BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0136.p (482 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb20891 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme S... 698 0.0 BMEI1740 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bme B... 689 0.0 mlr5236 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mlo Me... 662 0.0 CC0822 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Cau... 504 e-142 BS_ycbD [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Ba... 390 e-108 >SMb20891 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme Sinorhizobium meliloti Length = 477 Score = 698 bits (1802), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/480 (73%), Positives = 403/480 (83%), Gaps = 4/480 (0%) Query: 1 MTAHQKNFIAGEWVDGTGITRDINPSNTKDVVGEYAKADKAQTEKAIAAAKAAFPAWARS 60 MT HQ N IAGEWV G G+ +INPSNT DVVGEYA+A + AIAAAKAAFPAW+RS Sbjct: 1 MTLHQ-NLIAGEWVGGDGVA-NINPSNTDDVVGEYARASAEDAKAAIAAAKAAFPAWSRS 58 Query: 61 TPQERFDALTRISVEILARKEELGRLLAREEGKTLPEGIGEVARAGQIFAFFAGEALRLM 120 ER L + + EILARK+ELGRLL+REEGKTL EGIGE RAGQIF FFAGE LRL Sbjct: 59 GILERHAILKKTADEILARKDELGRLLSREEGKTLAEGIGETVRAGQIFEFFAGETLRLA 118 Query: 121 GEKGASVRPGLDVEITREPVGVVGMITPWNFPIAIPAWKIAPALCYGNAVVFKPAELVPG 180 GE SVRPG+ VEITREP GVVG+ITPWNFPIAIPAWK+APALCYGN +VFKPAELVPG Sbjct: 119 GEVVPSVRPGIGVEITREPAGVVGIITPWNFPIAIPAWKLAPALCYGNTIVFKPAELVPG 178 Query: 181 SAHALSEIIARSGIPSGVFNLVVGSGSVVGQTLLDHPDVAAISFTGSVQTGRKIAQACVL 240 + A+ +I+ R+G+P GV NLV+G GSVVGQ +LD PDV AI+FTGS TG+++A A V Sbjct: 179 CSWAIVDILHRAGLPKGVLNLVMGKGSVVGQAMLDSPDVQAITFTGSTATGKRVAVASVE 238 Query: 241 SNPMKKFQLEMGGKNPLVVLDDADVKVAVEVAVNGAYFSTGQRCTASSRLIVTAGIHDRF 300 N +K+QLEMGGKNP VVLDDAD+ VAVE AVN A+FSTGQRCTASSR+IVT GIHDRF Sbjct: 239 HN--RKYQLEMGGKNPFVVLDDADLSVAVEAAVNSAFFSTGQRCTASSRIIVTEGIHDRF 296 Query: 301 VAAMTERMKGLSVDDALKSGVHVGPVVDQSQLDQDLRYIKIGQDEGARLHWGGELLNRET 360 VAAM ER+KGL VDDALK G H+GPVVDQSQL+QD YI IG+ EGA+L +GGE+++R+T Sbjct: 297 VAAMGERIKGLVVDDALKPGTHIGPVVDQSQLNQDTDYIAIGKQEGAKLAFGGEVISRDT 356 Query: 361 PGFYLQPALFTEATNQMRIAREEIFGPVACVIRAKDYEEALAISNDTEFGLASGICTTSL 420 PGFYLQPALFTEATN+MRI+REEIFGPVA VIR KDY+EALA++NDT FGL+SGI TTSL Sbjct: 357 PGFYLQPALFTEATNEMRISREEIFGPVAAVIRVKDYDEALAVANDTPFGLSSGIATTSL 416 Query: 421 KYASHYKRNSEAGMVMVNLPTAGVDYHVPFGGRKGSSYGAREQGAYAREFYTTVKTAYTF 480 K+A+H+KRN+EAGMVMVNLPTAGVD+HVPFGGRK SSYG REQG YA EFYT VKTAYT Sbjct: 417 KHATHFKRNAEAGMVMVNLPTAGVDFHVPFGGRKASSYGPREQGKYAAEFYTNVKTAYTL 476 >BMEI1740 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bme Brucella