BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0256.p (1048 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb21498 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizob... 1201 0.0 SMa1662 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobi... 981 0.0 mll6730 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobi... 926 0.0 YPO1001 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 908 0.0 BMEI1629 [V] COG0841 Cation/multidrug efflux pump Bme Brucella m... 871 0.0 >SMb21498 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobium meliloti Length = 1077 Score = 1201 bits (3108), Expect = 0.0, Method: Compositional matrix adjust. Identities = 620/1049 (59%), Positives = 798/1049 (76%), Gaps = 1/1049 (0%) Query: 1 MISAVFVDRPRLAIVIAFVITIAGALALMQIPVAQFPDIVPPQVTVSAVFPGASAEVVES 60 MIS +F+DRPR A VI+ V+T+AG +AL ++P+AQFPDIVPPQV+V+A +PGA A+VVE+ Sbjct: 1 MISEIFIDRPRFAAVISIVLTLAGLIALTRLPIAQFPDIVPPQVSVTASYPGAGADVVEA 60 Query: 61 SVAQPLEAQVVGVDKMLYMKSTSGNDGSYTLTVSFALGTDPDINTVNVNNRVQSALAQLP 120 +VAQPLE++VVGVD MLYMKSTSG DG+Y+LTV+FA+GTDPDI TVNV NRV A LP Sbjct: 61 TVAQPLESKVVGVDNMLYMKSTSGADGTYSLTVTFAVGTDPDIATVNVQNRVALAEPVLP 120 Query: 121 TEVQAQGLTVQKKSSAVLQFIVLYSKSGEQDPLFITNYAIINVLDAISRTPGVGQASLFA 180 EV+ G++VQK+SS+++Q I ++ ++ E D LF++NYA INVLD I R PGVG A+LF Sbjct: 121 AEVKQSGVSVQKRSSSLMQVIAIHGENDEFDNLFLSNYATINVLDTIKRVPGVGDATLFG 180 Query: 181 KLNYSMRIWFDTQRLTSLNLAPSDVIAAIRAQSVQAPVGRIGARPISNDQQFQFNVQTQG 240 +YSMR+ D RLT+L L P+DVI A++ Q+VQA +GRIGA+P+++D FQ N+QTQG Sbjct: 181 AQDYSMRVVLDIDRLTNLGLTPTDVINALKTQNVQAAIGRIGAQPMTDDPLFQLNIQTQG 240 Query: 241 RLTTSKQFGDIVLRANPDGSVLRIRDVARVEIGAQNMDSESRIDGNPGVPMGIYLAPGAN 300 RLT QF D+VLRA PDGS +RIRDVARVE+G+ + DS +RI+G P +G Y APGAN Sbjct: 241 RLTDPAQFEDVVLRAEPDGSFVRIRDVARVELGSVSADSTARINGKPVAMIGTYQAPGAN 300 Query: 301 AVTTAKAVQATLARLSERFPPGLTYLVQYDSTTFVSDTIKEVMKTLGEAFVLVVIVVFLF 360 A+ + VQ + RL+ FP GLTY V YD++ FV +++ V TL EAF LV+IVVFLF Sbjct: 301 ALAATEGVQQAMNRLAAAFPEGLTYTVSYDTSDFVQASVENVEHTLLEAFALVIIVVFLF 360 Query: 361 LGNLRATVIPAVAVPVSLIGAFAVLLALGYSANTVSLLAMVLAIGIVVDDAIVVVENVER 420 LGN RA +IP +AVPV+L+G FAV+LA+G+S NTVSLLA+VLAIGIVVDDAIVVVENVER Sbjct: 361 LGNWRAALIPLIAVPVALVGTFAVILAMGFSLNTVSLLALVLAIGIVVDDAIVVVENVER 420 Query: 421 VMEEEPELSPADATKKAMAQITAPIIAISLVLLSVFVPIAFIPGISGTLFRQFAVTISAA 480 VMEE P +S A A + AM +IT I+AI+LVLLSVFVP+AFIPG+SG LF+QFAV +S + Sbjct: 421 VMEENPGMSAAQAARLAMGEITGAIVAITLVLLSVFVPVAFIPGLSGQLFQQFAVAVSVS 480 Query: 481 