKGAADLCVFFLRRAF 907 D P DAIVGNPPF + ++ + Y L+ + G AD CV+++R+A Sbjct: 457 GDALFTPWPRVDAIVGNPPFQSKNKLQREMGAAYVKKLRAHYPDVPGRADYCVYWIRKAH 516 Query: 908 DLIRAEAQVGMIGTKSIAEGDSRLVGVKYLLDSGGRVIWAIHELPWPGKASVTVSLLVIR 967 D + + + G++GT +I + DSR+ G+ Y++ GG + A+ W G A+V VS++ Sbjct: 517 DQLGSGQRAGLVGTNTIRQNDSRVGGLDYVVQHGGTITDAVGTQVWSGDAAVHVSIVNWV 576 Query: 968 KGSWAAPLLLNGRRVDS------------ISNRLTSDS-IAEVSKL--DGNKGLCSDGIK 1012 KG P L + D I++ L++ + + + KL + N G C G Sbjct: 577 KGPAEGPKHLAWQVGDHRTSPWQSTELPVINSALSAGTDVTQAQKLRVNMNSGACYQGQT 636 Query: 1013 IQGDGFVVSDQERTALLAADTRNDDVLRPYITGIDITQGVNAQPASWIINFAKRTEAEAS 1072 GF++ E +L+A+ +N +V+ PY+TG ++ + P ++I+F R A Sbjct: 637 HGHKGFLLDGLEAGQMLSAERKNAEVIFPYLTGDELLRTSPPHPTRYVIDFQPRDVFGAR 696 Query: 1073 AYPAPMRILQERVKPYRDTLTGQI------------------HEHDF----WKFWDKREA 1110 AY P ++ V P R + H +F W R Sbjct: 697 AYKLPFARIEREVLPTRQAAAAEEEARNAEVLAANPKAKTNKHHRNFLNQWWALSYGRSE 756 Query: 1111 FFERMKNAKRILACPSTAKFLILTFIDPSWIPSHSVKLFAFEDFGSFALLQSSVHECWVR 1170 E++ + R + C K + F+D PS +++FAFED SF ++QSSVH W+ Sbjct: 757 MIEKISSLSRYIVCSRVTKRQVFEFLDNGIRPSDGLQIFAFEDDYSFGVIQSSVHWQWLI 816 Query: 1171 LQSGKLEQRLAYNLSKGFATFPFP 1194 + G L RL Y F TFP+P Sbjct: 817 ARGGTLTARLMYTSDTVFDTFPWP 840 >DRA0119.1 [V] COG1002 Type II restriction enzyme, methylase subunits Dra Deinococcus radiodurans Length = 671 Score = 145 bits (366), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 121/423 (28%), Positives = 192/423 (45%), Gaps = 25/423 (5%) Query: 856 PGFDAIVGNPPFVTGKRISTHLTEEYQTYLKQTFAQS-KGAADLCVFFLRRAFDLIRA-- 912 P D IVGNPPF+ K + + L E Y T L++TF G +DL ++ +A LI A Sbjct: 233 PRADFIVGNPPFLGDKMMRSQLGEAYTTQLRETFKDRLPGQSDLVCYWPEKARALIEAGV 292 Query: 913 EAQVGMIGTKSIAEGDSRLVGVKYLLDSGGRVIWAIHELPWP-GKASVTVSLLVIRKGSW 971 + G + T SI G +R+V + + + G + A + PW A+V VSL G+ Sbjct: 293 TTRAGFVTTNSIRGGKNRVVLER--IKATGDLFMAWPDEPWQQNGAAVRVSLFGFDNGT- 349 Query: 972 AAPLLLNGRRVDSISNRLTSDS-IAEVSKLDGNKGLCSDGIKIQGDGFVVSDQERTALLA 1030 LN V I+ L + + + + KL N G+ G + G + D R+ L Sbjct: 350 ETLRTLNDGHVGVINADLNAGTDVKQAQKLPENAGVSFIGTQKGGAFDIPGDLARSWLSV 409 Query: 1031 AD---TRNDDVLRPYITGIDITQGVNAQPASWIINFAKRTEAEASAYPAPMRILQERVKP 1087 + N DVL+P++ G+D+T+ + + WII+FA+ E EA Y PM ++++++P Sbjct: 410 PNPDRVSNADVLKPWVNGMDLTRRPSGR---WIIDFAQMDEGEARQYLQPMAYVEQKIRP 466 Query: 1088 YRDTLTGQIHEHDFWKFWDKREAFFERMKNAKRILACPSTAKFLILTFIDPSWIPSHSVK 1147 R T + + +W R E R + P AK L+ ++ +P V Sbjct: 467 ERATNSDRPSRERWWLHQRSRPELREATIELDRFIGIPRVAKHLLPVWLPEGTLPDSQVV 526 Query: 1148 LFAFEDFGSFALLQSSVHECWVRLQSGKL--EQRLAYNLSKGFATFPFP----EQAANAD 1201 + A +D F +L S++H W R+Q + L Y S F TFP P EQ A + Sbjct: 527 VIARDDDFIFGVLASTIHRSWARMQGTYMGVGNDLRYTPSTCFETFPVPAPTDEQRAEIE 586 Query: 1202 LGEQLYFQRREICRNRGL--CLTDLYNMVHDKNERSDDIIRLRELIAQNDA---EISALY 1256 + Q RE N+ LT +YN + D + L +D ++ Y Sbjct: 587 KWAKYIVQLREHLLNQDAKGTLTGIYNQLEKLRNSPDAAHPVSALATAHDKLDQAVATAY 646 Query: 1257 GWQ 1259 GW+ Sbjct: 647 GWE 649 >CC0826 [V] COG1002 Type II restriction enzyme, methylase subunits Ccr Caulobacter vibrioides Length = 985 Score = 136 bits (343), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 103/355 (29%), Positives = 175/355 (49%), Gaps = 24/355 (6%) Query: 856 PGFDAIVGNPPFVTGKRISTHLTEEYQTYLKQTF-AQSKGAADLCVFFLRRAFDLIRAEA 914 P D IVGNPPF+ KR+ L +Y L T+ + AD +++ +A++L++A+ Sbjct: 516 PAVDVIVGNPPFLGSKRLRDGLGNDYVERLFSTYRGKVPAEADFVAYWIAKAWELVQAQQ 575 Query: 915 --QVGMIGTKSIAEGDSRLVGVKYLLDSGGRVIWAIHELPWPGK-ASVTVSLLVIRKGSW 971 + G++ T S+ G SR V + + D+G ++ A + PW + A+V VS+ G Sbjct: 576 GRRAGLVTTNSVRGGASRKV-LDPIADAGA-LMEAWADEPWALEGAAVRVSMFGFGDGF- 632 Query: 972 AAPLLLNGRRVDSISN--RLTSDSIAEVSKLDGNKGLCSDGIKIQGDGFVVSDQ-----E 1024 A L GR+ + + + R S + + +L N + G +G F VS + Sbjct: 633 -AERRLEGRKAEHLHSDFRGASTDVTKALRLKENASIAFMG-DTKGGAFDVSGEIAREWL 690 Query: 1025 RTALLAADTRNDDVLRPYITGIDITQGVNAQPASWIINFA-KRTEAEASAYPAPMRILQE 1083 R L N DVL+P+ +D+T+ + + WII+F +EA+A+ + P R + Sbjct: 691 RLPLNPNGRPNSDVLKPWRNAMDMTRRSSDK---WIIDFGWTMSEADAALFETPFRHVLL 747 Query: 1084 RVKPYRDTLTGQIHEHDFWKFWDKREAFFERMKNAKRILACPSTAKFLILTFIDPSWIPS 1143 VKP RD +++ ++WK + R+ +R+ R+L P +K + ++D +P Sbjct: 748 HVKPERDRNNREMYRLNWWKHVEPRQGLMKRVPALSRLLVTPEVSKHRLFIWLDARVLPD 807 Query: 1144 HSVKLFAFEDFGSFALLQSSVHECWVRLQSGKLE---QRLAYNLSKGFATFPFPE 1195 H +++ +D SF +L S HE W L +G Y +S F TFPFPE Sbjct: 808 HKLQVVTLDDDCSFGVLHSRFHEVWA-LAAGSWHGSGNDPRYTISTTFETFPFPE 861 >VNG6135C [V] COG1002 Type