melitensis Length = 477 Score = 689 bits (1777), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/480 (72%), Positives = 401/480 (83%), Gaps = 4/480 (0%) Query: 1 MTAHQKNFIAGEWVDGTGITRDINPSNTKDVVGEYAKADKAQTEKAIAAAKAAFPAWARS 60 MT HQ N IAGEWV G I +INPS+T DVVG YA+A T+ AIAAAKAAFPAW+RS Sbjct: 1 MTFHQ-NLIAGEWVGGDDIA-NINPSDTNDVVGTYARATAEDTKAAIAAAKAAFPAWSRS 58 Query: 61 TPQERFDALTRISVEILARKEELGRLLAREEGKTLPEGIGEVARAGQIFAFFAGEALRLM 120 ER L + + EILARKEELGRLL+REEGKTL EGIGE RA QIF FFAGE LRL Sbjct: 59 GILERHAILRKTADEILARKEELGRLLSREEGKTLVEGIGETIRASQIFDFFAGECLRLA 118 Query: 121 GEKGASVRPGLDVEITREPVGVVGMITPWNFPIAIPAWKIAPALCYGNAVVFKPAELVPG 180 GE S RPG+ VE+TREPVGVVG+ITPWNFPIAIPAWKIAPALCYGN +VFKPAELVPG Sbjct: 119 GEVLPSARPGIGVEVTREPVGVVGIITPWNFPIAIPAWKIAPALCYGNTIVFKPAELVPG 178 Query: 181 SAHALSEIIARSGIPSGVFNLVVGSGSVVGQTLLDHPDVAAISFTGSVQTGRKIAQACVL 240 + A+++I+ R+G+P GV NLV+G GSVVGQT+LD DV A +FTGS TG+++A A + Sbjct: 179 CSWAIADILHRAGLPKGVLNLVMGKGSVVGQTILDSADVNAATFTGSTGTGKRVAAASIE 238 Query: 241 SNPMKKFQLEMGGKNPLVVLDDADVKVAVEVAVNGAYFSTGQRCTASSRLIVTAGIHDRF 300 N ++FQLEMGGKNP+VVLDDAD+ VAVE VN A+FSTGQRCTASSR+IVT GIHD+F Sbjct: 239 HN--RRFQLEMGGKNPVVVLDDADLNVAVESVVNSAFFSTGQRCTASSRIIVTEGIHDKF 296 Query: 301 VAAMTERMKGLSVDDALKSGVHVGPVVDQSQLDQDLRYIKIGQDEGARLHWGGELLNRET 360 VAA E++K + VD+ALK G H+GPVVD++QL QD+ YI++G+ EGA+L +GGE LNRET Sbjct: 297 VAAAIEKLKTVVVDNALKPGTHIGPVVDETQLQQDMDYIELGRKEGAKLAFGGERLNRET 356 Query: 361 PGFYLQPALFTEATNQMRIAREEIFGPVACVIRAKDYEEALAISNDTEFGLASGICTTSL 420 PGFYLQPALFTEATNQMRI+REEIFGPVA VIR KDYEEALA +NDT FGL+SGICTTSL Sbjct: 357 PGFYLQPALFTEATNQMRISREEIFGPVASVIRVKDYEEALATANDTSFGLSSGICTTSL 416 Query: 421 KYASHYKRNSEAGMVMVNLPTAGVDYHVPFGGRKGSSYGAREQGAYAREFYTTVKTAYTF 480 KYA+H+KRNSEAGMVMVNLPTAGVD+HVPFGGRKGSS+G REQG YA EFYTTVKTAYT Sbjct: 417 KYATHFKRNSEAGMVMVNLPTAGVDFHVPFGGRKGSSFGPREQGRYAAEFYTTVKTAYTL 476 >mlr5236 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mlo Mesorhizobium loti Length = 479 Score = 662 bits (1707), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/482 (69%), Positives = 389/482 (80%), Gaps = 3/482 (0%) Query: 1 MTAHQKNFIAGEWVDGTGITRDINPSNTKDVVGEYAKADKAQTEKAIAAAKAAFPAWARS 60 M +KN I GEWV G + +INPS+T DVVGEYA A Q ++AIAAAKAAFP+W+RS Sbjct: 1 MAQFRKNLIDGEWVGDAG-SHNINPSDTGDVVGEYASAGVEQAKQAIAAAKAAFPSWSRS 59 Query: 61 TPQERFDALTRISVEILARKEELGRLLAREEGKTLPEGIGEVARAGQIFAFFAGEALRLM 120 P R L + S EI+ARK+E+GR LAREEGKTL EGIGE RA QIF FFAGE LRL Sbjct: 60 GPLARHAVLKKASDEIMARKDEIGRNLAREEGKTLAEGIGETIRAAQIFDFFAGETLRLT 119 Query: 121 