MVISALNALTLSPALCAVFLR-HGGPRRGIMGRVLGSIDWVRDRYAGVVQRLVRVAVLSL 539 MVISA+NALTLSPALCA+ L+ H GP+RGI+G + ID R+ YA V + R A++ + Sbjct: 481 MVISAINALTLSPALCAILLKPHHGPKRGILGWISRGIDRTRNGYAHVAGSIARRAIIGV 540 Query: 540 VAVLVFAGAVFGVSKITPTGFLPEEDQGAFFIAVQLPDGASVARTSEVTKQVETLLKKNP 599 + + V GA + +I PTGFLP EDQGAFF ++LP+GAS RT V ++VET+L Sbjct: 541 ILLAVAIGASGWLFRIVPTGFLPSEDQGAFFAEIRLPEGASFNRTDAVVREVETMLGGIE 600 Query: 600 AIDHVLSIIGFSLLDGASEPNSAFMVARMKAFADRKAVTDSVQAAIGQTFVGGSQIRQAS 659 + +V ++ G+S LDG ++ +SAF + MK FA+R+ + SV AAIG G+ IR A Sbjct: 601 GVANVTTVTGYSFLDGIAKSSSAFAIVTMKPFAERQDESASVNAAIGTVMAKGAAIRNAQ 660 Query: 660 VLPFNLPPIIGLSTSGGFEYQLEALEGQDPASLSSVMGGLIGAANRNPNLARVFSTFTAT 719 V FNLPPIIGL T GFEYQL L+G+ PA L++ GGL+ AAN+NP L FST++A+ Sbjct: 661 VFAFNLPPIIGLGTGSGFEYQLLDLQGRSPAELAATAGGLMVAANQNPQLGPTFSTYSAS 720 Query: 720 NPSVYLDIDRAKAQALGLNMADVFTALQATLGGIYVNNFNLFGRTWQVNVQGDAADRRDI 779 +P +YL++DR + QALG++++D+F LQ TLG YVN+FNLFGR+W+V +Q ADR + Sbjct: 721 SPQLYLNLDRDRLQALGVSVSDLFATLQGTLGSYYVNDFNLFGRSWKVTMQAAEADRDAV 780 Query: 780 PDIWQIYVRNSGGEMVPIRSIASLRIVTGPQVITRYNNYRSVTVNGSPAPGVSSGTAIAT 839 DI +++VRN+ G+MVP+ S+A + + GPQ I RYNNYRS+T+NG PAPG+SSG A+A Sbjct: 781 DDISRLHVRNAAGDMVPVASVARVDYIVGPQSIVRYNNYRSITLNGQPAPGISSGQALAA 840 Query: 840 MADLSKSTLPSGYSYEWTGTAYQEQAASGQTGIILGLAVLFAYLFLVALYESWTIPIPVL 899 M +S +TLP GYS+EWTGTA QE A+GQT +IL LA+LFAYLFLVALYESWTIPIPVL Sbjct: 841 MEQVSAATLPPGYSFEWTGTALQELEAAGQTTVILALALLFAYLFLVALYESWTIPIPVL 900 Query: 900 LSVTVGVFGSYLAIKLAGLNLDLYGQIGLVVLIALAAKNGILIVEFAKEQREAGRPIAEA 959 LSV+VGV G+ +A+ +AGL+ D+Y QIGLVVLIALA+KN ILIVEFAK QRE G I +A Sbjct: 901 LSVSVGVAGALVAVLVAGLSFDIYAQIGLVVLIALASKNAILIVEFAKFQREKGATIVDA 960 Query: 960 ATMGAQMRFRAVMMTSIAFILGLVPLVVATGAAEISRRAVGTAVFGGMLAASSVGIFLVP 1019 A GA+ RFRAVMMTS AFI+GL+PLV A GA +SRRAVGT V GGMLAAS +GIF++P Sbjct: 961 AVEGARTRFRAVMMTSFAFIVGLIPLVTADGAGMLSRRAVGTGVAGGMLAASLLGIFIIP 1020 Query: 1020 MLFVTFQGWREAAKNRFGRRGKAEQPASH 1048 L+V FQ RE G A A H Sbjct: 1021 ALYVVFQWLRERGHKLAGLSSHAAGEAPH 1049 >SMa1662 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobium meliloti Length = 1044 Score = 981 bits (2536), Expect = 0.0, Method: Compositional matrix adjust. Identities = 495/1038 (47%), Positives = 714/1038 (68%), Gaps = 4/1038 (0%) Query: 2 ISAVFVDRPRLAIVIAFVITIAGALALMQIPVAQFPDIVPPQVTVSAVFPGASAEVVESS 61 +SA F+DRPRLA VIA V+ IAGALAL QIP+AQFP I PP+V V+A +PGA+A V+E S Sbjct: 3 LSAHFIDRPRLATVIAVVMAIAGALALFQIPIAQFPQITPPEVQVTASYPGANASVLEES 62 Query: 62 