BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0236.p (1603 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll4104 [E] COG2902 NAD-specific glutamate dehydrogenase Mlo Mes... 1415 0.0 SMc04085 [E] COG2902 NAD-specific glutamate dehydrogenase Sme Si... 1404 0.0 AGc5015 [E] COG2902 NAD-specific glutamate dehydrogenase Atu Agr... 1396 0.0 BMEI0231 [E] COG2902 NAD-specific glutamate dehydrogenase Bme Br... 1348 0.0 CC0088 [E] COG2902 NAD-specific glutamate dehydrogenase Ccr Caul... 1244 0.0 >mll4104 [E] COG2902 NAD-specific glutamate dehydrogenase Mlo Mesorhizobium loti Length = 1612 Score = 1415 bits (3663), Expect = 0.0, Method: Compositional matrix adjust. Identities = 779/1588 (49%), Positives = 1012/1588 (63%), Gaps = 23/1588 (1%) Query: 26 PRAFAEPLFGYTNIEDLANYDAASLALLAEQAWEHVQRRTAGSADIRVVNPT--LPNGRE 83 P A+ L ED+A Y+AA LA AE A + V G + V + + GR Sbjct: 32 PARLADYLLARAPAEDIAAYEAADLARAAELAGQAVAGHKKGGCVVAVDTDSGVVREGRP 91 Query: 84 ISVLEILNDNMPFLFDSTMAELAEQGLEVTLVAHPIIAVERDDGG-KLLRFYGEALPEGA 142 ++V+ ++NDNMPFLFDS + E+ E E TLV HP+I V G + + G + Sbjct: 92 VTVITVVNDNMPFLFDSILGEITETSGEPTLVTHPVITVRHGKRGVEEILGDGNFAKDDG 151 Query: 143 KGARESLIHLHITRLDADSDRQKLIDGLTRTLNNVRACVADWRVMRDSVEEAIKTFSSNP 202 R S+IH+HI RL A++ L + L + L V A V DW+ M +++AI F + Sbjct: 152 SHDRLSVIHVHIPRLTAEA-ANALTERLRKMLGQVHAAVKDWKPMLARLDQAISEFRYSA 210 Query: 203 PPLPIDELAEANQFLQWLCADNFTFLGVRKYRFSPDSDASD-DITTGEGLGILRDPDVKV 261 PL +AEA FL+WL DNFTFLG+R++++S ++ + + GLGIL DPDV V Sbjct: 211 VPLDKTSVAEAIAFLEWLRDDNFTFLGMREFKYSGGEESGNLERADKPGLGILSDPDVLV 270 Query: 262 LRRGSEMVVMTPEIREFMHEPTLLIVIKANVSSRVHRRTRMDYVGIKLYSPDGRLEGELR 321 LRRG+E V TPEIR F+H P LIV KAN S VHRR +DY+G+K Y+P G L GELR Sbjct: 271 LRRGTEAVTTTPEIRAFLHGPEPLIVTKANAKSSVHRRIYLDYIGVKTYTPKGTLAGELR 330 Query: 322 VVGLFTSGAYTRSVRQIPYVRHKVSRVLQRAGFDPNGHSGKALMHILEDYPRDELFQIDV 381 +VGLFTS AYTRSV +IPY+R K V+ ++GFD + HSGKAL+++LE YPRDELFQ+ V Sbjct: 331 IVGLFTSTAYTRSVMKIPYLRSKAETVIAKSGFDRHDHSGKALINVLESYPRDELFQVPV 390 Query: 382 DTLYNFVIEILILYERPRVRALPRVDKFDRFVSILTFIPRDKYDTDVRTRVGSFLAQSYK 441 L IL L ERPRVRAL R D+FDRFVSIL F+PRD+YD+ VR ++G++L ++ Sbjct: 391 PILRRHAEAILGLVERPRVRALVRADQFDRFVSILVFVPRDRYDSVVREKIGAYLKNVFE 450 Query: 442 GKLSASYVSFPEGALARVHFIIGRYEGKTPVVDRALLEAGISAIAATWADKLKAALTAST 501 G+LSA Y +FPEG LARVHFIIGR GKTP V++A +EA I I TW D L A A Sbjct: 451 GRLSAYYPAFPEGGLARVHFIIGRSGGKTPKVEQATIEAAIRDIVRTWEDALSDAADAGG 510 Query: 502 DGMRARMLTNRYAQAFSGGYTEVFGAEQAIADITTVEKLTPARPVTISVYRIEGDDPRRF 561 + + R ++ Y + F A A+AD + +++ A P+ I YR P + Sbjct: 511 GDQALKAIAARLPES----YRDTFSAAVALADAGRIARISAANPIAIDYYRHAEQKPHQA 566 Query: 562 GLKVFSDAVPLSLSYRVPVIENHGLRVVNERTYQI-------VPGNRPEPVWLHDMTIET 614 LK++ P++LS RVPV+EN G RV++ERT+++ + ++P V++HDM +E Sbjct: 567 ALKIYHHGSPVALSRRVPVLENIGFRVISERTFEVGDDQSGTINSDQPGMVFIHDMELEN 626 Query: 615 SDGQPIEINPEFSHRLEASIMAVVTDRAESDGYNGLILRTALSWREVSTIRALSRYLHQI 674 S G+PI++ + E + ++V ++DGYNGL L E++ +RA RYL Q+ Sbjct: 627 SYGKPIDLT-DGGALFEDAFLSVWRGDVDNDGYNGLAQTAGLWSGEITILRAYGRYLQQV 685 Query: 675 RAPFTQDYMWETLRKNAAITASLVAMFQTRLDPRLVLTDRERTAREAALLAEIEEQLKPV 734 P +QD++ L + I L A+F RL P + E L A+I++ L+ V Sbjct: 686 GIPQSQDFIAAALNRYPDIARGLHALFIARLGP---TAETEGVVAAKHLKAKIKDALEDV 742 Query: 735 ASLDEDRILRRFTNLVQATVRTNLWQIGEDGHPRPVISFKFDARRIDDLPAPRPLYEIFV 794 ++D+D I+RR+ NL++A++RTN + + + ++ K +++ ++ LPAPRP EIFV Sbjct: 743 PNIDDDTIIRRYLNLIEASLRTNHF-VADTKQKGQSLAIKLESQAVEGLPAPRPWREIFV 801 Query: 795 YSPRVEGIHLRFGKVARGGLRWSDRPQDFRTEILGLVKAQQVKNAVIVPVGAKGGFVPKR 854 Y VEG+HLRFG VARGGLRWSDR QD+RTE+LGLVKAQQVKNAVIVPVGAKGGF PKR Sbjct: 802 YGSEVEGLHLRFGPVARGGLRWSDRAQDYRTEVLGLVKAQQVKNAVIVPVGAKGGFFPKR 