BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0003.p (365 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0820 [K] COG0583 Transcriptional regulator Bme Brucella mel... 215 1e-55 DRA0336 [K] COG0583 Transcriptional regulator Dra Deinococcus ra... 200 5e-51 STM3121 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 189 1e-47 PA5029 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 179 8e-45 YPO1929 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 170 4e-42 >BMEII0820 [K] COG0583 Transcriptional regulator Bme Brucella melitensis Length = 299 Score = 215 bits (548), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 123/234 (52%), Positives = 155/234 (66%), Gaps = 5/234 (2%) Query: 3 MDCLPMIELRHLRYAVAVAEEGHITRAAARLGIQQPPLSQQIRALETAIGAPLFRRQPRG 62 MD +PM ELRHLRY +AVAEEG+ TRAAA+LGI QPPLSQQIR LE IG LF R P G Sbjct: 1 MD-IPM-ELRHLRYFLAVAEEGNFTRAAAKLGIGQPPLSQQIRDLENEIGVMLFHRVPHG 58 Query: 63 VELTAAGRAFVGKARAILRDAELAVEAARRASRGQEGQLAIGFTSSAAFHPFVTGVMREM 122 ELTAAG AF+ +A A + +E A AA+RA+RG+ G+L++GFT+S+AF+P V+G +R Sbjct: 59 AELTAAGAAFLEEATATIASSEKAKLAAQRAARGESGRLSLGFTASSAFNPIVSGAIRHF 118 Query: 123 RERAPAITLSLEEASTGELIAAVEADRLDAAFVRAPSERLENLTITHLLDEEMVVALPDH 182 R + P + L L E +T LI + LD AF+R E N+ + L DE M+VALP H Sbjct: 119 RAKWPEVELFLTEMNTNLLIERLVRGELDTAFIRPGLEDPANVRMKRLADEPMLVALPSH 178 Query: 183 HPRARKDTRRRISLASLADEPLILYRRPTGPGLYDSIIAACRAAGFSPKVAQEA 236 H R R+ L++LA EP +L+ R G LYD I AACR AGF V QEA Sbjct: 179 H---RLAVYERLPLSALAGEPFVLFPRIVGLSLYDDIAAACRMAGFEMNVTQEA 229 >DRA0336 [K] COG0583 Transcriptional regulator Dra Deinococcus radiodurans Length = 316 Score = 200 bits (508), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 113/232 (48%), Positives = 149/232 (64%), Gaps = 4/232 (1%) Query: 5 CLPMIELRHLRYAVAVAEEGHITRAAARLGIQQPPLSQQIRALETAIGAPLFRRQPRGVE 64 C+PM ELRHLRY +AVA+E ++TRAAARLGIQQPPLSQQIR LE IG PLF R PRGVE Sbjct: 14 CIPM-ELRHLRYFLAVADERNVTRAAARLGIQQPPLSQQIRELEREIGTPLFHRVPRGVE 72 Query: 65 LTAAGRAFVGKARAILRDAELAVEAARRASRGQEGQLAIGFTSSAAFHPFVTGVMREMRE 124 LT AG F+ ++I E A ARRA RG+ G+L +GFT +A+ +P V G++R R+ Sbjct: 73 LTEAGHTFLRLVQSIPAQVEGATHEARRAGRGETGELRVGFTGAASINPQVQGLLRRYRD 132 Query: 125 RAPAITLSLEEASTGELIAAVEADRLDAAFVRAPSERLENLTITHLLDEEMVVALPDHHP 184 P + L+L E +T L+ + + +LDA R + L +LT+T + E MV +P HP Sbjct: 133 LYPDVRLTLTEKNTVTLLDELRSHQLDAVLARPLPQHLGDLTLTLVAREPMVAVVPRGHP 192 Query: 185 RARKDTRRRISLASLADEPLILYRRPTGPGLYDSIIAACRAAGFSPKVAQEA 236 A+ R + L L DE I R GP +YD++ ACRAAGF P++ Q A Sbjct: 193 AAQT---RPLPLERLRDETFITTPREFGPLIYDTVWQACRAAGFEPRLGQLA 241 >STM3121 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 292 Score = 189 bits (479), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 119/286 (41%), Positives = 158/286 (55%), Gaps = 11/286 (3%) Query: 9 IELRHLRYAVAVAEEGHITRAAARLGIQQPPLSQQIRALETAIGAPLFRRQPRGVELTAA 68 +ELRH+RY +AVAEE H TRAA +LGI QPPLSQQI+ LE +GA LFRR P G ELT A Sbjct: 1 MELRHIRYFLAVAEERHFTRAATKLGIGQPPLSQQIKDLERELGAQLFRRVPHGAELTEA 