VAQPLEAQVVGVDKMLYMKSTSGNDGSYTLTVSFALGTDPDINTVNVNNRVQSALAQLPT 121 V P+E QV GV+ MLYM S+S N+G+Y+LTV+FA+GTDP + VNV NRV A +LP Sbjct: 63 VGAPIEDQVNGVEDMLYMSSSSTNNGTYSLTVTFAVGTDPALAQVNVQNRVALATPRLPA 122 Query: 122 EVQAQGLTVQKKSSAVLQFIVLYSKSGEQDPLFITNYAIINVLDAISRTPGVGQASLFAK 181 V G++V+ +SS++L + +YS G +D +FI+NYA N+ DAI+R GVG+A +F Sbjct: 123 SVTQTGVSVRARSSSMLMGVAIYSPEGTRDEIFISNYAANNIRDAIARVAGVGEAGIFGP 182 Query: 182 LNYSMRIWFDTQRLTSLNLAPSDVIAAIRAQSVQAPVGRIGARPISNDQQFQFNVQTQGR 241 +YSMRIW + R+ +L L +D+ +AI+AQ+ QA G++G+ P ++ QQ Q + QGR Sbjct: 183 -SYSMRIWMNPDRMQALGLTATDLTSAIQAQNAQASAGQLGSPPATSGQQLQLTIMAQGR 241 Query: 242 LTTSKQFGDIVLRANPDGSVLRIRDVARVEIGAQNMDSESRIDGNPGVPMGIYLAPGANA 301 L T + F +I++R N +G+++R+RDVARVE+GAQ+ D+ S +G P + +Y + ANA Sbjct: 242 LATEEDFSNIIVRTNTEGALVRLRDVARVELGAQSYDTASTFNGQPSATVVVYQSAEANA 301 Query: 302 VTTAKAVQATLARLSERFPPGLTYLVQYDSTTFVSDTIKEVMKTLGEAFVLVVIVVFLFL 361 + ++AV + L RLS +FP + Y + +D+T F+++TIKE+ TL F LVV V + FL Sbjct: 302 LAVSRAVLSELDRLSRQFPEDVAYAIVFDTTAFITETIKEIAITLAITFALVVAVTYFFL 361 Query: 362 GNLRATVIPAVAVPVSLIGAFAVLLALGYSANTVSLLAMVLAIGIVVDDAIVVVENVERV 421 + RATVIP + +PVSLIG FAVL L YSANT++L A++LAI +VVDDAI+VVENV+R+ Sbjct: 362 QDWRATVIPTLTIPVSLIGGFAVLYLLDYSANTITLFAVILAISLVVDDAIIVVENVKRL 421 Query: 422 MEEEPELSPADATKKAMAQITAPIIAISLVLLSVFVPIAFIPGISGTLFRQFAVTISAAM 481 M EE L+ DAT++ M+Q+T PI+A +LVL ++FVPIAF+ GI+G L+RQF+VTI + Sbjct: 422 MAEE-RLNVHDATRRTMSQVTGPIVATTLVLAALFVPIAFVAGITGQLYRQFSVTILITI 480 Query: 482 VISALNALTLSPALCAVFLRHGGPRR-GIMGRVLGSIDWVRDRYAGVVQRLVRVAVLSLV 540 S +NALTLSPALC + LR +R GI G +D+ R+ Y ++ R+ R ++ V Sbjct: 481 TFSTINALTLSPALCVLMLRSPREQRSGIFGTFNRGLDFSRNWYVAMLDRMSRRLWIASV 540 Query: 541 AVLVFAGAVFGVSKITPTGFLPEEDQGAFFIAVQLPDGASVARTSEVTKQVETLLKKNPA 600 +L G V+G+ + PTGF+P EDQG FI VQLP+ AS+ RT + V +L++ P Sbjct: 541 ILLAILGGVYGLFRALPTGFVPSEDQGYLFINVQLPNAASLERTQQALDTVSRILQRTPG 600 Query: 601 IDHVLSIIGFSLLDGASEPNSAFMVARMKAFADRKAVTDSVQAAIGQTFVGGSQIRQASV 660 + + + I G S++ G N+ ++ +K + +R++ +S+ A + + +I ASV Sbjct: 601 VANSVGIAGNSMVGGGGS-NAGMVITALKPWGERRSAEESIDAIMNRLRADFGRIPTASV 659 Query: 661 LPFNLPPIIGLSTSGGFEYQLEALEGQDPASLSSVMGGLIGAANRNPNLARVFSTFTATN 720 +PFN P I GL T+GGF+ +L+A GQ ++ VM GLI AN+ P LA VFSTF+A Sbjct: 660 VPFNPPAIPGLGTTGGFDLRLQARSGQSQQEIAEVMRGLIVKANQTPGLASVFSTFSADV 719 Query: 721 PSVYLDIDRAKAQALGLNMADVFTALQATLGGIYVNNFNLFGRTWQVNVQGDAADRRDIP 780 P V+L++DR +A+ G++ A +F A+Q+ LG YV++FN+F R +QV +Q + R I Sbjct: 720 PQVFLNVDRRRAELFGVSTATIFNAMQSHLGSSYVDDFNIFSRVYQVRIQDEPQFRSRIE 