861 Query: 855 LPPPARRDAWLAEGTESYRIFVRSLLELTDNLDGDIVVPPESTVRHDGDDPYLVVAADKG 914 LP RDA GT +Y+ FV SLL +TDN+ D V+PP VR D DDPY VVAADKG Sbjct: 862 LPAGGSRDAIFEAGTSAYKNFVSSLLSITDNIGLDGVIPPAGVVRRDQDDPYFVVAADKG 921 Query: 915 TATFSDVANAISAEKNHWLGDAFASGGSQGYDHKKMGITARGAWTAVKRHFRELGTDIQT 974 TATFSD ANAIS + WL DAFASGGS GYDHKKMGITA+GAW AVKRHFRE+ DIQT Sbjct: 922 TATFSDTANAISEKHGFWLDDAFASGGSAGYDHKKMGITAKGAWEAVKRHFREINRDIQT 981 Query: 975 MPFTAVGVGDMSGDVFGNGMLLSPATRLVAAFDHRDIFIDPSPDPSTSFAERKRLFDLPR 1034 PFT VGVGDMSGDVFGNGMLLSP TRL+AAFDHRDIFIDP PD + S AER+R+F LPR Sbjct: 982 SPFTVVGVGDMSGDVFGNGMLLSPQTRLIAAFDHRDIFIDPDPDMAASMAERERMFALPR 1041 Query: 1035 SSWQDYDKSLISQGGGVFSRSLKAIPLAPEVRTLLDLDKPQATPFEVMTAILKARADLLW 1094 SSWQDYDK+ +S+GG + SRS KAI L + L K ATP E+MTAILKA DLLW Sbjct: 1042 SSWQDYDKTKLSEGGVIVSRSQKAITLPVAAAAAIGLAKTTATPAEIMTAILKAPVDLLW 1101 Query: 1095 FGGIGTYVRSSGESDDQVGDRANDPIRIAGGDVRARVIGEGANLGVTQRGRIEAAQKGVK 1154 FGGIGTY+R+S E++ +VGDRAND IRI DVRA+VIGEGANLGVTQR RIE G + Sbjct: 1102 FGGIGTYLRASTETNAEVGDRANDAIRITALDVRAKVIGEGANLGVTQRARIEFGMNGGR 1161 Query: 1155 LNTDAIDNSAGVNTSDVEVNIKIALARPEREGRLSPADRNSLLAAMTDEVGALVLRNNYL 1214 N+DAIDNS GVN SDVEVNIKIALA R+G L+ RN LLA MT+EVG LVL NNY Sbjct: 1162 CNSDAIDNSGGVNCSDVEVNIKIALASAMRKGSLTRPARNKLLAEMTEEVGGLVLSNNYQ 1221 Query: 1215 QTLALSLAERKGVAETGFLTRLMQSLEQRGLLSRAVEFLPDDAALTERTRRGQSLARPEL 1274 QTLALS+A ++G+A+ R M +LE RGLL RAVE LP AAL ER RG+ L R EL Sbjct: 1222 QTLALSIARKRGLADIAHQARFMSALEARGLLDRAVETLPSPAALAEREARGEPLTRAEL 1281 Query: 1275 AVLLAYAKLTLYDDLLVTSVPDDPYLARELSQYFPREVQDKFPTAAGLHRLRREIIATSL 1334 VLLAYAK+ L+ D++ + VPDD + R+L YFP + K+ HRLRREIIA + Sbjct: 1282 GVLLAYAKIVLFSDIVASDVPDDAHFDRDLMGYFPDRMAKKYAAEIHGHRLRREIIARVV 1341 Query: 1335 ANAVINRGGPACVVRLIDETDADIPTIVMAYVAVDECFGLKWLNDAIDALDACIDGQLQL 1394 AN ++NRGGP+ V RL + T +V + V + F L L IDALD IDGQ+QL Sbjct: 1342 ANDLVNRGGPSFVNRLQEATGRTAADVVRTFAVVRDGFALPALYREIDALDNQIDGQVQL 1401 Query: 1395 SLYLSVQDLLLSRMVWYVRNVDFKDGLEAVVARFGPAIRQIVAGLDTALPPDLQAARVKR 1454 LY V L+ WY++N L +A A + + L + LP + ++ Sbjct: 1402 DLYQMVSRLIYVTSGWYLKNDAGTAPLGQRIAELQDARKALEPKLVSLLPAFSRERIEEK 1461 Query: 1455 RQELADAGVPAGLAGELADLDALVSAPDIVTVAERTTRPIGDAAATFYAAEANFRLDRII 1514 R L AG P LA +LA + PDI A I AA F+A FR+ R+ Sbjct: 1462 RHGLFKAGAPERLAEQLALSEVAELIPDIALTARTAGADIVAAARAFFAVSDAFRIPRVE 1521 Query: 1515 AAARSVPANDYFERMAIDRAVEQIAGAERRLAADMLATGQSGQQAVETWLAAHPE-ATRI 1573 AARS+ +DY++++A+ RA + I A R +A L V WL A E TRI Sbjct: 1522 DAARSITPSDYYDQLALSRATDTIGAARRGIAVAALTGHAKAADPVAAWLEAGGERVTRI 1581 Query: 1574 RRSVEEIAASG-LTLAKLTVAANLLGDL 1600 R ++ + G +T+++L+VA+ L+ DL Sbjct: 1582 RERLQALTEGGDITVSRLSVASGLMSDL 1609 >SMc04085 [E] COG2902 NAD-specific glutamate dehydrogenase Sme Sinorhizobium meliloti Length = 1595 Score = 1404 bits (3635), Expect = 0.0, Method: Compositional matrix adjust. Identities = 775/1612 (48%), Positives = 996/1612 (61%), Gaps = 47/1612 (2%) Query: 6 DKARAALIRDAAGSVPAGKSPRAFAEPLFGYTNIEDLANYDAASLALLAEQAWEHVQRRT 65 D ARAA R A ++P E LFG + +DL Y LAL A A + R Sbjct: 14 DAARAAGSRFGAETLPP--------EILFGGASNDDLDRYTPEMLALTAAHARGELARWD 65 Query: 66 AGSADIRV--VNPTLPNGREISVLEILNDNMPFLFDSTMAELAEQGLEVTLVAHPIIAVE 123 G + V V P G E+S++ I NMPFL+DS M E+ ++ L HPI+ +E Sbjct: 66 GGKPQVSVETVAGVAPGGIEVSIIAITERNMPFLYDSVMGEVTSTHRDIHLAIHPILVME 125 Query: 124 RDDGGKLLRFYGEALPEGAKGARESLIHLHITRLDADSDRQKLIDGLTRTLNNVRACVAD 183 KL E+ PE R S I +H++RL R L ++ L V V D Sbjct: 126 PGKPVKLFDPDEESAPE----HRVSHIQIHLSRLTPLEARS-LSKRISDVLEQVHQAVHD 180 Query: 184 WRVMRDSVEEAIKTFSSNPPPLPIDELAEANQFLQWLCADNFTFLGVRKYRFSPDSD-AS 242 W M +++A++ + EA FL+WL NFTFLG+R+Y +S A+ Sbjct: 181 