BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0263.p (407 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC3635 [E] COG1171 Threonine dehydratase Ccr Caulobacter vibrioides 366 e-101 TM0356 [E] COG1171 Threonine dehydratase Tma Thermotoga maritima 285 2e-76 Cj0828c [E] COG1171 Threonine dehydratase Cje Campylobacter jejuni 280 3e-75 VNG2100G [E] COG1171 Threonine dehydratase Hbs Halobacterium sp.... 276 9e-74 TVN0190 [E] COG1171 Threonine dehydratase Tvo Thermoplasma volca... 269 7e-72 >CC3635 [E] COG1171 Threonine dehydratase Ccr Caulobacter vibrioides Length = 400 Score = 366 bits (940), Expect = e-101, Method: Compositional matrix adjust. Identities = 208/396 (52%), Positives = 276/396 (69%) Query: 10 ITLADIRRAADVIRDAVMVTACNESRTLGEICGCRLFLKFENLQFTATFKERGALNRLQA 69 + LA I+ AA ++ + T C S+TL +I G +++KFENLQFTA +KERGALN+L Sbjct: 3 LDLAAIQAAAGRLQGQIERTPCRHSKTLSKITGAEVWVKFENLQFTAAYKERGALNKLML 62 Query: 70 LSPEERKRGVIAMSAGNHAQGVAYHAKRLGIPATIVMPIGTPMVKIENTRRHGAEVIITG 129 LS E++RGVIA SAGNHAQG+AYH RLG+P TIVMP TP VK+++TR GA V+I G Sbjct: 63 LSETEKQRGVIAASAGNHAQGLAYHGARLGVPVTIVMPKTTPFVKVQHTRDFGATVVIEG 122 Query: 130 QTLEECFAFVGSHAAQKGLILIHPYDDPLIIAGQGTIGLEMLAAVPELDILVVPIGGGGL 189 +T ++ A ++GL +HP+DD I+AGQGTI LEML P+L+IL VPIGGGGL Sbjct: 123 ETYDDANAHARKLRDEQGLTFVHPFDDYDIMAGQGTIALEMLEDAPDLEILPVPIGGGGL 182 Query: 190 ISGIATAAKALKPSIQVVGVQAQLYPSMYNAVKGEQLPMRGDTLAEGIAVKAPGQITTKI 249 ISG+ATAAKALKP I+++G + +YPS ++G G T+AEG+AVK G++T + Sbjct: 183 ISGVATAAKALKPDIRIIGCEPAMYPSFTAKMRGVAAHCGGQTIAEGVAVKQVGELTYGV 242 Query: 250 VRQLVDDIILVSEDQIERAVATLISIEKTVVEGAGAAGLAAVLAAPARFAGHNVGLVLTG 309 VR L+DD++L+ E +E+AV+ ++EKT+ EGAGAA LAA+LA P RF G GL+L G Sbjct: 243 VRPLLDDVLLLEEPYLEQAVSLYCNVEKTIAEGAGAASLAALLAYPERFRGKKCGLILCG 302 Query: 310 GNIDTRLIASVLTRELAREGRLTQLALDIVDRPGQLAAVSILLADAGANIIEVSHQRTFS 369 GNIDTRL+ASVLTREL R RL L + DRPG L+ V+ ++ GANIIEV+H R Sbjct: 303 GNIDTRLLASVLTRELVRAQRLASLRIIGDDRPGLLSTVASVIGAMGANIIEVNHNRLAL 362 Query: 370 DLPAKATLLELVIETRDRAHLEEVLARLGAEGFAVR 405 D+PAK ++ IETRD H +EV+ L G+ R Sbjct: 363 DVPAKGAEFDITIETRDAQHTQEVMEALRESGYPPR 398 >TM0356 [E] COG1171 