60 Query: 69 GRAFVGKARAILRDAELAVEAARRASRGQEGQLAIGFTSSAAFHPFVTGVMREMRERAPA 128 G+AF + + A AV AA+R +RG+ G L +GFT+SAAF+ V G +R + P Sbjct: 61 GKAFYDVVKGMPATATRAVLAAQRVARGESGVLRVGFTASAAFNSVVPGAIRTFKRAYPD 120 Query: 129 ITLSLEEASTGELIAAVEADRLDAAFVRAPSERLENLTITHLLDEEMVVALPDHHPRARK 188 + L LEE +T +L + LD AF+R E + L +E MV+ L + HP A Sbjct: 121 VRLQLEEGNTTQLADELNEGSLDVAFLRPGFTGNERFQLRLLSEEPMVIVLAETHPAA-- 178 Query: 189 DTRRRISLASLADEPLILYRRPTGPGLYDSIIAACRAAGFSPKVAQ------EATRXRAA 242 ++I+L+ L DE +L+ R G LYD++I AC AGF PK+ Q +A Sbjct: 179 -ACKQIALSILKDEFFLLFPREIGLSLYDAVIKACGKAGFEPKIGQLVPQISSVINLVSA 237 Query: 243 GAGAQEGP--RRRHARPPARDRDAAGEGPRRRLVGTARRSPTSPLL 286 G P R+ R A + P +L RR TSP L Sbjct: 238 EMGVSMVPDSMRQVNVKGVVYRPVADQMPVAKLALAYRRGDTSPTL 283 >PA5029 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 301 Score = 179 bits (454), Expect = 8e-45, Method: Compositional matrix adjust. Identities = 105/229 (45%), Positives = 142/229 (62%), Gaps = 2/229 (0%) Query: 9 IELRHLRYAVAVAEEGHITRAAARLGIQQPPLSQQIRALETAIGAPLFRRQPRGVELTAA 68 +ELRHLRY +AVAEE H RAA RLGI QPPLSQQI+ALE IGA LF R R VELT A Sbjct: 1 MELRHLRYFIAVAEELHFGRAAERLGISQPPLSQQIQALEEEIGARLFERTNRRVELTDA 60 Query: 69 GRAFVGKARAILRDAELAVEAARRASRGQEGQLAIGFTSSAAFHPFVTGVMREMRERAPA 128 GR F+ ++R +L + AV ARRA G+ G+L IGFTSSA F + + R+ P Sbjct: 61 GRLFLDESRQVLAQVDKAVLLARRAHLGELGELKIGFTSSAPFTSTIPSSIHAFRKAYPD 120 Query: 129 ITLSLEEASTGELIAAVEADRLDAAFVRAPSERLENLTITHLLDEEMVVALPDHHPRARK 188 + L L+E S+ +++ A+ + L +R P + + L E +V L HP A Sbjct: 121 VHLDLQEMSSRQVLKALLEESLQVGVIR-PLALPDAVHWVELFREPLVAVLRADHPLA-A 178 Query: 189 DTRRRISLASLADEPLILYRRPTGPGLYDSIIAACRAAGFSPKVAQEAT 237 + +++A+LA+EP + + R G GLYD +IA R AGFSP++AQEA+ Sbjct: 179 GSEDGLAIAALAEEPFVFFPRSYGTGLYDQVIALTRQAGFSPRIAQEAS 227 >YPO1929 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 292 Score = 170 bits (431), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 120/286 (41%), Positives = 158/286 (55%), Gaps = 11/286 (3%) Query: 9 IELRHLRYAVAVAEEGHITRAAARLGIQQPPLSQQIRALETAIGAPLFRRQPRGVELTAA 68 +ELRH+RY +AVAEE H TRAAARLGI QPPLSQQI+ LE +GA LFRR G ELT A Sbjct: 1 MELRHIRYFLAVAEERHFTRAAARLGIGQPPLSQQIKDLERELGALLFRRVSYGAELTEA 60 Query: 69 GRAFVGKARAILRDAELAVEAARRASRGQEGQLAIGFTSSAAFHPFVTGVMREMRERAPA 128 G AF+ + I AE A +AA+RA RG+ G L +GFT+S+AF+ V +R R P Sbjct: 61 GIAFLDVVKEIPVMAERAAQAAQRAVRGELGVLRVGFTASSAFNSVVPTAIRAFRRAYPD 120 Query: 129 ITLSLEEASTGELIAAVEADRLDAAFVRAPSERLENLTITHLLDEEMVVALPDHHPRARK 188 + L LEE +T L + LD AF+R E + L +E M++ + ++HP A Sbjct: 121 VRLQLEEDNTTRLADGLNEGSLDVAFLRPGFAGSERFHLRMLSEEPMMIVMAENHPAASY 180 Query: 189 DTRRRISLASLADEPLILYRRPTGPGLYDSIIAACRAAGFSPKVAQEA------TRXRAA 242 + ISL++ DE +L+ R G LYDS+I +CR AGF P + Q A AA Sbjct: 181 E---EISLSAFRDETFLLFPREIGLTLYDSVIESCRTAGFEPTIGQLAPQIASVINLVAA 237 Query: 243 GAGAQEGP--RRRHARPPARDRDAAGEGPRRRLVGTARRSPTSPLL 286 G P + R A + P +L RR TSP+L Sbjct: 238 EMGVSIVPASMSQVKVIGVVYRHIADQTPTAKLALAYRRGDTSPVL 283