GEKGASVRPGLDVEITREPVGVVGMITPWNFPIAIPAWKIAPALCYGNAVVFKPAELVPG 180 GE SVRPG+ VEITRE VGVVG+ITPWNFPIAIPAWKIAPAL +GN +VFKPAELVP Sbjct: 120 GEMVPSVRPGVGVEITREAVGVVGIITPWNFPIAIPAWKIAPALAHGNTIVFKPAELVPE 179 Query: 181 SAHALSEIIARSGIPSGVFNLVVGSGSVVGQTLLDHPDVAAISFTGSVQTGRKIAQACVL 240 SA ++ +I+ R+G+P GV NLV+G GSVVGQ +LD PD+ AI+FTGSV TG+++A A V Sbjct: 180 SAWSIVDILHRAGLPKGVLNLVMGKGSVVGQAMLDSPDINAITFTGSVGTGKRVAAASV- 238 Query: 241 SNPMKKFQLEMGGKNPLVVLDDADVKVAVEVAVNGAYFSTGQRCTASSRLIVTAGIHDRF 300 M+KFQLEMGGKNPLVVLDDAD+ VAV+ A+NGA+FSTGQRCTASSRLIVT IHDRF Sbjct: 239 -EHMRKFQLEMGGKNPLVVLDDADLAVAVDCALNGAFFSTGQRCTASSRLIVTEDIHDRF 297 Query: 301 VAAMTERMKGLSVDDALKSGVHVGPVVDQSQLDQDLRYIKIGQDEGARLHWGGELLNRET 360 V A+ ERM L + DAL + +GPVVD +QL QD YI IG EGA L +GGE L+R+T Sbjct: 298 VEALKERMGKLVIGDALDAQTQIGPVVDATQLKQDEDYIAIGVREGATLAFGGERLDRKT 357 Query: 361 PGFYLQPALFTEATNQMRIAREEIFGPVACVIRAKDYEEALAISNDTEFGLASGICTTSL 420 PGFYL PAL TEATN MR +REEIFGPVA VIR K+Y+EAL+++NDT FGL SGICTTSL Sbjct: 358 PGFYLSPALLTEATNAMRSSREEIFGPVASVIRVKNYDEALSVANDTPFGLTSGICTTSL 417 Query: 421 KYASHYKRNSEAGMVMVNLPTAGVDYHVPFGGRKGSSYGAREQGAYAREFYTTVKTAYTF 480 K+A+H+KRNSEAGMVMVNLPTAGVD+HVPFGGRKGSSYG REQG YA EFYTTVKTAYTF Sbjct: 418 KHATHFKRNSEAGMVMVNLPTAGVDFHVPFGGRKGSSYGPREQGRYATEFYTTVKTAYTF 477 Query: 481 PG 482 G Sbjct: 478 AG 479 >CC0822 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Caulobacter vibrioides Length = 478 Score = 504 bits (1299), Expect = e-142, Method: Compositional matrix adjust. Identities = 255/480 (53%), Positives = 332/480 (69%), Gaps = 3/480 (0%) Query: 1 MTAHQKNFIAGEWVDGTGITRDINPSNTKDVVGEYAKADKAQTEKAIAAAKAAFPAWARS 60 MT +++I GE V +NPSNT DVV + +A+ + A+ AA+ AFPAWA + Sbjct: 1 MTDTLRHYIGGERVAADAPAESLNPSNTNDVVAKVPMGGQAEVDAAVDAARKAFPAWADA 60 Query: 61 TPQERFDALTRISVEILARKEELGRLLAREEGKTLPEGIGEVARAGQIFAFFAGEALRLM 120 +P+ R D L ++ I+AR ++GRLLAREEGKTL EGIGE RAG+IF +FAGEALR Sbjct: 61 SPEVRSDLLDKVGSTIIARSADIGRLLAREEGKTLAEGIGETVRAGRIFKYFAGEALRRH 120 Query: 121 GEKGASVRPGLDVEITREPVGVVGMITPWNFPIAIPAWKIAPALCYGNAVVFKPAELVPG 180 G+ S RPG++++ R+ VGV G+ITPWNFPIAIPAWK APAL +GN VV KPA P Sbjct: 121 GQNLESTRPGVEIQTYRQAVGVYGLITPWNFPIAIPAWKAAPALAFGNTVVIKPAGPTPA 180 Query: 181 SAHALSEIIARSGIPSGVFNLVVGSGSVVGQTLLDHPDVAAISFTGSVQTGRKIAQACVL 240 +A+ L++I+A G P+GVFN++ G GS+ G L+ H DV +SFTGS A Sbjct: 181 TANVLADIMAECGAPAGVFNMLFGRGSM-GDALIKHKDVDGVSFTGSQGV--GAQVAAAA 237 Query: 241 SNPMKKFQLEMGGKNPLVVLDDADVKVAVEVAVNGAYFSTGQRCTASSRLIVTAGIHDRF 300 + QLEMGGKNPL+VLDDAD++ AV +A++G++F+TGQRCTASSRLIV GIHD+F Sbjct: 238 VARQARVQLEMGGKNPLIVLDDADLERAVAIALDGSFFATGQRCTASSRLIVQDGIHDKF 