WPAMTALLDQAMRELEDYNASRKKSDRDEALAFLRWLRDSNFTFLGMREYTYSGKGGRAT 240 Query: 243 DDITTGEGLGILRDPDVKVLRRGSEMVVMTPEIREFMHEPTLLIVIKANVSSRVHRRTRM 302 + G GLGIL +PDV+VLR+G + V+ TPEI F+ P LIV KANV S VHRR M Sbjct: 241 VERGKGRGLGILSNPDVRVLRQGKDAVLTTPEILAFLEGPDFLIVTKANVKSVVHRRAHM 300 Query: 303 DYVGIKLYSPDGRLEGELRVVGLFTSGAYTRSVRQIPYVRHKVSRVLQRAGFDPNGHSGK 362 DY+GIK + G + GELR+VGLFTS AYTR +IP +RHK+ +++ G+DP HSGK Sbjct: 301 DYIGIKRFDASGNVVGELRIVGLFTSTAYTRQASEIPLLRHKIEKIVDHFGYDPQSHSGK 360 Query: 363 ALMHILEDYPRDELFQIDVDTLYNFVIEILILYERPRVRALPRVDKFDRFVSILTFIPRD 422 L + LE YPRD+LFQIDV L F +I L +RPRVR LPR+D FDRFVS++ F+PR+ Sbjct: 361 TLANTLEAYPRDDLFQIDVGLLAAFCEQINELGDRPRVRVLPRIDHFDRFVSVIVFVPRE 420 Query: 423 KYDTDVRTRVGSFLAQSYKGKLSASYVSFPEGALARVHFIIGRYEGKTPVVDRALLEAGI 482 +YD+DVR ++G +L Y G++SA Y +FPEG LARVHFIIGR GKTP V +A LE + Sbjct: 421 QYDSDVREKIGDYLKTVYDGRVSAYYPAFPEGGLARVHFIIGRSGGKTPRVPQAKLEEAV 480 Query: 483 SAIAATWADKLKAALTASTDGMRARMLTNRYAQAFSGGYTEVFGAEQAIADITTVEKLTP 542 AI W D+ L A +G + Y F +A AD+ + T Sbjct: 481 RAIVTRWIDRFN--LLARKEGTEI---------SVGEAYQAAFTPAEAYADLGDIAACTA 529 Query: 543 ARPVTISVYRIEGDDPRRFGLKVFSDAVPLSLSYRVPVIENHGLRVVNERTYQI---VPG 599 P+ IS Y + P LK+F P+SLS RVP++EN G RV++E+TY I V G Sbjct: 530 GDPIRISFYHRHQERPDTLELKIFHADTPVSLSRRVPLLENLGFRVISEQTYDIGVHVHG 589 Query: 600 NRPEPVWLHDMTIETSDGQPIEINPEFSHRLEASIMAVVTDRAESDGYNGLILRTALSWR 659 + P V LHDM + DG + + LE + +A E D +N L+L L+ R Sbjct: 590 DEPREVVLHDMELIHRDGHTLNL-ARIGPALEEAFLAAWNGTTEDDNFNRLVLLAGLTAR 648 Query: 660 EVSTIRALSRYLHQIRAPFTQDYMWETLRKNAAITASLVAMFQTRLDPRLVLTDRERTAR 719 E++ +RA +RYL Q ++Q Y+ +TL K I A + +F TR+DP + + RT + Sbjct: 649 EITVLRAYARYLRQAGITYSQGYIADTLNKYPTIAADIFRLFSTRMDPTTEV--KARTKK 706 Query: 720 EAALLAEIEEQLKPVASLDEDRILRRFTNLVQATVRTNLWQIGEDGHPRPVISFKFDARR 779 +ALL IEE L V SLDEDRILRR+ N VQ+T+RTN +Q +G PR V++FK D ++ Sbjct: 707 CSALLTGIEEALSAVPSLDEDRILRRYVNAVQSTLRTNYFQKDAEGRPRAVLAFKLDPKQ 766 Query: 780 IDDLPAPRPLYEIFVYSPRVEGIHLRFGKVARGGLRWSDRPQDFRTEILGLVKAQQVKNA 839 ++ LP PRP EIFVY VEG+HLRFGKVARGGLRWSDR QD+RTE+LGLVKAQQVKNA Sbjct: 767 LEGLPEPRPFREIFVYGTEVEGVHLRFGKVARGGLRWSDRAQDYRTEVLGLVKAQQVKNA 826 Query: 840 VIVPVGAKGGFVPKRLPPPARRDAWLAEGTESYRIFVRSLLELTDNLDGDIVVPPESTVR 899 VIVPVGAKGGF PK+LP RD GTE+Y+ ++R+LL +TDN+ G VVPPE T+R Sbjct: 827 VIVPVGAKGGFYPKQLPVGGSRDEIFKAGTEAYKTYIRTLLSVTDNIIGQEVVPPEDTLR 886 Query: 900 HDGDDPYLVVAADKGTATFSDVANAISAEKNHWLGDAFASGGSQGYDHKKMGITARGAWT 959 DGDDPY VVAADKGTATFSD ANA++ E + WL DAFASGGS GYDHKKMGIT RGAW Sbjct: 887 LDGDDPYFVVAADKGTATFSDTANALAQEADFWLDDAFASGGSAGYDHKKMGITGRGAWE 946 Query: 960 AVKRHFRELGTDIQTMPFTAVGVGDMSGDVFGNGMLLSPATRLVAAFDHRDIFIDPSPDP 1019 AVKRHFRE+ DIQT PFT GVGDMSGDVFGNGMLLS RL+AAFDHRDIFIDP PD Sbjct: 947 AVKRHFREMDVDIQTTPFTVAGVGDMSGDVFGNGMLLSEKIRLIAAFDHRDIFIDPEPDI 1006 Query: 1020 STSFAERKRLFDLPRSSWQDYDKSLISQGGGVFSRSLKAIPLAPEVRTLLDLDKPQATPF 1079 SF ERKR+F LPRSSWQDYD+ +S G + SRS K + L PE + +DKP+ATPF Sbjct: 1007 DLSFGERKRMFALPRSSWQDYDRKALSPGAMIISRSEKLVTLTPEAMAAIGIDKPKATPF 1066 Query: 1080 EVMTAILKARADLLWFGGIGTYVRSSGESDDQVGDRANDPIRIAGGDVRARVIGEGANLG 1139 E+M+AILK+ DLLWFGGIGTYVR + E+D +VGDRAND IR++ DVRARVIGEGANLG Sbjct: 1067 EIMSAILKSPVDLLWFGGIGTYVRGANETDAEVGDRANDAIRVSAEDVRARVIGEGANLG 1126 Query: 1140 VTQRGRIEAAQKGVKLNTDAIDNSAGVNTSDVEVNIKIALARPEREGRLSPADRNSLLAA 1199 VTQ+GRI + G + N+DAIDNSAGVN+SDVEVNIKIALA R+ RL+ RN+LLA+ Sbjct: 1127 VTQKGRIGFSLNGGRCNSDAIDNSAGVNSSDVEVNIKIALASAMRDDRLTRPKRNTLLAS 1186 Query: 1200 MTDEVGALVLRNNYLQTLALSLAERKGVAETGFLTRLMQSLEQRGLLSRAVEFLPDDAAL 1259 MTDEVG LVLRNNY Q+LA+SL E +G+A L RLM LE G L+R VE LP D A+ Sbjct: 1187 MTDEVGHLVLRNNYQQSLAISLTEMQGLANRTPLARLMARLEADGHLNRKVETLPTDQAM 1246 Query: 1260 