779 Query: 781 DIWQIYVRNSGGEMVPIRSIASLRIVTGPQVITRYNNYRSVTVNGSPAPGVSSGTAIATM 840 DI ++ VR+ GE+VP++S+ S+ GP I RYN + S ++NG A G S+G A+ATM Sbjct: 780 DIQRLRVRSRNGELVPLQSLLSISTSYGPTAINRYNLFPSASINGQAATGTSTGQALATM 839 Query: 841 ADLSKSTLPSGYSYEWTGTAYQEQAASGQTGIILGLAVLFAYLFLVALYESWTIPIPVLL 900 A L++ LP G+ +EWTG A QE+ A QT +IL + ++F YLFLV YESW++P+ V+L Sbjct: 840 ASLAEQNLPEGFGFEWTGLALQEEQAGNQTALILLMGLIFTYLFLVGQYESWSVPLAVML 899 Query: 901 SVTVGVFGSYLAIKLAGLNLDLYGQIGLVVLIALAAKNGILIVEFAKEQREAGRPIAEAA 960 SV V V G+ + + LA +++++Y QIGLV+LI LAAKN ILIVEFAKE+R+ G EAA Sbjct: 900 SVAVAVLGALVGLMLASIDINIYAQIGLVLLIGLAAKNAILIVEFAKERRDKGMATPEAA 959 Query: 961 TMGAQMRFRAVMMTSIAFILGLVPLVVATGAAEISRRAVGTAVFGGMLAASSVGIFLVPM 1020 G RFR V+MT++A ILG++PLV+ATGA SRRA+G VFGG+L + VG+ L+P+ Sbjct: 960 AAGTAQRFRPVLMTAMASILGVIPLVIATGAGAGSRRAIGMTVFGGLLVGTVVGLLLIPV 1019 Query: 1021 LFVTFQGWREAAKNRFGR 1038 +V Q RE AK RF R Sbjct: 1020 FYVLVQTVREQAKERFFR 1037 >mll6730 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobium loti Length = 1055 Score = 926 bits (2392), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/1038 (46%), Positives = 702/1038 (67%), Gaps = 4/1038 (0%) Query: 1 MISAVFVDRPRLAIVIAFVITIAGALALMQIPVAQFPDIVPPQVTVSAVFPGASAEVVES 60 MIS +F+ R RLAIV++ VI+IAGA+A+ +PV Q+P+I PP V+V+A +PGASAEV+ Sbjct: 1 MISDLFITRTRLAIVLSIVISIAGAIAIFSLPVQQYPEITPPTVSVTAFYPGASAEVIAD 60 Query: 61 SVAQPLEAQVVGVDKMLYMKSTSGNDGSYTLTVSFALGTDPDINTVNVNNRVQSALAQLP 120 V PLE + GV M+YM STS N G Y+L+V+F +GT+PDI VNV NR Q A++QLP Sbjct: 61 VVGGPLETAINGVPNMMYMSSTSSNAGQYSLSVTFEVGTNPDIAQVNVQNRAQLAISQLP 120 Query: 121 TEVQAQGLTVQKKSSAVLQFIVLYSKSGEQDPLFITNYAIINVLDAISRTPGVGQASLFA 180 V QG++V+ +S + I YS + D L ITN+ + DA+SR GVG+AS+ Sbjct: 121 AAVTQQGVSVRSRSPDFVLGIAFYSPDSKLDVLQITNFTSTTIADALSRVSGVGEASVVG 180 Query: 181 KLNYSMRIWFDTQRLTSLNLAPSDVIAAIRAQSVQAPVGRIGARPISNDQQFQFNVQTQG 240 YSMRIW + R+ +L + DV AAI+ Q++QA +G+ GA P + Q+ + +G Sbjct: 181 ASEYSMRIWLNPARMDALGITADDVAAAIQRQNIQASLGQAGAPPAREGTELQYTLVARG 240 Query: 241 RLTTSKQFGDIVLRANPDGSVLRIRDVARVEIGAQNMDSESRIDGNPGVPMGIYLAPGAN 300 RL ++ +FGDIV+R G+++R+ D+AR+E+GA++ S + G+ + I APGAN Sbjct: 241 RLLSTDEFGDIVIRTGEAGAIVRLHDIARIELGARSYSSSASFAGHDTAMLQINQAPGAN 300 Query: 301 AVTTAKAVQATLARLSERFPPGLTYLVQYDSTTFVSDTIKEVMKTLGEAFVLVVIVVFLF 360 A+ TA AV+A L RLS FPPGL Y V YD+T FV ++ +++ LGEAF++V++V +LF Sbjct: 301 AIQTANAVRAELQRLSPTFPPGLQYQVVYDATRFVRTSLSLIVRILGEAFLIVLVVTYLF 360 Query: 361 LGNLRATVIPAVAVPVSLIGAFAVLLALGYSANTVSLLAMVLAIGIVVDDAIVVVENVER 