BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0140.p (360 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC1568 [V] COG1680 Beta-lactamase class C and other penicillin b... 164 3e-40 MT1414 [V] COG1680 Beta-lactamase class C and other penicillin b... 150 4e-36 CC3190 [V] COG1680 Beta-lactamase class C and other penicillin b... 147 4e-35 DRA0218 [V] COG1680 Beta-lactamase class C and other penicillin ... 143 5e-34 CC1567 [V] COG1680 Beta-lactamase class C and other penicillin b... 143 7e-34 >CC1568 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Ccr Caulobacter vibrioides Length = 436 Score = 164 bits (415), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 95/238 (39%), Positives = 135/238 (56%), Gaps = 14/238 (5%) Query: 36 SAGPAAHSFSAEGLAKVSDYVRNEVATGKIPGAILLLQQHGKPVYYEKFGVRDVATEFSM 95 +A P + FSAEGL K+ +++ V G +PG +L +HGK V ++ G + M Sbjct: 34 AAAPESVGFSAEGLKKLDAHMQGLVDKGHLPGVTTMLVRHGKVVNFQVHGKKGFDGP-PM 92 Query: 96 SADTIFRLYSMSKPITTVIAMMLVEEGKLALGDPVSKYIPAFADMKV--GVEKRGDEGKM 153 + DT+FR+YS +KP+T V M+L EEGK L DPVSK+IP FA+++V GV G Sbjct: 93 TKDTVFRIYSQTKPVTGVAMMILFEEGKWTLDDPVSKFIPEFANLRVLKGVNADG----- 147 Query: 154 AMTLEPLRRPITIEDLMRHTAGLPYGYYGGGIVNKTYADAGLFNNDPDNAEFVARLAALP 213 + P RP T+ +LM H+AG YG ++K YAD L A+FV +A +P Sbjct: 148 SFDTVPAERPPTMRELMSHSAGFAYGLTPDNPLDKAYADKVLGAR--SRADFVKAIAEIP 205 Query: 214 LAEQPGTEWDYGHSTDVLGRIIEVITGKSLFQVEKERLLGPLGMNETAFYV----ADR 267 L +QPG W Y + D+ G I+E +TG SL K R+ PL M +T F++ ADR Sbjct: 206 LVDQPGKRWKYSIAVDIQGLIVEKLTGLSLGDFMKSRIFDPLKMKDTGFWLPAEKADR 263 >MT1414 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins MtC Mycobacterium tuberculosis CDC1551 Length = 401 Score = 150 bits (379), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 84/214 (39%), Positives = 120/214 (56%), Gaps = 7/214 (3%) Query: 56 VRNEVATGKIPGAILLLQQHGKPVYYEKFGVRDVATEFSMSADTIFRLYSMSKPITTVIA 115 +R G + GA+ ++ Q K + + G RD+ M DT+FR+ SM+KP+T A Sbjct: 10 IREVCDAGLLSGAVTMVWQREKLLQVNEIGYRDIDAGVPMQRDTLFRIASMTKPVTVAAA 69 Query: 116 MMLVEEGKLALGDPVSKYIPAFADMKVGVEKRGDEGKMAMTLEPLRRPITIEDLMRHTAG 175 M LV+EGKLAL DP++++ P + V + G + P RR I IEDL+ HT+G Sbjct: 70 MSLVDEGKLALRDPITRWAPELCKVAVLDDAAGPLDRT----HPARRAILIEDLLTHTSG 125 Query: 176 LPYGYYGGGIVNKTYADAGLFNNDPDNAEFVARLAALPLAEQPGTEWDYGHSTDVLGRII 235 L YG+ G +++ Y F PD ++A LA LPL QPG Y H+ DVLG I+ Sbjct: 126 LAYGFSVSGPISRAYQRLP-FGQGPD--VWLAALATLPLVHQPGDRVTYSHAIDVLGVIV 182 Query: 236 EVITGKSLFQVEKERLLGPLGMNETAFYVADRAK 269 I L+Q+ ER+LGP GM +T FYV+ A+ Sbjct: 183 SRIEDAPLYQIIDERVLGPAGMTDTGFYVSADAQ 216 >CC3190 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Ccr Caulobacter vibrioides Length = 490 Score = 147 bits (370), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 90/231 (38%), Positives = 132/231 (57%), Gaps = 11/231 (4%) Query: 39 PAAHSFSAEGLAKVSDYVRNE-VATGKIPGAILLLQQHGKPVYYEKFGVRDVATEFSMSA 97 P A S+E L ++ +++ + + TGK+P A+ + + G+ + G DV + A Sbjct: 86 PEAVGLSSERLKRIDSFIQAKYIDTGKLPCALTQVWRRGQLAHTSVLGSADVERGKPLKA 145 Query: 98 DTIFRLYSMSKPITTVIAMMLVEEGKLALGDPVSKYIPAFADMKVGVEKRGDEG--KMAM 155 D++FR+YSM+KPIT+V MMLVEEG +L DPV ++IPA+ D +GV + G G + Sbjct: 146 DSLFRIYSMTKPITSVAFMMLVEEGLASLDDPVHRFIPAWRD--IGVFQAGVAGAFQTTR 203 Query: 156 TLEPLRRPITIEDLMRHTAGLPYGYYGGGIVNKTYADAGLFNNDPDNA--EFVARLAALP 213 T EP+R TI DL+RHT+GL YG+ V+ Y L D + FV L +P Sbjct: 204 TKEPMR---TI-DLLRHTSGLTYGFQQRTNVDAAYRKLKLDGVDSEGGLKTFVETLGTVP 259 Query: 214 LAEQPGTEWDYGHSTDVLGRIIEVITGKSLFQVEKERLLGPLGMNETAFYV 264 L PG W+Y +TDVLG ++EVI+G K R+ PL M +T F+V Sbjct: 260 LEFSPGEAWNYSVATDVLGYLVEVISGMPFDVFLKTRIFDPLKMVDTGFFV 310 >DRA0218 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Dra Deinococcus radiodurans Length = 294 Score = 143 bits (361), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 82/204 (40%), Positives = 117/204 (57%), Gaps = 11/204 (5%) Query: 62 TGKIPGAILLLQQHGKPVYYEKFGVRDVATEFSMSADTIFRLYSMSKPITTVIAMMLVEE 121 +G +P A L+ + G+ Y G D+ + D +FR+YSM+KP+T++ +MLVEE Sbjct: 26 SGLLPNAQTLVYRRGELAYQSVLGFADMGARTPLREDHLFRIYSMTKPLTSLACLMLVEE 85 Query: 122 GKLALGDPVSKYIPAFADMKVGVEKRGDEGKMAMTLEPLRRPITIEDLMRHTAGLPYGYY 181 G+L+L DPVS +IPA+A++ V GD A T RP+ + DL+RHTAGL Y Sbjct: 86 GRLSLKDPVSAFIPAWAELNVHA---GDAPPTAPT-----RPMQVVDLLRHTAGLSYHIQ 137 Query: 182 GGGIVNKTYADAGL-FNNDPDNAEFVARLAALPLAEQPGTEWDYGHSTDVLGRIIEVITG 240 G + Y + L F A+FVA +A LPL PG W Y +TDVLG +++ + G Sbjct: 138 QGTATDALYRERRLGFGT--TLADFVAGIAELPLEYSPGEAWLYSAATDVLGYVVQQVAG 195 Query: 241 KSLFQVEKERLLGPLGMNETAFYV 264 Q KER+L PL M++T F V Sbjct: 196 VPFEQFLKERILTPLDMHDTDFQV 219 >CC1567 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Ccr Caulobacter vibrioides Length = 490 Score = 143 bits (360), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 87/240 (36%), Positives = 133/240 (55%), Gaps = 11/240 (4%) Query: 39 PAAHSFSAEGLAKVSDYVRNEVATGKIPGAILLLQQHGKPVYYEKFGVRDVATEFSMSAD 98 P FSAE L ++ D+++ V G+I G + +L +HG+ V FG R + + M D Sbjct: 64 PEEGGFSAERLKRLDDHMQTMVDRGQIAGGVTVLARHGRVVQARAFGRRVLGGD-PMPMD 122 Query: 99 TIFRLYSMSKPITTVIAMMLVEEGKLALGDPVSKYIPAFADMKV--GVEKRGDEGKMAMT 156 IFR+ S +KP+T V MML E+G L DPVS +IP FA+++V GV++ G Sbjct: 123 AIFRIRSETKPVTGVAMMMLYEQGLWRLDDPVSLHIPEFANLRVAKGVDETGQP-----I 177 Query: 157 LEPLRRPITIEDLMRHTAGLPYGYYG--GGIVNKTYADAGLFNNDPDNAEFVARLAALPL 214 L P+ R T+ +LM HTAG YG ++ Y A + + + V +++ LP+ Sbjct: 178 LTPVSRSPTMRELMTHTAGFAYGLANDPSSPADQAYYRAEVLQSA-SLTDLVQKVSGLPM 236 Query: 215 AEQPGTEWDYGHSTDVLGRIIEVITGKSLFQVEKERLLGPLGMNETAFYVADRAKWPLIA 274 +PG W Y + D+ G I+E ++G+SL +ER+ PLGM +TAFYV + + L A Sbjct: 237 FAEPGQLWRYSVAADIQGYIVEKLSGQSLPVFMQERIFTPLGMKDTAFYVPEEKQARLAA 296