297 Query: 301 VAAMTERMKGLSVDDALKSGVHVGPVVDQSQLDQDLRYIKIGQDEGARLHWGGELLNRET 360 VA + E++ L V DAL +GP V + Q++ RYI I EG R+ GG+ + + Sbjct: 298 VALLAEKVAALRVGDALDPNTQIGPAVSEDQMETSYRYIDIAASEGGRVVTGGDRIKLDN 357 Query: 361 PGFYLQPALFTEATNQMRIAREEIFGPVACVIRAKDYEEALAISNDTEFGLASGICTTSL 420 PG+Y++P L + MRI EE+FGPVA IR K YEEAL I+N EFGL++GI TTSL Sbjct: 358 PGWYVRPTLIADTQAGMRINNEEVFGPVASTIRVKSYEEALEIANGVEFGLSAGIATTSL 417 Query: 421 KYASHYKRNSEAGMVMVNLPTAGVDYHVPFGGRKGSSYGAREQGAYAREFYTTVKTAYTF 480 K+A H++R + AGM MVNL TAGVDYHVPFGG K SSYGAREQG A EF+T KT+Y++ Sbjct: 418 KHARHFQRYARAGMTMVNLATAGVDYHVPFGGTKSSSYGAREQGFAAVEFFTQTKTSYSW 477 >BS_ycbD [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Bacillus subtilis Length = 488 Score = 390 bits (1003), Expect = e-108, Method: Compositional matrix adjust. Identities = 213/479 (44%), Positives = 298/479 (62%), Gaps = 6/479 (1%) Query: 7 NFIAGEWVDGTG--ITRDINPSNTKDVVGEYAKADKAQTEKAIAAAKAAFPAWARSTPQE 64 NFI GEWV + + NP++ D+VG + E+A+ AA A AW + T E Sbjct: 12 NFINGEWVKSQSGDMVKVENPADVNDIVGYVQNSTAEDVERAVTAANEAKTAWRKLTGAE 71 Query: 65 RFDALTRISVEILARKEELGRLLAREEGKTLPEGIGEVARAGQIFAFFAGEALRLMGEKG 124 R L + + + R EE+ RE GKTLPE GE AR I ++AGE +R G+ Sbjct: 72 RGQYLYKTADIMEQRLEEIAACATREMGKTLPEAKGETARGIAILRYYAGEGMRKTGDVI 131 Query: 125 ASVRPGLDVEITREPVGVVGMITPWNFPIAIPAWKIAPALCYGNAVVFKPAELVPGSAHA 184 S + TR P+GVVG+I+PWNFP+AIP WK+APAL YGN VV KPA + Sbjct: 132 PSTDKDALMFTTRVPLGVVGVISPWNFPVAIPIWKMAPALVYGNTVVIKPATETAVTCAK 191 Query: 185 LSEIIARSGIPSGVFNLVVGSGSVVGQTLLDHPDVAAISFTGSVQTGRKIAQACVLSNPM 244 + +G+P+GV NLV G GSVVGQ L +H V A++FTGS Q G+ I QA + Sbjct: 192 IIACFEEAGLPAGVINLVTGPGSVVGQGLAEHDGVNAVTFTGSNQVGKIIGQAALARGA- 250 Query: 245 KKFQLEMGGKNPLVVLDDADVKVAVEVAVNGAYFSTGQRCTASSRLIVTAGIHDRFVAAM 304 K+QLEMGGKNP++V DDAD++ A E + GA+ STGQ+CTA+SR+IV +GI++RF + Sbjct: 251 -KYQLEMGGKNPVIVADDADLEAAAEAVITGAFRSTGQKCTATSRVIVQSGIYERFKEKL 309 Query: 305 TERMKGLSVDDALKSGVHVGPVVDQSQLDQDLRYIKIGQDEGARLHWGGELLN--RETPG 362 +R K +++ D+LK V +GP+ ++QLD L YI+ G+ EGA L GGE L + G Sbjct: 310 LQRTKDITIGDSLKEDVWMGPIASKNQLDNCLSYIEKGKQEGASLLIGGEKLENGKYQNG 369 Query: 363 FYLQPALFTEATNQMRIAREEIFGPVACVIRAKDYEEALAISNDTEFGLASGICTTSLKY 422 +Y+QPA+F T++M IA+EEIFGPV +I+ EEAL I+ND +FGL++ I T ++ Sbjct: 370 YYVQPAIFDNVTSEMTIAQEEIFGPVIALIKVDSIEEALNIANDVKFGLSASIFTENIGR 429 Query: 423 ASHYKRNSEAGMVMVNLPTAGVDYHVPFGGRKGSSYGAREQGAYAREFYTTVKTAYTFP 481 + +AG+V +N +AGV+ PFGG K SS +REQG A++F+T +KT + P Sbjct: 430 MLSFIDEIDAGLVRINAESAGVELQAPFGGMKQSSSHSREQGEAAKDFFTAIKTVFVKP 488