420 L + RAT++ A+A+PV+++GA AVLLA GYS N++SLLA+VLAIG+V DDAI+VVENV+ Sbjct: 361 LQDWRATLVSALAMPVAMLGAIAVLLAFGYSINSISLLALVLAIGLVADDAILVVENVKH 420 Query: 421 VMEEEPELSPADATKKAMAQITAPIIAISLVLLSVFVPIAFIPGISGTLFRQFAVTISAA 480 VME++P + A +KAM QIT PII+ +LVLL+V +P AF+ GISG L+RQFAVT+SAA Sbjct: 421 VMEDDPTVETVAAARKAMGQITGPIISTTLVLLAVVIPTAFLSGISGQLYRQFAVTLSAA 480 Query: 481 MVISALNALTLSPALCAVFLRHGGPRRGI--MGRVLGSIDWVRDRYAGVVQRLVRVAVLS 538 +VIS++ LTLSPAL A+ LR G +G ++ R Y +V LVR+ ++ Sbjct: 481 LVISSVVGLTLSPALAAILLRRGQRGYRRGPLGWFARFMNATRVGYGRLVGFLVRLWIIP 540 Query: 539 LVAV-LVFAGAVFGVSKITPTGFLPEEDQGAFFIAVQLPDGASVARTSEVTKQVETLLKK 597 L A+ F GA S + P+ FLP+EDQGA F+ +QLP+ AS+ RT + +V+ L Sbjct: 541 LAALAACFLGAYLLFSGL-PSTFLPDEDQGALFVDIQLPNAASLDRTRAIVGEVQKTLSA 599 Query: 598 NPAIDHVLSIIGFSLLDGASEPNSAFMVARMKAFADRKAVTDSVQAAIGQTFVGGSQIRQ 657 +++V+S+ GFS++ G PN A +VA + + R + A + + S I Sbjct: 600 TKGVENVISVAGFSIVQGTQSPNGAMVVAALDPWDQRNTPDLRLDAILARLRAQFSTIPG 659 Query: 658 ASVLPFNLPPIIGLSTSGGFEYQLEALEGQDPASLSSVMGGLIGAANRNPNLARVFSTFT 717 A+V F+ P I G+ GG + +L+AL+GQ P +++V+ + A N+ P + V +TF+ Sbjct: 660 ANVAVFSPPAISGIGAVGGLDLRLQALQGQPPEEIAAVVRAFVTAINQAPEIGGVATTFS 719 Query: 718 ATNPSVYLDIDRAKAQALGLNMADVFTALQATLGGIYVNNFNLFGRTWQVNVQGDAADRR 777 A P +Y+D+DR +A+ALG++++D+++ + A+ G YVN+F L GR +QVN+Q DA R Sbjct: 720 ADVPQIYVDVDRTRAEALGVSVSDIYSTIGASFGSRYVNDFTLHGRVFQVNLQADAEHRG 779 Query: 778 DIPDIWQIYVRNSGGEMVPIRSIASLRIVTGPQVITRYNNYRSVTVNGSPAPGVSSGTAI 837 D DI ++VR+ G MVP+R++ S V P VI+RYN + +NG APG SSG A+ Sbjct: 780 DAEDILNLHVRSRTGAMVPLRAVVSTSTVLAPFVISRYNLSVAAQINGQVAPGGSSGAAM 839 Query: 838 ATMADLSKSTLPSGYSYEWTGTAYQEQAASGQTGIILGLAVLFAYLFLVALYESWTIPIP 897 + ++ LP+GY YEW+G ++QE+ ++GQ +I GLA LFAYLFLVA YESW +PI Sbjct: 840 DAIERVAAEALPAGYGYEWSGLSFQERRSAGQESVIFGLAFLFAYLFLVAQYESWMLPIA 899 Query: 898 VLLSVTVGVFGSYLAIKLAGLNLDLYGQIGLVVLIALAAKNGILIVEFAKEQREAGRPIA 957 V+LS+ +FG+ A+ L GL LY QI +V+LI LA+KN ILIVEFAKE+RE G+ IA Sbjct: 900 VILSLGAALFGATGALVLFGLQNSLYVQIAIVLLIGLASKNAILIVEFAKERREEGQSIA 959 Query: 958 EAATMGAQMRFRAVMMTSIAFILGLVPLVVATGAAEISRRAVGTAVFGGMLAASSVGIFL 1017 EAA +GA+ RFRAVMMT+++FILG++PL V+TGA +R+AVG +FGGMLAA+++G+F+ Sbjct: 960 EAARLGAEQRFRAVMMTALSFILGIIPLAVSTGAGAGARQAVGVTIFGGMLAATTIGLFI 1019 Query: 1018 VPMLFVTFQGWREAAKNR 1035 +P LF Q E A R Sbjct: 1020 IPALFAAIQHIAEWATVR 1037 >YPO1001 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1039 Score = 908 bits (2347), Expect = 0.0, Method: Compositional matrix adjust. Identities = 501/1032 (48%), Positives = 692/1032 (67%), Gaps = 7/1032 (0%) Query: 6 FVDRPRLAIVIAFVITIAGALALMQIPVAQFPDIVPPQVTVSAVFPGASAEVVESSVAQP 65 F+ RP+ AIVIA VIT+ G ++L IPV Q+PDI PP V+VSAV+PGASA V +VA P Sbjct: 5 FIRRPKFAIVIALVITLVGWVSLYVIPVEQYPDITPPVVSVSAVYPGASARDVAQAVASP 64 Query: 66 LEAQVVGVDKMLYMKSTSGNDGSYTLTVSFALGTDPDINTVNVNNRVQSALAQLPTEVQA 125 LEAQV GV MLYM+STS N+GSY L+++FA GTDPD+ V V NR+ AQLP EV Sbjct: 65 LEAQVNGVSHMLYMESTSANNGSYQLSITFASGTDPDMAAVEVQNRISQVSAQLPAEVNE 124 Query: 126 QGLTVQKKSSAVLQFIVLYSKSGEQDPLFITNYAIINVLDAISRTPGVGQASLFAKLNYS 185 G++V+K++S +L + ++S D LF++NY I + DAI+R GVG +F +YS Sbjct: 125 NGISVRKRASNLLLGVSVFSPQQTHDALFVSNYTSIQLRDAIARISGVGDVQVFGARDYS 184 Query: 186 MRIWFDTQRLTSLNLAPSDVIAAIRAQSVQAPVGRIGARPISNDQQFQFNVQTQGRLTTS 245 MR+W D QR+ SLN++ D++AA++ Q+VQA G+IG+ P +QQ + QGRLT + Sbjct: 185 MRVWLDPQRMESLNVSVQDIVAALQQQNVQAAAGQIGSSPSMPNQQQTLTISGQGRLTDA 244 Query: 246 KQFGDIVLRANPDGSVLRIRDVARVEIGAQNMDSESRIDGNPGVPMGIYLAPGANAVTTA 305 +QF D+++R+NP G ++R+ DVARV +GAQN + + + +Y PGANA+ A Sbjct: 245 RQFADVIIRSNPQGGMIRLGDVARVALGAQNYQVSAAQNQTESAFLVVYPVPGANALNVA 304 Query: 306 KAVQATLARLSERFPPGLTYLVQYDSTTFVSDTIKEVMKTLGEAFVLVVIVVFLFLGNLR 365 V+ +ARLS FP LTY + YDST V+ T+ E+ +L ++V+ VV+LFL +LR Sbjct: 305 NGVRDEMARLSAAFPADLTYEINYDSTLPVTATLHEIAVSLTLTLIVVLAVVYLFLQSLR 364 Query: 366 ATVIPAVAVPVSLIGAFAVLLALGYSANTVSLLAMVLAIGIVVDDAIVVVENVERVMEEE 425 AT I A+ VPVSL+G FAVL GYSANT+SL A++LA+ IVVDDAIVVVENVER++ + Sbjct: 365 ATFIVALTVPVSLLGTFAVLYVFGYSANTLSLFAIILALTIVVDDAIVVVENVERLLSND 424 Query: 426 PELSPADATKKAMAQITAPIIAISLVLLSVFVPIAFIPGISGTLFRQFAVTISAAMVISA 485 P LSPA+AT++AM+QI PIIA +LVL++VFVPIA +PGI G L+RQFAVT+SAA+++S+ Sbjct: 425 PHLSPAEATRQAMSQIAGPIIATTLVLMAVFVPIAILPGIIGELYRQFAVTLSAAVILSS 484 Query: 486 LNALTLSPALCAVFL-RHGGPRRGIMGRVLGSIDWVRDRYAGVVQRLVRVAVLSLVAVLV 544 +NALTLSPALCAV L R G+ G + +D RD Y G+ R+ R AV S+ A+L+ Sbjct: 485 INALTLSPALCAVLLKRRTLATTGMFGTINKGLDRARDGYVGLTGRINRRAVFSIAALLL 544 Query: 545 FAGAV-FGVSKITPTGFLPEEDQGAFFIAVQLPDGASVARTSEVTKQVETLLKKNPAIDH 603 A +G S++ PT FLPEEDQG FF+++QLPDGAS+ RT V Q+ + N A++ Sbjct: 545 VGLATWWGYSRL-PTSFLPEEDQGYFFVSLQLPDGASLNRTQTVMDQMYQQVSTNEAVED 603 Query: 604 VLSIIGFSLLDGASEPNSAFMVARMKAFADRKAVTDSVQAAIGQTFVGGSQIRQASVLPF 663 V+ I GFSLL G + PN+ F + +K + R + D V A+I I A ++ Sbjct: 604 VIKITGFSLLSGNNAPNAGFAIVMLKPWGQRPHI-DRVLASIQANLAA---IPSAMIMAV 659 Query: 664 NLPPIIGLSTSGGFEYQLEALEGQDPASLSSVMGGLIGAANRNPNLARVFSTFTATNPSV 723 N P I GL ++ GF+ +++AL GQ P L+ V G+I AAN++P