TERTRRGQSLARPELAVLLAYAKLTLYDDLLVTSVPDDPYLARELSQYFPREVQDKFPTA 1319 +ER + G+ L RPE+ VLL+YAKL L+D+L+V+ +PDDPY L +YFP +++ + Sbjct: 1247 SERYQAGRPLTRPEIGVLLSYAKLVLFDELIVSEIPDDPYFTATLERYFPAKMRKAYAGD 1306 Query: 1320 AGLHRLRREIIATSLANAVINRGGPACVVRLIDETDADIPTIVMAYVAVDECFGLKWLND 1379 HRLRREIIAT LAN INRGGPA V L D T +V A V + F L + Sbjct: 1307 IHGHRLRREIIATVLANETINRGGPAFVSTLTDATGFLSADVVKAAVLALDGFDLPRIYG 1366 Query: 1380 AIDALDACIDGQLQLSLYLSVQDLLLSRMVWYVRNVDFKDGLEAVVARFGPAIRQIVAGL 1439 IDALD I G +Q LY V + +R + + VAR ++++ + Sbjct: 1367 EIDALDNRISGAIQNRLYHEVGRIFALVAERALRTRASEGSVAEAVARLRDGLQKLRGTM 1426 Query: 1440 DTALPPDLQAARVKRRQELADAGVPAGLAGELADLDALVSAPDIVTVAERTTRPIGDAAA 1499 A+ + R + GV A LA E+A+L + P+I+ +A T P+ A Sbjct: 1427 RAAISREGAEEARLRAAGFIENGVSAKLAKEIAELSLMTLVPEIMQIATVTGEPLSRTAQ 1486 Query: 1500 TFYAAEANFRLDRIIAAARSVPANDYFERMAIDRAVEQIAGAERRLAADMLATGQSGQQA 1559 ++ + R++R++AAA VPA + FE MA+ RAV I A R + L + + Sbjct: 1487 AYFTVTESLRINRLLAAADRVPATEQFESMALSRAVGDIGTARRDITIAALVEHKGDRNP 1546 Query: 1560 VETWLAAHPEATRIRRSVEEIA--------ASGLTLAKLTVAANLLGDLVKA 1603 V W R R+ V + TLAK+TVAA LL DL + Sbjct: 1547 VLAW------QDRDRQRVATVGDQLRLLTEKGETTLAKVTVAAGLLSDLARG 1592 >AGc5015 [E] COG2902 NAD-specific glutamate dehydrogenase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1585 Score = 1396 bits (3613), Expect = 0.0, Method: Compositional matrix adjust. Identities = 771/1617 (47%), Positives = 1013/1617 (62%), Gaps = 47/1617 (2%) Query: 1 MAWRDDKARAALIRDAAGSVPAGKSPRAFAEP--LFGYTNIEDLANYDAASLALLAEQAW 58 M +R++ R I A A F +P L+G + +D+ Y A LA A ++ Sbjct: 1 MGYRNNPKREKQIEKARQQAIAENV--QFLDPGILYGRASADDIEYYSAEMLAASAAHSF 58 Query: 59 EHVQRRTAGSADIRV--VNPTLPNGREISVLEILNDNMPFLFDSTMAELAEQGLEVTLVA 116 E + T + I + V P ++VL I+ NMPFL+DS M E+ + L Sbjct: 59 EALSHWTGDAPHISITTVEGVSPRDIPVTVLTIIGRNMPFLYDSVMGEVTSSYRGLYLAV 118 Query: 117 HPIIAVERDDGGKLLRFYGEALPEGAKGARESLIHLHITRLDADSDRQKLIDGLTRTLNN 176 HPI+ RDD + R A PE SLI LHI L + L + L L Sbjct: 119 HPILV--RDDEAQGYRL---AEPEDDPAENISLIQLHIAPLTPQA-ASALEERLRFVLTQ 172 Query: 177 VRACVADWRVMRDSVEEAIKTFSSNPPPLPIDELAEANQFLQWLCADNFTFLGVRKYRFS 236 V++ DWR M ++EA+ S E EA +FL WL DNFTFLG+R Y +S Sbjct: 173 VQSAYRDWRPMLTKLDEALDELSKRGSSRRKTERTEAVEFLNWLRNDNFTFLGMRDYTYS 232 Query: 237 -PDSDASDDITTGEGLGILRDPDVKVLRRGSEMVVMTPEIREFMHEPTLLIVIKANVSSR 295 +A + G GLG L DPDV+VLR G V TPEI F+ P LIV KANV S Sbjct: 233 GKGKNAKIERGDGVGLGSLSDPDVRVLRLGKNAVTTTPEILAFLDGPDFLIVTKANVKSI 292 Query: 296 VHRRTRMDYVGIKLYSPDGRLEGELRVVGLFTSGAYTRSVRQIPYVRHKVSRVLQRAGFD 355 VHRR MDY+GIK + DG + GELR+VGLFT+ AYTRSV+QIP +R KV+ V + GFD Sbjct: 293 VHRRAYMDYIGIKRFDEDGNVIGELRIVGLFTATAYTRSVKQIPLLRAKVADVERHFGFD 352 Query: 356 PNGHSGKALMHILEDYPRDELFQIDVDTLYNFVIEILILYERPRVRALPRVDKFDRFVSI 415 PN HSG+ L + LE YPRD+LFQI+ D L F+ +I+ L +RPRVR L R+D+FDRFVS Sbjct: 353 PNSHSGRILQNTLEAYPRDDLFQIETDLLIRFIEQIMELSDRPRVRVLARIDRFDRFVSA 412 Query: 416 LTFIPRDKYDTDVRTRVGSFLAQSYKGKLSASYVSFPEGALARVHFIIGRYEGKTPVVDR 475 + F+PR++Y++ VR ++G +L++ Y G +SA Y +FPEGA+ARVHFI+GR EGKTP + + Sbjct: 413 IIFVPREEYNSYVREKIGDYLSRVYDGHISAYYPAFPEGAVARVHFIVGRTEGKTPRIAQ 472 Query: 476 ALLEAGISAIAATWADKLKAALTASTDGMRARMLTNRYAQAFSGGYTEVFGAEQAIADIT 535 LE +S IAA W D A S G + Y +AF+ E+AI D+ Sbjct: 473 DKLEDAVSDIAARWIDHFVAL---SEPGAPVLDVDQAYQEAFT--------PEEAIGDMP 521 Query: 536 TVEKLTPARPVTISVYRIEGDDPRRFGLKVFSDAVPLSLSYRVPVIENHGLRVVNERTYQ 595 + PV I Y+ EG LK+F L LS RVP++EN G V++ERT+ Sbjct: 522 DILAAANGEPVRIEFYQQEGQSDDTLSLKIFHRDGHLPLSRRVPLLENLGFNVISERTFD 581 Query: 596 I--VPGNRPEPVWLHDMTIETSDGQPIEINPEFSHRLEASIMAVVTDRAESDGYNGLILR 653 I V + LHDM + + G +++ P + +LE + +A + + ++D +N LIL Sbjct: 582 