BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0206.p (407 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGpA441 [C] COG0372 Citrate synthase Atu Agrobacterium tumefacie... 241 2e-63 CC3643 [C] COG0372 Citrate synthase Ccr Caulobacter vibrioides 211 3e-54 mlr3843 [C] COG0372 Citrate synthase Mlo Mesorhizobium loti 199 1e-50 AGl71 [C] COG0372 Citrate synthase Atu Agrobacterium tumefaciens... 178 3e-44 SA1518 [C] COG0372 Citrate synthase Sau Staphylococcus aureus N315 145 1e-34 >AGpA441 [C] COG0372 Citrate synthase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 425 Score = 241 bits (615), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 166/410 (40%), Positives = 223/410 (54%), Gaps = 32/410 (7%) Query: 1 MKKSAELYLSAREAAAELAVSPATLYAYVSRGLIR-SEPSPDSRSHRYRAEDIRGLKERR 59 + + ++ +++A AAAEL +S ATLYAYVSRG+I S+ + D R Y A DI LK+R+ Sbjct: 32 IMRHSDKFMTADRAAAELGISRATLYAYVSRGMIHTSDAADDPRRRLYSAHDIEALKKRK 91 Query: 60 VPSPEPRGFRN--FDADLPVMDSAIATITEQGPIYRGVNCVELAERDTLEHTATLLWDVT 117 PR D LPV++SAI I E YRG + + L++ +LE A LLWD Sbjct: 92 NVGRRPRQVAAAALDWGLPVLESAITEIAEGQLRYRGQDALALSQAASLEDVARLLWDCG 151 Query: 118 GVDPF-----APDNCPQISDEMRAIAEAARRAQPIDRTVAVLALAASADPGAFTRAPDGR 172 VDPF AP PQ + + R +R A+L L + + R D R Sbjct: 152 EVDPFDDLKAAPTPWPQ------PVLDYVRDLPLTERCQALLPLLEAGRVTTWRR--DNR 203 Query: 173 AMVGGR--ILRLLVATMLNAAPSNELLHEQVARVWTPDNKHAPDLIRRALVLLADHELNA 230 + G +LR + +++ P + +H +A W D A DLIRRALVL ADHELN Sbjct: 204 RLWPGAAALLRGIAGACISSQPKTQAVHLSLADAWQTDAAGA-DLIRRALVLQADHELNT 262 Query: 231 STFTARCAASTGLNLYDAVIAGLVALKGPMHGGAGVLASRLVKTMLDN-----DVAPVVR 285 S F R ASTG +L + AGL AL GP+HGG + LV+ + D DV V+ Sbjct: 263 SAFAVRVVASTGASLGACLNAGLSALSGPLHGGM----TSLVEILFDELDRYGDVERVID 318 Query: 286 ERVALGERFAGFGHGVYKKGDPRAISLLEALTRAGAPRKFTREVPERIAEATGEFVNIDY 345 ER+ GE GF H +Y GDPRA LL L P E+ + + + TG+ D Sbjct: 319 ERLRRGEAIPGFRHPLYPDGDPRATGLLLYLP----PDAQRDELLQMMNDTTGQLPTCDV 374 Query: 346 ALAVLVHALRMPAGSELALFAMARSVGWIAHASEQLQHGKLIRPRARYVG 395 AL L +L++P G+ LALFA+AR+VGW+AHA EQ KLIRPRARY+G Sbjct: 375 ALVSLRRSLKLPRGAALALFAVARTVGWVAHALEQKLDDKLIRPRARYIG 424 >CC3643 [C] COG0372 Citrate synthase Ccr Caulobacter vibrioides Length = 388 Score = 211 bits (536), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 163/408 (39%), Positives = 202/408 (49%), Gaps = 33/408 (8%) Query: 9 LSAREAAAELAVSPATLYAYVSRGLIRSEPSP-DSRSHRYRAEDIRGLKERRVPSPEPRG 67 + A + L + P TLYAYVSRG I + P D R YRA D+ L ++ RG Sbjct: 1 MDAEQVLERLGIRPQTLYAYVSRGRIEAAAHPSDPRRSLYRASDVTALARKKA-----RG 55 Query: 68 FRNFDADL-------PVMDSAIATITEQGPIYRGVNCVELAERD-TLEHTATLLWDVTGV 119 R D PV+ SAI T++ YRG + LA++ TLE+ A LL G