L+RVF+TF+A+ P Sbjct: 660 NPPAIAGLGSASGFDLRIQALLGQSPQELAQVSQGIIFAANQDPTLSRVFTTFSASVPET 719 Query: 724 YLDIDRAKAQALGLNMADVFTALQATLGGIYVNNFNLFGRTWQVNVQGDAADRRDIPDIW 783 L IDR +A L + ++ +F LQ +LGG+ +F L R ++V +Q D R+ I Sbjct: 720 NLSIDRDRAALLQVPVSRIFQTLQTSLGGMNAGDFTLNNRMFRVQLQNDMNFRQRTAQIN 779 Query: 784 QIYVRNSGGEMVPIRSIASLRIVTGPQVITRYNNYRSVTVNGSPAPGVSSGTAIATMADL 843 + VR+ G +V + ++ +L G I+ +N + SV ++GS A G SSG A+A M L Sbjct: 780 NLNVRSDNGALVSLANLVTLTPSVGAPFISNFNQFPSVAISGSAADGASSGQAMAAMEAL 839 Query: 844 SKSTLPSGYSYEWTGTAYQEQAASGQTGIILGLAVLFAYLFLVALYESWTIPIPVLLSVT 903 LP GYSY W+G ++QEQ GQ I A++FAYLFLVA YESW+IP+ V+LSV Sbjct: 840 LAQNLPQGYSYSWSGMSWQEQQTGGQVVFIYLAALVFAYLFLVAQYESWSIPLVVVLSVV 899 Query: 904 VGVFGSYLAIKLAGLNLDLYGQIGLVVLIALAAKNGILIVEFAKEQREAGRPIAEAATMG 963 V G+ + G D+Y QIGLV+LI LAAKN ILIVEF+K +RE G IAEAA G Sbjct: 900 FAVGGAVAGLSAMGFANDVYAQIGLVLLIGLAAKNAILIVEFSKARREEGASIAEAAQDG 959 Query: 964 AQMRFRAVMMTSIAFILGLVPLVVATGAAEISRRAVGTAVFGGMLAASSVGIFLVPMLFV 1023 A+ RFRAVMMT+I+FILG++PLV A+GA +SR+ +G VFGGML A++VGI +P L++ Sbjct: 960 AKQRFRAVMMTAISFILGVMPLVFASGAGAMSRQIIGITVFGGMLMATAVGILFIPALYL 1019 Query: 1024 TFQGWREAAKNR 1035 Q RE KNR Sbjct: 1020 HIQRLREWTKNR 1031 >BMEI1629 [V] COG0841 Cation/multidrug efflux pump Bme Brucella melitensis Length = 1051 Score = 871 bits (2250), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/1020 (44%), Positives = 660/1020 (64%), Gaps = 5/1020 (0%) Query: 6 FVDRPRLAIVIAFVITIAGALALMQIPVAQFPDIVPPQVTVSAVFPGASAEVVESSVAQP 65 FVDRP A VI+ V+ +AG + + +PVAQ+P++ PPQV VSA +PGASAE V +VA P Sbjct: 5 FVDRPVFAAVISIVLVLAGLICIRILPVAQYPELTPPQVVVSATYPGASAETVAQTVAAP 64 Query: 66 LEAQVVGVDKMLYMKSTSGNDGSYTLTVSFALGTDPDINTVNVNNRVQSALAQLPTEVQA 125 LE Q+ GV+ MLYM+S+S G+ LTV+FALGTDPD T+NVNNRVQ A + LP EVQ Sbjct: 65 LEQQINGVENMLYMQSSSLGSGTMQLTVTFALGTDPDQATINVNNRVQRATSSLPQEVQR 124 Query: 126 QGLTVQKKSSAVLQFIVLYSKSGEQDPLFITNYAIINVLDAISRTPGVGQASLFAKLNYS 185 G+TV K+S+ +L + +++ + D ++ NYA++NV+D + R PGVG L ++YS Sbjct: 125 LGVTVDKRSTTILGMVAMFATTDRYDRTYVGNYALLNVVDDLKRLPGVGDVQLLGNIDYS 184 Query: 186 MRIWFDTQRLTSLNLAPSDVIAAIRAQSVQAPVGRIGARPISNDQQFQFNVQTQGRLTTS 245 MR+W RL NL PSDV AAI+ Q+ Q GR G +P + F + TQGRL + Sbjct: 185 MRVWLRPDRLAQYNLTPSDVSAAIQEQNAQFAAGRFGDQPDPHAGPFTYTATTQGRLPDA 244 Query: 246 KQFGDIVLRANP-DGSVLRIRDVARVEIGAQNMDSESRIDGNPGVPMGIYLAPGANAVTT 304 F +I+LR++ + + LR++DVARVE+G ++ S ++G P VP+ IYL PGANA+ T Sbjct: 245 AAFENIILRSSSQNAATLRLKDVARVELGTESYLVNSNLNGTPAVPIAIYLQPGANALNT 304 Query: 