IGVVSEGEKRDIVLHDMELSVAAGTTLDL-PHYGPKLEEAFLAAFSGKVDNDNFNRLILA 640 Query: 654 TALSWREVSTIRALSRYLHQIRAPFTQDYMWETLRKNAAITASLVAMFQTRLDPRLVLTD 713 L+ REVS +RA +RYL Q ++Q+++ ETL K I+ ++ A+F+ DP + + Sbjct: 641 CGLNVREVSVLRAYARYLRQTGIVYSQEHISETLYKYPDISRNIFALFKAGFDPSI--EE 698 Query: 714 RERTAREAALLAEIEEQLKPVASLDEDRILRRFTNLVQATVRTNLWQIGEDGHPRPVISF 773 ++R + A + IE L V +LDEDR LRR+ N + AT+RTN +Q DG PR +++F Sbjct: 699 KKRVKKLAEIHKAIEAALSGVPNLDEDRTLRRYVNAIDATLRTNYFQKNADGTPRDLLAF 758 Query: 774 KFDARRIDDLPAPRPLYEIFVYSPRVEGIHLRFGKVARGGLRWSDRPQDFRTEILGLVKA 833 KFD + +D LP PRP EIFVY VEG+HLRFGKVARGGLRWSDR QD+RTE+LGLVKA Sbjct: 759 KFDPKHLDGLPDPRPFREIFVYGTEVEGVHLRFGKVARGGLRWSDRGQDYRTEVLGLVKA 818 Query: 834 QQVKNAVIVPVGAKGGFVPKRLPPPARRDAWLAEGTESYRIFVRSLLELTDNLDGDIVVP 893 QQVKNAVIVPVGAKGGF PK LP RD G E+Y+ ++R+LL +TDN+ D +VP Sbjct: 819 QQVKNAVIVPVGAKGGFFPKNLPAGGSRDEVFNAGREAYKTYIRTLLSITDNIVDDAIVP 878 Query: 894 PESTVRHDGDDPYLVVAADKGTATFSDVANAISAEKNHWLGDAFASGGSQGYDHKKMGIT 953 P T+R DGDDPY VVAADKGTATFSD AN ++ E WL DAFASGGS GYDHKKMGIT Sbjct: 879 PADTLRLDGDDPYFVVAADKGTATFSDTANGLAHEAGFWLDDAFASGGSAGYDHKKMGIT 938 Query: 954 ARGAWTAVKRHFRELGTDIQTMPFTAVGVGDMSGDVFGNGMLLSPATRLVAAFDHRDIFI 1013 ARGAW VKRHFRE+ TDIQT PFT GVGDMSGDVFGNGMLLS RL+AAFDHRDIFI Sbjct: 939 ARGAWETVKRHFREMDTDIQTTPFTVAGVGDMSGDVFGNGMLLSEKIRLIAAFDHRDIFI 998 Query: 1014 DPSPDPSTSFAERKRLFDLPRSSWQDYDKSLISQGGGVFSRSLKAIPLAPEVRTLLDLDK 1073 DP PD SFAERKRLF+LPRSSWQDYD+S +S G + SRS K++ L PE + LDK Sbjct: 999 DPDPDTDKSFAERKRLFELPRSSWQDYDRSTLSAGAMIISRSEKSVTLTPEAVAAIGLDK 1058 Query: 1074 PQATPFEVMTAILKARADLLWFGGIGTYVRSSGESDDQVGDRANDPIRIAGGDVRARVIG 1133 ATPFE+MTAILKA DLLWFGGIGTY++++ E++ +VGDRANDPIR+ ++RA+VIG Sbjct: 1059 SVATPFEIMTAILKAPTDLLWFGGIGTYIKAAVETNAEVGDRANDPIRVNATELRAKVIG 1118 Query: 1134 EGANLGVTQRGRIEAAQKGVKLNTDAIDNSAGVNTSDVEVNIKIALARPEREGRLSPADR 1193 EGANLG+TQ+GRI A G + N+DAIDNSAGVN+SDVEVNIKIALA GRL+ R Sbjct: 1119 EGANLGITQKGRIAYALAGGRCNSDAIDNSAGVNSSDVEVNIKIALASAVNSGRLTMPKR 1178 Query: 1194 NSLLAAMTDEVGALVLRNNYLQTLALSLAERKGVAETGFLTRLMQSLEQRGLLSRAVEFL 1253 N LLA+MT +V LVLRNNY Q+LA+SL ER G+A L RLM +LE G L+R VE L Sbjct: 1179 NQLLASMTPDVAQLVLRNNYQQSLAISLTERLGLANREELGRLMGALEATGQLNRKVETL 1238 Query: 1254 PDDAALTERTRRGQSLARPELAVLLAYAKLTLYDDLLVTSVPDDPYLARELSQYFPREVQ 1313 P++A +ER G+ L RPE+ VLL+YAKLTL+D L+ + +PD+PYL L YFP ++Q Sbjct: 1239 PNNAEFSERYASGKPLTRPEIGVLLSYAKLTLFDALVASPLPDEPYLQHLLLDYFPAKMQ 1298 Query: 1314 DKFPTAAGLHRLRREIIATSLANAVINRGGPACVVRLIDETDADIPTIVMAYVAVDECFG 1373 + HRL REI+AT+LANAV+NRGGP V +L D + +V A V V++ FG Sbjct: 1299 KNYANDIKAHRLHREIVATALANAVVNRGGPGFVQKLADASGLLAADVVKAAVIVEDGFG 1358 Query: 1374 LKWLNDAIDALDACIDGQLQLSLYLSVQDLLLSRMVWYVRNVDFKDGLEAVVARFGPAIR 1433 LK L +DALD + GQ+Q LY ++ + Y++ A I Sbjct: 1359 LKRLWTEVDALDGKVGGQVQNGLYATITRIFSDASRLYLQT----GSAGAAAGDMATEIE 1414 Query: 1434 QIVAGLDTALPPDLQAARVKRRQELADA---GVPAGLAGELADLDALVSAPDIVTVAERT 1490 ++ + T P A K R+EL GVP+GL EL L LV P+I+ +AE Sbjct: 1415 RLKTAIKTLSP-----AATKYRRELGVTEIDGVPSGLLEELDTLSLLVYVPEIMRIAESA 1469 Query: 1491 TRPIGDAAATFYAAEANFRLDRIIAAARSVPANDYFERMAIDRAVEQIAGAERRLAADML 1550 + AA ++ + FR+ R++ A++ + D++E +A+ R+ +QI+ + RR+ L Sbjct: 1470 GTTLARAAESYATVSSTFRVARLLDASQRITPADHYESLALLRSQDQISSSRRRIVISAL 1529 Query: 1551 ATGQSGQQAVETWLAAHPEATRIRRSVEEIAA---SGLT-LAKLTVAANLLGDLVKA 1603 + V+ W AA + R+ R V E+ A SG T LA+LTVAA LLGD+V+A Sbjct: 1530 TEYAKEKDPVQAWYAA--DRVRVNRIVSELGALSESGDTNLARLTVAAGLLGDIVQA 1584 >BMEI0231 [E] COG2902 NAD-specific glutamate dehydrogenase Bme Brucella melitensis Length = 1600 Score = 1348 bits (3489), Expect = 0.0, Method: Compositional matrix adjust. Identities = 734/1530 (47%), Positives = 952/1530 (62%), Gaps = 21/1530 (1%) Query: 79 PNGREISVLEILNDNMPFLFDSTMAELAEQGLEVTLVAHPIIAVERDDGGKLLRFYGEAL 138 P+ R +SV+ I+NDNMPFL DS M EL + ++ +V HP++ + R+ ++ L Sbjct: 86 PHSRPVSVITIVNDNMPFLLDSIMGELNDHTSQIFMVVHPVLDISREKDELVILGEASQL 145 Query: 139 PEGAKGARESLIHLHITRLDADSDRQKLIDGLTRTLNNVRACVADWRVMRDSVEEAIKTF 198 R SL+ +H+ L + + L GL R L VR+ V+DW+ M ++ AI + Sbjct: 146 APAKGVERVSLVQIHLPALSKQA-KADLTAGLKRVLGQVRSAVSDWKPMLKRLDGAIDDY 204 Query: 199 SSNPPPLPIDELAEANQFLQWLCADNFTFLGVRKYRFSPDSDASDDITTGEGLGILRDPD 258 + EA FL+WL D+F FLG+R+ F D + E LGIL D + Sbjct: 205 KRAYKLTGNAAMPEAIAFLEWLRDDHFIFLGLRELVFEGTGKKRDLVAAKEPLGILGDNE 264 Query: 259 VKVLRRGSEMVVMTPEIREFMHEPTLLIVIKANVSSRVHRRTRMDYVGIKLYSPDGRLEG 318 V+VLR+ + V EI EF+ LIV KAN S VHR + +DY+G+K++ G G Sbjct: 265 VRVLRKDDDDTVTPREITEFLDSAEPLIVTKANSLSSVHRCSYLDYIGVKIFGGRGEAIG 324 Query: 319 ELRVVGLFTSGAYTRSVRQIPYVRHKVSRVLQRAGFDPNGHSGKALMHILEDYPRDELFQ 378 ELR+VGLFTS AYT SV IP++R K V++ GF+ HSGKAL+++LE+YPRDELFQ Sbjct: 325 ELRLVGLFTSVAYTSSVAGIPFIRSKADAVIRHLGFNREDHSGKALINVLEEYPRDELFQ 384 Query: 379 IDVDTLYNFVIEILILYERPRVRALPRVDKFDRFVSILTFIPRDKYDTDVRTRVGSFLAQ 438 ID ++L IL L ERPRVRA+PR+D+F RF ++L +IPRD+YD+ VR ++G +L Sbjct: 385 IDTESLTANAELILALGERPRVRAIPRLDRFGRFATVLVYIPRDRYDSAVREKIGHYLVD 444 Query: 439 SYKGKLSASYVSFPEGALARVHFIIGRYEGKTPVVDRALLEAGISAIAATWADKLK-AAL 497 Y G + F + L RV F+I R+E TP VDR LEA + A+ W D ++ +A Sbjct: 445 VYGGDSFEFHPVFLQNGLTRVQFVIRRHERSTPHVDREALEAEVRAMVRNWEDAVRESAE 504 Query: 498 TASTDGMRARMLTNRYAQAFSGGYTEVFGAEQAIADITTVEKLTPARPVTISVYRIEGDD 557 T D T A +F Y E+F A +A+ D + L+P P+ + YR D Sbjct: 505 TVDAD-------TVALAASFPPSYREIFTAPEALVDAERIAGLSPEEPLFVDFYRYRTDG 557 Query: 558 PRRFGLKVFSDAVPLSLSYRVPVIENHGLRVVNERTYQI-VPGNRPEPVWLHDMTIETSD 616 P LK++ P+ LS RVP++EN G RVV+E+T + G PV+LHDM + + Sbjct: 558 PDAVSLKLYHHGAPVVLSQRVPLLENMGFRVVSEQTIDLPHAGKDGAPVYLHDMQLVNAY 617 Query: 617 GQPIEINPEFSHRLEASIMAVVTDRAESDGYNGLILRTALSWREVSTIRALSRYLHQIRA 676 G P++++ + LE V A++DGYN L+ L+ R++ +R+ RYL Q Sbjct: 618 GAPVDLSDD-GEMLEEVFRTVWDGLADNDGYNALVQTARLTARQIMILRSYGRYLQQAGI 676 Query: 677 PFTQDYMWETLRKNAAITASLVAMFQTRLDPRLVLTDRERTAREAALLAEIEEQLKPVAS 736 ++Q ++ L + I + L A+F R +P + + R A E L+ IE L V S Sbjct: 677 AYSQSFIAAALNRYPEIASDLYALFDLRSNP----SSKRRDAAEKKLVDAIETALLGVPS 732 Query: 737 LDEDRILRRFTNLVQATVRTNLWQIGEDGHPRPVISFKFDARRIDDLPAPRPLYEIFVYS 796 +D+D+ILRRF NL++AT+RTN +Q DG PR +FK + R +D LP PRP EIFVY Sbjct: 733 IDDDQILRRFRNLIEATLRTNAYQPDGDGKPRVTFAFKLNPRLVDGLPEPRPYREIFVYG 792 Query: 797 PRVEGIHLRFGKVARGGLRWSDRPQDFRTEILGLVKAQQVKNAVIVPVGAKGGFVPKRLP 856 P VEG+HLRFG VARGGLRWSDR QD+RTE+LGLVKAQQVKNAVIVPVGAKGGF PKRLP Sbjct: 793 PEVEGVHLRFGAVARGGLRWSDRAQDYRTEVLGLVKAQQVKNAVIVPVGAKGGFYPKRLP 852 Query: 857 PPARRDAWLAEGTESYRIFVRSLLELTDNLDGDIVVPPESTVRHDGDDPYLVVAADKGTA 916 R+A G ++Y++F+ +LL +TDN++ + VVPP VRHD DDPY VVAADKGTA Sbjct: 853 VGGDRNAVFEAGRDAYKVFISTLLSVTDNIEDNHVVPPTEVVRHDNDDPYFVVAADKGTA 912 Query: 917 TFSDVANAISAEKNHWLGDAFASGGSQGYDHKKMGITARGAWTAVKRHFRELGTDIQTMP 976 TFSD ANAIS + WL DAFASGGS GYDHK MGITARGAW AVKRHFRE DIQ+ P Sbjct: 913 TFSDTANAISQAHDFWLDDAFASGGSAGYDHKGMGITARGAWEAVKRHFREFDMDIQSEP 972 Query: 977 FTAVGVGDMSGDVFGNGMLLSPATRLVAAFDHRDIFIDPSPDPSTSFAERKRLFDLPRSS 1036 FT VGVGDMSGDVFGNGMLLS RLVAAFDHRDIFIDP+P P+ FAERKRLF+LPRSS Sbjct: 973 FTVVGVGDMSGDVFGNGMLLSEQIRLVAAFDHRDIFIDPNPVPADGFAERKRLFELPRSS 1032 Query: 1037 WQDYDKSLISQGGGVFSRSLKAIPLAPEVRTLLDLDKPQATPFEVMTAILKARADLLWFG 1096 WQDYD+S +S GGG++SRS K I L+ E + L K ATP E+MTAILK++ DLLWFG Sbjct: 1033 WQDYDRSKLSAGGGIYSRSQKTITLSAEASAAISLGKTTATPQEIMTAILKSKVDLLWFG 1092 Query: 1097 GIGTYVRSSGESDDQVGDRANDPIRIAGGDVRARVIGEGANLGVTQRGRIEAAQKGVKLN 1156 GIGTY+RSS E+D QVGDRAND IRI