Sbjct: 56 RRVADVAAEAIAWGEPVLPSAITTVSGGKLWYRGEDAAGLADQGLTLENVARLLRGGHGA 115 Query: 120 DPFAPDNCPQ-ISDEMRAIAEAARRAQPIDRTVAVLALAASADPGAFTRAPDGRAMVGGR 178 A P +D R+ R LA A +P A RAP AM Sbjct: 116 ALKASSRPPPPATDSARS------------RMFLTLAERAGREPPARGRAPLALAMEAAD 163 Query: 179 ILRLLVATMLNAAPSNELLHEQVARVWTPDNKHAPDLIRRALVLLADHELNASTFTARCA 238 +L +V A + H++ A W A DL+RRALVL+ADHELNASTF AR A Sbjct: 164 LLDAIVDAATGQA-GDGPAHQRFAHAWNLTADGA-DLVRRALVLMADHELNASTFAARVA 221 Query: 239 ASTGLNLYDAVIAGLVALKGPMHGGAGVLASRLVKTMLDNDVAPVVRERVALGERFAGFG 298 ASTG +L A +AGL AL GP+HGG LV+ D A V R+ G GF Sbjct: 222 ASTGASLSAACLAGLSALSGPLHGGMAARVEALVEEADRRDAARAVSSRLEQGASLPGFD 281 Query: 299 HGVYKKGDPRAISLLEALTRAGAPRKFTREVPERIAEATGEFVNIDYALAVLVHALRMPA 358 H +Y GDPRA +L L R P T + + ATG NID+AL L L +P Sbjct: 282 HPLYPGGDPRAAAL---LARFEPPEPLT-ALWQATRAATGLAPNIDFALVALARGLALPQ 337 Query: 359 GSELALFAMARSVGWIAHASEQLQHGKLIRPRARYVGPAPGRAGTTNS 406 + LFA ARS GW AHA EQLQ G+LIRPRARY+G P AG + S Sbjct: 338 DAPFILFATARSAGWTAHAIEQLQTGRLIRPRARYIGTVPSAAGYSPS 385 >mlr3843 [C] COG0372 Citrate synthase Mlo Mesorhizobium loti Length = 379 Score = 199 bits (506), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 154/401 (38%), Positives = 200/401 (49%), Gaps = 35/401 (8%) Query: 8 YLSAREAAAELAVSPATLYAYVSRGLIRSEPS-PDSRSHRYRAEDIRGLKERRVPSPEPR 66 +LS EA L V P TLYAYVSRG I P D R +YRA+DI L RR P Sbjct: 4 WLSREEALERLRVRPQTLYAYVSRGRIGMRPDRADPRRSQYRADDIAALATRRARGRSPS 63 Query: 67 GFRN--FDADLPVMDSAIATITEQGPIYRGVNCVELAERDTLEHTATLLWDVTGVDPF-- 122 P + +AI+T+ IYRG + L++ TLE TA +LW + F Sbjct: 64 AIAESAIAWGEPSIATAISTVWHGHLIYRGRDAAVLSDNATLEETAAVLWGLPEPIRFEA 123 Query: 123 -APD--NCPQISDEMRAIAEAARRAQP-IDRTVAVLALAASADPGAFTRAPDGRAMVGGR 178 APD P + +A A +A+P + R+ A L A+ G Sbjct: 124 PAPDAPRQPGRASAFAQLALLAGQARPSLGRSAASLCADAARAIG--------------- 168 Query: 179 ILRLLVATMLNAAPSNELLHEQVARVWTPDNKHAPDLIRRALVLLADHELNASTFTARCA 238 ++A L A + +H ++AR W+ D+ A D IRRALVLLADHELNASTF AR A Sbjct: 169 ----VLAGALGAEAGPDPVHRRLARGWSVDDAGA-DAIRRALVLLADHELNASTFAARVA 223 Query: 239 ASTGLNLYDAVIAGLVALKGPMHGGAGVLASRLVKTMLDNDVAPVVRERVALGERFAGFG 298 ASTG + ++AGL L GP HGGAG +L + + +R + FG Sbjct: 224 ASTGASPAACLLAGLATLSGPRHGGAGEAVMQLAEDAARHGADAAIRRWLGHDRPLPAFG 283 Query: 299 HGVYKKGDPRAISLLEALTRAGAPRKFTREVPERIAEA-TGEFVNIDYALAVLVHALRMP 357 H +Y GDPR +L A+ P T + E+ A A TG NID+ALA L L +P Sbjct: 284 HPLYPDGDPRTTALSAAI-----PVDETLQQLEKAAIAMTGARPNIDFALAALTRGLGLP 338 Query: 358 AGSELALFAMARSVGWIAHASEQLQHGKLIRPRARYVGPAP 398 + LFA+ RSVGW AH EQ+ G +IRPR RY G P Sbjct: 339 RDAPFQLFALGRSVGWAAHMVEQIVSGSIIRPRGRYEGLLP 379 >AGl71 [C] COG0372 Citrate synthase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 