305 AKAVQATLARLSERFPPGLTYLVQYDSTTFVSDTIKEVMKTLGEAFVLVVIVVFLFLGNL 364 + +Q + L FP G+ Y + +D+T F+ +I+EV+ T EA +LVV+VVF+FL N Sbjct: 305 MELIQNRMNELKASFPAGIDYAIPFDTTKFIKVSIEEVVHTFIEAIILVVLVVFIFLQNW 364 Query: 365 RATVIPAVAVPVSLIGAFAVLLALGYSANTVSLLAMVLAIGIVVDDAIVVVENVERVMEE 424 RAT+IP +AVP+S+IG FA + LG+S N ++L +VLAIGIVVDDAIVV+ENVER+M Sbjct: 365 RATLIPVIAVPISIIGTFAGMYVLGFSINLLTLFGLVLAIGIVVDDAIVVLENVERIMTT 424 Query: 425 EPELSPADATKKAMAQITAPIIAISLVLLSVFVPIAFIPGISGTLFRQFAVTISAAMVIS 484 E +LSP A KAM ++T P+IAI LVL +VF+P+AF+ G+ G +++QFAVTI+ ++ +S Sbjct: 425 E-KLSPRKAAIKAMGEVTGPVIAIVLVLCAVFIPVAFMGGLVGEMYKQFAVTIAISVTLS 483 Query: 485 ALNALTLSPALCAVFLRHGGPRRGIMGRVLG-SIDWVRDRYAGVVQRLVRVAVLSLVAVL 543 L ALTL+PALCA+ L+ G + R+ + + V Y V+ ++ A + L+ Sbjct: 484 GLVALTLTPALCALILKPGHHEPILPFRIFNRAFERVTSGYTRGVRFFLKRATIGLIIFA 543 Query: 544 VFAGAVFGVSKITPTGFLPEEDQGAFFIAVQLPDGASVARTSEVTKQVETLLKKNPAIDH 603 G+ + + + P LP+EDQG F LP AS+ RT+ V QV ++KNPA+D+ Sbjct: 544 GLLGSTYYLFERVPGSLLPDEDQGFLFGVAVLPPAASLERTTVVLDQVSENIRKNPAVDN 603 Query: 604 VLSIIGFSLLDGASEPNSAFMVARMKAFADRKAVTDSVQAAIGQTFVG-GSQIRQASVLP 662 V ++ GF LL G + ++ M +K + +R D+ + +T +G + I+ VL Sbjct: 604 VFAVSGFDLLSGGLKTSAGTMFIMLKDWKER-TTPDADARNLPRTIMGMNAGIKDGMVLA 662 Query: 663 FNLPPIIGLSTSGGFEYQLEALEGQDPASLSSVMGGLIGAANRNPNLARVFSTFTATNPS 722 FN PPI+GLST+GGFE ++ G SL+ + AA + P L V +TF P Sbjct: 663 FNPPPIMGLSTTGGFELYVQDRTGGGVESLTQATKLITEAAAKRPELQGVRTTFDPYVPQ 722 Query: 723 VYLDIDRAKAQALGLNMADVFTALQATLGGIYVNNFNLFGRTWQVNVQGDAADRRDIPDI 782 + +DR KA+A+G+ + VFTA+QAT G +YVN+F L+GR +QVN+Q +A RRD D+ Sbjct: 723 YDIQLDREKAKAMGVPINSVFTAMQATFGSLYVNDFTLYGRNYQVNLQSEAEFRRDPGDL 782 Query: 783 WQIYVRNSGGEMVPIRSIASLRIVTGPQVITRYNNYRSVTVNGSPAPGVSSGTAIATMAD 842 ++VR G M+P+ ++ +++ + GP + R+N + + V G+PAPG +SG AI M + Sbjct: 783 KHVFVRADSGSMIPLDALVTVKRIVGPDQLERFNAFNAAKVTGNPAPGYTSGDAIKAMQE 842 Query: 843 LSKSTLPSGYSYEWTGTAYQEQAASGQTGIILGLAVLFAYLFLVALYESWTIPIPVLLSV 902 ++ LP GY WTG+AYQE + SG + ++ +L L A YE W++P+ V+ +V Sbjct: 843 VAAQVLPQGYQIAWTGSAYQEVSTSGTGSQAMIFGLIMVFLILAAQYERWSLPLAVITAV 902 Query: 903 TVGVFGSYLAIKLAGLNLDLYGQIGLVVLIALAAKNGILIVEFAKEQREAGRPIAEAATM 962 +FG+ LA L GL D+Y QIGLV LI LA KN ILIVEFA +RE+G+ EAA Sbjct: 903 PFAIFGALLATDLRGLTNDVYFQIGLVTLIGLAVKNAILIVEFAVLERESGKSAIEAAAS 962 Query: 963 GAQMRFRAVMMTSIAFILGLVPLVVATGAAEISRRAVGTAVFGGMLAASSVGIFLVPMLF 1022 A++RFR ++MTS+ FILG+VPL V+TGA SR ++GT V GGMLAA+ + F +PM + Sbjct: 963 AARLRFRPIVMTSLTFILGVVPLAVSTGAGSASRHSIGTGVIGGMLAATFIATFFIPMFY 1022