Threonine dehydratase Tma Thermotoga maritima Length = 401 Score = 285 bits (728), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 175/398 (43%), Positives = 260/398 (65%), Gaps = 3/398 (0%) Query: 10 ITLADIRRAADVIRDAVMVTACNESRTLGEICGCRLFLKFENLQFTATFKERGALNRLQA 69 ITL DI+ A +++ V TA S L E+ G ++LK ENLQ T +FK RGA N++ Sbjct: 2 ITLEDIKEAQRTLKNVVHRTALAYSSVLSEVTGGEIYLKMENLQKTGSFKIRGAYNKIAH 61 Query: 70 LSPEERKRGVIAMSAGNHAQGVAYHAKRLGIPATIVMPIGTPMVKIENTRRHGAEVIITG 129 LS EERKRGV+A SAGNHAQGVA A+ GIPATIVMP P+ KI TR GA+VI+ G Sbjct: 62 LSEEERKRGVVAASAGNHAQGVALAAQIFGIPATIVMPRYAPLSKITKTRNLGAQVILEG 121 Query: 130 QTLEECFAFVGSHAAQKGLILIHPYDDPLIIAGQGTIGLEMLAAVPELDILVVPIGGGGL 189 +E + + G + +HP++DP +IAGQGTIGLE++ +P+++++VVP+GGGGL Sbjct: 122 NIFDEAYEAALRIQEKTGAVFVHPFNDPHVIAGQGTIGLEIMEDLPDVEVVVVPVGGGGL 181 Query: 190 ISGIATAAKALKPSIQVVGVQAQLYPSMYNAV-KGEQLPMRGD-TLAEGIAVKAPGQITT 247 ISG++ A K++ P ++V+GVQ + PSM ++ +G + G TLA+GIAVK PG +T Sbjct: 182 ISGVSVAIKSMNPEVKVIGVQTENMPSMIASLRRGRAERVEGKPTLADGIAVKKPGDLTF 241 Query: 248 KIVRQLVDDIILVSEDQIERAVATLISIEKTVVEGAGAAGLAAVLAAPARFAGHNVGLVL 307 ++V++ VD+++ V+E++I A+ L+ K V EGAGA G+AAVL G V +V+ Sbjct: 242 ELVKKYVDEMVAVNEEEIADAILFLLEQAKVVAEGAGAVGVAAVL-NKLDVKGKKVAIVI 300 Query: 308 TGGNIDTRLIASVLTRELAREGRLTQLALDIVDRPGQLAAVSILLADAGANIIEVSHQRT 367 +GGNID +I ++ + L + GR + ++DRPG L + ++A+ GAN++ V H R+ Sbjct: 301 SGGNIDVNMIDRIINKGLVKSGRKVFIETFVMDRPGALKELLGIVAELGANVLSVFHNRS 360 Query: 368 FSDLPAKATLLELVIETRDRAHLEEVLARLGAEGFAVR 405 ++P +EL +ET D H+EE+ L A+G+ VR Sbjct: 361 AKEVPIGFAKIELELETVDEKHVEEIERVLIAKGYEVR 398 >Cj0828c [E] COG1171 Threonine dehydratase Cje Campylobacter jejuni Length = 403 Score = 280 bits (717), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 158/401 (39%), Positives = 245/401 (61%), Gaps = 3/401 (0%) Query: 10 ITLADIRRAADVIRDAVMVTACNESRTLGEICGCRLFLKFENLQFTATFKERGALNRLQA 69 + L I +A I V T S L +IC ++LK ENLQ T +K RGA N++ Sbjct: 2 LELNKIYKAKQQISGFVNKTPFIYSSFLSDICQSEIYLKNENLQITGAYKIRGAYNKIAN 61 Query: 70 LSPEERKRGVIAMSAGNHAQGVAYHAKRLGIPATIVMPIGTPMVKIENTRRHGAEVIITG 129 LS E+++ GVIA SAGNHAQGVA AK+ I A IVMP TP++K+ T+ GAEVI+ G Sbjct: 62 LSTEQKQHGVIAASAGNHAQGVAISAKKFSIKAVIVMPESTPLLKVSATKALGAEVILRG 121 Query: 130 QTLEECFAFVGSHAAQKGLILIHPYDDPLIIAGQGTIGLEMLAAVPELDILVVPIGGGGL 189 +E +AF S+A + L IHP++D ++AGQGT+ LEML + +LD+++ P+GGGGL Sbjct: 122 DNFDEAYAFATSYAKENNLSFIHPFEDEFVMAGQGTLMLEMLDEISDLDMIIAPVGGGGL 181 Query: 190 ISGIATAAKALKPSIQVVGVQAQLYPSMYNAVKGEQLPMRGD--TLAEGIAVKAPGQITT 247 ISGI++ AK + P+I+++GV A+ P+MY + +++ T+A+GIAV+ I Sbjct: 182 ISGISSTAKQINPNIKIIGVGAKGAPAMYESFHAKKIKNAKSVRTIADGIAVRDANPINF 241 Query: 248 KIVRQLVDDIILVSEDQIERAVATLISIEKTVVEGAGAAGLAAVLAAPARFAGH-NVGLV 306 I+ + VDD I V +++I AV L+ K +VEGAGAA +AA+L H +G+V Sbjct: 242 NIILECVDDFIQVDDEEIANAVLFLLEKHKIIVEGAGAASVAALLHQKINTQNHKKIGVV 301 Query: 307 LTGGNIDTRLIASVLTRELAREGRLTQLALDIVDRPGQLAAVSILLADAGANIIEVSHQR 366 L+GGNID +++ ++ + L + R Q+ + +VD+PG L ++ L A ANI+++ + R Sbjct: 302 LSGGNIDAQMLNIIIEKGLFKSYRKMQIYVTLVDKPGALLHLTDSLKIANANIVKIDYDR 361 Query: 367 TFSDLPAKATLLELVIETRDRAHLEEVLARLGAEGFAVRET 407 + L ++ + +ET+ + H EE+ L + F E+ Sbjct: 362 FSTKLDYGDAMISITLETKGKEHQEEIRKILTQKAFNFYES 402 >VNG2100G [E] COG1171 Threonine dehydratase Hbs Halobacterium sp. NRC-1 Length = 495 Score = 276 bits (705), Expect = 9e-74, Method: Compositional matrix adjust. Identities = 161/398 (40%), Positives = 240/398 (60%), Gaps = 3/398 (0%) Query: 10 ITLADIRRAADVIRDAVMVTACNESRTLGEICGCRLFLKFENLQFTATFKERGALNRLQA 69 ++L+DIR A + + + T S T ++ G + K E Q T +FK RGA NR++ Sbjct: 87 LSLSDIRDARERVSETARHTPLEYSHTFSDLTGADVRPKLECFQRTGSFKIRGATNRIRT 146 Query: 70 LSPEERKRGVIAMSAGNHAQGVAYHAKRLGIPATIVMPIGTPMVKIENTRRHGAEVIITG 129 LS +++ GV+ SAGNHAQGVA A R G+ + +VMP P+ KI+ T+ +GAEV++ G Sbjct: 147 LSADQQDAGVVTASAGNHAQGVALAASRSGVDSKVVMPESAPISKIKATKSYGAEVVLHG 206 Query: 130 QTLEECFAFVGSHAAQKGLILIHPYDDPLIIAGQGTIGLEMLAAVPELDILVVPIGGGGL 189 ++ A A +G +H +DD I+AGQGT+GLE+ A P +D +VVPIGGGGL Sbjct: 207 ADYDDAQAHAHELEAAEGRTYVHAFDDEYIMAGQGTLGLEIAADCPTVDTVVVPIGGGGL 266 Query: 190 ISGIATAAKALKPSIQVVGVQAQLYPSMYNAV-KGE-QLPMRGDTLAEGIAVKAPGQITT 247 ISG+ATA K ++V+GVQA+ ++ ++ KG+ Q DT+A+GIAV+ G T Sbjct: 267 ISGVATALKGELDDVRVIGVQAEGASTVARSLDKGQPQAVDHVDTIADGIAVRQVGAQTF 326 Query: 248 