G +V ARVIGEGANLGVTQRGRIE A G + N Sbjct: 1093 GIGTYIRSSAETDAQVGDRANDAIRITGSEVGARVIGEGANLGVTQRGRIEYALAGGRGN 1152 Query: 1157 TDAIDNSAGVNTSDVEVNIKIALARPEREGRLSPADRNSLLAAMTDEVGALVLRNNYLQT 1216 TDAIDNSAGVN SDVEVNIKIALA R G+L RN LL +MTD+V LVLRNNYLQ Sbjct: 1153 TDAIDNSAGVNCSDVEVNIKIALAAAMRSGKLKRPARNKLLVSMTDDVSELVLRNNYLQP 1212 Query: 1217 LALSLAERKGVAETGFLTRLMQSLEQRGLLSRAVEFLPDDAALTERTRRGQSLARPELAV 1276 LALSL+ER G+AE + R M LE R LL R VE LP DA L ER + GQ L RPELAV Sbjct: 1213 LALSLSERLGLAELPYQARFMAELENRKLLDRKVENLPSDAVLAERQKAGQPLTRPELAV 1272 Query: 1277 LLAYAKLTLYDDLLVTSVPDDPYLARELSQYFPREVQDKFPTAAGLHRLRREIIATSLAN 1336 LLAYAKL+L DDL+ + +PD+PY L YFP+ + + HRL+REIIAT LAN Sbjct: 1273 LLAYAKLSLLDDLVASKLPDEPYFQSLLFGYFPKRMAKTYAEEISHHRLKREIIATLLAN 1332 Query: 1337 AVINRGGPACVVRLIDETDADIPTIVMAYVAVDECFGLKWLNDAIDALDACIDGQLQLSL 1396 +NRGG V RL D T I+ YVAV + F + + DAIDALD + G +Q Sbjct: 1333 DAVNRGGITFVSRLADTTGKSPADILRTYVAVRDGFEINAIYDAIDALDNQVPGDVQNQF 1392 Query: 1397 YLSVQDLLLSRMVWYVRNVDFKDGLEAVVARFGPAIRQIVAGLDTALPPDLQAARVKRRQ 1456 Y V ++L + W +RN + L +V A ++ D +P L++A + Sbjct: 1393 YHLVGEMLQATTAWVLRNDTTRANLTELVGTITRARAELEPRFDGLMPEYLKSALQADKA 1452 Query: 1457 ELADAGVPAGLAGELADLDALVSAPDIVTVAERTTRPIGDAAATFYAAEANFRLDRIIAA 1516 + G A LA LA+L PDI +A + AA ++A FR+ RI A Sbjct: 1453 AFMEKGASASLAQRLANLQLADIMPDIALIAHLAGADVVAAAKAYFAVSEAFRIGRIEDA 1512 Query: 1517 ARSVPANDYFERMAIDRAVEQIAGAERRLAADMLATGQSGQQAVETWLAAHPEATRI--- 1573 ARS+P DY++ +A+ RA + I A R + + A + ++ + RI Sbjct: 1513 ARSIPVADYYDGLALSRASDTITQAARGIT--IAALKRFAKEKDPAAAWLAADGARIEQV 1570 Query: 1574 -RRSVEEIAASGLTLAKLTVAANLLGDLVK 1602 R V LT+++L VAA L+ DL + Sbjct: 1571 KNRMVALTEGGDLTVSRLAVAAGLMSDLAQ 1600 >CC0088 [E] COG2902 NAD-specific glutamate dehydrogenase Ccr Caulobacter vibrioides Length = 1607 Score = 1244 bits (3220), Expect = 0.0, Method: Compositional matrix adjust. Identities = 689/1543 (44%), Positives = 944/1543 (61%), Gaps = 51/1543 (3%) Query: 86 VLEILNDNMPFLFDSTMAELAEQGLEVTLVAHPIIAVERDDGGKLLRFYGEALPEGAKGA 145 +LEI+ + PFL DS M E+ E G V + HP++ ++ G Sbjct: 90 LLEIVQPDRPFLVDSVMGEITESGFRVRAMFHPVVEID--------------------GI 129 Query: 146 RESLIHLHITRLDADSDRQKLIDGLTRTLNNVRACVADWRVMRDSVEEAIKTFSSNPPPL 205 S I +H+ + D + L++ + TL +VR V D++ MRD + A+ ++ P Sbjct: 130 ARSFIQVHLDPVGEDR-VESLLEQIRETLFDVRRAVGDFKAMRDLMHRAVAELAATPGVT 188 Query: 206 PIDELAEANQFLQWLCADNFTFLGVRKYRFSPDSD----ASDDITTGEG-LGILRDPDVK 260 + E FL+WL DNF FLG R Y + SD A + + E LG+LRD Sbjct: 189 SEEGRQEDLAFLRWLEDDNFVFLGARVYEYPRSSDGGYAAEEPLYEAEASLGVLRDSSRS 248 Query: 261 VLRRGSEMVVMTPEIREFMHEPTLLIVIKANVSSRVHRRTRMDYVGIKLYSPDGRLEGEL 320 VLRR E +++ +++ + ++V K+N+ SRVHRR MDYVG++ Y DG+ GE+ Sbjct: 249 VLRRAYEPAILSKQLQRQLETGAPVVVAKSNLRSRVHRRGFMDYVGVRRYGDDGKPSGEV 308 Query: 321 RVVGLFTSGAYTRSVRQIPYVRHKVSRVLQRAGFDPNGHSGKALMHILEDYPRDELFQID 380 R VGLFT+ AY ++P +RH+V+R+++RA P H+ K L +ILE +PRDELFQ Sbjct: 309 RFVGLFTAEAYETPAVEVPLIRHRVARIMRRAAKAPGSHNEKRLRNILETWPRDELFQTS 368 Query: 381 VDTLYNFVIEILILYERPRVRALPRVDKFDRFVSILTFIPRDKYDTDVRTRVGSFLAQSY 440 DTL + + +L L +RPRVR R+D FDRF S+L +IPR+++DT+V R G+ LA +Y Sbjct: 369 EDTLLSMALGVLHLIDRPRVRLFARLDPFDRFASVLVYIPRERFDTEVCARAGAILADAY 428 Query: 441 KGKLSASYVSFPEGALARVHFIIGRYEGKTPVVDRALLEAGISAIAATWADKLKAALTAS 500 GK+ Y + LAR HFII G P D + +EA I+ A TW D+ +A + A Sbjct: 429 DGKVLEYYPEISDAPLARAHFIIEVTPGDHPDPDLSQVEARIADTALTWEDRFEAVVRAG 488 Query: 501 ---TDGMRARMLTNRYAQAFSGGYTEVFGAEQAIADITTVEKLTPARPVTISVYRIEGDD 557 T G+R L ++Y AF GY + + A +A+ADI +E LT + +R D Sbjct: 489 GAPTGGVRT--LLDKYGYAFPPGYRDQYDALEALADIDIIETLTEGALPRVRAFRRFEDG 546 Query: 558 PRRFGLKVFSDAVPLSLSYRVPVIENHGLRVVNERTYQ--IVPGNRPEPVWLHDMTIETS 615 