294 Score = 178 bits (451), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 123/304 (40%), Positives = 162/304 (53%), Gaps = 29/304 (9%) Query: 104 DTLEHTATLLWDVTGVDPF-----APDNCPQISDEMRAIAEAARRAQPIDRTVAVLALAA 158 ++LE A LLWD VDPF AP PQ + + R +R A+L L Sbjct: 7 ESLEDVARLLWDCGEVDPFDDLKAAPTPWPQ------PVLDYVRDLPLTERCQALLPLLE 60 Query: 159 SADPGAFTRAPDGRAMVGGR--ILRLLVATMLNAAPSNELLHEQVARVWTPDNKHAPDLI 216 + + R D R + G +LR + +++ P + +H +A W D A DLI Sbjct: 61 AGRVTTWRR--DNRRLWPGAAALLRGIAGACISSQPKTQAVHLSLADAWQTDAAGA-DLI 117 Query: 217 RRALVLLADHELNASTFTARCAASTGLNLYDAVIAGLVALKGPMHGGAGVLASRLVKTML 276 RRALVL ADHELN S F R ASTG +L + AGL AL GP+HGG + LV+ + Sbjct: 118 RRALVLQADHELNTSAFAVRVVASTGASLGACLNAGLSALSGPLHGGM----TSLVEILF 173 Query: 277 DN-----DVAPVVRERVALGERFAGFGHGVYKKGDPRAISLLEALTRAGAPRKFTREVPE 331 D DV V+ ER+ GE GF H +Y GDPRA LL L P E+ + Sbjct: 174 DELDRYGDVERVIDERLRRGEAIPGFRHPLYPDGDPRATGLLLYLP----PDAQRDELLQ 229 Query: 332 RIAEATGEFVNIDYALAVLVHALRMPAGSELALFAMARSVGWIAHASEQLQHGKLIRPRA 391 + + TG+ D AL L +L++P G+ LALFA+AR+VGW+AHA EQ KLIRPRA Sbjct: 230 MMNDTTGQLPTCDVALVSLRRSLKLPRGAALALFAVARTVGWVAHALEQKLDDKLIRPRA 289 Query: 392 RYVG 395 RY+G Sbjct: 290 RYMG 293 >SA1518 [C] COG0372 Citrate synthase Sau Staphylococcus aureus N315 Length = 373 Score = 145 bits (366), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 112/364 (30%), Positives = 169/364 (46%), Gaps = 65/364 (17%) Query: 79 DSAIATITEQGPIYRGVNCVELAERDTLEHTATLLWDVT------------GVDPFAPDN 126 ++ I++I E Y G + +LAE E LLW+ ++ + N Sbjct: 15 ETKISSIIESQLTYAGYDIDDLAENAQFEEVIFLLWNYRLPNEEELAHLKGKLNQYMTLN 74 Query: 127 CPQISDEMRAIAEAARRAQPIDRTVAVLALAASADPGAFTRAPDGRAMVGGRILRLLVAT 186 P++ P+ L+ A DP A + + R RI + VA+ Sbjct: 75 -PRVYTHFEEYV--TDHVHPMTALRTSLSYIAHFDPDAENESDENRYERAMRI-QAKVAS 130 Query: 187 MLNAAPSNELLHEQVARVW--------TPDNKHAPDLI----------------RRALVL 222 ++ A ARV PD +A + + +AL+L Sbjct: 131 LVTA----------FARVRQDKEPLKPNPDLSYAANFLYMLRGELPTDIEVEAFNKALIL 180 Query: 223 LADHELNASTFTARCAASTGLNLYDAVIAGLVALKGPMHGGAGVLASRLVKTMLD----- 277 ADHELNAS FTARCA S+ ++Y ++A + +LKGP+HGG A+ V TML Sbjct: 181 HADHELNASAFTARCAVSSLSDMYSGIVAAVGSLKGPLHGG----ANEQVMTMLSEIGSI 236 Query: 278 NDVAPVVRERVALGERFAGFGHGVYKKGDPRAISLLE---ALTR-AGAPRKFTREVP--E 331 +V + E+ A ++ GFGH VYK GDPRA L E +T+ AG F V + Sbjct: 237 ENVDAYLDEKFANKDKVMGFGHRVYKDGDPRAKYLREMSRQITKDAGREELFEMSVKMEK 296 Query: 332 RIAEATGEFVNIDYALAVLVHALRMPAGSELALFAMARSVGWIAHASEQLQHGKLIRPRA 391 R+AE G N+D+ A + H + +P +FA++RS GWIAH EQ + +++RPRA Sbjct: 297 RMAEEKGLIPNVDFYSASVYHCMEIPHDLFTPIFAVSRSAGWIAHILEQYKDNRIMRPRA 356 Query: 392 RYVG 395 +Y+G Sbjct: 357 KYIG 360