KIVRQLVDDIILVSEDQIERAVATLISIEKTVVEGAGAAGLAAVLAAPARFA-GHNVGLV 306 ++++ VD+++ VS+D+I A+ L+ KT+VEGAGA LAAVL +A G + Sbjct: 327 PVIQEHVDEVVTVSDDEIATALVLLLERGKTLVEGAGATALAAVLEDKFEYADGETIVPA 386 Query: 307 LTGGNIDTRLIASVLTRELAREGRLTQLALDIVDRPGQLAAVSILLADAGANIIEVSHQR 366 L GGNID L+ +V+ R L +GR ++ + D PG L + A+ ANI + H R Sbjct: 387 LCGGNIDLNLLTTVIVRGLVDQGRYVKIRTVLKDSPGSLNDLLATAAEERANIYAIQHDR 446 Query: 367 TFSDLPAKATLLELVIETRDRAHLEEVLARLGAEGFAV 404 T D+ AT +EL +ETR H++ +L R+ EGF V Sbjct: 447 TNRDIAMNATEVELDLETRGPEHVDRLLTRIQDEGFDV 484 >TVN0190 [E] COG1171 Threonine dehydratase Tvo Thermoplasma volcanium Length = 406 Score = 269 bits (688), Expect = 7e-72, Method: Compositional matrix adjust. Identities = 147/399 (36%), Positives = 229/399 (57%), Gaps = 2/399 (0%) Query: 11 TLADIRRAADVIRDAVMVTACNESRTLGEICGCRLFLKFENLQFTATFKERGALNRLQAL 70 + +I A + V T S T+G+ G ++ K EN Q T +FK RGA+ R L Sbjct: 8 SFDEIIEAQRYLEGKVNRTPLIRSTTIGKEYGADIYFKLENFQKTGSFKSRGAIFRFSKL 67 Query: 71 SPEERKRGVIAMSAGNHAQGVAYHAKRLGIPATIVMPIGTPMVKIENTRRHGAEVIITGQ 130 S +E++ GVI SAGNHAQGVAY A GI A IVMP T K+ +GA VI+ G Sbjct: 68 SEDEKRHGVITASAGNHAQGVAYAAMINGIDAKIVMPEYTIPQKVNAVISYGAHVILKGS 127 Query: 131 TLEECFAFVGSHAAQKGLILIHPYDDPLIIAGQGTIGLEMLAAVPELDILVVPIGGGGLI 190 +E + A Q+G I I ++D +I+GQGTIGLE++ +P++DI++VP+GGGGLI Sbjct: 128 DYDEAHRYADEIAKQEGRIFIEAFNDRWVISGQGTIGLEIMEDLPDVDIILVPVGGGGLI 187 Query: 191 SGIATAAKALKPSIQVVGVQAQLYPSMYNAVKGEQL--PMRGDTLAEGIAVKAPGQITTK 248 SGIA AAK ++V+G++++L SM +++ ++ G ++ +GI+VK PG +T Sbjct: 188 SGIALAAKHASNKVKVIGIESELSDSMKASLREGKIVAHTSGVSICDGISVKYPGVLTFD 247 Query: 249 IVRQLVDDIILVSEDQIERAVATLISIEKTVVEGAGAAGLAAVLAAPARFAGHNVGLVLT 308 I R+ VDDI+ V+E+ + +A+ L K V E +GA GLAA++ G V +V++ Sbjct: 248 IARKYVDDIVTVTEEYVSKAIYKLFERNKIVAEPSGAVGLAAIMEGKVDVKGKKVAIVVS 307 Query: 309 GGNIDTRLIASVLTRELAREGRLTQLALDIVDRPGQLAAVSILLADAGANIIEVSHQRTF 368 GGNI+ L++ ++ +EL G+L ++ I DRPG L +++ +A+ G NI Sbjct: 308 GGNINPLLMSKIIYKELENLGQLVRIECTIPDRPGNLYRIAMAIAENGGNIYHAEVDNLR 367 Query: 369 SDLPAKATLLELVIETRDRAHLEEVLARLGAEGFAVRET 407 + P + + R + HL+ ++ L G+ R T Sbjct: 368 KETPPGFQSVTFTVNVRGQDHLDRIIGSLREMGYLFRIT 406