PR F K++ L+ +P++E GL+ + E ++ I + P VW+H+ ++ Sbjct: 547 PRTFRFKLYLRGAAAPLAEVLPILERMGLKALIEDGFRLSIHEKDGPHSVWVHEFVLDDP 606 Query: 616 DGQPIEINPEFSHRLEASIMAVVTDRAESDGYNGLILRTALSWREVSTIRALSRYLHQIR 675 G+ I + E E + +A+ T E+DG+N ++L A+ WRE + +RAL+RY Q Sbjct: 607 AGEHIVFD-EVRQVFEEAFIAIWTGATENDGFNRIVLEMAVGWREAALLRALARYRQQSG 665 Query: 676 APFTQDYMWETLRKNAAITASLVAMFQTRLDPRLVLTDRERTAREAALLAEIEEQLKPVA 735 +Q LR + + ++ +F+ + DP + R R + A+ I E L+ V Sbjct: 666 LDPSQQVQEAALRDHPMVARLILDLFRVKFDPAIRADLRTRREQAEAVQFSIVEALQAVE 725 Query: 736 SLDEDRILRRFTNLVQATVRTNLWQIGEDGHPRPVISFKFDARRIDDLPAPRPLYEIFVY 795 SLD DR+LRR LV A RTN +Q+G DG P+ ISFK +R ++DLPAP+P EI+V Sbjct: 726 SLDADRVLRRLAALVGAIQRTNFYQLGADGEPKSYISFKIASRELEDLPAPKPYREIYVS 785 Query: 796 SPRVEGIHLRFGKVARGGLRWSDRPQDFRTEILGLVKAQQVKNAVIVPVGAKGGFVPKRL 855 +P VEG+HLRFG VARGGLRWSDR DFRTE+LGLVKAQQVKNAVIVPVG+KGGF PK+L Sbjct: 786 APHVEGVHLRFGPVARGGLRWSDRRDDFRTEVLGLVKAQQVKNAVIVPVGSKGGFYPKQL 845 Query: 856 PPPARRDAWLAEGTESYRIFVRSLLELTDNLDGD-IVVPPESTVRHDGDDPYLVVAADKG 914 P RDA AE +Y+ F+ LL+LTDN+D D VVPP S + HD DPYLVVAADKG Sbjct: 846 PRGGDRDAIQAEAIRAYKTFLSGLLDLTDNIDSDNQVVPPPSVIAHDAQDPYLVVAADKG 905 Query: 915 TATFSDVANAISAEKNHWLGDAFASGGSQGYDHKKMGITARGAWTAVKRHFRELGTDIQT 974 TATFSD+AN ++ WLGDAFASGGS GYDHK MGITARGAW AVKRHFRELG DIQT Sbjct: 906 TATFSDIANGVAESYGFWLGDAFASGGSVGYDHKVMGITARGAWEAVKRHFRELGKDIQT 965 Query: 975 MPFTAVGVGDMSGDVFGNGMLLSPATRLVAAFDHRDIFIDPSPDPSTSFAERKRLFDLPR 1034 FT VGVGDMSGDVFGNGMLLS T+L+AAFDHR IF+DP+PDP+ S+AER R+F LPR Sbjct: 966 EAFTVVGVGDMSGDVFGNGMLLSKQTKLLAAFDHRHIFLDPNPDPAVSWAERDRMFKLPR 1025 Query: 1035 SSWQDYDKSLISQGGGVFSRSLKAIPLAPEVRTLLDLDKPQATPFEVMTAILKARADLLW 1094 SSW+DYDKS IS GGGVF+RSLK+IPL+ EVR +L++ +P E+MTAILK++A+LL+ Sbjct: 1026 SSWEDYDKSKISAGGGVFARSLKSIPLSAEVRAMLEIKAEAVSPAELMTAILKSKAELLY 1085 Query: 1095 FGGIGTYVRSSGESDDQVGDRANDPIRIAGGDVRARVIGEGANLGVTQRGRIEAAQKGVK 1154 GGIGTYV++ GE++ GD+AND IRI G D+R +V+GEGANLG+TQ GRIE AQ G Sbjct: 1086 LGGIGTYVKAKGETNADAGDKANDAIRINGSDLRVKVVGEGANLGLTQAGRIEFAQAGGH 1145 Query: 1155 LNTDAIDNSAGVNTSDVEVNIKIALARPEREGRLSPADRNSLLAAMTDEVGALVLRNNYL 1214 +NTDAIDNSAGV++SD EVNIKI ER G+L RN+LLA+MTD+V VL +NY Sbjct: 1146 INTDAIDNSAGVDSSDHEVNIKILTGILERGGQLDRESRNTLLASMTDDVAHHVLEHNYD 1205 Query: 1215 QTLALSLAERKGVAETGFLTRLMQSLEQRGLLSRAVEFLPDDAALTERTRRGQSLARPEL 1274 QTLAL+L E V+E R M +LEQRG L R VE LP + L ER G+ L RPEL Sbjct: 1206 QTLALTLLESDAVSEVDAQIRYMVNLEQRGRLDRRVEGLPTNTTLLERKAAGRGLTRPEL 1265 Query: 1275 AVLLAYAKLTLYDDLLVTSVPDDPYLARELSQYFPREVQDKFPTAAGLHRLRREIIATSL 1334 AVLLAY KL L+D+++ + PDDP+ R L YFPR + D++ A HRL+REIIAT + Sbjct: 1266 AVLLAYGKLDLFDEIVASQSPDDPWFERTLRGYFPRAL-DQYADAMQKHRLKREIIATVV 1324 Query: 1335 ANAVINRGGPACVVRLIDETDADIPTIVMAYVAVDECFGLKWLNDAIDALDACIDGQLQL 1394 N ++N GP V RL AD+ +V+ + A E G+ L D ++ LD + Q Sbjct: 1325 GNQMVNMCGPTFVSRLKAAAGADVNAVVVGFTAAREILGIDGLWDQVNGLDNKASAEGQT 1384 Query: 1395 SLYLSVQDLLLSRMVWYVRNVDFKDG--LEAVVARFGPAIRQIVAGLDTALPPDLQAARV 1452 +LY ++ L S W R +D ++ +V +GP++ + A L P Q A Sbjct: 1385 ALYKALAYALRSLTFWLARRAQ-RDAANVQTLVEAYGPSVAALKALAPAILSPFEQKAVS 1443 Query: 1453 KRRQELADAGVPAGLAGELADLDALVSAPDIVTVAERTTRPIGDAAATFYAAEANFRLDR 1512 KR + G P LA +A L L +A D+V +A ++ + + A ++ A F DR Sbjct: 1444 KRVKAYVADGAPEALALSVAALQPLTTAADLVDLANASSWSVENVARLYHQVGAAFGFDR 1503 Query: 1513 IIAAARSVPANDYFERMAIDRAVEQIAGAERRLAADML---ATGQSGQQ------AVETW 1563 + AA S D FER+A+ R +E + + + +L A Q+G+ A+ +W Sbjct: 1504 LRGAAGSFVGGDAFERLAVRRLIEDMLTEQTSITQQVLKFAANAQAGEDEAAAKAAISSW 1563 Query: 1564 LAAHPEATR-IRRSVEEI--AASGLTLAKLTVAANLLGDLVKA 1603 A + R ++R++E+I A G T AKLT+A L +L A Sbjct: 1564 AALRGDRPRAVKRTIEDIEQAGGGWTFAKLTIANAALRELSSA 1606