II restriction enzyme, methylase subunits Hbs Halobacterium sp. NRC-1 Length = 662 Score = 129 bits (324), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 87/251 (34%), Positives = 136/251 (54%), Gaps = 30/251 (11%) Query: 529 LVYPKHTFMVTMGSNRRETGTHYTPKALTESIVTETLEPLV---YSGLAEGKAR---QKW 582 +V ++ T R+ TG++YTP+ + E IV TLEPLV + LA AR + + Sbjct: 420 VVQEGEVYLTTDSGERKATGSYYTPEYVVEYIVENTLEPLVDDIRADLAGRSARGEDRGF 479 Query: 583 KLKTPSELLDLKICDPAMGSGAFLVQVCRWLSERLVEAWA-EAEKQGNAISSEGEVLRAI 641 + + DLKI DPAMGSG FL +L+ +++A +A +QG Sbjct: 480 AEEFAERIFDLKILDPAMGSGHFLTSAIDYLAREIIDAQERQAAQQG------------- 526 Query: 642 GSREPLRNDPEERLVTARRLIAERCLYGVDLNPMAVELAKLSIWLVTLAKGRPFGFLDHN 701 E + D + + ARR +A+RC+YGVDLNP+AVELAK+S+WL TLA +P FLDH+ Sbjct: 527 --IETVNQDHD--INWARRQVAQRCIYGVDLNPLAVELAKVSLWLRTLAAEQPLAFLDHH 582 Query: 702 LRIGDSLLGVHDLEQLYHLE----PKAHSTDSQSL-FAANIDAAVHRAIDVRISLRDRPI 756 L+ G+SL+G ++E++ LE +A +S + F + + + + L Sbjct: 583 LKTGNSLVG-SNVEEIDALERNGAAEAEGPNSTLIDFGMTFEGTMENLMAIHADLIAIEN 641 Query: 757 RDIRDVEAMSR 767 ++ DV+AM + Sbjct: 642 EELEDVKAMEK 652 >VNG7096 [V] COG1002 Type II restriction enzyme, methylase subunits Hbs Halobacterium sp. NRC-1 Length = 706 Score = 129 bits (323), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 87/251 (34%), Positives = 136/251 (54%), Gaps = 30/251 (11%) Query: 529 LVYPKHTFMVTMGSNRRETGTHYTPKALTESIVTETLEPLV---YSGLAEGKAR---QKW 582 +V ++ T R+ TG++YTP+ + E IV TLEPLV + LA AR + + Sbjct: 464 VVQEGEVYLTTDSGERKATGSYYTPEYVVEYIVENTLEPLVDDIRADLAGRSARGEDRGF 523 Query: 583 KLKTPSELLDLKICDPAMGSGAFLVQVCRWLSERLVEAWA-EAEKQGNAISSEGEVLRAI 641 + + DLKI DPAMGSG FL +L+ +++A +A +QG Sbjct: 524 AEEFAERIFDLKILDPAMGSGHFLTSAIDYLAREIIDAQERQAAQQG------------- 570 Query: 642 GSREPLRNDPEERLVTARRLIAERCLYGVDLNPMAVELAKLSIWLVTLAKGRPFGFLDHN 701 E + D + + ARR +A+RC+YGVDLNP+AVELAK+S+WL TLA +P FLDH+ Sbjct: 571 --IETVNQDHD--INWARRQVAQRCIYGVDLNPLAVELAKVSLWLRTLAAEQPLAFLDHH 626 Query: 702 LRIGDSLLGVHDLEQLYHLE----PKAHSTDSQSL-FAANIDAAVHRAIDVRISLRDRPI 756 L+ G+SL+G ++E++ LE +A +S + F + + + + L Sbjct: 627 LKTGNSLVG-SNVEEIDALERNGAAEAEGPNSTLIDFGMTFEGTMENLMAIHADLIAIEN 685 Query: 757 RDIRDVEAMSR 767 ++ DV+AM + Sbjct: 686 EELEDVKAMEK 696